Abstract: A system that incorporates teachings of the present disclosure may include, for example, a memory device having a memory cell to selectively store holes by photon and bias voltage induction as a representation of binary values.

Abstract: A pixel circuit includes an LED having an anode that receives a driving current and a cathode that receives a scan signal, and a driving circuit including: a switch unit operable according to a voltage signal, and adapted for permitting transfer of a data signal when operating in an on state; a capacitor having a first end coupled to the switch unit, and a second end; a first transistor having a first terminal that is coupled to the second end of the capacitor, a second terminal that is coupled to the anode of the LED, and a control terminal that is coupled to the first end of the capacitor; and a second transistor having a first terminal that is adapted for coupling to the voltage source, a second terminal that is coupled to the first terminal of the first transistor, and a control terminal that is adapted for receiving a reference voltage.

Abstract: The present invention relates to stable concentrated enzymatic compositions suitable for storage under ambient conditions, while maintaining their intended enzymatic activity. The invention further relate to kits comprising concentrated enzymatic compositions, methods for preparing debriding solutions from said concentrated enzymatic compositions and methods of using the diluted debriding solutions.

Abstract: The presently disclosed subject matter provides methods for increasing perfusion in hypoxic regions of tissues in subjects. Also provided are methods for treating diseases and/or disorders associated with hypoxia in subjects, methods for increasing sensitivity of tumors to radiation and/or chemotherapy treatments, methods for delaying tumor growth in subjects, and methods for inhibiting tumor blood vessel growth in subjects. In some embodiments, the presently disclosed methods involve administering to subjects in need thereof a first composition selected from the group consisting of a nitrosylated hemoglobin and an agent that induces nitrosylation of endogenous hemoglobin in the subject and a second composition comprising a hyperoxic gas. In some embodiments, the presently disclosed methods also include treating a tumor with radiation therapy, chemotherapy, photodynamic therapy, immunotherapy, or combinations thereof. Also provided are inhalable gases that can be employed in the presently disclosed methods.

Abstract: A two-dimensional left-handed metamaterial that functions as a two-dimensional electromagnetic wave propagation medium in which the equivalent permittivity and permeability of the medium are both negative, exhibits superior low-loss, broadband characteristics as a left-handed material, and has a simple constitution, enabling low-cost manufacture.

Abstract: Oligopeptides which can be used to treat cancer are disclosed. Further disclosed are methods of treating cancer, including breast cancer, skin cancer, prostate cancer and multiple myeloma (MM). These methods include administration of a polypeptide encoded by the Mesd gene, or an oligopeptide comprising a contiguous subsequence of a Mesd polypeptide.

Abstract: A method for calibrating a phased-array antenna that involves transmitting a signal from a transmitting element, and sequentially receiving the transmitted signal at two receiving elements each spaced a first distance from the transmitting element. This step is then repeated one or more times, but transmitting from a different transmitting element in each repetition of the step, until each element being calibrated has received at least one transmission. Then, the first distance is changed to a second distance, and the steps are repeated one or more times to gather additional measurements. These measurements allow the determination from the received signals of two separate element mutual coupling ratios, one ratio for one subset of the elements being calibrated and the other for a second subset comprising the remaining elements being calibrated.

Abstract: An Ni3Al-based intermetallic compound of the present invention comprises greater than 5 at % and not greater than 13 at % of Al, not less than 9.5 at % and less than 17.5 at % of V, not less than 0 at % and not greater than 5 at % of Nb, not less than 50 weight ppm and not greater than 1000 weight ppm of B, and the remaining portion consisting of Ni and inevitable impurities, and has a dual multi-phase microstructure comprising a primary L12 phase and an (L12+D022) eutectoid microstructure.

Abstract: The present invention provides prebiotic and probiotic compositions containing human milk oligosaccharides and methods of use that selectively promote the growth of beneficial gut bacteria.

Abstract: Heterocyclic compounds having a relatively flexible backbone are used to create combinatorial libraries that permit screening for lead compounds and selection of drug candidates for a variety of uses in human and veterinary medicine as well as in agriculture. The compounds of the library generally differ in ring size and chirality of substituents on the ring. Also disclosed are methods for providing and screening these libraries, preferably in an automated or computerizable manner, such as by using a computer program to virtually screen the compounds in order to identify those that are predicted to have bioactive conformations that should give rise to desirable biological effects.

