Patents Assigned to University
  • Patent number: 8634488
    Abstract: A channel condition information feedback method and apparatus are provided for a collaborative wireless communication network using a multiple input multiple output antenna system. The apparatus includes a downlink channel estimator that estimates channels of adjacent base stations, groups base stations from among the adjacent base stations that are capable of collaborative communication, and obtains a maximum singular vector to base stations belonged to a same group; and a vector selector which selects a weight vector most accurately representing the maximum singular vector and a complex variable most accurately representing the maximum singular vector in combination with the weight vector.
    Type: Grant
    Filed: July 27, 2010
    Date of Patent: January 21, 2014
    Assignees: Samsung Electronics Co., Ltd, Industry-Academic Cooperation Foundation, Yonsei University
    Inventors: In Ho Lee, Cheol Mun, Ju Ho Lee, Jin Kyu Han, Jong Gwan Yook
  • Patent number: 8634077
    Abstract: Methods and systems for optically characterizing a turbid sample are provided. A structured light beam is impinged on the sample. The sample includes an embedded region. A reflected light image of the structured light beam is detected from the sample. A measured reflectance image of the structured light beam for the sample is determined based on the reflected light image and a reflectance standard. The following parameters are determined: absorption coefficients ÿa, scattering coefficient ÿs and anisotropy factor g of the sample from the reflectance image. A size parameter of the embedded region is estimated based on the absorption coefficients ÿa, scattering coefficient ÿs and/or anisotropy factor g of the sample from the measured reflectance image.
    Type: Grant
    Filed: October 1, 2009
    Date of Patent: January 21, 2014
    Assignee: East Carolina University
    Inventors: Xin-Hua Hu, Cheng Chen
  • Patent number: 8634405
    Abstract: A system and method for synchronizing the phases and frequencies of devices in multi-user, wireless communications systems are provided. A primary beacon signal is transmitted by a destination node in a wireless communications network to a plurality of source nodes. Secondary beacon signals are also exchanged between the source nodes. Using the primary and secondary beacon signals, the nodes generate local phase and frequency estimates which are used to control local phases and frequencies of the source nodes. The source nodes then transmit common information to the destination at carrier frequencies based on the estimated local frequencies and phases, so that the phases and frequencies of the transmitted information are synchronized to facilitate coherent combining of the bandpass signals at the destination. Phase and frequency synchronization can be applied to wireless communications systems having any number of source nodes, and effects of Doppler shifts and moving platforms are accounted for.
    Type: Grant
    Filed: September 8, 2009
    Date of Patent: January 21, 2014
    Assignees: The Trustees of Princeton University, Worcester Polytechnic Institute
    Inventors: Donald Richard Brown, H. Vincent Poor, Boyang Zhang
  • Patent number: 8632723
    Abstract: Provided is a manufacturing method for preferentially-oriented oxide ceramics having a high degree of crystal orientation. The manufacturing method includes: obtaining slurry containing an oxide crystal B having magnetic anisotropy; applying a magnetic field to the oxide crystal B, and obtaining a compact of the oxide crystal B; and subjecting the compact to oxidation treatment to obtain preferentially-oriented oxide ceramics including a compact of an oxide crystal C having a crystal system that is different from a crystal system of one of a part and a whole of the oxide crystal B. By (1) reacting raw materials, (2) reducing the oxide crystal A, or (3) keeping the oxide crystal A at high temperature and quenching the oxide crystal A, the oxide crystal B is obtained to be used in the slurry.
    Type: Grant
    Filed: February 8, 2011
    Date of Patent: January 21, 2014
    Assignees: Canon Kabushiki Kaisha, University of Yamanashi
    Inventors: Takayuki Watanabe, Makoto Kubota, Jumpei Hayashi, Nobuhiro Kumada, Tomoaki Mochiduki
  • Patent number: 8632979
    Abstract: The present invention provides methods for determining a putative agent that treats or prevent obesity and/or obesity related diseases comprising contacting cells with the putative agent and measuring the activity and/or level of Maf1 and/or the activity and/or level of KIAA1875. The present invention also provides the agent identified by the methods herein and methods of treating or preventing obesity and/or obesity related diseases in a subject comprising administering to the subject a therapeutically effective amount of an agent that inhibits or downregulates Maf1 and/or activates or upregulates KIAA1875.
