Abstract: The present invention provides pharmaceutical compositions composing, as an active ingredient, a substance capable of activating the ? chain of Fc receptors (FcR?) (provided that the substance is not an immunoglobulin for intravenous injection), and agents for stimulating myelinogenesis. The invention also provides agents for stimulating the differentiation of oligodendroglial precursor cells, agents for activating Fyn tyrosine kinase, and agents for stimulating the expression of myelin basic protein, all comprising a substance capable of activating FcR? as an active ingredient. Further, the invention provides a method of detecting myelinogenetic oligodendroglias or precursor cells thereof which comprises using the expression of FcR? in oligodendroglias or precursor cells thereof as an indicator.

Abstract: Provided are a method of preparing a zinc silicate-based phosphor and a zinc silicate-based phosphor prepared using the method. The method includes: (a) preparing a solution including a Zn precursor compound and a Si precursor compound; (b) adding a coprecipitant to the solution to form precipitation; and (c) heat treating the solution in which the precipitation is formed to synthesize zinc silicate (Zn2SiO4), wherein a solvent of the solution including the Zn precursor compound and the Si precursor compound includes at least one selected from the group consisting of ethanol, methanol, 1-propanol, 2-propanol, 1-butanol, 2-butanol, 1-pentanol, 2-pentanol, 3-pentanol, 1-hexanol, and 1-heptanol, and hydrazine is used as the coprecipitant.

Abstract: The core metal of a protein such as ferritin is used as a nucleus for crystallizing a silicone thin film and then the thus crystallized film is employed in the channel part of a thin-film transistor. By aligning the protein on the surface of amorphous silicone and heating, the crystallinity is controlled. In the case of ferritin, the core diameter of the protein is 7 mm. That is, this protein is highly even in size (i.e., the metal content). Thus, the amount of the protein to be deposited on the amorphous silicone surface can be accurately controlled by controlling the protein core density. Furthermore, the type of the core metal can be altered by chemical reactions and the above method is applicable not only to amorphous silicone but also to amorphous films of various types such as germanium. Thus, the amount of nickel required in crystallization is controlled by using a protein. Moreover, the distribution density of the nickel core is controlled to thereby conduct crystallization at a desired crystal size.

Abstract: Single ion conductors comprising polymer electrolytes prepared by grafting a salt compound onto a comb-branch polymer or dendrimer are disclosed having superior properties.

Abstract: In tensor MRI, a set of k-space MRI data points is acquired that includes one or more k-space subsets of MRI data points. An object orientation (or spatial transformation) corresponding to each of the k-space subsets is determined. Because the object orientation (or spatial transformation) can differ from subset to subset, the overall set of k-space data can be inconsistent with respect to object orientation (or spatial transformation). This possible inconsistency can be addressed by providing a k-space tensor model that includes object orientation and/or spatial transformation information corresponding to each of the subsets. A tensor MRI image can be reconstructed from the set of k-space MRI data points by using the k-space tensor model to account for object orientation and/or spatial transformation.

Abstract: Inhibitors of protein kinase C (PKC)?, PKC? and PKC? are provided which are selective for those PKC isotypes. Combinatorial libraries for identifying protein kinases are also provided, as are methods of identifying protein kinases using those libraries. Additionally, methods of treating a mammal having a deleterious condition, where the condition is dependent on a protein kinase for induction or severity, are provided. Methods of inhibiting protein kinases are also provided.

Abstract: A method and computer program are provided for handing off a mobile device in communication with a first wireless system having a first network address to one or more other wireless systems within communication range of the mobile device. The method and computer program include periodically monitoring by the mobile device of communications from the first wireless system and the other wireless systems, calculating a signal strength associated with each of the monitored communications, selecting one of the other wireless systems, and transferring communication to the selected wireless system upon detection of a predetermined threshold of the signal strength associated with the first wireless system.

Abstract: The present invention relates to novel uses of AIM3 acting as a tumor suppressor, and more particularly to methods for using an AIM3 protein or a nucleic acid encoding the protein to activate ATM or ATR and to treat ATM- or ATR-mediated diseases. The AIM3 protein according to the present invention interacts directly with ATM/ATR so as to activate ATM/ATR and proteins regulated by ATM/ATR. Also, the AIM3 protein upregulates tumor suppressor gene p53 and its target genes so as to not only inhibit the proliferation of cells but also to induce apoptosis.

Abstract: Visual-assisted guidance of an ultra-thin flexible endoscope to a predetermined region of interest within a lung during a bronchoscopy procedure. The region may be an opacity-identified by non-invasive imaging methods, such as high-resolution computed tomography (HRCT) or as a malignant lung mass that was diagnosed in a previous examination. An embedded position sensor on the flexible endoscope indicates the position of the distal tip of the probe in a Cartesian coordinate system during the procedure. A visual display is continually updated, showing the present position and orientation of the marker in a 3-D graphical airway model generated from image reconstruction. The visual display also includes windows depicting a virtual fly-through perspective and real-time video images acquired at the head of the endoscope, which can be stored as data, with an audio or textual account.

