Abstract: A method of fabricating a 3D porous electrode architecture comprises forming a microbattery template that includes (a) a lattice structure comprising a first lattice portion separated from a second lattice portion on a substrate, and (b) a solid structure on the substrate including a separating portion between the first and second lattice portions. Interstices of the first lattice portion are infiltrated with a first conductive material and interstices of the second lattice portion are infiltrated with a second conductive material. Each of the first and second conductive materials fill the interstices to reach a predetermined thickness on the substrate. The solid structure and the lattice structure are removed from the structure, thereby forming first and second conductive scaffolds comprising a porosity defined by the lattice structure and having a lateral size and shape defined by walls of the solid structure.

Abstract: A print scheduling and processing method, apparatus and system are disclosed. Embodiments of the invention adopt such a method that at least one print processing apparatus satisfying a print requirement of a user is determined; upon reception of a print request sent from an idle print processing apparatus, the idle print processing apparatus sending the print request is notified of a print task of the user if it is determined that the idle print processing apparatus is included among the at least one print processing apparatus satisfying the print requirement of the user.

Abstract: A paraxial cloaking device provides a cloaking volume in which an item can be hid from view. A cloaking device includes an optical input receiving light rays and an optical output from which a continuous range of directions of the received light rays exit the paraxial cloaking device. The cloaking volume being disposed between the optical input and the optical output. For received light rays having incoming directions non-parallel to the reference optical axis up to a first angle, each of the received light rays exits the cloaking device substantially aligned with the respective received light ray and does not pass through the cloaking volume. The paraxial cloaking device has a unity magnification factor. In some instances, the paraxial cloaking device includes a phase matching element.

Abstract: Disclosed are glucose-sensitive nanoparticles which includes a phenylboronic acid derivative and a biocompatible polymer, and is prepared as an amphiphilic conjugate having chemical binding between the phenylboronic acid derivative and the biocompatible polymer. The use of the composition can effectively collect glucose in the cancer tissue, thereby simultaneously performing diagnosis and therapy of cancer.

Abstract: In various embodiments, tools, strategies, and techniques are provided for analyzing student performance and learning activity to facilitate enhancing the student experience in different learning environments. A learning analysis system can be provided that uses a statistical analysis framework for making inferences about the level of learning of both individual students and classes of multiple students in association with different knowledge components included in a learning domain.

Abstract: Disclosed are an anti-human TIM-3 antibody having high ADCC activity or antibody fragment thereof by screening a monoclonal antibody or antibody fragment thereof which binds to the amino acid sequence of the extracellular region of TIM-3 or its three-dimensional structure and exhibits ADCC activity; a hybridoma which produces the antibody; a DNA encoding the antibody; a vector comprising the DNA; a transformant which is obtainable by introducing the vector; a method for producing the antibody or the antibody fragment thereof which comprises using the hybridoma or the transformant; and a therapeutic agent and a diagnostic agent comprising the antibody or the antibody fragment thereof as an active ingredient.

Abstract: C-terminal endostatin polypeptides are disclosed herein. Polynucleotides encoding these polypeptide, host cells transformed with the polynucleotides, and methods of using these polypeptides and polynucleotides are disclosed. Uses of these polypeptide, polynucleotides and expression vectors include the treatment of fibrosis in a subject. Thus, methods are provided for treating fibrosis, including fibrosis of the skin and/or the lung.

Abstract: The present invention relates to composite materials with a high dielectric constant and high dielectric strength and to methods of producing the composite materials. The composite materials have high dielectric constants at a range of high frequencies and possess robust mechanical properties and strengths, such that they may be machined to a variety of configurations. The composite materials also have high dielectric strengths for operation in high power and high energy density systems. In one embodiment, the composite material is composed of a trimodal distribution of ceramic particles, including barium titanate, barium strontium titanate (BST), or combinations thereof and a polymer binder.

Abstract: This invention provides a compound having the structure wherein ?, ?, X, Y, and R1-R11 are defined herein. This invention also provides a pharmaceutical composition comprising the above compounds, a method of inhibiting the activity and/or levels of a matrix metalloproteinase (MMP), a method of inhibiting the production of a cytokine in a population of cells, a method of inhibiting the production of a growth factor in a population of cells, and a method of inhibiting NF?-B activation in a population of cells.

Abstract: A system for detecting object movement including a sensory network having at least one sensory device using modulated radar for detecting an object in proximity to the sensory network. The sensory network including a wireless transmission system and a base station having a computer processing system located remote from the sensory network and including a wireless transmission system to communicate with the sensory network. The base station having a computer readable program code for causing the computer processing system to analyze data received from the sensory network to determine motion characteristics of the object in proximity to the sensory network.

