Patents Assigned to University
  • Publication number: 20120146869
    Abstract: A planar ultrawideband modular antenna for connection to a feed network. The antenna has a ground plane, and an array of antenna elements spaced from the ground plane, each antenna element comprising a pair of arms. A first fed arm is electrically coupled to the feed network. The grounded arm is directly electrically coupled to the ground plane. There are one or more conductors such as conductive vias electrically connecting the fed arm to the ground plane, and optionally there are one or more additional conductors electrically connecting the grounded arm to the ground plane.
    Type: Application
    Filed: August 2, 2010
    Publication date: June 14, 2012
    Applicant: University of Massachusetts
    Inventors: Steven S. Holland, Marinos N. Vouvakis
  • Publication number: 20120149738
    Abstract: Pyridine compounds effective in modulation STAT3 and/or STAT5 activation are provided that are useful in the prevention and treatment of proliferative disease and conditions including cancer, inflammation and proliferative skin disorders.
    Type: Application
    Filed: February 21, 2012
    Publication date: June 14, 2012
    Applicant: Board of Regents, The University of Texas System
    Inventors: Waldemar Priebe, Stanislaw Skora, Timothy Madden, Izabela Fokt, Charles Conrad
  • Publication number: 20120149686
    Abstract: The invention is directed to a compound represented by the following structural formula and pharmaceutically acceptable salts thereof: Compounds represented by this structural formula are kinase inhibitors and are therefore disclosed herein for the treatment of cancer. Definitions for the variables in the structural formula are provided herein.
    Type: Application
    Filed: April 6, 2010
    Publication date: June 14, 2012
    Applicant: University Health Networks
    Inventors: Peter B. Sampson, Yong liu, Sze-Wan Le, Brian T. Forrest, Heinz W. Pauls, Louise G. Edwards, Miklos Feher, Narendra Kumar B. Patel, Guohua Pan
  • Publication number: 20120149963
    Abstract: The subject invention provides a potentially economically viable process for the destruction of small to large quantities of sulfur and nitrogen mustards and lewisite, their homologous/analogues, and similar chemical warfare agents at ambient conditions without producing any toxic by-products. The process uses the superoxide ion that is either electrochemically generated by the reduction of oxygen in ionic liquids or chemically by dissolving Group 1 (alkali metals) or Group 2 (alkaline earth metals) superoxides, e.g. potassium superoxide, in ionic liquids.
    Type: Application
    Filed: March 26, 2008
    Publication date: June 14, 2012
    Applicant: King Saud University
    Inventors: Inas Muen Al Nashef, Saeed M. Al Zahrani
  • Publication number: 20120150031
    Abstract: Provided herein are systems, methods, and compositions for the thermal imaging of cells with nanoparticles.
    Type: Application
    Filed: December 6, 2011
    Publication date: June 14, 2012
    Applicants: Board of Regents, The Texas University System, Volcano Corporation
    Inventors: Paul Castella, Jihoon Kim
  • Publication number: 20120148630
    Abstract: Provided are methods and kits for safe and effective therapy that can be administered early after a heart attack in order to prevent progressive heart dilatation and resultant loss of function. The therapy includes the administration of particulate compositions to a region comprising an infarct or a portion thereof.
    Type: Application
    Filed: September 19, 2008
    Publication date: June 14, 2012
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Robert C. Gorman, Joseph H. Gorman, Liam P. Ryan
  • Publication number: 20120148716
    Abstract: Antimicrobial compositions are provided comprising a pharmaceutically acceptable organic acid and a pharmaceutically acceptable surfactant. This synergistic combination allows compositions to be formulated at low concentrations that have efficacy in reducing bacterial counts by greater than 3 log within 5 minutes of contact while preserving the organoleptic properties of treated foods, including fresh produce. Also provided are methods for the use of the compositions to reduce the microbial load on the surfaces of foodstuffs, processed food products, and the hard surfaces of food preparation machinery, tools, benches, and the like.
    Type: Application
    Filed: February 1, 2012
    Publication date: June 14, 2012
    Applicant: University of Georgia Research Foundation
    Inventors: Michael P. Doyle, Tong Zhao
  • Publication number: 20120148537
    Abstract: A method is provided to functionally select cells with enhanced characteristics relevant to cell engraftment, including both spontaneous migration and directional migration towards specific chemo-attractants. The cells are preferably undifferentiated cells, such as mesenchymal stem cells. The method involves entrapping or encapsulating the cells in a biomaterial barrier, optionally inducing cell migration, and selecting cells that migrated through the barrier. The cells selected by this method have better migratory activities and enhanced in vivo engraftment to injured tissues when they are supplemented systemically.
