Patents Assigned to University
  • METHOD FOR GREEN SAND MOLDING
    Publication number: 20120132391
    Abstract: The object of the present invention is to provide a method for green sand molding that prevents a bad casting by producing a mold that does not have a brittle surface. The method comprises the steps of filling the green sand into a flask while fluidizing the green sand by aeration at a pressure between 0.05 and 0.18 MPa, and squeezing the green sand that has been filled in the flask, wherein a mold is produced so that the friability of the mold is 10 or less. The friability is a value that is calculated by the following steps: putting the mold in a rotating cylindrical sieve that has a diameter of 177.8 mm and USA sieve size No. 8, rotating the cylindrical sieve at 57 rpm for 60 seconds, dividing the weight of the sand that has passed through the sieve by the weight of the sand that has been put into the sieve, and multiplying the quotient by 100.
    Type: Application
    Filed: July 25, 2011
    Publication date: May 31, 2012
    Applicants: Western Michigan University, SINTOKOGIO, LTD.
    Inventors: Hiroyasu MAKINO, Sam Ramrattan
  • LIQUID ANODE RADIATION SOURCE
    Publication number: 20120133265
    Abstract: The present disclosure relates to a liquid anode radiation source (10) having the ability of turning upside down. The liquid anode radiation source (10) comprises a body (12) equipped with inlet and outlet having a wall (15) limiting the anode space (17), where the outlet connected to the inlet outside the body (12) will define a continuous flow path closing through the body, the inlet has a wall limiting an internal cross-section changing towards the anode space (17), wherein the cross-section of the inlet a deflector (11) is arranged in a position free of contacting the wall, filling out the cross-section partially and movable to the direction perpendicular to the cross-section; the liquid anode material (14) arranged in the flow path; the circulation unit inserted in the flow path in such a way that it can ensure the unidirectional movement of the anode material in the flow path.
    Type: Application
    Filed: November 25, 2011
    Publication date: May 31, 2012
    Applicants: University of Szeged-South-Lowland Cooperative Research Center of Life Sciences and Material Scie, GE HUNGARY KFT.
    Inventor: Róbert Kákonyi
  • Cross-Linking of Superoxide Dismutase Monomers
    Publication number: 20120134978
    Abstract: A stabilized superoxide dismutase (SOD1) analogue, wherein the side chains of two amino acids on two different SOD1 monomers are connected is provided. A method of producing a stabilized superoxide disumutase (SOD1) analogue comprises reacting a first SOD1 monomer, a second SOD1 monomer, and a cross-linker.
    Type: Application
    Filed: June 2, 2010
    Publication date: May 31, 2012
    Applicant: Brandeis University
    Inventor: Jeffrey N. Agar
  • Multi-Shell Microspheres With Integrated Chromatographic And Detection Layers For Use In Array Sensors
    Publication number: 20120135396
    Abstract: The development of miniaturized chromatographic systems localized within individual polymer microspheres and their incorporation into a bead-based cross-reactive sensor array platform is described herein. The integrated chromatographic and detection concept is based on the creation of distinct functional layers within the microspheres. In this first example of the new methodology, complexing ligands have been selectively immobilized to create “separation” layers harboring an affinity for various analytes. Information concerning the identities and concentrations of analytes may be drawn from the temporal properties of the beads' optical responses, Varying the nature of the ligand in the separation shell yields a collection of cross-reactive sensing elements well suited for use in array-based micro-total-analysis systems.
    Type: Application
    Filed: November 23, 2011
    Publication date: May 31, 2012
    Applicant: Board of Regents, The University of Texas System
    Inventors: John T. McDevitt, Adrian Goodey, Jason Shear, Eric Anslyn, Dean P. Neikirk
  • HEMICELLULOSE-DEGRADING ENZYMES
    Publication number: 20120135474
    Abstract: The present disclosure provides methods for the conversion of hemicellulose into fermentable sugars using enzymes isolated from Prevotella bryantii. Hemicellulose-degrading enzymes include an endoxylanase, a ?-xylosidase, a bifunctional ?-xylosidase and ?-glucosidase, a bifunctional arabinofuranosidase and ?-xylosidase, a glucuronidase, and an acetyl xylan esterase. The enzymes can be used to release sugars present in hemicellulose for subsequent fermentation to produce value-added products such as ethanol.
