Abstract: A pharmaceutical composition having a transcription factor decoy and a pharmaceutical acceptable carrier thereof is provided, wherein the transcription factor decoy is TCF decoy. A method for curing or preventing endotoxin-treated endothelial cells from apoptosis is provided. A method for treating or meliorating septic shock is also provided. The transcription factor decoy is effective on melioration of endothelial cell death after lipopolysaccharide challenge. Furthermore, the pharmaceutical composition is easy to be prepared, economic and has low immunogenicity.

Abstract: Disclosed herein are systems and methods for reducing effects of restless legs syndrome (RLS) in a subject. The method includes identifying, on the subject, a body region affected by RLS, placing an emitter unit in direct contact with skin of the body region, wherein the emitter unit includes at least one emitter that emits near-infrared light, and activating the emitter to emit an effective amount of near-infrared light for inducing release of nitric oxide from hemoglobin or generation in the endothelium. Also disclosed is an emitter unit that is placed in direct contact with a subject's skin associated with RLS to reduce the effects of RLS. The emitter unit emits an effective amount of near-infrared light directed to the subject's skin to induce release of nitric oxide from hemoglobin or generation in the endothelium, and a module configured to toggle the emitter unit between a transmitting and a nontransmitting mode.

Abstract: Compounds and methods for treating cancer or inducing apoptosis in proliferating cells. The compounds are shown in formula I: wherein X is selected from hydroxyl, thiol, and amino; Y is selected from carboxyl and sulfonyl; R1, R2, R3, and R4 are selected from hydrogen, lower alkyl, and combinations thereof; R5, R6, and R7 are selected from hydrogen, halo, nitro, amino, methoxy, and combinations thereof; and pharmaceutically acceptable salts thereof.

Abstract: Methods, compositions and kits for diagnosis and treatment of age related macular degeneration.

Abstract: A footwear system for monitoring weight, posture allocation, physical activity classification, and energy expenditure calculation includes an accelerometer configured to obtain acceleration data indicative of movement of a user's foot or leg. The footwear system may also include a pressure sensing device mounted in an insole and configured to obtain pressure data indicative of pressure applied by a user's foot to the insole, as well as a transmitter communicatively coupled to both the accelerometer and the pressure sensing device and configured to transmit the acceleration and pressure data to a first processing device configured process the acceleration data and the pressure data to distinguish a first posture from a second posture different from the first posture and process the acceleration data and the pressure data to distinguish a first movement-based activity from a second movement-based activity different from the first movement-based activity.

Abstract: Provided are a communication method and system for sensor network. In reporting event occurrence in a real-time sensor network application, a cycle time is divided into an event announcement period and a data transmission period to provide real-time transmission performance and energy efficiency. Each of the periods is again divided into the number of slots equal to the maximum depth of a network. Respective nodes sequentially operate according to their depths in a routing tree during the event announcement period to receive the signal transmitted from the lower node. To remove sleep delay, a slot next to the signal reception slot becomes a signal transmission slot. A node sensed an event transmits a signal informing event occurrence during its signal transmission slot, and this signal includes only the address of the transmission node. When a signal does not exist in the event announcement period, no traffic occurs in the data transmission period and the upper nodes maintain a sleep state.

Abstract: A structure of a solar cell is provided. The structure of the solar cell includes a substrate, a base and a plurality of nanostructures. The base is disposed on the substrate. The nanostructures are disposed on a surface of the base, or a surface of the base includes the nanostructures, so as to increase light absorption of the structure.

Abstract: The subject invention provides silica-based material that has high affinity to chitin, chitin derivatives and chitin-containing microorganisms at an acidic pH. In an embodiment, the silica-based material surface comprises glass. Also provided are methods for preparing the subject silica-based chitin-binding material. In addition, the subject invention provides rapid, specific, sensitive, accurate and convenient methods for detection, isolation and purification of chitin, chitin derivatives and chitin-containing microorganisms.

