Abstract: Embodiments are directed compositions related to Eilat virus and uses thereof.

Abstract: The present invention provides methods of assessing an individual subject's risk of developing prostate cancer, comprising: a) analyzing a nucleic acid sample obtained from the subject and determining a genotype for the subject at a plurality of biallelic polymorphic loci, wherein each of said plurality has an associated allele and an unassociated allele, wherein the genotype is selected from the group consisting of homozygous for the associated allele, heterozygous, and homozygous for the unassociated allele; and b) calculating a cumulative relative risk (CRR) for the subject based on the genotype determined in step (a). A CRR of greater than 1.00 identifies a subject as having an increased risk of developing prostate cancer and also can identify a subject who is a candidate for early PSA screening, prostate biopsy and/or chemoprevention.

Abstract: Technologies are generally described for automatically optimizing an efficiency of camera placement, numbers, and resolution in multi-camera monitoring and surveillance applications. In some examples, a fraction of a total area may be monitored at a higher resolution than the rest. Employing techniques such as combinatorial state Viterbi technique or combinatorial state trellis technique, a minimum number of cameras that provide the coverage at the needed resolution may be selected. Similarly, a number of points may be covered with at least a predefined number of cameras. For example, a subject of interest may be tracked in a public area, where specific camera(s) may be used to image the subject's face at a higher resolution than the background.

Abstract: The here described invention discloses a combination of a top and bottom loop binder library using the CD and the FG loops of a number of FnIII domains (FnIII) (e.g., FnIII7, FnIII10 and FnIII14) together with the surface exposed residues of the beta-sheet. The invention also pertains to a method of forming a library of FnIII domain polypeptides useful in screening for the presence of one or more polypeptides having a selected binding or enzymatic activity.

Abstract: The present invention is produced by a composite with an Eu (II) compound nanoparticle and a metal nanoparticle. Such production generates quantum size effects of the Eu (II) compound nanoparticle, while the surface plasmon of the metal nanoparticle can be used. Thus, the magnetooptical property can be improved. In addition, a thin film may be produced by a composite with an Eu (II) compound nanoparticle and a metal nanoparticle.

Abstract: A locally gated graphene nanostructure is described, along with methods of making and using the same. A graphene layer can include first and second terminal regions separated by a substantially single layer gated graphene nanoconstriction. A local first gate region can be separated from the graphene nanoconstriction by a first gate dielectric. The local first gate region can be capacitively coupled to gate electrical conduction in the graphene nanoconstriction. A second gate region can be separated from the graphene nanoconstriction by a second gate dielectric. The second gate region can be capacitively coupled to provide a bias to a first location in the graphene nanoconstriction and to a second location outside of the graphene nanoconstriction. Methods of making and using locally gated graphene nanostructures are also described.

Abstract: The current invention is a novel gyroscope design, which yields devices robust to fabrication and environmental variations, allows flexible selection of operational parameters, and provides increased bandwidth with minimized sacrifice in gain regardless of the selected frequency of operation. The gyroscope has a single degree-of-freedom (DOF) drive-mode and a 2-DOF sense-mode. The drive-mode operational frequency and the sense-mode bandwidth can be selected arbitrarily in the proposed design, relaxing the tradeoff between the gain, die size, and detection capacitance. The symmetry of the structure ensures the optimal location of the drive-mode resonance relative to the sense-mode operational region, even in presence of fabrication imperfections.

Abstract: Provided is a method for producing a polyhydroxyalkanoic acid (PHA). More particularly, a method of preparing PHA containing a high content of long-chain aromatic monomer-units by growing a phaZ mutant of a Pseudomonas strain in a medium containing a sugar, a substituted fatty acid, and a salicylic acid.

Abstract: It is an object of the invention to provide novel approaches capable of detecting activated protease and also detecting protease activation on real time at a high sensitivity in a noninvasive manner. By the method for detecting activated protease of the invention, an indicator in a circular form comprising the C-half fragment of luciferase (Luc-C) and the N-half fragment of luciferase (Luc-N) linked together through a substrate peptide for a protease is introduced in an in vitro assay system or in cells. Upon digestion of the substrate peptide by the protease, Luc-N and Luc-C together reconstructs active luciferase, so that the activated protease can be detected by assaying the luminescence signal from the luciferase.

Abstract: A chipset package structure includes a carrier, a plurality of pinouts, at least one semiconductor package preforms, at least one electromagnetic shielding layer and a protective layer. The pinouts are disposed on the carrier. The semiconductor package preforms is disposed on the second surface of the carrier and electrically connected to the pinouts. The electromagnetic shielding layer is disposed on the semiconductor package preforms and the electromagnetic shielding layer. At least one of the electromagnetic shielding layers comprises a carbon nanotube film structure. The protective layer covers the electromagnetic shielding layer.

Abstract: The graft copolymer comprises a polymerizable monomer (A1) represented by general formula (III) and a polymerizable monomer (B1) containing a pyridyl group, and a ligand can be bonded via the functional group at the terminus of R3a. In the formula, R1a represents a polymerizable group, R2a represents an alkylene group having a carbon number of 2-5, R3a represents an organic group having at a terminus a functional group selected from among an azide group, a phenyl azide group, a carboxyl group, a primary to quaternary amino group, an acetal group, an aldehyde group, a thiol group, a disulfide group, an active ester group, a trialkoxysilyl group, and a polymerizable group, and n represents any integer from 5 to 20,000.