Abstract: The invention relates to novel artificial antigen presenting cells (aAPCs). The aAPC comprises at least one stimulatory ligand and at least one co-stimulatory ligand where the ligands each specifically bind with a cognate molecule on a T cell of interest, thereby mediating expansion of the T cell. The aAPC of the invention can further comprise additional molecules useful for expanding a T cell of interest. The aAPC of the invention can be used as an “off the shelf” APC that can be readily designed to expand a T cell of interest. Also, the aAPC of the invention can be used identify the stimulatory, co-stimulatory, and any other factors that mediate growth and expansion of a T cell of interest. Thus, the present invention provides powerful tools for development of novel therapeutics where activation and expansion of a T cell can provide a benefit.

Abstract: Disclosed herein are polymer-coated iron oxide magnetic nanoparticles and methods of their manufacture and use. The nanoparticles are coated with a copolymer of poly(maleic anhydride alt-H2C?CH—R1)-polyethylene glycol (PMAR-PEG), wherein R1 is a hydrophobic moiety. The molecular weights of the PMAR and PEG portions of the copolymer, as well as the core diameter of the nanoparticles are selected in order to produce optimal performance for specific applications. Representative applications of the nanoparticles include magnetic particle imaging, magnetic sentinel lymph node biopsy, and magnetic fluid hyperthermia. The disclosed nanoparticles are tools for these methods that provide previously unachieved levels of stability (e.g., via reduced agglomeration) and customizability (e.g., tuned blood circulation half-life in vivo).

Abstract: Embodiments include methods, systems, and/or devices that may be used to image, obtain three-dimensional information from a scence, and/or locate multiple small particles and/or objects in three dimensions. A point spread function (PSF) with a predefined three dimensional shape may be implemented to obtain high Fisher information in 3D. The PSF may be generated via a phase mask, an amplitude mask, a hologram, or a diffractive optical element. The small particles may be imaged using the 3D PSF. The images may be used to find the precise location of the object using an estimation algorithm such as maximum likelihood estimation (MLE), expectation maximization, or Bayesian methods, for example. Calibration measurements can be used to improve the theoretical model of the optical system. Fiduciary particles/targets can also be used to compensate for drift and other type of movement of the sample relative to the detector.

Abstract: The present invention includes a method of delivering a therapeutic agent into and across an endothelial cell (EC) in a subject in need thereof, comprising: attaching to a T Cell receptor mimic (TCR mimic) an active agent to form a therapeutic agent; and administering to the subject the therapeutic agent in a pharmaceutically acceptable carrier, wherein the therapeutic agent effectively crosses the EC microvascular barrier. Furthermore, the present invention relates to methods of treating diseases (particularly neuronal diseases) or conditions comprising identifying a subject in need of such a treatment and administering to said subject a composition comprising a TCR mimic conjugated to an active agent.

Abstract: Cooperative caching systems incorporating Plug-and-Play base stations are described herein. Plug-and-Play base stations with large caching capacities are employed in a wireless network to perform cooperative transmission with macro base stations. Each Plug-and-Play base station can either have wireless backhaul or a low-cost wired backhaul connection to the macro base stations. Cooperative caching systems can direct traffic between the Plug-and-Play base stations and the macro base stations.

Abstract: A method comprises: generating a first and a second correlated photon beam with wavelengths ?1 and ?2, respectively, wherein preferably ?1??2; separating the first photon beam and the second photon beam; illuminating an object with the first photon beam; generating a third and a fourth correlated photon beam with wavelength ?1 and wavelength ?2, respectively; overlapping the first photon beam with the third photon beam such that photons of wavelength ?1 in either photon beam are indistinguishable; overlapping the second photon beam with the fourth photon beam such that photons of wavelength ?2 in either photon beam are indistinguishable; and using the overlapped photons of wavelength ?2 for imaging and/or spectroscopy of the object such that the photons that illuminate the object are not detected.

Abstract: The present invention provides an isolated nucleic acid molecule containing a repeat region of an isolated spinocerebellar ataxia type 8 (SCA8) coding sequence, the coding sequence located within the long arm of chromosome 13, and the complement of the nucleic acid molecule. Diagnostic methods based on identification of this repeat region are also provided.

Abstract: Cell tubes that can be used both for pathology collection and subsequent cell processing include a tube with a cell bed at a lower portion of the tube. The tube can include a base member that can be detachable from the tube body. The tubes can be used to form cell (cytology) blocks that incorporate the cell bed. The cell bed can be an inert cell bed of paraffin.

Abstract: An envelope tracking power amplifier is disclosed herein. The envelope tracking power amplifier includes a multi-mode bias modulator and a power amplifier. The multi-mode bias modulator generates an envelope-modulated bias voltage from the envelope signal of an radio frequency (RF) signal whose power is to be amplified by using a linear amplifier and a switching amplifier each having varying current driving capability in response to an operation mode control signal that determines any one of low-level mode and high-level mode. The power amplifier is biased in response to the envelope-modulated bias voltage, amplifies the RF signal, and outputs the amplified RF signal to an antenna.

Abstract: Described herein are systems for manipulating a flowable substance, comprising: a flowable substance; a heating means; a cooling means; and a composition comprising chemically inert particles coated with a stimuli-responsive material. Compositions and methods for using the compositions are also described herein.