Abstract: Improved systems and methods are provided herein for passively filtering out droplets of different size such as satellite droplets from the generation of primary droplets and use these satellite droplets as the source for monodispersed production of submicron emulsions. The systems and methods described use active flow control to sort droplets of different size into desired collecting zones and use conventional shearing principles, and, as a result, provide 100% filtration of satellite droplets regardless of size differences.

Abstract: An apparatus comprises a radio frequency magnetic field unit to generate a desired magnetic field. In one embodiment, the radio frequency magnetic field unit includes a first aperture that is substantially unobstructed and a second aperture contiguous to the first aperture. In an alternative embodiment, the radio frequency magnetic field unit includes a first side aperture, a second side aperture and one or more end apertures. In one embodiment of a method, a current element is removed from a radio frequency magnetic field unit to form a magnetic field unit having an aperture. In an alternative embodiment, two current elements located opposite from one another in a radio frequency magnetic field unit are removed to form a magnetic filed unit having a first side aperture and a second side aperture.

Abstract: An embodiment of the invention provides a method including detecting a select hazardous condition by at least one triggering alarm unit of a plurality of interconnected hazardous condition alarm units. An actuatable latch in the triggering alarm unit is switched from an unlatched state to a latched state. An audible alert is generated in all of the interconnected alarm units. A test switch is actuated to identify the triggering alarm unit. Actuating the test switch disables the audible alert in each alarm unit having an actuatable latch in the unlatched state. A reset switch is actuated in only one of the alarm units to reset the actuatable latch in each of the alarm units to the unlatched state.

Abstract: Polypeptide and polynucleotide vaccines effective to treat or prevent infection of a mammal, such as a dog, a cat, or a human, by a protozoan. Methods of treatment and prevention are also provided, including therapeutic administration of the vaccine to an infected mammal to prevent progression of infection to a chronic debilitating disease state. Preferred embodiments of the polynucleotide vaccine contain nucleotide coding regions that encode polypeptides that are surface-associated or secreted by T. cruzi. Optionally the efficacy of the polynucleotide vaccine is increased by inclusion of a nucleotide coding region encoding a cytokine. Preferred embodiments of the polypeptide vaccine include immunogenic peptides that contain membrane transducing sequences that allow the polypeptides to translocate across a mammalian cell membrane.

Abstract: Stable and active arabinitol dehydrogenases (LAD) from Neurospora crassa and mutants thereof are disclosed. Arabinitol dehydrogenases are useful in the production of xylitol and ethanol from an arabinose containing substrate. Recombinant and heterologously expressed arabinitol dehydrogenases are useful in converting biomass into biofuels and other industrial food products.

Abstract: Bacteria are manipulated to create desirable output traits using dominant negative alleles of mismatch repair proteins. Enhanced hypermutation is achieved by combination of mismatch repair deficiency and exogenously applied mutagens. Stable bacteria containing desirable output traits are obtained by restoring mismatch repair activity to the bacteria.

Abstract: This invention provides compounds represented by the structure of the general formula (A): wherein L is a lipid or a phospholipid, Z is either nothing, ethanolamine, serine, inositol, choline, or glycerol, Y is either nothing or a spacer group ranging in length from 2 to 30 atoms, X is a physiologically acceptable monomer, dimer, oligomer, or polymer, wherein X is a glycosaminoglycan; and n is a number from 1 to 1000, wherein any bond between L, Z, Y and X is either an amide or an esteric bond.

Abstract: A method is disclosed to automatically segment 3D and higher-dimensional images into two subsets without user intervention, with no topological restriction on the solution, and in such a way that the solution is an optimal in a precisely defined optimization criterion, including an exactly defined degree of smoothness. A minimum-cut algorithm is used on a graph devised so that the optimization criterion translates into the minimization of the graph cut. The minimum cut thus found is interpreted as the segmentation with desired property.

Abstract: The present invention relates to methods and apparatuses for cell separation. In particular, the invention relates to separation of a particular cell type from a mixture of different cell types based on the differential rolling property of the particular cell type on a substrate coated with molecules that exhibits adhesive property with the particular cell type. This technology is adaptable for use in implantable shunts and devices for cell trafficking or tumor neutralization.

Abstract: A method for extracting edge with subpixel accuracy in photogrammetry, comprising steps of: a. capturing into a computer a picture, of which the edge is to be extracted; b. defining as a cell four neighboring pixels that form a square; c. recognizing the type of each cell composed of the four pixels; d. finding out side or sides of the cell that intersect with, the edge and figuring out the subpixel accuracy coordinates of the intersection points by linear interpolation; and e. connecting the intersection points to extract the edge. By this method edge curve is extracted rapidly and accurately. The edge determined in this way can be subpixel accurate.

Abstract: An antireflective coating is disclosed having at least one layer of a first material with a first index of refraction and a first thickness, the first index of refraction and first thickness substantially conforming to a refractive index profile matching a reflectionless potential.

