Patents Assigned to University
  • Method and apparatus for an integrated capacitor
    Patent number: 9559158
    Abstract: An integrated capacitor can be fabricated with both electrodes formed by trenches for low resistance. According to one embodiment, the capacitor can comprise a first trench electrode, one or more dielectric layers, and a second trench electrode. The first trench electrode and the second trench electrode can be fabricated in different trenches to improve capacitance density and resistance of the integrated capacitor.
    Type: Grant
    Filed: January 8, 2016
    Date of Patent: January 31, 2017
    Assignee: THE HONG KONG UNIVERSITY OF SCIENCE AND TECHNOLOGY
    Inventors: Kin On Johnny Sin, Rongxiang Wu, Xiangming Fang
  • Carbon nanotube composite layer
    Patent number: 9559319
    Abstract: A carbon nanotube composite layer includes a number of semiconductor particles and a number of carbon nanotubes. The number of semiconductor particles are dispersed into the number of carbon nanotubes, the number of carbon nanotubes and the number of semiconductor particles are electrically connected with each other, each of the number of semiconductor particles includes a semiconductor fragment, the semiconductor fragment includes a number of semiconductor molecular layers stacked together, a number of the number of semiconductor molecular layers ranges from about 1 to about 20, an area of the semiconductor fragment ranges from about 0.1 square micrometers to about 5 square micrometers, and a thickness of the semiconductor fragment range from about 2 nanometers to about 20 nanometers.
    Type: Grant
    Filed: April 22, 2015
    Date of Patent: January 31, 2017
    Assignees: Tsinghua University, HON HAI PRECISION INDUSTRY CO., LTD.
    Inventors: Yuan-Hao Jin, Qun-Qing Li, Shou-Shan Fan
  • Mach-Zehnder interferometer having a doubly-corrugated spoofed surface plasmon polariton waveguide
    Patent number: 9557223
    Abstract: A Mach-Zehnder interferometer (MZI) structure based on a doubly-corrugated spoofed surface plasmon polariton (DC-SSPP) waveguide is presented. The dependence of phase change on the dielectric loading of the DC-SSPP structure causes the output from both arms to interfere and enhance features on the transmission spectrum of the MZI. The proposed MZI structure can be used for tag-free bio-molecular sensing. The highly localized electro-magnetic field at frequencies close to SSPP resonance is shown to reduce the sample amount needed to produce interference patterns without affecting the selectivity of the sensing structure.
    Type: Grant
    Filed: June 26, 2014
    Date of Patent: January 31, 2017
    Assignee: The Regents Of The University Of Michigan
    Inventors: Pinaki Mazumder, Zhao Xu, Kyungjun Song
  • Method of making calcium-fluoride layer formed on an object surface for more wear resistance
    Patent number: 9554882
    Abstract: A method of making a calcium-fluoride layer formed on an object surface for more wear resistance includes the steps of coating sodium fluoride to a surface of an object having calcium, whereby the calcium fluoride and the calcium are inverted to become a calcium-fluoride layer on the surface of the object after a chemistry reaction; preparing a CO2 laser device having a CO2 laser emitter for emitting CO2 laser; and applying irradiation of the CO2 laser via the CO2 laser emitter to the calcium-fluoride layer for at least five seconds. In light of this, the wear resistance of the calcium-fluoride layer is enhanced for at least 34%, the absorption rate of the fluoride is increased for at least 23%, and the surface of the object has aesthetic and integral appearance.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: January 31, 2017
    Assignee: NATIONAL CHUNG CHENG UNIVERSITY
    Inventors: Yeau-Ren Jeng, Tsung-Ting Lin, Yu-Xian Huang, Dar-Bin Shieh
  • Therapeutic uses of selected pyrazolopyrimidine compounds with anti-Mer tyrosine kinase activity
    Patent number: 9555030
    Abstract: Pyrazolopyrimidine compounds, methods of use, and processes for making compounds with anti-Mer tyrosine kinase activity comprising Formula I, II, III, IV, or a pharmaceutically acceptable composition, salt, isotopic analog, or prodrug thereof, are provided. The pyrazolopyrimidine compounds described herein have Mer tyrosine kinase (MerTK) inhibitory activity and are useful as anti-infective agents, immunostimulatory and immunomodulatory agents, anti-cancer agents (including against MerTK ?/? tumors and ITD and TKD mutant forms of Acute Myeloid Leukemia (AML)), and as adjunctive agents in combination with chemotherapeutic, radiation or other standard of care for neoplasms.