    Type: Application
    Filed: April 27, 2010
    Publication date: May 31, 2012
    Applicant: The Board of Trustees of the University of Illinois
    Inventors: Isaac K. O. Cann, Shinichi Kiyonari, Dylan Dodd, Yejun Han, Roderick I. Mackie
  • METHODS OF FORMING HYDROPHOBIC SILICON DIOXIDE LAYER AND FORMING ORGANIC THIN FILM TRANSISTOR
    Publication number: 20120135562
    Abstract: A method of forming a hydrophobic silicon dioxide layer is provided. A substrate is provided. Thereafter, a hydrophobic silicon dioxide layer is formed on the substrate by using a plasma chemical vapour deposition (CVD) system, in which tetraethyl orthosilicate (TEOS) and an oxygen-containing gas are introduced at a reactive temperature between 25° C. and 150° C. A method of forming an organic thin film transistor (OTFT) including the hydrophobic silicon dioxide layer as a gate insulating layer is also provided. In the present invention, the hydrophobic silicon dioxide layer can be directly formed at low temperature without using the conventional surface modification treatment. Accordingly, the process is simplified and the cost is reduced.
    Type: Application
    Filed: January 14, 2011
    Publication date: May 31, 2012
    Applicant: National Taiwan University of Science and Technology
    Inventors: Ching-Lin Fan, Ping-Cheng Chiu, Chang-Chih Lin
  • HEMOGLOBIN CONTRAST IN MAGNETO-MOTIVE OPTICAL DOPPLER TOMOGRAPHY, OPTICAL COHERENCE TOMOGRAPHY, AND ULTRASOUND IMAGING METHODS AND APPARATUS
    Publication number: 20120136238
    Abstract: A novel contrast mechanism for imaging blood flow using magneto-motive optical Doppler tomography (MM-ODT), Optical Coherence Tomography, and Ultrasound. MM-ODT, OCT, and ultrasound combined with an externally applied temporally oscillating high-strength magnetic field detects erythrocytes moving according to the field gradient.
    Type: Application
    Filed: September 9, 2011
    Publication date: May 31, 2012
    Applicant: Board of Regents, The University of Texas System
    Inventor: Thomas E. Milner
  • PIEZOELECTRIC POLYMER MATERIAL AND METHOD FOR PRODUCING SAME
    Publication number: 20120132846
    Abstract: The invention provides a piezoelectric polymer material comprising a helical chiral polymer having a weight average molecular weight of from 50,000 to 1,000,000 and optical activity, the piezoelectric polymer material having: crystallinity as obtained by a DSC method of from 20% to 80%; a transmission haze with respect to visible light of 50% or less; and a product of the crystallinity and a standardized molecular orientation MORc, which is measured with a microwave transmission-type molecular orientation meter at a reference thickness of 50 ?m, of from 40 to 700.
    Type: Application
    Filed: February 9, 2012
    Publication date: May 31, 2012
    Applicants: A school Corporation Kansai University, Mitsui Chemicals, Inc.
    Inventors: Mitsunobu YOSHIDA, Shunsuke Fujii, Hitoshi Onishi, Yoshiro Tajitsu, Taizo Nishimoto, Kazuhiro Tanimoto, Kenichi Goto
  • MONITORING THE OPERATIONAL STATE OF A FUEL CELL STACK
    Publication number: 20120135327
    Abstract: A technique is described herein for monitoring the operational state of a fuel cell stack by the detection of nonlinearity in such a manner that an external test signal for frequency response is generated and applied to the fuel cell stack during operation, the resulting signal output from the fuel cell stack is measured, and the harmonic content of the measured signal is analyzed, the method including: applying a multiple frequency test signal comprising at least two sinusoidal waves as the test signal for frequency response to the fuel cell stack; and analyzing the resulting current or voltage signal output from the fuel cell stack.
    Type: Application
    Filed: May 17, 2011
    Publication date: May 31, 2012
    Applicants: Kangnam University Industry-Academia Cooperation Foundation, HYUNDAI MOTOR COMPANY
    Inventors: Kwi Seong Jeong, Seung Chan Oh, Young Bum Kum, Sae Hoon Kim, Jung Do Suh, Duck Whan Kim, Young Hyun Lee, Seung Ryeol Yoo, Myung Ju Jung, Jong Guen Yoon
  • SINGLE MOLECULE SPECTROSCOPY FOR ANALYSIS OF CELL-FREE NUCLEIC ACID BIOMARKERS
    Publication number: 20120135874
    Abstract: The present invention relates, e.g., to a method for detecting a nucleic acid molecule of interest in a sample comprising cell-free nucleic acids, comprising fluorescently labeling the nucleic acid molecule of interest, by specifically binding a fluorescently labeled nanosensor or probe to the nucleic acid of interest, or by enzymatically incorporating a fluorescent probe or dye into the nucleic acid of interest, illuminating the fluorescently labeled nucleic acid molecule, causing it to emit fluorescent light, and measuring the level of fluorescence by single molecule spectroscopy, wherein the detection of a fluorescent signal is indicative of the presence of the nucleic acid of interest in the sample.