Abstract: Each of a plurality of flash memory cells is programmed to a respective one of L?2 threshold voltage states within a threshold voltage window. Values of parameters of threshold voltage functions are adjusted in accordance with comparisons of the threshold voltages of some or all of the cells to two or more of m?2 threshold voltage intervals within the threshold voltage window. Reference voltages for reading the cells are selected based on the values. Alternatively, the m threshold voltage intervals span the threshold voltage window, and respective threshold voltage states are assigned to the cells based on numbers of cells whose threshold voltages are in the intervals, without re-reading the cells.

Abstract: Polyvalent, primary isolate nucleic acid compositions for inducing an immune response against HIV is disclosed. The composition and methods described herein are for the use of a DNA composition that encodes one or more different HIV envelope glycoproteins. The DNA composition can encode an HIV Gag protein. The DNAs encoding one or more HIV proteins are a combination of different nucleic acids, such as DNA plasmids, generated from primary isolate DNA of different HIV major group genetic clades and/or different proteins. HIV protein compositions for inducing an immune response against HIV are disclosed. Methods fro using the protein compositions as boosts following administration of the DNA compositions are provided.

Abstract: The present invention discloses novel methods of using Phleum spp. seeds, especially Timothy grass (P. pratense L.) seeds, for making gluten-free food products and the food products produced using such methods.

Abstract: Organic light emitting materials and devices comprising phosphorescent metal complexes comprising ligands comprising aryl or heteroaryl groups substituted at both ortho positions are described. An organic light emitting device, comprising: an anode; a hole transport layer; an organic emissive layer comprising an emissive layer host and an emissive dopant; an electron impeding layer; an electron transport layer; and a cathode disposed, in that order, over a substrate.

Abstract: A fiber optic communication system including a fiber optic link, a transmitter system and a receiver system. The transmitter system includes a laser source producing a light beam, and a polarization controller receiving the light beam and providing an expected pattern of changing states of polarization to the light beam to output light signals into the fiber optic link to cause the expected pattern of changing states of polarization to be transmitted along the fiber optic link. The receiver system is provided with a polarization analyzer, and a light detector. The light detector receives the light signals transmitted by the transmitter, and forwards data indicative of the light signals to the polarization analyzer. The polarization analyzer analyzing the data with an inverse polarization reference frame and generates an alert based on deviations of the data from the expected pattern of changing states of polarization.

Abstract: The present invention relates to a tissue clamp, a tool for grasping the clamp and a method of using the clamp for surgical procedures. The clamp has a fixture or fixtures positioned on the proximal end of the arms of the clamp so that a tool can be used by the surgeon to securely grasp the clamp during placement thereof on the vasculature or other tissue of the patient. The fixture can have a plurality of channels so that the user can select the angular orientation of the tool relative to the damp.

Abstract: Fixed-dried blood cells carrying an active agent are described, along with methods of making the same, methods of using the same, and compositions containing the sane. The blood cells may be red blood cells or blood platelets.

Abstract: A time-resolved fluorescence device is described for the detection and diagnosis of various metabolic diseases in a noninvasive or minimally invasive manner. The device uses an ultra-short excitation pulse that comprises of a repetition of nanosecond pulses. The excitation pulse is directed incident onto a strategically selected area of the patient body such as the forearm, the feet, and the palm. This light interacts with the different layers of the skin. The absorbed light excites conditions of interest in the skin, which in turn generate a fluorescence signal, which is collected by a detector. A processor is coupled to the detector to measure the transient fluorescence intensity decay of the skin in terms of lifetimes, and the contribution of individual fluorophores to the overall fluorescence signal.

Abstract: The present invention relates to a method for preparing an organic light-emitting diode, including: (A) providing a substrate with a first electrode thereon; (B) using a first solution to form a first light-emitting layer over the first electrode, where the first solution includes a first solvent and a first dye; (C) using a second solution to form a second light-emitting layer over the first light-emitting layer, where the second solution includes a second solvent and a second dye, and the first solvent and the second solvent are different solvents and satisfy at least one of the following conditions: the dipole moment difference between the first solvent and the second solvent being 0.5 D or more, or the viscosity of the first solvent being 0.3 mPa·s or more; and (D) forming a second electrode over the second light-emitting layer.

Abstract: An electrically-induced deflective amplification sensor as an actively controlled and reconfigurable nanomechanical sensor for the detection and recognition of chemicals, biomolecules, and gaseous molecules. The electrically-induced deflective amplification sensors use electric fields to control the bending of transducers, have adjustable sensitivities that depend on electric field strength, and reconfigurable operation ranges for the detection of target molecules at ultra-low and ultra-high concentrations. The sensors are highly integrated, sensitive, provide real-time detection ability, and do not require labels. The electrically-induced deflective amplification transducers can be reconfigured to identify molecules in spectroscopy. A new type of electrophoresis is established using nanostructured transducers. The E-IDEA is applicable to optical fiber, nanomechanical cantilever, waveguide and nanowire or nanotube tranducers.

Abstract: A cache and TLB layout and design leverage repeater insertion to provide dynamic low-cost configurability trading off size and speed on a per application phase basis. A configuration management algorithm dynamically detects phase changes and reacts to an application's hit and miss intolerance in order to improve memory hierarchy performance while taking energy consumption into consideration.