Abstract: The present invention discloses a solar cell having a multi-layered structure that is used to generate, transport, and collect electric charges. The multi-layered nanostructure comprises a cathode, a conducting metal layer, a photo-active layer, a hole-transport layer, and an anode. The photo-active layer comprises a tree-like nanostructure array and a conjugate polymer filler. The tree-like nanostructure array is used as an electron acceptor while the conjugate polymer filler is as an electron donor. The tree-like nanostructure array comprises a trunk part and a branch part. The trunk part is formed in-situ on the surface of the conducting metal layer and is used to provide a long straight transport pathway to transport electrons. The large contact area between the branch part and the conjugate polymer filler provides electron-hole separation.

Abstract: A system for providing enhanced background rejection in thick tissue contains an aberrating element for introducing controllable extraneous spatial aberrations in an excitation beam path; at least one mirror capable of directing received laser pulses to the aberrating element; an objective; a beam scanner imaged onto a back aperture of the objective so that the beam scanner steers beam focus within the thick tissue; and a detector for recording signals produced by the tissue. An associated method comprises the steps of acquiring two-photon excited fluorescence of thick tissue without extraneous aberrations; introducing an extraneous aberration pattern in an excitation beam path; acquiring two-photon excited fluorescence of the thick tissue having the introduced extraneous aberration pattern; and subtracting the two-photon excited fluorescence with extraneous aberrations from the acquired standard two-photon excited fluorescence of the thick tissue without extraneous aberrations.

Abstract: Optical proximity correction (OPC) is a technique used to compensate for optical distortions, process effects, or both, by modifying a pattern that is used during lithography. A reference OPC model is used to create an OPC design layout pattern based on pre-distorting a desired design layout pattern associated with an integrated circuit (IC). The OPC design layout pattern is used when the IC is produced, such that the fabricated IC ideally matches the desired design layout pattern. The present invention relates to using a regression OPC model to create estimated fragment movements of the desired design layout pattern. The estimated fragment movements are then provided as initial fragment movements to the reference OPC model, which then creates the OPC design layout pattern. The initial fragment movements provided by the regression OPC model may reduce the number of iterations needed by the reference OPC model, thereby reducing computation time.

Abstract: Provided are fatty acid amides of amino acids, uses thereof and pharmaceutical compositions including them.

Abstract: Various implementations of an interface device, along with associated methods and systems, are described in which the interface device has a housing with a transformable form factor, and a transformation assembly that can change the form factor of the housing. At least one of the form factors of the housing has a shape that corresponds to data associated with the interface device.

Abstract: A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures.

Abstract: Acoustical-based methods that increase tissue oxygenation, and equipment for carrying out the methods, are provided. The methods involve exposing tissue to low frequency sound in order to increase blood flow in the tissue, and hence oxygenation of the tissue. The methods may be used to treat or prevent disorders related to ischemia and low blood flow, such as shock, stroke and congestive heart failure.

Abstract: A method of manufacturing a liquid crystal display includes; disposing a thin film transistor having an output terminal on a first substrate, disposing a pixel electrode in connection with the output terminal, disposing an inorganic layer on the pixel electrode, and converting the inorganic layer to a first alignment layer by disposing a mask on the inorganic layer and radiating an ion beam in a plurality of directions.

Abstract: The present invention relates to methods and compositions for modulating angiogenesis. In particular, the present invention relates to Pigment Epithelial-derived Factor (PEDF) fragments for use in modulating angiogenesis and treating angiogenesis mediated disease.

Abstract: A novel isoform of tropomyosin is disclosed. The isoform is closely related to epithelial human tropomyosin (hTM) and more particularly to hTM5 except the last coding exon. The novel isoform, is called TC22. Northern blot analysis with TC22-specific probe revealed that normal culture cell lines and normal epithelial tissues expressed very little, if at all, TC22 message, whereas their transformed counterparts and tumor tissues including dysfunction of the alimentary canal, significantly increased the expression of TC22. Assays directed at determining the level of TC22 are useful in diagnostics and therapeutics of dysfunction of the alimentary canal. Specific antibodies and mimics for TC22 are also disclosed for use in diagnostics and therapeutics of dysfunction of the alimentary canal.