    Type: Application
    Filed: May 6, 2010
    Publication date: May 31, 2012
    Applicant: The Johns Hopkins University
    Inventors: Jeff Tza-Huei Wang, Kelvin J. Liu, Christopher M. Puleo
  • Small Molecule Antagonists of Phosphatidylinositol-3,4,5-Triphosphate (PIP3) and Uses Thereof
    Publication number: 20120136033
    Abstract: Disclosed are a new class of non-lipid small molecule inhibitors which interfere with the interaction between PIP3 and pleckstrin homology domains. These molecules target a broad range of PIP3-dependent signaling events in vitro and exert significant anti-tumor activity in vivo. The small molecule inhibitors of the invention can be used alone or together with tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) or other cancer medicament to treat cancer. Small molecule inhibitors of the invention act synergistically in combination with TRAIL in treating cancer. Pharmaceutical compositions and methods for treating cancer are provided.
    Type: Application
    Filed: May 17, 2010
    Publication date: May 31, 2012
    Applicants: President and Fellows of Harvard College, Tufts University
    Inventors: Alexei Degterev, Mikhail Reibarkh, Gerhard Wagner, Junying Yuan
  • SINGLE NUCLEOTIDE POLYMORPHISMS (SNP) AND ASSOCIATION WITH RESISTANCE TO IMMUNE TOLERANCE INDUCTION
    Publication number: 20120135014
    Abstract: This application discloses methods, systems and kits for correlating the presence or absence of certain nucleic acid sequences within a population with the ability to create immune tolerance in that same population. Tolerance can be induced by solo or repeated administration of antigen, including soluble antigens administered either intravenously or sublingually. This application also discloses methods for detecting variants. In addition the application addresses the use or avoidance of non steroidal anti inflammatory drugs in therapy.
    Type: Application
    Filed: April 20, 2009
    Publication date: May 31, 2012
    Applicant: The University of Tennessee Research Foundation
    Inventors: Arnold E. Postlethwaite, Weikuan Gu
  • HEARING AID FITTING PROCEDURE AND PROCESSING BASED ON SUBJECTIVE SPACE REPRESENTATION
    Publication number: 20120134521
    Abstract: A system for hearing assistance devices to assist hearing aid fitting applied to individual differences in hearing impairment. The system is also usable for assisting fitting and use of hearing assistance devices for listeners of music. The method uses a subjective space approach to reduce the dimensionality of the fitting problem and a non-linear regression technology to interpolate among hearing aid parameter settings. This listener-driven method provides not only a technique for preferred aid fitting, but also information on individual differences and the effects of gain compensation on different musical styles.
    Type: Application
    Filed: February 8, 2012
    Publication date: May 31, 2012
    Applicant: University of California
    Inventors: David Wessel, Eric Battenberg, Andrew Schmeder, Kelly Fitz, Brent Edwards
  • External Preparation Containing NSAIDs And Method For Producing The External Preparation
    Publication number: 20120135955
    Abstract: Disclosed is an external preparation containing nonsteroidal anti-inflammatory drugs (NSAIDs), which is suppressed in cytotoxicity induced by the NSAIDs. Also disclosed is a method for producing the external preparation. The present invention is based on the finding that skin disorders induced by nonsteroidal anti-inflammatory drugs (NSAIDs) can be suppressed when the NSAIDs form intermolecular compounds together with trehalose, which is an example of disaccharides. A disaccharide other than trehalose may be used therefor.
    Type: Application
    Filed: July 21, 2010
    Publication date: May 31, 2012
    Applicants: The University of Tokyo, Next21 K.K.
    Inventors: Yuichi Tei, Nobuo Sasaki, Shigeki Suzuki
  • HYDROXYETHYL STARCH-CONTAINING POLYPEPTIDE COMPOSITIONS
    Publication number: 20120134958
    Abstract: The invention provides compositions containing hydroxyethyl starch and polypeptides, including therapeutic polypeptides such as interleukin-11, that provide for enhanced stability of the polypeptide following storage at room temperature or elevated temperatures.
