Patents Assigned to University
  • Methods for decreasing steroidogenesis in prostate cancer cells
    Patent number: 8680055
    Abstract: The present invention discloses compositions and methods for treating diseases such as cancer by targeting luteinizing hormone (LH) or its receptor (LHR) involved in androgen synthesis or testosterone production.
    Type: Grant
    Filed: June 2, 2010
    Date of Patent: March 25, 2014
    Assignee: University of Southern California
    Inventor: Jacek Pinski
  • Porin B (PorB) as a therapeutic target for prevention and treatment of infection by
    Patent number: 8679510
    Abstract: The present invention features peptides of a PorB polypeptide, which PorB peptides are useful in production of antibodies that bind the full-length PorB polypeptide and as a therapeutic agent. In specific embodiments the invention features a composition comprising one or more PorB peptides (other than a full-length PorB polypeptide), which peptides contain at least one epitope that can elicit Chlamydia-neutralizing antibodies. The invention also features methods for induction of a protective immune response against infection by Chlamydia and Chlamydiophila.
    Type: Grant
    Filed: November 20, 2012
    Date of Patent: March 25, 2014
    Assignee: The Regents of the University of California
    Inventors: Richard S. Stephens, Diane Kawa
  • Tris-Quaternary Ammonium Salts and Methods for Modulating Neuronal Nicotinic Acetylcholine Receptors
    Publication number: 20140080866
    Abstract: Provided are tris-quaternary ammonium compounds which are modulators of nicotinic acetylcholine receptors. Also provided are methods of using the compounds for modulating the function of a nicotinic acetylcholine receptor, and for the prevention and/or treatment of central nervous system disorders, substance use and/or abuse and/or gastrointestinal tract disorders.
    Type: Application
    Filed: November 26, 2013
    Publication date: March 20, 2014
    Applicant: University of Kentucky Research Foundation
    Inventors: Peter Crooks, Linda DWOSKIN, Roger Papke, Guangrong ZHENG, Sangeetha SUMITHRAN
  • METHOD OF INHIBITING APOLIPOPROTEIN-E EXPRESSION COMPRISING ADMINISTERING A TRIARYLMETHYL AMINE COMPOUND
    Publication number: 20140080209
    Abstract: This invention offers an effective method of inhibiting the expression of apolipoprotein E by mammalian cells. Apolipoprotein E is a protein that plays a significant role in the development of Alzheimer's Disease in humans. The method comprises administering an effective amount of a triarylmethyl amine compound having the general formula: wherein the R1 group may comprise acyclic amines and aliphatic amines. The R2 group may comprise one of three aryl varieties: aryl, substituted aryl, or heterocycle. Triarylamine compounds inhibit apolipoprotein E expression in mammalian cells. In one aspect of the invention the mammalian cells may be human cells, and more specifically may be human brain cells.
    Type: Application
    Filed: November 26, 2013
    Publication date: March 20, 2014
    Applicant: California State University Fresno
    Inventor: Santanu Maitra
  • LIFETIME OLED DISPLAY
    Publication number: 20140077177
    Abstract: Light emitting devices including sub-pixels having different numbers of emissive layers are provided. At least one sub-pixel of a first color may include a single emissive layer, and at least one sub-pixel of a second color may include multiple emissive layers disposed in a vertical stack. Light emitting devices in which different voltages are applied to each sub-pixel or group of sub-pixels are also provided. In some configurations, the voltage to be applied to a sub-pixel may be selected based upon the number of emissive layers in the sub-pixel.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 20, 2014
    Applicant: Universal Display Corporation
    Inventors: Michael HACK, Julia J. Brown, Michael Stuart Weaver, Mauro Premutico
  • AGENTS TO TREAT/PREVENT AMOEBIASIS
    Publication number: 20140079775
    Abstract: The invention provides formulations comprising isolated lacto-N-tetraose (LNT) or galactooligosaccharides (GOS) or variants, isomers, analogs and derivatives thereof and a pharmaceutically acceptable carrier.