    Type: Grant
    Filed: November 17, 2011
    Date of Patent: January 21, 2014
    Assignees: Albert Einstein College of Medicine of Yeshiva University, University of Lausanne
    Inventors: Ian M. Willis, Nouria Hernandez, Wassim Hodroj
  • Patent number: 8632989
    Abstract: In one aspect, the present invention provides an isolated mutant insulin degrading enzyme (IDE) having an amino acid sequence that is at least 90% identical to SEQ ID NO:1 over its entire length and comprises at least one amino acid substitution at any of amino acid residues 332, 339, 341, 359, 360, 361, 374, 429, 609, 898, 899 or 901 of the sequence. The mutant IDE has a differential activity relative to that of wild-type IDE. Also provided is a polynucleotide encoding the polypeptide of the invention.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: January 21, 2014
    Assignee: University of Kentucky Research Foundation
    Inventors: David W. Rodgers, Louis B. Hersh, Nicholas Noinaj, Eun Suk Song
  • Patent number: 8631713
    Abstract: A measurement device capable of sensing presence of an obstacle within a vessel from outside the vessel in operating a linear body inserted in the vessel is provided. According to this measurement device, an easy-to-use measurement device capable of measuring compressive force in a direction of longitudinal axis applied to the linear body that has a sheath thicker than the linear body, such as a wire having a coil for embolizing an aneurysm attached at a tip end, without lowering measurement accuracy, can be provided. In addition, a length of a restraint portion is minimized, to achieve a smaller size of the measurement device. Moreover, the measurement device capable of measuring compressive force in the direction of longitudinal axis applied to the linear body regardless of magnitude of buckling load of the linear body can be provided, and the same measurement device is applicable to linear bodies of various materials, which leads to cost efficiency.
    Type: Grant
    Filed: August 30, 2007
    Date of Patent: January 21, 2014
    Assignees: National University Corporation Nagoya Institute of Technology, NTN Corporation
    Inventors: Hideo Fujimoto, Akihito Sano, Yoshitaka Nagano
  • Patent number: 8635711
    Abstract: A method for functionalizing cantilevers is provided that includes providing a holder having a plurality of channels each having a width for accepting a cantilever probe and a plurality of probes. A plurality of cantilever probes are fastened to the plurality of channels of the holder by the spring clips. The wells of a well plate are filled with a functionalization solution, wherein adjacent wells in the well plate are separated by a dimension that is substantially equal to a dimension separating adjacent channels of the plurality of channels. Each cantilever probe that is fastened within the plurality of channels of the holder is applied to the functionalization solution that is contained in the wells of the well plate.
    Type: Grant
    Filed: September 13, 2012
    Date of Patent: January 21, 2014
    Assignees: UT-Battelle, LLC, University of Tennessee Research Foundation
    Inventors: Barbara R. Evans, Ida Lee
  • Patent number: 8633304
    Abstract: The present invention provides an oligonucleotide derivative that enables to easily synthesize an oligonucleotide derivative chemically modified at the 3?-end with two moieties each having a benzene or pyridine structure with a few steps, an aromatic compound serving as a precursor for preparing the modification carrier for synthesizing oligonucleotide derivative, and the oligonucleotide derivative and the oligonucleotide construct using the same, that is chemically modified at the 3?-end with two moieties each having a benzene or pyridine structure, and has good permeability through a cell membrane and excellent nuclease resistance. The modification carrier for synthesizing oligonucleotide derivative, comprising a unit and a carrier carrying the unit directly or via a linker, wherein the unit is represented by the formula (a): wherein, R1 to R6 each independently represent hydrogen or a substituent other than hydrogen; Z1 and Z2 each independently represent CH or nitrogen; and X represents oxygen or sulfur.