    Type: Application
    Filed: June 14, 2011
    Publication date: June 14, 2012
    Applicant: The University of Hong Kong
    Inventors: Barbara Pui Chan, Hoi Ling Wong, Mei Yi Wong, Godfrey Chi-Fung Chan, Zhen Fan Yang
  • Patent number: 8197911
    Abstract: An object of complex three-dimensional configuration, such as an automotive vehicle body, is coated with a combination of a coating formulation and a photoactivated mixture containing active centers that have been produced prior to application. The two liquids can be intimately mixed prior to application to the object, or the coating formulation can be applied prior to the application of the photoactivated mixture. The coating formulation is cured by the active centers that have been produced prior to application.
    Type: Grant
    Filed: June 8, 2007
    Date of Patent: June 12, 2012
    Assignees: Toyota Motor Engineering & Manufacturing North America, Inc., University of Iowa Research Foundation
    Inventors: Cynthia G. Templeman, Eric M. Leonard, Beth Ann Ficek, Alec B. Scranton
  • Patent number: 8198368
    Abstract: Cleavable, disulfide-coupled block copolymers as can be used in the preparation of nanoporous thin films, micellar configurations and related structures.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: June 12, 2012
    Assignee: University of Massachusetts
    Inventors: Sankaran Thayumanavan, Akamol Klaikherd, Suhrit Ghosh
  • Patent number: 8198039
    Abstract: Provided herein are biosensors that comprise a biological signal source linked to a substrate by a peptide nucleic acid spacer and methods of use of the biosensor. In one embodiment, the biosensor is used to detect prostate-specific antigen.
    Type: Grant
    Filed: September 4, 2008
    Date of Patent: June 12, 2012
    Assignee: University of Pittsburgh—Of the Commonwealth System of Higher Education
    Inventors: Haibin Shi, Joanne I. Yeh
  • Patent number: 8198048
    Abstract: The present invention provides isolated nucleic acid and amino acid sequences of sweet taste receptors comprising two heterologous G-protein coupled receptor polypeptides from the T1R family of sensory G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of sweet taste receptors.
    Type: Grant
    Filed: March 10, 2010
    Date of Patent: June 12, 2012
    Assignees: The Regents of the University of California, The United States of America as represented by the Department of Health and Human Services
    Inventors: Charles S. Zuker, Nicholas J. P. Ryba, Gregory A. Nelson, Mark A. Hoon, Jayaram Chandrashekar, Yifeng Zhang
  • Patent number: 8198325
    Abstract: Disclosed are unsaturated alkyl esters of 5-aminovulinic acid of the following chemical formula 1, or pharmaceutically acceptable salts thereof, a method for preparing the same, and uses thereof. [Chemical Formula I] NH2—CH2—CO—CH2—CH2—CO—O—R wherein, R is a group selected from a group consisting of 2-propenyl, 3-butenyl, 4-pentenyl, 5-hexenyl, cis-2-pentenyl, cis-3-hexenyl, cis-4-hexenyl, and trans-2-hexenyl. Also, a pharmaceutical composition comprising the unsaturated alkyl ester of 5-aminovulinic acid or a salt thereof as an active ingredient is provided. This pharmaceutical composition is easily absorbed transdermally and is of low cytotoxicity. Featuring no amino-protecting processes, the method guarantees high production yields.
    Type: Grant
    Filed: June 28, 2007
    Date of Patent: June 12, 2012
    Assignee: Industry Foundation of Chonnam National University
    Inventors: Jonghoon Oh, Jee-Bum Lee, Hyoung-Ryun Park
  • Patent number: 8198436
    Abstract: A chromogenic oxazine compound for the colorimetric detection of cyanide was designed. Indeed, the [1,3]oxazine ring of our compound opens to form a phenolate chromophore in response to cyanide. The heterocyclic com-pound may be comprised of fused benzooxazine and indoline rings: wherein R1 is an alkyl (e.g., methyl, ethyl, propyl, isopropyl, butyl, isobutyl), a substituted alkyl, a cycloalkyl (e.g., cyclopentyl, cyclohexyl), a substituted cycloalkyl, an aryl (e.g., phenyl), or a substituted aryl and R2 is a chromophore (e.g., nitroso, nitro, azo dyes). This quantitative chromogenic transformation permits the detection of micromolar concentrations of cyanide in water. Furthermore, our chromogenic oxazine is insensitive to the presence of large concentrations of fluoride, chloride, bromide or iodide anions, which are generally the principal interferents in the colorimetric detection of cyanide.
