Patents Assigned to University
  • Patent number: 8214012
    Abstract: Critical needs for MRI patient instruction, testing, comfort, motion control, and speech communication are provided for better imaging which leads to more effective medical care. An MRI Digital Video Projection System is disclosed which provides better quality display to the patient to better inform, instruct, test, and comfort the patient plus the potential to stimulate the brain with microsecond onset times to better diagnose brain function. An MRI Motion Tracker and Patient Augmented Visual Feedback System enables monitoring patient body part motion, providing real time feedback to the patient and/or technician to substantially improve diagnostic yield of scanning sessions, particularly for children and mentally challenged individuals. An MR Forward Predictive Noise Canceling Microphone System removes the intense MRI acoustic noise improving patient communication, patient safety and enabling coding of speech output. These systems can be used individually but maximum benefit is from providing all three.
    Type: Grant
    Filed: June 17, 2005
    Date of Patent: July 3, 2012
    Assignees: Psychology Software Tools, Inc., University of Pittsburgh
    Inventors: Anthony P. Zuccolotto, Walter Schneider, Leroy K. Basler
  • Patent number: 8214196
    Abstract: A statistical translation model (TM) may receive a parse tree in a source language as an input and separately output a string in a target language. The TM may perform channel operations on the parse tree using model parameters stored in probability tables. The channel operations may include reordering child nodes, inserting extra words at each node (e.g., NULL words) translating leaf words, and reading off leaf words to generate the string in the target language. The TM may assign a translation probability to the string in the target language.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: July 3, 2012
    Assignee: University of Southern California
    Inventors: Kenji Yamada, Kevin Knight
  • Patent number: 8211020
    Abstract: A device for combining tomographic images with human vision using a half-silvered mirror to merge the visual outer surface of an object (or a robotic mock effector) with a simultaneous reflection of a tomographic image from the interior of the object. The device maybe used with various types of image modalities including ultrasound, CT, and MRI. The image capture device and the display may be enclosed in a sterile container (e.g., a probe bag) and a mirror and mirror housing may be separately attachable to the image capture device and display. In these embodiments, the mirror may be disposable and the sterility of the overall imaging device is maintained.
    Type: Grant
    Filed: February 28, 2008
    Date of Patent: July 3, 2012
    Assignee: University of Pittsburgh—Of The Commonwealth System of Higher Education
    Inventors: George DeWitt Stetten, William David Weiser, David C. Wang, John M. Galeotti, Damion M. Shelton
  • Patent number: 8211432
    Abstract: Disclosed are antibodies that block the binding of fibronectin protein to fibronectin. Also disclosed are site specifically-mutated and truncated peptide epitopes derived from the fnbA and fnbB genes of Staphylococcus aureus, the fnbA and fnbB genes of Streptococcus dysgalactiae, and the sfb gene of Streptococcus pyogenes, and nucleic acid segments encoding these peptides and epitopes. The anti-(fibronectin binding site) antibodies, peptides and epitopes that give rise to antibodies that block the binding of fibronectin binding proteins to fibronectin, and DNA segments encoding these proteins and are of use in various screening, diagnostic and therapeutic applications including active and passive immunization and methods for the prevention of streptococcal and staphylococcal colonization in animals or humans. These. DNA segments and the peptides derived therefrom are proposed to be of use directly in the preparation of vaccines and also for use as carrier proteins in vaccine formulations.
    Type: Grant
    Filed: October 31, 2006
    Date of Patent: July 3, 2012
    Assignees: University of Manitoba, Universita' Degli Studi di Pavia, Texas A&M University System
    Inventors: Magnus Höök, Joseph M. Patti, Karen L. House-Pompeo, Pietro Speziale, Danny Joh, Martin J. McGavin
  • Patent number: 8211646
    Abstract: Genomic analysis of ovarian cancers demonstrated a regional chromosomal increase in expression and gene duplication. TGF-? stimulation indicated a link between SnoN RNA and TGF-?. In TIOSE, SnoN protein levels were reduced 15 min post TGF-?-stimulation, likely by proteosome-mediated degradation. SnoN inhibition decreased cell growth between 20 and 50% concurrent with increased p21 levels. Stable expression of SnoN led to growth arrest through induction of senescence. Collectively, these results implicate SnoN levels in multiple roles during ovarian carcinogenesis: promoting cellular proliferation in ovarian cancer cells and as a positive mediator of cell cycle arrest and senescence in non-transformed ovarian epithelial cells.