Abstract: A substation-control center tow-level distributed grid nonlinear state estimation method is provided. RTU measurement data and PMU measurement data at each voltage level in each substation are collected. Performing a first three-phase state estimation is performed to obtain a first estimation result. Bad data from the RTU measurement data and the PMU measurement data are removed to estimate a state of a CB. A new CB island at each voltage level is formed, and a second three-phase state estimation for the new CB island is performed to obtain a final estimation result, in which the new CB island is a bus. The final estimation result is processed to obtain ripe data. And the ripe data, a part of the RTU measurement data and a part of the PMU measurement data are collected and a whole grid state estimation is performed.

Abstract: To decode a representation of a codeword that encodes K information bits as N>K codeword bits, messages are exchanged between N bit nodes and N?K check nodes of a graph in which E edges connect the bit nodes and the check nodes. While messages are exchanged, fewer than E of the messages are stored, and/or fewer than N soft estimates of the codeword bits are stored. In some embodiments, the messages are exchanged only within sub-graphs and between the sub-graphs and one or more external check nodes. While messages are exchanged, the largest number of stored messages is the number of edges in the sub-graph with the most edges plus the number of edges that connect the sub-graphs to the external check node(s), and/or the largest number of stored soft estimates is the number of bit nodes in the sub-graph with the most bit nodes.

Abstract: An intravascular diagnostic or therapeutic apparatus capable of removing blood in an intravascular lumen to be observed using a minimally invasive method is provided. The apparatus includes high-intensity pulsed light generating means and high-intensity pulsed light transmitting means for transmitting high-intensity pulsed light, capable of irradiating the interior of a blood vessel with high-intensity pulsed light, producing water-vapor bubbles and temporarily removing the blood in the blood vessel.

Abstract: Embodiments of the present invention provided a method of fabricating a semiconductor light source structure. The method comprises providing a GaAs substrate; forming a lower cladding layer above the substrate, the lower cladding layer comprising an AIxGa1-xAs alloy; forming an active region above the lower cladding layer, the active region comprising a GaAs separate confinement heterostructure; and forming an upper cladding layer comprising an AIxGa1-xAs alloy above the active region in the form of an elongate stripe bounded on either side by an InGaP current-blocking layer, the elongate stripe defining an index-guided optical waveguide.

Abstract: The present invention relates to a HIF-l? activator containing clioquinol and its derivatives as an active ingredient. Clioquinol and its derivatives of the invention inhibit HIF-1?(hypoxia-inducible factor-l?) ubiquitination in normoxic cells and thus accumulate HIF-l?. In the meantime, CQ inhibits FIH-I activity and thereby induces transcription activity of the accumulated HIF-l?, resulting in the induction of expressions of HIF-l? target genes VEGF (vascular endothelial growth factor) and EPO (erythropoietin). Therefore, clioquinol and its derivatives can be effectively used as a therapeutic agent for ischemic disease.

Abstract: A self-powered ‘near field’ lithographic system 100 includes three primary components, namely, a thin film or emitter substrate 110 including a radioactive material (e.g., a radioisotope 112), a target substrate 120 which carries an energy-modifiable layer 122 (e.g., photo-resist) and a stencil (e.g., 130) that is either positioned between the emitter and target substrates fabricated upon and defined in the emitter substrate. The stencil is made from a material capable of blocking particles emitted through radioactive decay from the radioisotope of the emitter substrate. The stencil includes openings or vias 132 patterned to permit selective transmission of the particles emitted through radioactive decay from the radioisotope of the emitter substrate 110, and the stencil is preferably placed up against (or very close to) the target substrate 120.

Abstract: The present invention employs three decoupled hardware mechanisms: read and write signatures, which summarize per-thread access sets; per-thread conflict summary tables, which identify the threads with which conflicts have occurred; and a lazy versioning mechanism, which maintains the speculative updates in the local cache and employs a thread-private buffer (in virtual memory) only in the rare event of an overflow. The conflict summary tables allow lazy conflict management to occur locally, with no global arbitration (they also support eager management). All three mechanisms are kept software-accessible, to enable virtualization and to support transactions of arbitrary length.

Abstract: An acoustic signal generation system may include a cylindrical-like object having a cylindrical-like surface which is configured to reflect an acoustic signal directed to a location on the surface in substantially different directions as the cylindrical-like object is rotated. The cylindrical-like surface may be on the exterior of the cylindrical-like object or form an interior surface of the cylindrical-like object. The cylindrical-like surface may be formed by a plurality of substantially flat surfaces connected to one another in a substantially cylindrical configuration. The flat surfaces may have different angular orientations with respect to the axis of rotation. An acoustic transducer may be configured and oriented so as to direct an acoustic signal to a location on the cylindrical-like surface as the cylindrical-like object rotates. A motor may be configured to cause the cylindrical-like object to rotate.

Abstract: Devices for generating streamwise vorticity in a boundary includes various forms of vortex generators. One form of a split-ramp vortex generator includes a first ramp element and a second ramp element with front ends and back ends, ramp surfaces extending between the front ends and the back ends, and vertical surfaces extending between the front ends and the back ends adjacent the ramp surfaces. A flow channel is between the first ramp element and the second ramp element. The back ends of the ramp elements have a height greater than a height of the front ends, and the front ends of the ramp elements have a width greater than a width of the back ends.