    Type: Grant
    Filed: September 1, 2006
    Date of Patent: June 12, 2012
    Assignee: The University of Miami
    Inventors: Francisco M. Raymo, Massimiliano Tomasulo
  • Patent number: 8198447
    Abstract: A fused tricyclic compound having aldose reductase inhibitory activity and shown by the following formula, wherein R1 represents 1 to 3 atoms or substituents selected from a hydrogen atom, a halogen atom, a substituted or unsubstituted alkyl, cycloalkyl, alkylene, or alkoxy group, and a protected or unprotected hydroxyl or carboxyl group, R2 represents a protected or unprotected carboxyl group, R3 represents 1 or 2 atoms or substituents selected from a hydrogen atom, a halogen atom, an oxo group, a substituted or unsubstituted alkyl or alkoxy group, and a protected or unprotected carboxyl group, A represents an alkylene group, and B represents an oxygen atom, a sulfur atom, or a group shown by the following formula, wherein R4 represents an alkyl or aryl group substituted by an aryl, cycloalkyl, or heterocyclic group, and X represents an oxygen atom or a sulfur atom, provided that, when B represents a group shown by the following formula: wherein R4 represents an alkyl or aryl group substituted
    Type: Grant
    Filed: February 11, 2010
    Date of Patent: June 12, 2012
    Assignee: National University Corporation University of Toyama
    Inventors: Naoki Toyooka, Atsushi Kato, Isao Adachi
  • Patent number: 8197809
    Abstract: The present invention relates to a CD9-specific human antibody, more precisely a CD9-specific human antibody composed of human derived CD9-specific complementarity determining region (CDR) and framework region (FR). The human antibody of the present invention recognizes CD9 extracellular loop 2 domain (CD9-ECL2) as an epitope and thereby strongly binding thereto. The human antibody of the present invention also has CD9 antigen neutralizing effect and at the same time inhibiting effect on tumor cell lines. Therefore, it can be effectively used for the prevention and treatment of cancer overexpressing CD9.
    Type: Grant
    Filed: November 24, 2008
    Date of Patent: June 12, 2012
    Assignees: Korea Research Institute of Bioscience and Biotechnology, Sungkyunkwan University Foundation for Corporate Collaboration
    Inventors: Young Woo Park, So-Young Choi, Ji Hyun Park, Jung Yu, Eun-Jung Song, Sungsub Kim, Myeoung Hee Jang, Mi-Ju Park, Je-Ho Lee, Jae Ryoung Hwang
  • Patent number: 8198655
    Abstract: An integrated circuit comprising both memory and logic wherein at least one layer of the integrated circuit is fabricated using a common grating pattern for both memory and logic is described. In one embodiment, the integrated circuit comprises a substrate, an active layer, and a gate material layer such as a polysilicon layer, and the active layer, the gate material layer, or both the active layer and the gate material layer are formed using a common grating pattern for both memory and logic. By using a common grating pattern for both memory and logic, a corresponding layer of the integrated circuit can be reliably and affordably manufactured using sub-wavelength lithography.
    Type: Grant
    Filed: April 27, 2009
    Date of Patent: June 12, 2012
    Assignee: Carnegie Mellon University
    Inventors: Lawrence T. Pileggi, Daniel Morris
  • Patent number: 8200147
    Abstract: A wireless communication system for geographically controlling a communication area includes an access point for communicating with a terminal in a first area, and a jammer for generating noise for intercepting communication between the access point and a terminal in a second area. A jamming boundary for dividing an area in which the terminal can communicate with the access point and an area in which the terminal cannot communicate with the access point in an area in which the first area and the second area are overlapped is formed, and the jamming boundary is formed by a ratio between power of a signal transmitted to the terminal by the access point and power of a signal of the noise.
    Type: Grant
    Filed: November 25, 2009
    Date of Patent: June 12, 2012
    Assignee: Korea University Industry and Academy Collaboration Foundation
    Inventors: Hee-Jo Lee, Yu-Seung Kim, Hyogon Kim
  • Patent number: 8197499
    Abstract: Disclosed are compositions, methods, and kits for joining together non-conjoined lumens in a patient's body including vascular lumens. More particularly, in various aspects, this invention provides compositions, methods, and kits for joining such non-conjoined lumens, including small lumens typically requiring microsurgical technique.
    Type: Grant
    Filed: December 19, 2008
    Date of Patent: June 12, 2012
    Assignee: The Board of Trustees of the Leland Stanford Junior University
    Inventors: Geoffrey C. Gurtner, Gerald G. Fuller, Michael T. Longaker, Jayakumar Rajadas, Gordon Saul, C. Travis Rappleye, Evgenia Mandrusov
  • Patent number: 8197763
    Abstract: The desulfurization of fossil fuels is effected by the combination of fossil fuels with an aqueous mixture of hydroperoxide and quaternary ammonium fluoride phase transfer catalyst, the mixture then subjected to ultrasound to oxidize sulfur compounds present in the fuels. The polar oxidized species are removed via extraction. Another aspect is a portable, continuous ultrasound assisted desulfurization device having a sonoreactor for subjecting mixtures of fossil fuels to sonication to effect removal of sulfur containing compounds.
    Type: Grant
    Filed: September 13, 2007
    Date of Patent: June 12, 2012
    Assignee: University of Southern California
    Inventors: Teh-Fu Yen, Meng-Wei Wan