Patents Assigned to University
  • Patent number: 8195580
    Abstract: Methods, computer-readable media, and systems are provided for the detection of propagating phase gradients using model field theory of non-Gaussian mixtures. One embodiment of the invention is directed to a method for identifying phase cones in a data set. The method includes generating an initial set of values of parameters (?A,?A,tA) for a preset number of cones, initializing a covariance matrix with high values, evaluating the ratio of volume of a phase cone over total observed space-time volume, comparing the data set with a model, estimating a class probability density function, and generating a revised set of values of parameters (?A,?A,tA).
    Type: Grant
    Filed: May 30, 2008
    Date of Patent: June 5, 2012
    Assignees: The University of Memphis Research Foundation, The United States of America, as Represented by the Secretary of the Air Force
    Inventors: Robert Kozma, Leonid Perlovsky
  • Patent number: 8193313
    Abstract: The present invention relates to peptide vaccines, pharmaceutical compositions thereof, and associated methodologies that promote the immune-mediated regression of tumors expressing an onconeural antigen, e.g. a cdr-2 antigen, HuD antigen. The cancer peptide vaccines of the present invention are antigenic peptides capable of being faithfully presented on the MHC I complex of a target cell or antigen presenting cell. This external cellular presentation of these peptides promotes a specific cytotoxic T lymphocyte (CTL)-mediated immune response against tumor cells expressing these proteins, thereby, inducing immunological reactivity.
    Type: Grant
    Filed: March 14, 2011
    Date of Patent: June 5, 2012
    Assignee: The Rockefeller University
    Inventor: Robert B. Darnell
  • Patent number: 8193500
    Abstract: A discrimination filtering device includes a filter and a filter having different pass bands, a detection unit, a processing unit, and a result output unit. The detection unit detects an electromagnetic wave from an object that is the target of identification through the filters. The pass band of the filters is designed to be suitable for object discrimination. The processing unit substitutes the output from the detection unit into a discrimination function determined based on the pass band of the filters and the teaching spectrum obtained in advance to infer the group which the object belongs to based on the substituted result.
    Type: Grant
    Filed: March 27, 2009
    Date of Patent: June 5, 2012
    Assignees: National University Corporation Toyohashi University of Technology, Sumitomo Electric Industries, Ltd.
    Inventors: Takashi Iwasaki, Masaharu Mogi, Shigeki Nakauchi
  • Patent number: 8193102
    Abstract: A method of assembling composite structures from objects in fluid includes providing a plurality of objects, each having a preselected size, shape, and spatial distribution of surface structural features characterizing a surface roughness; dispersing the objects into the fluid; and introducing a depletion agent. The depletion agent includes a plurality of particles having a size distribution preselected causing an attractive force arising from a depletion attraction between at least a first object and second object of the plurality in at least one relative position and orientation based on the preselected spatial distribution of surface structural features on the first and second objects, and the depletion attraction between the first and second objects forms at least one rigid bond or slippery bond at or proximate to respective surface portions based on the preselected spatial distribution of surface structural features on the first and second objects to form a two-object composite structure.
    Type: Grant
    Filed: November 14, 2008
    Date of Patent: June 5, 2012
    Assignee: The Regents of the University of California
    Inventors: Thomas G. Mason, Kun Zhao
  • Patent number: 8193497
    Abstract: Silicon photodetectors using near-infrared dipole antennas. The photodetectors include a silicon region formed on a semiconductor substrate, dipole antenna forming two arms that are spaced apart with the silicon region therebetween and inducing an electromagnetic wave signal of incident light, and electrodes disposed in a vertical direction of the dipole antenna and spaced apart with the silicon region therebetween, where a critical bias voltage is applied to the electrodes to induce an avalanche gain operation in the silicon region.