    Type: Grant
    Filed: April 3, 2015
    Date of Patent: January 31, 2017
    Assignee: The University of North Carolina at Chapel Hill
    Inventors: Xiaodong Wang, Stephen Frye
  • Optical lens and lighting device
    Patent number: 9557099
    Abstract: An optical lens for a light source has an incidence surface receiving light rays emitted from a light source and an aspherical emitting surface optically coupled with the incidence surface for receiving light rays from the incidence surface and emitting light rays received from the incidence surface. The incidence surface defines a cavity for receiving the light source. An opaque or semi-opaque bottom surface adjoins the incidence surface and emitting surface. A lighting device has a substrate, a lighting source located on the substrate, and the optical lens located with the substrate and enclosing the lighting device. A strip light has an elongate substrate having light sources and respective lenses distributed longitudinally along the substrate. Such a strip light using the lens is suitable for lighting the interior of a commercial or domestic refrigerator, chillier cabinet, or other enclosure.
    Type: Grant
    Filed: April 25, 2014
    Date of Patent: January 31, 2017
    Assignee: THE HONG KONG POLYTECHNIC UNIVERSITY
    Inventors: Bo Wang, Suet To, Ka Chun Cheung, Wen Kui Wang
  • Allosteric modulators of CB1 cannabinoid receptors
    Patent number: 9556118
    Abstract: The present invention relates to novel heterocyclic derivatives which are allosteric modulators of cannabinoid receptor 1 (CB1) and which are useful for the treatment or prevention of neurological and psychiatric disorders associated with endocannabinoid dysfunction and diseases in which the CB1 subtype of cannabinoid receptor is involved; to processes for their preparation; to pharmaceutical compositions comprising them; and to methods of using them.
    Type: Grant
    Filed: July 3, 2014
    Date of Patent: January 31, 2017
    Assignee: Northeastern University
    Inventors: Ganeshsingh A. Thakur, Pushkar M. Kulkarni
  • Three dimensional display system
    Patent number: 9557573
    Abstract: A light emitting device is presented. The device comprises an array of pixels and an electrode arrangement, wherein said array of pixels comprises pixels of first and second groups comprising first and second pluralities of light emitting nanorods aligned along first and second predetermined axes respectively, the axes being substantially perpendicular to each other, and the pixels of said array are associated with a plurality of electrode elements of said electrode arrangement thereby enabling modulation of optical emission of one or more pixels separately from one or more other pixels of said pixel array by controllable application of an electric field, the device being therefore configured and operable as an active pixel emitter.
    Type: Grant
    Filed: May 9, 2012
    Date of Patent: January 31, 2017
    Assignees: Merck Patent GmbH, Yissum Research Development Company of the Hebrew University of Jerusalem, Ltd., Qlight Nanotech, Ltd.
    Inventors: Volker Hilarius, Nadja Velesco, Uri Banin, Hagai Arbell, Serge Velesco
  • Neuregulin antagonists and use thereof in treating cancer
    Patent number: 9556249
    Abstract: The invention provides neuregulin antagonists and methods of using the neuregulin antagonists in delaying the time to tumor recurrence or preventing resistance of cancer cells to treatment with a therapeutic agent.
    Type: Grant
    Filed: February 17, 2011
    Date of Patent: January 31, 2017
    Assignees: Genentech, Inc., The Board of Trustees of the Leland Stanford Junior University
    Inventors: Erica Jackson, Eric Alejandro Sweet-Cordero
  • Anti-angiogenic molecules, nanostructures and uses thereof
    Patent number: 9556232
    Abstract: The disclosure is generally directed toward the design and synthesis of peptide amphiphile (PA) molecules that comprises a peptide configured to inhibit angiogenesis. The peptide amphiphile comprises a hydrophobic tail, peptide sequence capable of beta-sheet formation; and a peptide, wherein the peptide is configured to inhibit angiogenesis. Optionally the PA further comprises a flexible linker between the peptide sequence capable of beta-sheet formation and the peptides. Further this disclosure is directed to nanostructures comprising peptide amphiphiles configured to inhibit angiogenesis.
