Abstract: A system for detecting and tracking a curvilinear object in a three-dimensional space includes an image acquisition system including a video camera arranged to acquire a video image of the curvilinear object and output a corresponding video signal, the video image comprising a plurality n of image frames each at a respective time ti, where i=1, 2, . . . , n; and a data processing system adapted to communicate with the image acquisition system to receive the video signal.

Abstract: Embodiments herein relate in vitro methods of stem cell differentiation into thyroid hormone producing cells and tissues, and methods of use of these cells.

Abstract: A method of selecting data, the method comprising, receiving data indicating a first requirement and identifying first records stored in a first database. The first records relate to first data subjects and the identification is based upon the first requirement. The first data subjects cannot be identified from the records of the first database. Second records are identified, the second records being stored in a second database and relating to the first data subjects. The first data subjects can be identified from the identified records of the second database. Each of the second records corresponds to a respective one of the first records, and the identification of the second records is based upon the first requirement.

Abstract: A user terminal includes a communication circuit, a certification circuit, an execution circuit, and a control circuit. The communication circuit receives a normal code of an application from an application providing server to install the application. The certification circuit receives a registration request message, which includes distinct information of a peripheral device, from the peripheral device storing a core code of the application, to certify the peripheral device, transmits a registration response message, which includes distinct information of the user terminal, to the peripheral device, and receives the core code of the application from the peripheral device. The execution circuit executes the application using the normal code and the core code. The control circuit restricts at least one of functions of the user terminal while the application is executed.

Abstract: According to one embodiment, a medical image diagnostic apparatus includes an X-ray tube, X-ray detector, image generation circuitry, display, and correction circuitry. The X-ray tube generates X-rays to an object. The X-ray detector detects the X-rays. The image generation circuitry generate an X-ray image based on the detected X-rays. The display displays an incident dose of the X-rays on the object, on an object image indicating the object. The correction circuitry correct a relative positional relationship between the object image and a display area of the incident dose on the object image based on the X-ray image.

Abstract: A method for inhibition of leukemic stem cells expressing IL-3R? (CD123), comprises contacting the cells with an antigen binding molecule comprising a Fc region or a modified Fc region having enhanced Fc effector function, wherein the antigen binding molecule binds selectively to IL-3R? (CD123). The invention includes the treatment of a hematologic cancer condition in a patient by administration to the patient of an effective amount of the antigen binding molecule.

Abstract: The purpose of the present invention is to provide an anticancer agent for potentiating an antitumor effect, alleviating side effects, and further extending the survival rate by concomitant use with a component having an anticancer effect. An anticancer agent combining arctigenin and a component other than arctigenin that has an anticancer effect, in which the anticancer agent may be a combination drug or may be a kit configured from a formulation containing arctigenin and a formulation containing a component that has an anticancer effect, and the concomitant use of arctigenin and the component having an anticancer effect more strongly inhibits tumor growth and reduces the proportion of cancer stem cells in the tumor, making it possible to extend the total survival time and to alleviate side effects caused by the component having an anticancer effect.

Abstract: A pharmaceutical composition and method for treating brain cancer are provided. The method includes administering to a patient in need thereof an effective amount of one or more compounds that include moclobemide, clorgyline, clorgyline's Near-infra-red dye Monoamine Oxidase Inhibitor (NMI), and MHI 148-clorgyline, and their salt thereof. The composition and method are particularly effective in reducing the size of glioblastomas that are temozolomide (TMZ) resistant.

Abstract: A transducer in the form of cloth having high flexibility obtained by manufacturing a conventional woven or knitted fabric structure using general-purpose fiber materials. The transducer includes piezoelectric units, each including two conductive fibers and one piezoelectric fiber arranged substantially on the same plane in the order of the conductive fiber, the piezoelectric fiber and the conductive fiber, and outputs and inputs an electric signal.

Abstract: The present disclosure relates to methods, devices, and systems used for the treatment of and/or promoting recovery from various neurological disorders and conditions, including epilepsy and other seizure disorders and movement and other related disorders; for promoting recovery from acute or chronic brain injury (e.g. stroke, hypoxia/ischemia, head trauma, subarachnoid hemorrhage, and other forms of brain injury, for awakening and/or promoting the recovery of patients in various levels of coma, altered mental status or vegetative state); or for promoting recovery from chronic daily headache and migraine and related disorders via external (cutaneous) stimulation of the sensory branches of the trigeminal nerve in the face and forehead. More specifically, devices and electrode assemblies configured for stimulation of the supraorbital, supratrochlear, infraorbital, auriculotemporal, zygomaticotemporal, zygomaticoorbital, zygomaticofacial, nasal and infratrochlear nerves are disclosed.