    Type: Application
    Filed: February 3, 2012
    Publication date: March 20, 2014
    Applicant: The Regents of the University of California
    Inventors: Lars Bode, Tineke Lauwaet, Evelyn Jantscher-Krenn, Frances Gillin
  • CONTINUOUS RUN-TIME VALIDATION OF PROGRAM EXECUTION: A PRACTICAL APPROACH
    Publication number: 20140082329
    Abstract: Trustworthy systems require that code be validated as genuine. Most systems implement this requirement prior to execution by matching a cryptographic hash of the binary file against a reference hash value, leaving the code vulnerable to run time compromises, such as code injection, return and jump-oriented programming, and illegal linking of the code to compromised library functions. The Run-time Execution Validator (REV) validates, as the program executes, the control flow path and instructions executed along the control flow path. REV uses a signature cache integrated into the processor pipeline to perform live validation of executions, at basic block boundaries, and ensures that changes to the program state are not made by the instructions within a basic block until the control flow path into the basic block and the instructions within the basic block are both validated.
    Type: Application
    Filed: September 16, 2013
    Publication date: March 20, 2014
    Applicant: The Research Foundation of State University of New York
    Inventor: Kanad Ghose
  • APPARATUS AND METHOD FOR SYNTHESIZING INTERMEDIATE VIEW IMAGE, RECORDING MEDIUM THEREOF
    Publication number: 20140078136
    Abstract: Disclosed are an apparatus and method for synthesizing an intermediate view image and a recording medium thereof. The disclosed apparatus for synthesizing an intermediate view image may include: a probability information generating part configured to generate information related to a matching probability between a first image and a second image; and a synthesizing part configured to synthesize an intermediate view image by applying a weight according to the matching probability to the first image and second image. Certain embodiments of the invention provide the advantage of enabling enhanced image quality when synthesizing an intermediate view image without requiring post-processing operations such as for processing occlusions and for filling holes.
    Type: Application
    Filed: May 3, 2013
    Publication date: March 20, 2014
    Applicant: Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: Kwang-Hoon Sohn, Bum Sub Ham
  • MOLECULAR PROBES FOR DETECTING LIPID COMPOSITION
    Publication number: 20140079635
    Abstract: A method of detecting myelin in a subject includes administering to the subject a molecular probe that includes a fluorescent trans stilbene derivative and detecting the amount or distribution of the molecular probe in a tissue of interest of the subject.
    Type: Application
    Filed: April 29, 2013
    Publication date: March 20, 2014
    Applicant: Case Western Reserve University
    Inventor: Case Western Reserve University
  • NANOPARTICLES BASED FOR DERMAL AND SYSTEMIC DELIVERY OF DRUGS
    Publication number: 20140079642
    Abstract: The present invention relates to a poly(lactic glycolic) acid (PLGA) nanoparticle associated with therapeutic agents for a variety of therapeutic applications.
    Type: Application
    Filed: January 24, 2012
    Publication date: March 20, 2014
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem LTD
    Inventors: Simon Benita, Taher Nasser, Nour Karra, Amit Badihi
  • METHOD AND SYSTEM FOR REGISTERING IMAGES
    Publication number: 20140079338
    Abstract: A system for registering images includes an image registration unit. The image registration unit is configured to receive first image data for a first image in an N-dimensional space, receive second image data for a second image in the N-dimensional space, calculate a field of update vectors that maps the first image into a moving image, and map the first image into the moving image using the field of update vectors such that the moving image more closely matches the second image. The field of update vectors includes a plurality of N+M dimensional update vectors, each update vector having N spatial components and M extra components. N is a number greater than zero, and M is a number greater than zero. The M extra components of the plurality of update vectors identify portions of the first image that are assigned external values during the mapping the first image into the moving image.