    Type: Grant
    Filed: November 16, 2009
    Date of Patent: July 3, 2012
    Assignee: University of South Florida
    Inventors: Meera Nanjundan, Gordon Mills, Dawn Smith
  • Patent number: 8212056
    Abstract: The present invention relates to indolyl phosphine ligands, and methods of making such ligands utilizing phenyl hydrazines and aryl ketones as the starting material. The present invention further includes uses of the ligands in the synthesis of pharmaceuticals, materials, and agriculture.
    Type: Grant
    Filed: June 30, 2008
    Date of Patent: July 3, 2012
    Assignee: The Hong Kong Polytechnic University
    Inventors: Fuk Yee Kwong, Chau Ming So
  • Patent number: 8211214
    Abstract: The present invention is directed toward a method for reducing pattern distortions in imprinting layers by reducing gas pockets present in a layer of viscous liquid deposited on a substrate. To that end, the method includes varying a transport of the gases disposed proximate to the viscous liquid. Specifically, the atmosphere proximate to the substrate wherein a pattern is to be recorded is saturated with gases that are either highly soluble, highly diffusive, or both with respect to either the viscous liquid, the substrate, the template, or a combination thereof. Additionally, or in lieu of saturating the atmosphere, the pressure of the atmosphere may be reduced.
    Type: Grant
    Filed: February 5, 2008
    Date of Patent: July 3, 2012
    Assignees: Molecular Imprints, Inc., Board of Regents, The University of Texas
    Inventors: Frank Y. Xu, Niyaz Khusnatdinov
  • Patent number: 8211557
    Abstract: A magnetic microstructure comprising (i) a magnetic storage layer having a magnetic easy axis perpendicular to a film plane of the storage magnetic layer; (ii) a magnetic assist layer having a magnetic easy axis in the film plane; and (iii) a phase transition interlayer between the magnetic storage layer and the magnetic assist layer. The phase transition layer comprises a material, such as FeRh, that switches from antiferromagnetic at ambient to ferromagnetic at a transition temperature that is greater than ambient, but below the Curie temperature. When the phase transition interlayer is in antiferromagnetic phase, there exists little magnetic coupling between the storage and assist layers. When the interlayer changes to ferromagnetic phase, the interlayer couples the magnetic moments of the storage and assist layer ferromagnetically.
    Type: Grant
    Filed: January 31, 2007
    Date of Patent: July 3, 2012
    Assignee: Carnegie Mellon University
    Inventors: Jian-Gang Zhu, David E. Laughlin
  • Patent number: 8212643
    Abstract: A bobbin is designed to reduce the voltage stress between the winding layers of the inner winding of an inductive electronic component. A partition transversely extends from the winding surface of the bobbin to divide the winding surface into separated winding surface sections. A partition defines a passage for winding the coil from one winding surface section to the other winding surface section. Passage openings are positioned on each winding surface section relative the winding surface so that a portion of the partition is always between the passage opening and the oppositely disposed winding surface section.
    Type: Grant
    Filed: April 22, 2009
    Date of Patent: July 3, 2012
    Assignee: Universal Lighting Technologies, Inc.