    Type: Grant
    Filed: December 8, 2010
    Date of Patent: January 21, 2014
    Assignee: Gifu University
    Inventors: Yukio Kitade, Yoshiaki Kitamura
  • Patent number: 8632914
    Abstract: The present disclosure relates to certain new and known triazolium and/or imidazolium salts and to their therapeutic use, for example in methods of treating or preventing an infection by a Plasmodium or Babesia parasite in a subject in need thereof. The triazolium and imidazolium salts are compounds of the Formula (I) or (II): wherein R1-R4, R1?-R3?, R8-R11, X, X?, X?, Y, Y? and Y? are as defined in the disclosure.
    Type: Grant
    Filed: September 4, 2009
    Date of Patent: January 21, 2014
    Assignee: University Health Network
    Inventors: Ian E. Crandall, Walter A. Szarek, Jason Z. Vlahakis
  • Patent number: 8633308
    Abstract: Described herein are compounds and methods that prevent the viral infection of cells. The compounds and methods described herein minimize viral resistance and maximize the number of targeted viruses. Additionally, the compounds and methods minimize the toxicity toward uninfected cells.
    Type: Grant
    Filed: February 27, 2008
    Date of Patent: January 21, 2014
    Assignee: The Governors of The University of Alberta
    Inventors: Luis M. Schang, Mireilli R. St. Vincent, Alexey V. Ustinov
  • Patent number: 8632773
    Abstract: The present invention relates to a population of antibodies enriched from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. Furthermore, the present invention relates to a method of enriching a population of antibodies from an antibody preparation, wherein the enriched population of antibodies has an altered amount of sialylation in the Fab region of the antibodies as compared to the antibody preparation prior to enrichment. The present invention also relates to the population of antibodies of the invention for use in medicine, a pharmaceutical composition comprising the populations of antibodies of the invention and the use of the population of antibodies of the invention in the prevention and/or treatment of atherosclerosis, cancer and infections such as bacterial, viral or fungal infections.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: January 21, 2014
    Assignees: CSL Behring AG, University of Washington
    Inventors: Fabian Käsermann, Monika Rüegsegger, Sylvia Miescher, Keith Elkon
  • Patent number: 8633221
    Abstract: A method of enhancing the activity of lysosomal ?-Galactosidase A (?-Gal A) in mammalian cells and for treatment of Fabry disease by administration of 1-deoxy-galactonojirimycin and related compounds.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: January 21, 2014
    Assignee: Mount Sinai School of Medicine of New York University
    Inventors: Jian-Qiang Fan, Satoshi Ishii
  • Patent number: 8632717
    Abstract: A method of nanoimprinting a piezoelectric polymeric material includes: heating a surface of the piezoelectric polymeric material to an imprinting temperature greater than (Tc?25)° C. and less than Tc, in which Tc is the Curie temperature of the piezoelectric polymeric material; and pressing the heated surface of the piezoelectric polymeric material using a nanoimprinting template having a nanopillar structure so as to form the piezoelectric polymeric material with high aspect ratio nanopillars.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: January 21, 2014
    Assignee: National Tsing Hua University
    Inventors: Chien-Chong Hong, Sheng-Yuan Huang
  • Patent number: 8633179
    Abstract: The present invention relates to methods and compositions for preventing and/or treating various conditions in a patient, including for example, T-cell lymphoblastic leukemia and lymphoma as well as neurodegenerative diseases, such as for example, Alzheimer's disease. In one preferred embodiment of the invention, such methods include providing a patient with an effective amount of a combination of a NOTCH-1 inhibitor and glucocorticoid. The present invention further encompasses methods for increasing the efficacy of, and mitigating resistance to, glucocorticoids in the treatment of T-cell lymphoblastic leukemia and lymphoma, which generally include providing a patient with an effective amount of one or more NOTCH-1 inhibitors.