    Type: Grant
    Filed: October 27, 2015
    Date of Patent: January 31, 2017
    Assignee: Northwestern University
    Inventors: Runye H. Zha, Ming Zhang, Samuel I. Stupp
  • Steady hand micromanipulation robot
    Patent number: 9554865
    Abstract: A cooperative-control robot includes a base component, a mobile platform arranged proximate the base component, a translation assembly operatively connected to the base component and the mobile platform and configured to move the mobile platform with translational degrees of freedom substantially without rotation with respect to said the component, a tool assembly connected to the mobile platform, and a control system configured to communicate with the translation assembly to control motion of the mobile platform in response to forces by a user applied to at least a portion of the cooperative-control robot. The translation assembly includes at least three independently operable actuator arms, each connected to a separate position of the mobile platform. A robotic system includes two or more the cooperative-control robots.
    Type: Grant
    Filed: November 13, 2014
    Date of Patent: January 31, 2017
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Kevin C. Olds, Russell H. Taylor
  • Formulation of active agent loaded activated PLGA nanoparticles for targeted cancer nano-therapeutics
    Patent number: 9555011
    Abstract: The present invention includes compositions and methods of making an activated polymeric nanoparticle for targeted drug delivery that includes a biocompatible polymer and an amphiphilic stabilizing agent non-covalently associated with a spacer compound that includes at least one electrophile that selectively reacts with any nucleophilic on a targeting agent and places the targeting agent on the exterior surface of a biodegradable nanoshell, wherein an active agent is loaded with the nanoshell.
    Type: Grant
    Filed: April 7, 2015
    Date of Patent: January 31, 2017
    Assignee: University of North Texas Health Science Center at Fort Worth
    Inventors: Arthur R. C. Braden, Jamboor K. Vishwanatha
  • Door checker for vehicle
    Patent number: 9556658
    Abstract: A door checker for a vehicle includes a hinge rotatably connecting a door to a vehicle body and having a shaft, a slider penetratingly inserted into the shaft and linearly moving with rotational force of the shaft, and a checking unit linearly reciprocating in a radial direction of the shaft by the slider. By implementing a manipulation feeling in opening and closing a door by increasing a section for checking the door by converting a rotational movement of the door into a linear movement based on a screw principle, operability can be improved to enhance marketability, and durability can be enhanced by increasing the section for implementing operating force for opening and closing a door.
    Type: Grant
    Filed: December 15, 2014
    Date of Patent: January 31, 2017
    Assignees: Hyundai Motor Company, Pusan National University Industry—University Cooperation Foundation
    Inventors: Yoong Ho Jung, Hyung Don Kim, Sung Min Son
  • Conjugate of a metal nanoparticle and a light emitting material
    Patent number: 9557324
    Abstract: Disclosed are a conjugate of a metal nanoparticle including a magnetic core and at least one light emitting material linked to the metal nanoparticle through a linker, wherein the linker has an affinity for a biological material and has changed structure after contacting a biological material, a biosensor including the conjugate, and a method of measuring a concentration of specific biological material in a biological sample using the conjugate or the biosensor.
    Type: Grant
    Filed: February 19, 2014
    Date of Patent: January 31, 2017
    Assignees: SAMSUNG ELECTRONICS., LTD., THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Shin Ae Jun, Dae ha Seo, Eun Joo Jang, Young-Wook Jun
  • Amorphous steel composites with enhanced strengths, elastic properties and ductilities
    Patent number: 9555467
    Abstract: Amorphous steel composites with enhanced mechanical properties and related methods for toughening amorphous steel alloys. The composites are formed from monolithic amorphous steel and hard ceramic particulates, which must be embedded in the glass matrix through melting at a temperature above the melting point for the steel but below the melting point for the ceramic. The ceramics may be carbides, nitrides, borides, iron-refractory carbides, or iron-refractory borides. The produced composites may be one of two types, primarily distinguished by the methods for embedding the ceramic particulates in the steel. These methods may be applied to a variety of amorphous steels as well as other non-ferrous amorphous metals, and the resulting composites can be used in various applications and utilizations.