Abstract: The invention provides anti-14-3-3 eta antibodies that specifically bind to the human 14-3-3 eta protein isoform in its natural configuration while exhibiting selectivity over human 14-3-3 alpha, beta, delta, epsilon, gamma, tau, and zeta protein isoforms. Methods, kits and pharmaceutical compositions comprising said specific anti-14-3-3 eta antibodies are further provided for the diagnosis and treatment of arthritis.

Abstract: Blockade of mismatch repair in a plant can lead to hypermutation and a new genotype and/or phenotype. One approach used to generate hypermutable plants is through the expression of dominant negative alleles of mismatch repair genes in transgenic plants or derived cells. By introducing these genes into cells and transgenic plants, new cell lines and plant varieties with novel and useful properties can be prepared more efficiently than by relying on the natural rate of mutation. Moreover, methods to inhibit the expression and activity of endogenous plant MMR genes and their encoded products are also useful to generate hypermutable plants.

Abstract: The present invention provides a ceramic material allowing a pellet having higher density and satisfactory Li ion conduction to be obtained. The ceramic material contains Li, La, Zr, Al and O and has a garnet-type or garnet-like crystal structure, the ratio of the number of moles of Li with respect to La being 2.0 or greater to 2.5 or lower.

Abstract: A method for increasing production of ethanol in an ethanologenic cell using an autoinducer molecule, for example AI-2.

Abstract: A thermoacoustic device includes at least one first electrode, at least one second electrode, a thermoacoustic element, a base and a plurality of fins. The at least one second electrode is spaced from the at least one first electrode. The thermoacoustic element is electrically connected with the at least one first electrode and the at least one second electrode. The base supports the thermoacoustic element and the at least one first electrode and the at least one second electrode. The fins are in thermal engagement with the base.

Abstract: A modified graphite oxide material contains a thermally exfoliated graphite oxide with a surface area of from about 300 m2/g to 2600 m2/g, wherein the thermally exfoliated graphite oxide displays no signature of the original graphite and/or graphite oxide, as determined by X-ray diffraction.

Abstract: A carbon-based foam composite including a carbon-based foam and a solid state hydrogen storage material, methods for making the carbon-based foam composite, and methods for using the carbon-based foam composite. Representative carbon-based foams include cryogels, aerogels, and xerogels. Representative solid state hydrogen storage materials include metal hydrides and chemical hydrides.

Abstract: The present invention relates to regulation of cold sensation and pain. More particularly, the present invention is directed to nucleic acids encoding a member of the transient regulatory protein family, CMR1, which is involved in modulation of the perception of cold sensations and pain. The invention further relates to methods for identifying and using agents that modulate cold responses and pain responses stimulated by cold via modulation of CMR1 and CMR1-related signal transduction.

Abstract: A routing method for a network is provided. The routing method includes the steps of a) selecting one of a plurality of basic nodes as a cluster head; b) broadcasting a first message by the cluster head; c) continuing to broadcast the first message by any of the plurality of basic nodes which receives the first message, until all the plurality of basic nodes receive the first message; and d) selecting a corresponding father node by each of the plurality of basic nodes based on an information associated with the first message.

Abstract: Coatings comprising functionalized graphene sheets and at least one binder. In one embodiment, the coatings are electrically conductive.

Abstract: Presentation of images showing with high resolution the state of a surgical field during surgery is realized with a simple configuration. When performing surgery, a three-dimensional model is generate based on MRI images of a patient captured prior to surgery, and three-dimensional coordinates of each location on a surface of the patient are measured by scanning a laser beam over the surface and detecting laser beam reflected therefrom, and correspondence is made with the MRI image for each location of the surface (frameless/markerless: steps 100 to 116), the position of a surgical instrument is also detected by the laser beam, the position of the surgical instrument derived, and images of the surgical instrument combined onto the MRI images and displayed during surgery (steps 120 to 130).

Abstract: The present invention provides a method for diagnosing cancer, predicting a disease outcome or response to therapy in a patient sample. The method involves isolating a circulating tumor cell (CTC), for example, a viable CTC, from a sample using a parylene microfilter device comprising a membrane filter having or consisting of a parylene substrate, which has an array of holes with a predetermined shape and size; and detecting and quantifying telomerase activity in blood circulating tumor cells. The invention further provides methods of using cells live-captured in various applications.