    Type: Grant
    Filed: February 12, 2010
    Date of Patent: June 5, 2012
    Assignees: Samsung Electronics Co., Ltd., The Board of Trustees of the Leland Stanford Junior University
    Inventors: Yoon-dong Park, David Andrew Barclay Miller, Young-gu Jin, In-sung Joe
  • Patent number: 8192734
    Abstract: The invention relates to methods of increasing bone strength in an animal, preferably a mammal. In one aspect, the methods provided by the invention involve administering to the animal strontium and a phytase enzyme. In another aspect, methods are provided for treating or preventing osteoporosis in a subject, the method comprising administering to said individual a phytase enzyme and strontium. Also encompassed are animal feed compositions comprising a phytase enzyme and supplemental strontium and a dietary supplement composition for administration to a human, the composition comprising a phytase enzyme and supplemental strontium.
    Type: Grant
    Filed: July 9, 2008
    Date of Patent: June 5, 2012
    Assignee: Cornell University
    Inventor: Xingen Lei
  • Patent number: 8195192
    Abstract: An portable tracking device integrating a mobile phone module (e.g. based on GSM or 3G networks), a GPS module, a radio Beacon and ultrasonic beacon. The tracking device is normally in a hibernated state when the entire device consumes little energy and require no periodically changing or recharging batteries to power the device. It consumes power from the primary battery only when a tracking process is actually taken place. With this portable tracking device on the person who is unable to affirmatively report his or her whereabout, the remote center and/or a search team can communicate the GPS module, radio beacon and ultrasonic beacon of the tracking device via the mobile phone module based on existing wireless communication technologies, such SMS, GPRS, ect, on GSM or 3 G networks, which also serves as a means of initial rough estimation of the tracking device's location.
    Type: Grant
    Filed: March 31, 2009
    Date of Patent: June 5, 2012
    Assignee: The Hong Kong Polytechnic University
    Inventors: Hoi Lam Martin Chow, Ching Ching Jenny Chung, Kam Yuk Claudia Lai, Hor Yau Carrie Lee, Kam Wah Ma, Ping See Diana Mak, Ping Kong Alexander Wai, Fuk Tat Arthur Mak, Jia Jane You, Kai Yu Tong, Yongping Zheng
  • Patent number: 8192263
    Abstract: A gaming machine according to the present invention includes: a gaming portion in which a plurality of main dice roll and stop; a timer capable of measuring time; a station having an input device with which a player can place a normal BET and a side BET different from the normal BET, and an image display capable of displaying an image; and a controller, the controller programmed to execute the processing of (A) starting acceptance of the normal BET and the side BET from the input device provided in the station, (B) measuring the time from when the acceptance was started in the processing (A) by using the timer, (C) terminating the acceptance of the normal BET and the side BET from the input device provided in the station, when the time measured in the processing (B) reaches a predetermined value, (D) determining whether or not the side BET has been placed by using the input device provided in the station, since the acceptance was started in the processing (A), (E) increasing the predetermined value when deter
    Type: Grant
    Filed: November 6, 2008
    Date of Patent: June 5, 2012
    Assignee: Universal Entertainment Corporation
    Inventor: Kazumasa Yoshizawa
  • Patent number: 8192714
    Abstract: A method for manufacturing carbon nanotubes of the present invention includes the steps of: preparing at least one metal selected from a group consisting of iron, cobalt and nickel and an organic compound: and forming carbon nanotubes by using the organic compound as a carbon source, wherein the metal and the organic compound are put into a heating vessel having a substance capable of converting electromagnetic energy into heat, and the organic compound is brought into contact with the metal in a state where the inside of the heating vessel is heated at a temperature of 600° C. to 900° C. by applying the electromagnetic energy to the heating vessel so as to form the carbon nanotubes.
    Type: Grant
    Filed: August 3, 2009
    Date of Patent: June 5, 2012
    Assignee: Shinshu University
    Inventors: Kazuchika Ohta, Ick-Soo Kim, Byoung-Suhk Kim, Jongchul Park
  • Patent number: 8192820
    Abstract: Optical information media containing a metal material layer and a carbon material layer are disclosed. The layering of the metal material layer and the carbon material layer are designed to reduce or eliminate problems associated with oxidation and berm formation during writing of data to the media.