    Inventors: Donald Folker, Mike LeBlanc
  • Patent number: 8211883
    Abstract: The invention relates to topical pharmaceutical compositions comprising a phthalocyanine, wherein a diamagnetic metal ion moiety is either coordinated or covalently bound to the phthalocyanine core. The invention also relates to methods for destroying cancer tissue, precancerous cells, photo-aged cells, damaged cells, or otherwise pathologic cells, or activated cells, such as lymphocytes or other cells of the immune system, or activated or inflamed tissue cells comprising topically administering to the cancer tissue or surrounding tissue an effective amount of a phthalocyanine composition.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: July 3, 2012
    Assignee: Case Western Reserve University
    Inventors: Kevin D. Cooper, Nancy L. Oleinick, Malcolm E. Kenney, Thomas S. McCormick, Jeffrey C. Berlin, Elma D. Baron
  • Patent number: 8211700
    Abstract: This invention relates to methods of inducing differential stress resistance in a subject with cancer by starving the subject for a short term, administering a cell growth inhibitor to the subject, or reducing the caloric or glucose intake by the subject. The induced differential stress resistance results in improved resistance to cytotoxicity in normal cells, which, in turn, reduces cytotoxic side-effects due to chemotherapy, as well as improved effectiveness of chemotherapeutic agents.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: July 3, 2012
    Assignee: University of Southern California
    Inventor: Valter Longo
  • Patent number: 8214133
    Abstract: An apparatus includes a parallel computation unit including an input port and an output port and a one-dimensional computational fluid dynamics model. The input port is configured to sample at a time t1 a boundary condition signal for the one-dimensional computational fluid dynamics model and the output port is configured to provide an output signal before the boundary condition signal is sampled at a time t2.
    Type: Grant
    Filed: August 1, 2011
    Date of Patent: July 3, 2012
    Assignee: Colorado State University Research Foundation
    Inventor: Matthew Viele
  • Patent number: 8213695
    Abstract: The present invention provides devices for screening the skin of an individual in real time using a region-fusion based segmentation with narrow band graph partitioning algorithm to analyze and classify a region of interest of the skin as benign or malignant. Also, provided is a method for screening the skin of an individual using the devices described herein. In addition the present invention provides a digital processor-implemented system for classifying a region of interest on the skin and a processor readable medium having processor-executable instructions to perform skin cancer detection.
    Type: Grant
    Filed: March 7, 2008
    Date of Patent: July 3, 2012
    Assignees: University of Houston, Texas Instruments Incorporated
    Inventors: George Zouridakis, Xiaojing Yuan, Ji Chen, Eric Stotzer, Yanmin Wu
  • Patent number: 8210792
    Abstract: A method and system for harvesting wind energy. The system may include a wind turbine disposed subjacent to a roof assembly of building. A plurality of conduits are adjacent to and extending below the wind turbine, wherein each of the plurality of conduits defines a first portion and a second portion, wherein the first portion defines a larger cross-sectional area than the second portion.
    Type: Grant
    Filed: June 10, 2010
    Date of Patent: July 3, 2012
    Assignee: University of Miami
    Inventor: Alexander B. Suma
  • Patent number: 8211933
    Abstract: In one aspect, the invention relates to compounds which are useful as as inhibitors of glycine type 1 transporter (GlyT1) activity; synthetic methods for making the compounds; pharmaceutical compositions comprising the compounds; and methods of treating disorders associated with glycine type 1 transporter (GlyT1) activity using the compounds and compositions. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
    Type: Grant
    Filed: December 11, 2009
    Date of Patent: July 3, 2012
    Assignee: Vanderbilt University
    Inventors: Craig W. Lindsley, P. Jeffrey Conn, Richard Williams, Douglas J. Sheffler
  • Patent number: 8210124
    Abstract: A method of artificially rearing lobster larvae, in which lobster larvae of the Palinuridae and Scyllaridae families are guided toward jellyfish so that the lobster larvae parasitize the jellyfish and grow on the host jellyfish. An apparatus for rearing lobster larvae wherein a symbiotic feeding tank (1), in which the larvae are reared in the state of being parasitic on the jellyfish, and a jellyfish rearing tank (2) are connected together via a pipe (3), through which water and the jellyfish are supplied from the jellyfish rearing tank (2) to the symbiotic feeding tank (1), and the pipe (3) is provided with a switching valve (7).