Abstract: The direct current (DC) side fault isolator for high voltage direct current (HVDC) converters (10) includes a first set of double thyristor switches (12) connected across the line-to-line voltage terminals between first and second phases of alternating current (AC) terminals of a HVDC converter (14), and a second set of double thyristor switches (12) connected across the line-to-line voltage between the second phase and a third phase of the AC terminals of the HVDC converter (14). In use, the first and second sets of double thyristor switches (12) separate the HVDC converter (10) from an external power grid (18) during direct current (DC) side faults by turning on these thyristors (12).

Abstract: The present invention provides an alloy for medical use including an Au—Pt alloy, in which the Au—Pt alloy has a Pt concentration of 24 mass % or more and less than 34 mass % with the balance being Au, and has at least a material structure in which a Pt-rich phase having a Pt concentration higher than that of an ?-phase is distributed in an ?-phase matrix, the Pt-rich phase has a Pt concentration that is 1.2 to 3.8 times the Pt concentration of the ?-phase, and the Pt-rich phase has an area ratio of 1 to 22% in any cross-section. This alloy is an artifact-free alloy material that exhibits excellent compatibility with a magnetic field environment such as an MRI and has magnetic susceptibility of ±4 ppm with respect to magnetic susceptibility of water.

Abstract: The present disclosure provides proteins comprising antibody antigen binding domains that bind to Fn14 and uses thereof. The present disclosure also provides methods for treating wasting disorders, such as cachexia.

Abstract: The invention provides a method for screening for and detection of solid organ graft rejection in a subject that comprises assaying a patient sample of plasma, serum or blood from the subject for a protein marker identified herein. An elevated or reduced amount of marker present in the patient sample compared to a control sample is indicative of rejection, and identifies subjects in need of biopsy or modified treatment. The method can be used to screen for patients in danger of transplant rejection without having to undergo more costly, risky and invasive biopsy procedures.

Abstract: Disclosed is a method for determining alcohol consumption capable of analyzing alcohol consumption in a time domain by analyzing a formant slope of a voice signal, and a recording medium and a terminal for carrying out same. An terminal for determining whether a person is drunk comprises: a voice input unit for generating a voice frame by receiving a voice signal; a voiced/unvoiced sound analysis unit for determining whether a received voiced frame corresponds to a voiced sound; a formant frequency extraction unit for extracting a plurality of formant frequencies of the voice frame corresponding to the voiced sound; and an alcohol consumption determining unit for calculating a formant slope between the plurality of formant frequencies, and determining the state of alcohol consumption depending on the formant slope, thereby determining whether a person is drunk by analyzing the formant slope of an inputted voice.

Abstract: A cooling device with small structured rib-dimple hybrid structures, comprising a substrate, a cooling channel, a plurality of small structured ribs and a plurality of dimples. The cooling channel, the plurality of small structured ribs and the plurality of dimples are all disposed on the wall surface of the substrate; the plurality of dimples are in a staggered arrangement or in a longitudinal arrangement, forming a dimple array; an upstream wall surface of each dimple or a plurality of dimples is provided with the small structured ribs, thus forming an small structured rib-dimple hybrid structure.

Abstract: A living body state estimation apparatus acquires information indicating a state of a living body. The living body state estimation apparatus is configured to include an electrocardiogram signal acquisition unit which acquires an electrocardiogram signal of the living body and an information acquisition unit which acquires a parameter as the information, the parameter specifying a predetermined function indicating a probability distribution for a reference wave interval which is a time interval between peaks of consecutive predetermined reference waves in the acquired electrocardiogram signal.

Abstract: The present disclosure relates to aqueous all-copper redox flow batteries. This battery comprises at least one first and second half-cell compartments including the first and second aqueous electrolyte solutions comprising a copper compound and supporting electrolytes and a first and second electrodes. The battery further comprises external storage tanks for the electrolytes residing outside of the half-cell compartments, and means for circulating the electrolytes to and from the half-cells. There is a separator between the first and the second half-cell, and the half-cells of this battery are configured to conduct oxidation and reduction reactions for charging and discharging the battery.

Abstract: The present invention provides compositions and methods of use pertaining to rAAV-mediated delivery of therapeutically effective molecules for treatment of diseases such as Pompe disease. These compositions in combination with various routes and methods of administration result in targeted expression of therapeutic molecules in specific organs, tissues and cells.

Abstract: Disclosed is a drug delivery implant implanted into a bone. The drug delivery implant includes an implant fixture provided with an inlet formed at the upper end thereof and a drug supply cartridge coupled to the fixture, the drug supply cartridge includes a cap to close the inlet of the fixture and a cartridge main body provided under the cap, coupled with the cap and accommodated in the fixture to release a drug, and a cartridge hole to accommodate the cartridge main body and drug channels to guide the drug released from the inside of the cartridge main body to the outside of the fixture are formed in the fixture. The drug delivery implant may continuously administer the drug into bone tissues and mount the drug cartridge together with the cap in the fixture, thus facilitating mount of the drug cartridge in the fixture and replacement of the drug cartridge.