Abstract: The present invention describes a method for synthesis of relatively low molecular weight imprinted polymers using living polymerization, and their application in analytical chemistry, pharmacology, medicine and the food industry. Specifically the low-molecular weight polymers are synthesized by the polymerization of functional monomers in the presence of a template, such as a biological receptor, enzyme, nucleic acid, cell, virus, microorganism, tissue sample or drug using living initiator. The conditions of living polymerization ensure a relatively small size of synthesized molecules. Synthesized in this way molecules (dimers, oligomers, polymers, or their mixture) have a higher affinity to the template than the original monomers and can rebind it in vitro and/or in vivo.

Abstract: The present invention is a novel biosensor composed of mOrange2 and mCherry fluorescent proteins operably linked via a linker, which provides a distinct color change upon separation of the fluorescent proteins.

Abstract: 6- and 7-substituted coumarin and related 6- and 7-substituted 1H-quinolin-2-one compounds, pharmaceutical compositions containing these compounds, and methods for their pharmaceutical use are disclosed. In certain embodiments, the 7-substituted coumarin and related 7-substituted 1H-quinolin-2-one compounds mimic or exceed the high level of pharmacological activity of discodermolide. In other embodiments, their preparation involves more readily available materials, higher yield processes and/or simpler synthetic sequences. In yet other embodiments, the compounds of the invention represent structurally simpler, therapeutically active analogues of discodermolide than heretofore known and may be useful as microtubule stabilizers and, inter alia, for treating and/or preventing cancer and other diseases, disorders, and/or conditions mediated by the stabilization of microtubules.

Abstract: An electricity charging module using a hysteresis switch includes a storage capacitor that preliminarily stores electrical energy supplied from an external power source, a charging unit for preventing over-charging or over-discharging through monitoring of the charging state of the rechargeable battery, and a hysteresis switch that has a larger turn-on voltage level than the turn-off voltage level, and located between the storage capacitor and the charging unit, thereby electrically connecting or disconnecting the storage capacitor with the charging unit.

Abstract: The present invention relates to a robot motion data generation method and a generation apparatus using image data, and more specifically to a robot action data generation method for perceiving motion of an object from a consecutive first image frame and a second image frame including image information on the moving object, and for generating robot action data from the perceived motion, comprising the steps of: a first step of performing digital markings at plural spots on top of the object of the first image frame, and storing first location coordinates values of the digital markings in tree type; a second step of storing peripheral image patterns of each digital marking in association with the first location coordinates values; a third step of recognizing image data identical with peripheral image patterns of each of the first location coordinates values from the second image frame, and finding out changed second location coordinates values from the first location coordinates values; a fourth step of extrac

Abstract: A movable-body navigation information display unit is provided. In the movable-body navigation information display unit, a driver can intuitively and accurately recognize a relation between navigation information and a real picture or a real landscape. In addition, it is possible to avoid a state that visibility of a caution-needed picture such as a pedestrian in the real picture and a real picture of a road construction site is inhibited by an image of the navigation information. An image data creating section (405) matches road shape data with a road shape model to estimate posture data. In addition, the image data creating section creates picture (image) data for accurately compositing and displaying the image of the navigation information in an appropriate position in a real picture (or in a real landscape) of a road ahead of a movable body, and displays the navigation information as a three-dimensional icon or the like. A picture display section (5) performs display based on the picture data.

Abstract: An apparatus and computer program are disclosed for processing at least one workpiece using a rotary tool with rotating member for contacting and processing the workpiece. The methods include oscillating the rotary tool laterally with respect to a selected propagation path for the rotating member with respect to the workpiece to define an oscillation path for the rotating member. The methods further include obtaining force signals or parameters related to the force experienced by the rotary tool at least while the rotating member is disposed at the extremes of the oscillation. The force signals or parameters associated with the extremes can then be analyzed to determine a lateral position of the selected path with respect to a target path and a lateral offset value can be determined based on the lateral position. The lateral distance between the selected path and the target path can be decreased based on the lateral offset value.

Abstract: The present invention relates to engineered blood vessels and methods of making such vessels using matrices comprising endothelial and smooth muscle cells, or cells capable of differentiating into endothelial and smooth muscle cell lineages (e.g., stem cells, or the progenitors thereof).

Abstract: An antenna radome is provided. The antenna radome comprises an antenna radome substrate and a unit cell. The unit cell is formed on a surface of the antenna radome substrate, and the unit cell is perpendicular to a magnetic field direction of an antenna. The unit cell comprises a plurality of conductors.

Abstract: A density-based data clustering method, comprising a parameter-setting step, a first retrieving step, a first determination step, a second determination step, a second retrieving step, a third determination step and first and second termination determination steps. The parameter-setting step sets parameters. The first retrieving step retrieves one data point and defines neighboring points. The first determination step determines whether the number of the data points exceeds the minimum threshold value. The second determination step arranges a plurality of first border symbols. The second retrieving step retrieves one seed data point from the seed list, arranges a plurality of second border symbols and defines seed neighboring points. The third determination step determines whether a data point density of searching ranges of the seed neighboring points is the same. The first termination determination step determines whether the clustering is finished.