    Type: Grant
    Filed: October 20, 2008
    Date of Patent: July 3, 2012
    Assignees: National University Corporation Tokyo University, Tokyo University of Marine Science and Technology
    Inventors: Yuji Tanaka, Yoshioki Oozeki
  • Patent number: 8213417
    Abstract: A system for communication between a mobile node and a communications network is provided for use with a communications network having one or more communications network nodes that define a foreign agents and that communicate with the mobile node in a predefined region. The system includes a ghost-foreign agent that advertises a foreign agent so that the mobile node is aware of the foreign agent when the mobile node is located outside the predefined region. The system further includes a ghost-mobile node that signals the foreign agent in response to the foreign agent advertising and based upon a predicted future state of the mobile node.
    Type: Grant
    Filed: March 5, 2010
    Date of Patent: July 3, 2012
    Assignee: University of Florida Research Foundation, Inc.
    Inventors: Edwin A. Hernandez-Mondragon, Abdelsalam A. Helal
  • Patent number: 8212561
    Abstract: Referenceless techniques for flow imaging are described that exploit a refocusing property of balanced steady state free precession (“SSFP”) magnetic resonance imaging (“MRI”), and achieve up to approximately a 50% reduction in total scan time. With the echo time set to one half of the sequence repetition time (TE=TR/2), non-flow-related image phase tends to vary smoothly across the field-of-view, and can be estimated from static tissue regions to produce a phase reference for nearby voxels containing flowing blood. These approaches produce accurate in vivo one-dimensional velocity estimates in half the scan time compared with conventional balanced SSFP phase-contrast methods. The feasibility of referenceless time-resolved 3D flow imaging (called “7D” flow) is demonstrated for a carotid bifurcation application from just three acquisitions. Related systems are also described. Other attributes such as blood acceleration can also be imaged with such techniques.
    Type: Grant
    Filed: October 20, 2009
    Date of Patent: July 3, 2012
    Assignee: University of Southern California
    Inventors: Jon-Fredrik Nielsen, Krishna S. Nayak
  • Patent number: 8213213
    Abstract: A reference current generator for a resistance type memory and a method thereof is disclosed. The reference current generator comprises N parallel circuit sets. Each of the N parallel circuit sets is formed with at least one first reference element and second reference elements connected in parallel. The number of the first reference elements plus the number of the second reference elements is N. The resistance value of first reference elements (a first resistance value) is not equal to the resistance value of the second reference elements (a second resistance value). An equivalent resistance provided with a equivalent resistance value between the first and second resistance value is formed by connecting the N parallel circuit sets in series between an input terminal and output terminal. A reference current is outputted from the output terminal by applying an operation voltage to the input terminal.
    Type: Grant
    Filed: November 9, 2009
    Date of Patent: July 3, 2012
    Assignee: National Tsing Hua University
    Inventors: Meng-Fan Chang, Ku-Feng Lin, Pi-Feng Chiu
  • Patent number: 8212090
    Abstract: The methods of the disclosure may be used for the fluorination of organic compounds, and in particular aryl organic compounds other than just benzyl halogens. It is within the scope of the present disclosure, for organic compounds comprising an electrophilic carbon atom and a halogen leaving group to be fluorinated by the methods of the disclosure. One aspect of the disclosure provides methods of introducing a fluorine atom onto an electrophilic carbon atom, comprising mixing an insoluble basic silver salt, an organic molecule containing a leaving group, an aqueous solution of hydrofluoric acid, and a polar solvent:water composition; incubating said mixture at a temperature of about 20° C. to about 35° C., thereby obtaining a fluorinated organic product.
    Type: Grant
    Filed: December 10, 2009
    Date of Patent: July 3, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Christopher C. Caires, Samira Guccione