    Type: Grant
    Filed: May 18, 2015
    Date of Patent: January 31, 2017
    Assignee: University of Virginia Patent Foundation
    Inventors: S. Joseph Poon, Gary J. Shiflet, Xiao-Jun Gu
  • Synthesis and analysis of compounds capable of inducing differentiation of human mesenchymal stems cells into hepatocytes
    Patent number: 9555061
    Abstract: The invention relates to low-molecular-weight compounds which are capable of inducing differentiation of mesenchymal stem cell into hepatocytes.
    Type: Grant
    Filed: April 2, 2012
    Date of Patent: January 31, 2017
    Assignees: National University Corporation Torrori University, Tokyo Women's Medical University
    Inventors: Goshi Shiota, Yoshiko Hoshikawa, Noriko Matsumoto, Yoshiaki Matsumi, Minoru Morimoto, Takayuki Tonoi, Hiroyuki Saimoto, Kazuo Ohashi, Teruo Okano
  • Carboxylic acid ester prodrug inhibitors of MEK
    Patent number: 9556112
    Abstract: The invention generally relates to compounds having structure I: wherein x represents alkyl, aryl or het-aryl, each of y independently represents hydrogen or halogen and z represents hydrogen or alkyl. Further, said compounds are inhibitors of MEK 1, 2 and 5. Furthermore, the invention includes methods of making said compounds, compositions including said compounds and uses for inhibiting MEK 1, 2 and 5.
    Type: Grant
    Filed: November 15, 2013
    Date of Patent: January 31, 2017
    Assignee: Duquesne University of the Holy Ghost
    Inventors: Suravi Chakrabarty, Darlene Monlish, Patrick Flaherty, Jane E. Cavanaugh, Sneha Potdar
  • Histogram of hosoya index (HoH) features for quantitative histomorphometry
    Patent number: 9558394
    Abstract: Methods, apparatus, and other embodiments associated with classifying a region of cancerous tissue using a Histogram of Hosoya are described. One example apparatus includes a set of logics that acquires an image of a region of tissue demonstrating cancerous pathology, constructs a cell graph of the region of tissue, decomposes the cell graph into a set of subgraphs, computes a Hosoya Index for a subgraph, constructs a Histogram of Hosoya for the image based on the distribution of the subgraphs, and classifies the image based on the Histogram of Hosoya. Embodiments of example apparatus may generate and display the Histogram of Hosoya for the image. A prognosis for the patient may be provided based on the distribution of the histogram.
    Type: Grant
    Filed: January 20, 2015
    Date of Patent: January 31, 2017
    Assignee: Case Western Reserve University
    Inventors: Anant Madabhushi, Ajay Basavanhally, Sahirzeeshan Ali
  • Treatment for pancreatic cancer
    Patent number: 9555042
    Abstract: The invention is related to a method of treating a subject with pancreatic cancer with administration of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: October 3, 2014
    Date of Patent: January 31, 2017
    Assignee: University Health Network
    Inventors: David W. Hedley, Ines Lohse, Jacqueline M. Mason, Mark R. Bray
  • Polymer carrier
    Patent number: 9554997
    Abstract: Compositions and methods for delivering bioactive agents, such as vitamins, hormones, nutrients and drugs, by stabilizing and or solubilizing these agents in a polymer matrix. The carrier polymers can be used in drug delivery and are useful for delivery of small molecules. The carrier polymers also can be used in scaffolds for regenerative medicine.
    Type: Grant
    Filed: June 18, 2008
    Date of Patent: January 31, 2017
    Assignee: New York University
    Inventors: Jin Kim Montclare, Man Xia Lee, Jennifer Haghpanah