Abstract: A composite biocompatible hydrogel material includes a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa. A calcium comprising salt is disposed in at least some of the pores. The porous polymer matrix can comprise cellulose, including bacterial cellulose. The composite can be used as a bone graft material. A method of tissue repair within the body of animals includes the steps of providing a composite biocompatible hydrogel material including a porous polymer matrix, the polymer matrix including a plurality of pores and providing a Young's modulus of at least 10 GPa, and inserting the hydrogel material into cartilage or bone tissue of an animal, wherein the hydrogel material supports cell colonization in vitro for autologous cell seeding.

Abstract: A fiber wadding for filling bone defects having a flocculent three-dimensional structure is disclosed. The fiber wadding includes a plurality of fibers that contain a biodegradable resin as a principal component and a siloxane. Outside diameter of the plurality of fibers of the wadding is from about 0.05 ?m to about 30 ?m. Bulk density of the fiber wadding is about 0.005-0.3 g/cm3.

Abstract: An audio processing apparatus generates a suppression coefficient sequence that is composed of coefficient values corresponding to frequency components of an audio signal, the frequency components being multiplied by the corresponding coefficient values to suppress noise components of the audio signal. In the audio processing apparatus, a characteristic value calculation unit calculates a noise characteristic value depending on a shape of a magnitude distribution of the audio signal. An intensity setting unit variably sets a suppression intensity of the noise components based on the noise characteristic value. A coefficient sequence generation unit generates the suppression coefficient sequence based on the audio signal and the suppression intensity.

Abstract: The invention provides a cancer therapeutic and imaging agent comprising a solution containing Gum Arabic coated 198Au nanoparticles. The Gum Arabic coated 198Au nanoparticles have been demonstrated experimentally shown to have a surprising efficacy for a single dose direct injection, reducing tumors in analog mice by 82% over a short period of time. The particles of the invention have a believed optimal size for therapy and imaging applications, and can be used as a theranostic agent in the treatment of needle accessible cancers. The invention also provides a method for forming Gum Arabic coated 198Au nanoparticles. A gold foil is irradiated to produce 198Au foil. The foil is dissolved to form radioactive gold salt. The salt is dried, and then reconstituted to form a 198Au nanoparticle precursor. The precursor is reduced with a reducing agent in an aqueous solution including Gum Arabic to form Gum Arabic coated 198Au nanoparticles.

Abstract: Provided is an automatic detection kit for automatically detecting HLA alleles using a real-time polymerase chain reaction (PCR). The real-time PCR is performed on DNA isolated from a sample using a primer which is able to specifically bind to HLA alleles and a fluorescent probe which is able to detect amplification of the HLA alleles in real time, and the HLA allele typing is performed by analyzing a fluorescence value obtained from the real-time PCR using an HLA automatic typing program.

Abstract: A system is provided for migrating a VM over a WAN. A first server has a VM. The first and second servers are operatively connected over the WAN by a virtual private local area network service. The first server migrates the VM to the second server by coping files and state of the VM to the second server without interrupting the interactive software on the VM. During a last round of migrating the VM, for packets intended for the VM on the first server, the first server buffers the packets in a buffer as buffered packets. Instead of delivering the buffered packets to the VM, the first server transmits the buffered packets to the second server. The second server plays the buffered packets to the VM migrated to and operating on the second server, such that buffered packets are played before current packets currently received from the clients are played.

Abstract: A gas sensor is described which incorporates a sensor stack comprising a first film layer of a ferromagnetic material, a spacer layer, and a second film layer of the ferromagnetic material. The first film layer is fabricated so that it exhibits a dependence of its magnetic anisotropy direction on the presence of a gas, That is, the orientation of the easy axis of magnetization will flip from out-of-plane to in-plane when the gas to be detected is present in sufficient concentration. By monitoring the change in resistance of the sensor stack when the orientation of the first layer's magnetization changes, and correlating that change with temperature one can determine both the identity and relative concentration of the detected gas.

Abstract: The present invention relates to triazine compounds having sodium channel blocking properties, and to use of the compounds for preparation of medicaments for treatment of associated disorders. The triazine compounds are of formula (I) wherein: R1 is hydrogen or a substituent group; R2 is amino or a substituent group; N* is amino when R1 is hydrogen or ?NH when R1 is a substituent group; R3 and R4 are both carbocyclic, heterocyclic or alkyl groups and may be same or different; and R5 is hydrogen, alkyl or a cyclic aryl group, with the proviso that: when R3 and R4 are both alkyl they are linked to form a cycloalkyl group, and R5 is a cyclic aromatic group; and when R3 and R4 are both carbocyclic or heterocyclic groups, R5 is hydrogen or an alkyl group; or a salt thereof.

Abstract: Compounds of formula I and their metabolites are potent mediators of an inflammatory response: (I) where a, b, c, d, e, f, V, W, X, Y, Ra, Ra?, Rb, Rb?, Rc, and Rc? are defined herein. In particular, the compounds of the invention are candidate therapeutics for treating inflammatory conditions.

Abstract: A technique is described herein for monitoring the operational state of a fuel cell stack by the detection of nonlinearity in such a manner that an external test signal for frequency response is generated and applied to the fuel cell stack during operation, the resulting signal output from the fuel cell stack is measured, and the harmonic content of the measured signal is analyzed, the method including: applying a multiple frequency test signal comprising at least two sinusoidal waves as the test signal for frequency response to the fuel cell stack; and analyzing the resulting current or voltage signal output from the fuel cell stack.