    Type: Grant
    Filed: March 13, 2008
    Date of Patent: January 21, 2014
    Assignee: The Trustees of Columbia University in the City of New York
    Inventors: Adolfo A. Ferrando, Pedro J. Real
  • Patent number: 8634233
    Abstract: Systems and methods that enable direct communications between magnetic tunnel junctions are provided. In one embodiment, a device includes multiple input magnetic tunnel junctions and an output magnetic tunnel junction. The multiple input magnetic tunnel junctions are connected in parallel, and the output magnetic tunnel junction is connected in series to the input magnetic tunnel junctions. In another embodiment, a device includes a first magnetic tunnel junction, a second magnetic tunnel junction, and a nano-magnetic channel. Each of the first and the second magnetic tunnel junctions has a free layer, a nonmagnetic layer, and a fixed layer. The nano-magnetic channel connects the free layer of the first magnetic tunnel junction to the free layer of the second magnetic tunnel junction.
    Type: Grant
    Filed: May 18, 2012
    Date of Patent: January 21, 2014
    Assignee: Regents of the University of Minnesota
    Inventors: David J. Lilja, Jian-Ping Wang, Andrew P. Lyle, Shruti R. Patil, Jonathan D. Harms, Xiaofeng Yao
  • Patent number: 8634074
    Abstract: Methods and systems for measuring particles within a flow are provided. An aircraft transports a high volume sample rate holographic measurement instrument through a particle-containing volume of interest along a reference axis X (time). As the instrument moves relative to the volume of interest, the holographic measurement instrument transmits a collimated light beam across the volume of interest along an optical axis Z. The light beam interacts with particles contained within the volume of interest, and a high-speed, one-dimensional detector array detects incident light reflecting patterns of light intensity levels that are associated with the interaction between the light beam and the particles.
    Type: Grant
    Filed: April 15, 2011
    Date of Patent: January 21, 2014
    Assignee: University Corporation for Atmospheric Research
    Inventor: Jacob Fugal
  • Patent number: 8633465
    Abstract: The present invention discloses a multilevel resistive memory having large storage capacity, which belongs to a field of a fabrication technology of a resistive memory. The resistive memory includes an top electrode and a bottom electrode, and a combination of a plurality of switching layers and defective layers interposed between the top electrode and the bottom electrode, wherein, the top electrode and the bottom electrode are respectively contacted with a switching layer (a film such as Ta2O5, TiO2, HfO2), and the defective layers (metal film such as Ti, Au, Ag) are interposed between the switching layers. By using the present invention, a storage capacity of a resistive memory can be increased.
    Type: Grant
    Filed: February 8, 2012
    Date of Patent: January 21, 2014
    Assignee: Peking University
    Inventors: Ru Huang, Gengyu Yang, Yimao Cai, Yu Tang, Lijie Zhang, Yue Pan, Shenghu Tan, Yinglong Huang
  • Patent number: 8633033
    Abstract: A method and apparatus of determining the condition of a bulk tissue sample, by: positioning a bulk tissue sample between a pair of induction coils (or antennae); passing a spectrum of alternating current (or voltage) through a first of the induction coils (or antennae); measuring spectrum of alternating current (or voltage) produced in the second of the induction coils (or antennae); and comparing the phase shift between the spectrum of alternating currents (or voltages) in the first and second induction coils (or antennae), thereby determining the condition of the bulk tissue sample.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: January 21, 2014
    Assignee: The Regents of the University of California
    Inventors: Boris Rubinsky, Cesar A. Gonzalez
  • Patent number: RE44711
    Abstract: An optical image-driven light induced dielectrophoresis (DEP) apparatus and method are described which provide for the manipulation of particles or cells with a diameter on the order of 100 ?m or less. The apparatus is referred to as optoelectric tweezers (OET) and provides a number of advantages over conventional optical tweezers, in particular the ability to perform operations in parallel and over a large area without damage to living cells. The OET device generally comprises a planar liquid-filled structure having one or more portions which are photoconductive to convert incoming light to a change in the electric field pattern. The light patterns are dynamically generated to provide a number of manipulation structures that can manipulate single particles and cells or group of particles/cells. The OET preferably includes a microscopic imaging means to provide feedback for the optical manipulation, such as detecting position and characteristics wherein the light patterns are modulated accordingly.
    Type: Grant
    Filed: November 1, 2011
    Date of Patent: January 21, 2014
    Assignee: The Regents of the University of California
    Inventors: Ming Chiang Wu, Pei-Yu Chiou, Aaron T. Ohta