    Type: Grant
    Filed: May 27, 2009
    Date of Patent: June 5, 2012
    Assignee: Brigham Young University
    Inventors: Matthew C. Asplund, Robert C. Davis, Douglas P. Hansen, Matthew R. Linford, Barry M. Lunt, Travis L. Niederhauser, Raymond T. Perkins, Mark O. Worthington
  • Patent number: 8193312
    Abstract: A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2, as do endogenous forms of BBP, and sequence conservation between species results in a variety of useful BBP compositions. BBP increases the over-all osteogenic activity of rhBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.
    Type: Grant
    Filed: November 16, 2007
    Date of Patent: June 5, 2012
    Assignees: The Regents of the University of California, The United States of America as represented by the Department of Veterans Affairs
    Inventors: Samuel S. Murray, Elsa J. Murray, Jeffrey C. Wang, Keyvan Behnam
  • Patent number: 8194307
    Abstract: A tunable acoustic gradient index of refraction (TAG) lens and system are provided that permit, in one aspect, dynamic selection of the lens output, including dynamic focusing and imaging. The system may include a TAG lens and at least one of a source and a detector of electromagnetic radiation. A controller may be provided in electrical communication with the lens and at least one of the source and detector and may be configured to provide a driving signal to control the index of refraction and to provide a synchronizing signal to time at least one of the source and the detector relative to the driving signal. Thus, the controller is able to specify that the source irradiates the lens (or detector detects the lens output) when a desired refractive index distribution is present within the lens, e.g. when a desired lens output is present.
    Type: Grant
    Filed: February 25, 2008
    Date of Patent: June 5, 2012
    Assignee: Trustees of Princeton University
    Inventors: Craig B. Arnold, Euan McLeod, Alexandre Mermillod-Blondin
  • Patent number: 8193377
    Abstract: (?)-EGCG, the most abundant catechin, was found to be chemopreventive and anticancer agent. However, (?)-EGCG has at least one limitation: it gives poor bioavailability. This invention provides compounds of generally formulae below, wherein R11, R12, R13, R21, R22, R2, R3, and R4 are each independently selected from the group consisting of —H, and C1 to C10 acyloxyl group; and R5 is selected from the group consisting of —H, C1-C10-alkyl, C2-C10-alkenyl, C2-C10-alkynyl, C3-C7-cycloalkyl, phenyl, benzyl and C3-C7-cycloalkenyl, whereas each of the last mentioned 7 groups can be substituted with any combination of one to six halogen atoms; at least one of R11, R12, R13, R21, R22, R2, R3 and R4 is —H, which were found to be more potent than their non-protected counterparts, which can be used as proteasome inhibitors to reduce tumor cell growth.
    Type: Grant
    Filed: August 15, 2005
    Date of Patent: June 5, 2012
    Assignees: The Hong Kong Polytechnic University, Wayne State University, University of South Florida
    Inventors: Tak-Hang Chan, Wai-Har Lam, Larry Ming-Cheung Chow, Qing Ping Dou, Deborah Joyce Kuhn, Aslamuzzaman Kazi, Sheng Biao Wan, Kristin R. Landis-Piwowar
  • Patent number: 8194930
    Abstract: An image processing apparatus and method for real time motion detection is provided. In the apparatus, a sub-sampling module receives and sub-samples a current image and a plurality of previous images and a census transform module performs census transform on each of the sub-sampled images to obtain a census vector. A correlation calculation module calculates and compares correlation values between the current image and the plurality of previous images and detects a region having highest correlation. A motion detection module tracks positions of pixels corresponding to the region having the highest correlation to detect motion information in the images. The image processing apparatus and method can obtain, in real time, the direction and speed of an object that is in motion in each image.