    Type: Application
    Filed: February 2, 2012
    Publication date: May 31, 2012
    Applicants: The Regent of the University of Colorado, Wyeth
    Inventors: Nicholas W. WARNE, Rebecca L. Koval, John Carpenter, Theodore W. Randolph, Suchart Chongpraset
  • METHOD FOR FABRICATION OF SILICONE COMPOSITE WITH ANTIMICROBIAL COATING
    Publication number: 20120135250
    Abstract: An antimicrobial article prepared by a method includes forming an antimicrobial mixture by adding a calculated amount of antimicrobial agent to a solution of water and alcohol, depositing the antimicrobial mixture in a container, the antimicrobial mixture having a thickness of 0.1 ?m to 10 ?m, evaporating the water and alcohol of the antimicrobial mixture to form the layer of antimicrobial coating, adding silicone resin on top of the layer of antimicrobial coating and allow the silicone resin to permeate and crosslink with the layer of antimicrobial coating, and removing the silicone composite with the layer of antimicrobial coating from the container.
    Type: Application
    Filed: February 2, 2012
    Publication date: May 31, 2012
    Applicant: The Hong Kong Polytechnic University
    Inventors: Chak Yin TANG, Da-zhu CHEN, Tai Man YUE, Yuen Yee CHAN
  • NUCLEIC ACIDS ENCODING T2R, A NOVEL FAMILY OF TASTE RECEPTORS
    Publication number: 20120135447
    Abstract: The invention provides isolated nucleic acid and amino acid sequences of taste cell specific G-protein coupled receptors, antibodies to such receptors, methods of detecting such nucleic acids and receptors, and methods of screening for modulators of taste cell specific G-protein coupled receptors.
    Type: Application
    Filed: October 11, 2011
    Publication date: May 31, 2012
    Applicants: The Govt. of the U.S.A. as represented by the Secretary of the Dept. of Health & Human Services, The Regents of the University of California
    Inventors: Charles S. Zuker, Jon Elliot Adler, Mark Hoon, Nick Ryba, Ken Mueller
  • Imprinted Biomimetic Catalysts for Cellulose Hydrolysis
    Publication number: 20120136180
    Abstract: The present disclosure describes methods and biomimetic catalysts useful for hydrolyzing glucose polymers, such as cellulose, and oligomers, such as cellobiose, to glucose for the subsequent production of ethanol.
    Type: Application
    Filed: March 2, 2010
    Publication date: May 31, 2012
    Applicant: The Trustees of the University of Pennsylvania
    Inventors: Stephen Roth, Daeyeon Lee
  • PEPTIDES WHOSE UPTAKE IN CELLS IS CONTROLLABLE
    Publication number: 20120134922
    Abstract: Disclosed herein, in certain embodiments, is a selective transport molecule with increased in vivo circulation. In some embodiments, a selective transport molecule disclosed herein has the formula (A—X—B—C)n—M, wherein C is a cargo moiety; A is a peptide with a sequence comprising 5 to 9 consecutive acidic amino acids, wherein the amino acids are selected from: aspartates and glutamates; B is a peptide with a sequence comprising 5 to 20 consecutive basic amino acids; X is a linker; and M is a macromolecular carrier.
    Type: Application
    Filed: July 15, 2010
    Publication date: May 31, 2012
    Applicant: The Regents of the University of California
    Inventors: Roger Tsien, Emilia Olson, Tao Jiang, Quyen Nguyen, Mike Whitney
  • SYSTEMS AND METHODS FOR GLOBAL VOLTAGE SECURITY ASSESSMENT IN POWER SYSTEMS
    Publication number: 20120136643
    Abstract: Systems and methods for global voltage security assessment in power systems are disclosed herein. In one embodiment, a method for assessing voltage security in a power system having a number (i) of buses includes capturing a change in bus voltage and a change in line reactive power for at least some of the buses in the power system, for each of the i number of buses, calculating a voltage assessment index) (?i) for as follows: ? i = ? j ? ? ? ? Q ij ? ? ? V i where ?Vi is the change in bus voltage and ?Qij is the change in line reactive power from a connection j over a predetermined period of time. The method further includes assessing a current voltage security status of the power system based on the calculated voltage assessment index (?i).
    Type: Application
    Filed: May 23, 2011
    Publication date: May 31, 2012
    Applicant: Washington State University
    Inventors: Vaithianathan Venkatasubramanian, Xing Liu