Abstract: A syringe press includes a housing, a compressible member, and a compression mechanism. The housing includes a longitudinal axis, a first end and a second end. The housing is configured to support a syringe, which includes a cylinder configured to contain a fluid, and a piston having a seal configured to move within the cylinder, between the first and second ends. The compressible member is supported by the housing between the first end and the piston. The compression mechanism is supported by the housing and is configured to apply a compressive force to the piston, the cylinder and the compressible member, between the first and second ends and along the longitudinal axis. The piston is driven into the cylinder, and fluid is driven through an output of the cylinder responsive to the compressive force.

Abstract: A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures.

Abstract: A method for diffusion magnetic resonance imaging may be provided. The method may comprise steps of performing sampling on an object at N diffusion weighted directions to acquire undersampled but complementary k-space data, combining the complementary data from different directions to obtain a full sampled k-space data, performing initial reconstruction based on common information among images at the N diffusion weighted directions, and performing joint iterative regularized reconstruction to k-space data in all diffusion weighted directions based on the initial images to obtain the desired final images. Due to the utilization of common information at the N diffusion weighted directions, the acquisition efficiency may be enhanced and image resolution and SNR of acquired images may be improved accordingly.

Abstract: In one aspect, the invention relates to substituted (E)-N?-(1-phenylethylidene)benzohydrazide analogs, derivatives thereof, and related compounds, which are useful as inhibitors of lysine-specific histone demethylase, including LSD1; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of using the compounds and compositions to treat disorders associated with dysfunction of the LSD1. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

Abstract: A system for location-based construction project management includes a design information storage section for storing a 2D plot or a 3D model of a building, a work place code storing means, being deployed at each work place of the building, and for storing location information of the work place, a wireless terminal being provided with local information of the work place and location information in addition to the work place code storing means, a work place mapping section for mapping the location information and a locational numeric data of the work place within the 2D plot or the 3D model stored in the design information storage section and a construction information storage section for storing the local information being provided into the wireless terminal, as linked with the locational numeric data mapped by the work place mapping section.

Abstract: Provided herein are inventive enopeptin compounds of Formula (I): and pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Further provided are methods of preparation, use, and treatment.

Abstract: The present invention relates to active robotic gait training system and method which enables more active gait training based on remaining gait ability of patients with gait disorders by estimating the gait cycle through measurement of slope of the lower leg, operating the hip joint and the knee joint by an actuator depending on the gait cycle and operating the ankle joint by functional electric stimulation (FES). The robotic gait training system contains the femoral support unit, the hip joint support unit and the lower leg support unit.

Abstract: Compositions and methods related to stromal antigen 2 (STAG2) and its role in diverse human cancers, including nucleic acids, polypeptides, vectors, cells and cell lines.

Abstract: Methods of treating pain by delivery of anti-inflammatory cytokines, proinflammatory cytokine antagonists, and agents that act to reduce or prevent proinflammatory cytokine actions, to the nervous system are described. These agents can be delivered using gene therapy techniques. Alternatively, the agents can be delivered in protein compositions.

Abstract: A method of forming composite materials includes mixing a first metal precursor with a chelating agent to form a first metal-chelate complex. The first metal-chelate complex is added to a polymer binder having terminating hydroxyl groups to form a polymer binder-first metal-chelate. The polymer binder first metal-chelate complex is mixed with an aluminum precursor. The aluminum precursor decomposes forming aluminum nanoparticles dispersed in a continuous phase material having metallic aluminum cores. At least one of the first metal-chelate complex and the first metal is dissolved in the continuous phase. The aluminum nanoparticles can have a passivating coating layer thereon provided by the polymer binder, or can have a passivating coating layer formed by including an epoxide, alcohol, carboxylic acid, or amine in the adding that forms passivating compound(s) which add further protection that can provide complete protection from oxidation of the metallic aluminum cores by air.