    Type: Application
    Filed: May 14, 2012
    Publication date: March 20, 2014
    Applicant: The Johns Hopkins University
    Inventors: Jeffrey H. Siewerdsen, Sajendra Nithiananthan, Daniel J. Mirota
  • Smooth cordgrass name "LA11-101"
    Publication number: 20140082803
    Abstract: A new variety of smooth cordgrass identified as ‘LA11-101’ is disclosed as being genetically different from ‘Vermilion’, the only other smooth cordgrass variety for the northern Gulf of Mexico, and as having rapid establishment and growth in natural brackish and saline marsh environments, and excellent seed set and germination.
    Type: Application
    Filed: September 20, 2012
    Publication date: March 20, 2014
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Carrie Ann Knott, Michael David Materne, Herry Sutjahjo Utomo, Prasanta Kumar Subudhi, Niranjan Baisakh, Stephen Alan Harrison
  • Polypeptide Based Block Copolymer and the Process for the Preparation Thereof, and the Polymer Micelles Using the Same
    Publication number: 20140080922
    Abstract: A polypeptide based block copolymer having biodegradability due to peptidase, a process for the preparation thereof, and polymer micelles using the same are provided. The block copolymer is a block copolymer of a polyethylene glycol-based compound having properties such that the solubility for water is different depending on the pH, but cannot form micelles due to a self-assembly phenomenon; and a polyglutamic acid-based compound formed using an aminolysis reaction of glutamic acid and tertiary amine in which the end of one alkyl group is substituted with NH2, or using an aminolysis reaction of glutamic acid and triamine.
    Type: Application
    Filed: September 10, 2013
    Publication date: March 20, 2014
    Applicant: Research & Business Foundation Sungkyunkwan University
    Inventors: Doo Sung LEE, Yi LI, Bong Sup KIM
  • Deep Brain Magnetic Stimulator
    Publication number: 20140081072
    Abstract: A deep brain magnetic stimulator is disclosed that is placed within a vessel of the body to provide targeted location specific application of a magnetic field within the brain. The deep brain magnetic stimulator has a stimulation coil affixed to an expandable device core where the device core has a lumen to allow the passage of blood. A source of electrical energy is provided as well as related control circuitry to govern the activation of the stimulation coil and also govern such parameters as magnetic field strength, duration, waveform, and the like.
    Type: Application
    Filed: September 19, 2013
    Publication date: March 20, 2014
    Applicant: University of Rochester
    Inventors: Jason Haitao Huang, Samantha Dayawansa
  • NOVEL CONJUGATES OF POLYMERS HAVING A THERAPEUTICALLY ACTIVE AGENT AND AN ANGIOGENESIS TARGETING MOIETY ATTACHED THERETO AND USES THEREOF IN THE TREATMENT OF ANGIOGENESIS RELATED DISEASES
    Publication number: 20140079638
    Abstract: Conjugates of a polymer having attached thereto an angiogenesis targeting moiety and a therapeutically active agent such as an anti-cancer agent or anti-angiogenesis agent, and processes of preparing same are disclosed. Pharmaceutical compositions containing these conjugates and uses thereof in the treatment of angiogenesis-related medical conditions such as cancer and cancer metastases are also disclosed.
    Type: Application
    Filed: November 18, 2013
    Publication date: March 20, 2014
    Applicants: Fundacion de la Comunidad Valenciana Centro de Investigacion Principle Felipe, Ramot at Tel-Aviv University Ltd.
    Inventors: Ronit SATCHI-FAINARO, Maria Jesus Vicent Docon
  • Particle Aggregate, Manufacturing Method for Particle Aggregate, Fluorescence Enhancing Element, and Device Using Photochemical Reactions
    Publication number: 20140077132
    Abstract: Provided is a hollow particle aggregate formed by aggregating a plurality of self-organizable particles, wherein a metal core is modified by a surface modifier for a metal core comprising a first segment comprising an optionally branched fluorinated alkylene glycol group, an optionally branched fluorinated alkylene group, or an optionally branched fluorinated azaalkylene group; a second segment comprising at least one hydrophilic group and bonding to one of the ends of a main chain of the first segment; and a functional group that bonds directly or indirectly to the another end of the main chain of the first segment and is able to bond to the metal core.