    Type: Grant
    Filed: December 1, 2008
    Date of Patent: June 5, 2012
    Assignee: Sungkyunkwan University Foundation For Corporate Collaboration
    Inventors: Jae Wook Jeon, Seung Hun Jin, Dong Kyun Kim, Ki Hoon Kim, Sang Jun Lee, Duc Dung Nguyen
  • Patent number: 8193360
    Abstract: Fluoroalkoxybenzamide compounds which selectively bind Sigma-2 receptors are disclosed. These compounds, when labelled with 18F, can be used as radiotracers for imaging of tumors by positron emission tomography (PET). In addition, these compounds, when labelled with 123I, can be used as radiotracers for imaging of tumors by single photon emission computed tomography (SPECT). Methods for synthesis of these compounds are also disclosed.
    Type: Grant
    Filed: April 7, 2011
    Date of Patent: June 5, 2012
    Assignee: Washington University
    Inventors: Robert H. Mach, Zhude Tu
  • Patent number: 8194635
    Abstract: An UpLink (UL) scheduling method and apparatus considering a characteristic of a power amplifier in a mobile communication terminal are provided. The UL scheduling method includes calculating a packet transmission time, which minimizes energy consumed in packet transmission, by using a Direct Current (DC) voltage used in a power amplifier for signal amplification and by using nonlinear amplification efficiency; and scheduling UL data by using the calculated packet transmission time.
    Type: Grant
    Filed: April 23, 2008
    Date of Patent: June 5, 2012
    Assignees: Samsung Electronics Co., Ltd., Seoul National University Industry Foundation
    Inventors: Sunghyun Choi, Kwang-Hun Han, Young-Kyu Choi, Yong-Hwan Lee
  • Patent number: 8192718
    Abstract: The invention relates to a method for treating disorders or diseases of a tight junction comprising delivering a pharmaceutical composition of nanoparticles to the tight junction, wherein the nanoparticles consist of positively charged chitosan, a negatively charged substrate, optionally a zero-charge compound, and at least one bioactive agent for treating said disorders or diseases of the tight junction of an animal subject.
    Type: Grant
    Filed: December 7, 2011
    Date of Patent: June 5, 2012
    Assignees: GP Medical, Inc., National Tsing Hua University
    Inventors: Hsing-Wen Sung, Kiran Sonaje, Ho-Ngoc Nguyen, Er-Yuan Chuang, Hosheng Tu
  • Patent number: 8192762
    Abstract: The present invention describes a method for synthesis of relatively low molecular weight imprinted polymers using living polymerization, and their application in analytical chemistry, pharmacology, medicine and the food industry. Specifically the low-molecular weight polymers are synthesized by the polymerization of functional monomers in the presence of a template, such as a biological receptor, enzyme, nucleic acid, cell, virus, microorganism, tissue sample or drug using living initiator. The conditions of living polymerization ensure a relatively small size of synthesized molecules. Synthesized in this way molecules (dimers, oligomers, polymers, or their mixture) have a higher affinity to the template than the original monomers and can rebind it in vitro and/or in vivo.
    Type: Grant
    Filed: June 1, 2006
    Date of Patent: June 5, 2012
    Assignee: Cranfield University
    Inventors: Khalku Karim, Sergey Anatoliyovich Piletsky, Olena Volodimirivna Piletska, Anthony Peter Francis Turner, Iva Chianella, Antonio Ricardo Leonardo Guerriero
  • Patent number: 8192947
    Abstract: The present invention is a novel biosensor composed of mOrange2 and mCherry fluorescent proteins operably linked via a linker, which provides a distinct color change upon separation of the fluorescent proteins.
    Type: Grant
    Filed: October 12, 2007
    Date of Patent: June 5, 2012
    Assignee: The Board of Trustees of the University of Illinois
    Inventors: Yingxiao Wang, Mingxing Ouyang
  • Patent number: 8193309
    Abstract: The present invention relates to a MUC1 cytoplasmic tail peptide or portion thereof. These peptides are useful for inducing an immune response to MUC1-expressing tumor cells and thus for preventing or treating cancer.
    Type: Grant
    Filed: January 29, 2010
    Date of Patent: June 5, 2012
    Assignee: Board of Regents of the University of Nebraska
    Inventors: Michael Anthony Hollingsworth, Karl Kohlgraf, Tom Caffrey