Abstract: There is provided a semiconductor device including a first channel-type first MISFET formed and a second channel-type second MISFET: a first source and a first drain of the first MISFET and a second source and a second drain of the second MISFET are made of the same conductive substance, and the work function ?M of the conductive substance satisfies at least one of relations respectively represented by (1) ?1<?M<?2+Eg2, and (2) |?M??1|?0.1 eV and |(?2+Eg2)??M|?0.1 eV, where ?1 represents an electron affinity of an N-type semiconductor crystal layer, and ?2 and Eg2 represent an electron affinity and a band gap of a crystal of a P-type semiconductor crystal layer.

Abstract: It is an object of the present invention to provide a delta-5 desaturase-defective gene and uses of the gene and/or the mutant in algal transformation.

Abstract: A ruthenium complex for a dye-sensitized solar cell includes a chemical formula represented by Formula (I): RuL1L2L3??(I) where L1 represents a monodentate ligand; L2 represents a tridentate ligand of and L3 represents a bidentate ligand of where R1 to R27 have meaning as defined in the specification.

Abstract: A checkpointing method for creating a file representing a restorable state of a virtual machine in a computing system, comprising identifying processes executing within the virtual machine that may store confidential data, and marking memory pages and files that potentially contain data stored by the identified processes; or providing an application programming interface for marking memory regions and files within the virtual machine that contain confidential data stored by processes; and creating a checkpoint file, by capturing memory pages and files representing a current state of the computing system, which excludes information from all of the marked memory pages and files.

Abstract: Systems and methods for inhibiting bone loss using FoxP3+ CD8 T-cells (TcREG). Osteoclasts are induced to produce FoxP3+ CD8 T-cells (TcREG) either in vivo or ex vivo. The FoxP3+ CD8 T-cells (TcREG) are provided to the patient to subsequently regulate osteoclast function, thereby establishing a bi-directional regulatory loop between osteoclasts and FoxP3+ CD8 T-cells(TcREG).

Abstract: The present invention relates to MAGEA3 binding antibodies.

Abstract: The present invention addresses the problem of providing a vaccine which as yet has not been provided for the disease HHV-6B, which is the cause of exanthema subitum in infants, and the problem of providing an effective screening method for other therapeutic drugs. The above-mentioned problems are solved by providing an epitope specific to HHV-6B, of the amino acid sequence (QALCEGGHVFYNP) represented by positions 484 to 496 of SEQ ID NO: 2 or a modified sequence thereof, wherein the epitope either has a sequence comprising at least five consecutive amino acids including at least E, or a sequence that preserves the 487th C and 489th G when E is changed to Q.

Abstract: The present disclosure provides methods and devices for locating a plurality of interested objects in CT imaging. Location of the interested objects in the three-dimensional space can be determined by using three projection images that are substantially perpendicular to each other. The method can rapidly locate interested objects in a CT image without pre-reconstruction of the CT image even if there are a plurality of interested objects in the field of view. The algorithm does not involve interactive steps. The method is rapid and effective, and thus applicable to industrial applications.

Abstract: The present disclosure provides a method for making touch panel. A carbon nanotube structure is formed on a substrate. The carbon nanotube structure includes a number of carbon nanotubes. The number of carbon nanotubes are arranged isotropically, arranged along a same direction, or arranged along different directions. Two electrodes are electrically connected with the carbon nanotube structure. Furthermore, a primary alignment direction of the number of carbon nanotubes and a surface of the carbon nanotube structure in contact with the substrate is greater than 0° and smaller than 15°.

Abstract: A non-adherent cell support for use as a substrate in fluidic chambers used for cell culturing and assays. The non-adherent cell support allows for the formation of sphere cultures from single cells, which can better mimic primary tumor-like behavior in the study of cancer stem cells. The non-adherent cell support can allow for adhesive culturing and may include a hydrophobic substrate having a lower body and a raised support structure extending upwardly from an upper surface of the body. The support structure comprises one or more vertically extending support members that extend from a proximal portion at the upper surface of the body to a distal end spaced from the upper surface of the body. The support structure may be formed from a biocompatible material such as poly-2-hydroxyethyl methacrylate, polydimethylsiloxane, polymethyl methacrylate, polystyrene, or a polyethylene glycol diacrylate-based hydrogel.