    Type: Application
    Filed: February 22, 2012
    Publication date: March 20, 2014
    Applicant: National University Corporation,HokkaidoUniversity
    Inventors: Kuniharu Ijiro, Kenichi Niikura, Naoki Iyo, Takashi Nishio
  • Smooth cordgrass named 'LA11-103'
    Publication number: 20140082802
    Abstract: A new variety of smooth cordgrass identified as ‘LA11-103’ is disclosed as being genetically different from ‘Vermilion’, ‘LA11-101’, and ‘LA11-102’, as having rapid establishment and growth in natural brackish and saline marsh environments, and excellent seed set and germination.
    Type: Application
    Filed: September 20, 2012
    Publication date: March 20, 2014
    Applicant: Board of Supervisors of Louisiana State University and Agricultural and Mechanical College
    Inventors: Carrie Ann Knott, Michael David Materne, Herry Sutjahjo Utomo, Prasanta Kumar Subudhi, Niranjan Baisakh, Stephen Alan Harrison
  • INHIBITION OF BIOFILMS IN PLANTS WITH IMIDAZOLE DERIVATIVES
    Publication number: 20140079808
    Abstract: Disclosure is provided for methods of preventing, removing or inhibiting microbial biofilm formation or microbial infection in a plant or plant part thereof, including applying thereto a treatment effective amount of an active compound as described herein, or an agriculturally acceptable salt thereof. Methods of enhancing a microbicide (e.g., including a copper, antibiotic, bacteriophage, etc.) and/or plant defense activator are also provided, including applying an active compound as described herein. Compositions comprising an active compound as described herein in an agriculturally acceptable carrier are also provided, and in some embodiments the compositions further include a microbicide (e.g., including copper, antibiotic, bacteriophage, etc.) and/or plant defense activator.
    Type: Application
    Filed: November 25, 2013
    Publication date: March 20, 2014
    Applicant: North Carolina State University
    Inventors: Christian Melander, John Cavanagh, David Ritchie, Robert W. Huigens, III, T. Eric Ballard, Justin J. Richards, Thomas W. Lindsey, Jonathan S. Lindsey
  • METHOD FOR DETERMINING AXIAL DIRECTION OF BORE OF BONE FIXATOR
    Publication number: 20140079301
    Abstract: A method for determining an axial direction of a bore of a bone fixator includes the following steps: obtaining X-ray images of the bore, calculating perpendicular bisectors, determining spatial planes, and obtaining the axial direction of the bore. After X-ray images of the bore are taken from two X-ray source positions, two overlapping images of the bore are obtained for calculating two perpendicular bisectors therein respectively. Each perpendicular bisector and its corresponding X-ray source position define one spatial plane. The intersection of the two spatial planes defines the axial direction of the bore. Now that the axial direction of the bore can be derived from only two X-ray images of the bore taken during an orthopedic surgery, radiation exposure of the patient and of the medical personnel involved can be significantly reduced.
    Type: Application
    Filed: November 16, 2012
    Publication date: March 20, 2014
    Applicant: National Central University
    Inventors: Ching-Shiow TSENG, Pei-Chun Chen, Hung-Kang Wu
  • FORMING METHOD OF LAMINATED STRUCTURE BY INTERNAL OXIDATION
    Publication number: 20140079885
    Abstract: A forming method of a laminated structure by internal oxidation is provided. An alloy coating layer is formed. The alloy coating layer has a columnar grain structure and includes a first metal element and a second metal element, and the first metal element is oxidized more easily than the second metal element. Thereafter, a thermal oxidation treatment process is performed to the alloy coating layer, so as to form a plurality of oxide layers and a plurality of metal layers stacked alternately with each other from a surface portion of the alloy coating layer. A material of the oxide layers includes an oxide of the first metal element, and a material of the metal layers includes the second metal element.
    Type: Application
    Filed: November 19, 2013
    Publication date: March 20, 2014
    Applicant: National Taiwan Ocean University
    Inventor: Yung-I Chen