Abstract: A method and system of ascertaining diagnostic information concerning a pathological specimen over a network is disclosed. The method comprises transmitting a digitized image of a pathological specimen to central location, and then receiving diagnostic information from the central location concerning the pathological specimen after an analysis of the digitized image has been performed at the central location.

Abstract: A method for using high intensity focused ultrasound (HIFU) to treat neurological structures to achieve a desired therapeutic effect. Depending on the dosage of HIFU applied, it can have a reversible or irreversible effect on neural structures. For example, a relatively high dose of HIFU can be used to permanently block nerve function, to provide a non-invasive alternative to severing a nerve to treat severe spasticity. Relatively lower doses of HIFU can be used to reversibly block nerve function, to alleviate pain, to achieve an anesthetic effect, or to achieve a cosmetic effect. Where sensory nerves are not necessary for voluntary function, but are involved in pain associated with tumors or bone cancer, HIFU can be used to non-invasively destroy such sensory nerves to alleviate pain without drugs. Preferably, ultrasound imaging synchronized to the HIFU therapy is used to provide real-time ultrasound image guided HIFU therapy of neural structures.

Abstract: A system for executing a cyber investigation by a non-expert user, including a computer having a processor, a memory, and a display; a computer-readable medium having stored thereon instructions for execution of a wizard application, the processor adapted to execute the instructions when the computer-readable medium is inserted into the computer, the processor programmed to: receive case information; receive a type of activity being investigated in response to user inputs to select the activity type from a list of possible activity types; guide the user through capturing data related to the selected activity type through steps presented to the user through one or more screens shown in the display, the steps presented such that a non-expert user can follow them; receive user inputs through a screens to obtain information needed to continue capturing the data related to the selected activity; and store the captured data in a removable data storage device or medium for analysis and use in the cyber investigation

Abstract: A communication method in a wireless communication system includes receiving information to determine whether or not to permit a relay of a communication between a first wireless station and a second wireless station, and relaying the communication based on at least the received information.

Abstract: A method of measuring the susceptibility of a subject to calcifying nanoparticle formation is disclosed. The method can include obtaining a cell culture comprising peripheral blood mononuclear cells, immune cells, or both, from a peripheral blood mononuclear fraction of a subject in a complete culture media; extracting a first aliquot and a second aliquot from the cell culture; and dispensing the first and second aliquot in different wells. The surface of the well containing the first aliquot can include a calcifying nanoparticle biofilm, while the well containing the second aliquot does not. The first and second aliquots can be incubated and the concentration of osteopontin in each aliquot determined. An osteopontin factor can be calculated and compared to osteopontin factors from a representative sample of other subjects. The osteopontin factor can be defined as the osteopontin concentration in the first aliquot divided by the osteopontin concentration in the second aliquot.

Abstract: The present invention relates to the formation and processing of nanostructures including nanotubes. Some embodiments provide processes for nanostructure growth using relatively mild conditions (e.g., low temperatures). In some cases, methods of the invention may improve the efficiency (e.g., catalyst efficiency) of nanostructure formation and may reduce the production of undesired byproducts during nanostructure formation, including volatile organic compounds and/or polycylic aromatic hydrocarbons. Such methods can both reduce the costs associated with nanostructure formation, as well as reduce the harmful effects of nanostructure fabrication on environmental and public health and safety.

Abstract: Fuel cell systems comprising ammonia borane or derivatives thereof as fuel and an anode and/or cathode which comprises a non-noble metal (e.g., copper) or a non-metallic substance (e.g., an iron electron-transfer mediating complex) as a catalyst are disclosed. Fuel cell systems comprising ammonia borane or derivatives thereof as fuel and a peroxide as an oxidant are also disclosed. Uses of the fuel devices are further disclosed.

Abstract: Compositions, kits and methods for inhibiting cancer cell (e.g., breast cancer cell) growth and treating a subject with cancer (e.g., breast cancer) include a therapeutically effective amount of an LBH inhibitor for inhibiting cancer cell growth and a pharmaceutically acceptable carrier, and/or a therapeutically effective amount of Wnt7a protein or nucleic acids encoding Wnt7a protein for inhibiting cancer cell growth and a pharmaceutically acceptable carrier. Methods of treating a subject having cancer (e.g., estrogen receptor negative basal-type breast cancer) include administering to the subject a composition including a pharmaceutical carrier and at least one of: an LBH inhibitor, a WNT7a protein, and a nucleic acid encoding WNT7a protein in an amount effective for inhibiting growth of cancer cells in the subject. Methods of detecting the presence of cancer (e.g.

Abstract: A spiral wound membrane module for forward osmotic use is disclosed. The membrane module may generally include a forward osmosis membrane in a spiral wound configuration. The module may include two inlets and two outlets, and may define first and second fluid flow paths. The inlets to each of the fluid flow paths may be generally isolated so as to prevent mixing. In some embodiments, the membrane module may include a distributer region and a collector region.