Patents Assigned to University
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Publication number: 20090258339Abstract: The present invention comprises, without limitation, systems, methods, and compositions for the detection, identification, and quantification, down to the single copy level, of human papillomavirus (HPV) in biological samples, including but not limited to, mammalian body fluids and cervix scrapings, for purposes of detection, treatment and/or management of cancer and dysplasia.Type: ApplicationFiled: September 16, 2008Publication date: October 15, 2009Applicant: The Regents of the University of MichiganInventors: David M. Kurnit, Kristine Kurnit
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Publication number: 20090258825Abstract: The present invention relates to compositions and methods for enhancing plant defenses against pathogens. More particularly, the invention relates to enhancing plant immunity against bacterial pathogens, wherein HopM11-300 mediated protection is enhanced, such as increased protection to Pseudomonas syringae pv. tomato DC3000 HopM1 and/or there is an increase in activity of an ATMIN associated plant protection protein, such as ATMIN7. Reagents of the present invention further provide a means of studying cellular trafficking while formulations of the present inventions provide increased pathogen resistance in plants.Type: ApplicationFiled: February 21, 2008Publication date: October 15, 2009Applicant: Michigan State UniversityInventors: Sheng Yang He, Kinya Nomura
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Publication number: 20090258064Abstract: Systems and methods for treating inflammatory and proliferative diseases, and wounds, using as a pharmacon a UCP and/or Fas antibody or other inhibitor, or combination thereof, and a therapeutically acceptable amount of a fatty acid metabolism inhibitor and/or a therapeutically acceptable amount of a glucose metabolism inhibitor, optionally in combination with one or more chemotherpeutic agents. In preferred embodiments, the invention combines an antibody against UCP and/or Fas antigen with an oxirane carboxylic acid, represented by etomoxir, and/or with a 2-deoxyglucose compound, represented by 2-deoxy-D-glucose. The systems and methods of the invention can be used to treat drug-resistant or multi-drug resistant cancers.Type: ApplicationFiled: February 23, 2009Publication date: October 15, 2009Applicant: The Regents of the University of ColoradoInventors: M. Karen Newell, Evan Newell, Elizabeth Villalobos-Menuey
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Publication number: 20090258078Abstract: The present invention is a method for encapsulating active protein in a polymeric nanocarrier. The instant method employs homogenization at subzero temperatures so that enzyme activity is retained. Enzymes which can be encapsulated by the present method include, for example, antioxidant enzymes and xenobiotic detoxifying enzymes. Encapsulation of an enzyme protects it from protease degradation and increases therapeutic half-life. Advantageously, polymeric nanoparticles of the invention are permeable to enzyme substrates and therefore enzymes encapsulated by the instant method can exert their effect without release from the nanocarrier. Methods for decomposing a reactive oxygen species, protecting against vascular oxidative stress, and detoxifying a xenobiotic are also provided.Type: ApplicationFiled: June 10, 2009Publication date: October 15, 2009Applicant: The Trustees of the University of PennsylvaniaInventors: Vladimir R. Muzykantov, Thomas D. Dziubla
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Publication number: 20090255869Abstract: The present invention relates to a combined anaerobic process apparatus for treating organic wastes, comprising: a first solid-liquid separator to separate organic wastes into liquid wastes and solid wastes; an acid-forming tank to decompose the liquid wastes separated through the first solid-liquid separator using acid-forming microorganisms; a USAB reactor to decompose the liquid wastes discharged from the acid-forming tank using anaerobic microorganisms; a crushing tank to crush the solid wastes separated through the first solid-liquid separator finely; a mixing tank to mix solid wastes crushed through the crushing tank with microorganisms; and a dry-anaerobic tank to dry solid wastes mixed with microorganisms through the mixing tank, in an anaerobic manner.Type: ApplicationFiled: March 23, 2009Publication date: October 15, 2009Applicant: Hanbat National University Industry-Academic Cooperation FoundationInventor: Sae Eun Oh
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Publication number: 20090256463Abstract: An electron emission device includes a cathode electrode and a gate electrode, the gate electrode is separated and insulated from the cathode, the gate electrode is a CNT layer, and the CNT layer includes at least a carbon nanotube film and a plurality of carbon nanotube reinforcement structures. A display that includes the electron emission device is also disclosed.Type: ApplicationFiled: December 31, 2008Publication date: October 15, 2009Applicants: Tsinghua University, HON HAI Precision Industry CO., LTD.Inventors: Lin Xiao, Liang Liu, Kai-Li Jiang, Shou-Shan Fan
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Publication number: 20090257254Abstract: Several inversion circuits used to convert a DC input to an AC output comprise two series circuits, at least one clamp capacitor, and at least one transformer. Each of the series circuits is in parallel with the DC input. The first series circuit includes one switch network and at least one transformer primary. The second series circuit includes one voltage-clamp network and at least one transformer primary. At least one clamp capacitor couples the first and the second series circuits, and is attached to each series circuit at a node between the respective transformer primary winding. The voltage-clamp network may be implemented with two of the three sub-circuits connected in series: a diode, a resister-capacitor-diode, and a MOSFET-capacitor.Type: ApplicationFiled: April 15, 2008Publication date: October 15, 2009Applicant: National Taiwan University of Science and TechnologyInventor: Ching-Shan Leu
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Publication number: 20090258822Abstract: The invention relates to Factor H gene polymorphisms and haplotypes associated with an elevated or a reduced risk of AMD. The invention provides methods and reagents for diagnosis and treatment of AMD.Type: ApplicationFiled: June 8, 2009Publication date: October 15, 2009Applicant: University of Iowa Research FoundationInventor: Gregory S. Hageman
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Publication number: 20090258860Abstract: Methods and compositions are provided for treating vascular depression. The methods involve administering to a subject in need thereof a xanthine derivative in a therapeutically effective amount to treat vascular depression, particularly the xanthine derivatives pentoxifylline or propentofylline. The methods may further include administration of an additional therapeutic agent in combination with the xanthine derivative selected from the group consisting of a selective serotonin reuptake inhibitor (SSRI), a serotonin-norepinephrine reuptake inhibitor (SNRI), and a drug used in the treatment of cerebrovascular disease. Compositions of the invention include pharmaceutical compositions and kits for treating vascular depression in a subject in need thereof that include therapeutically effective amounts of a xanthine derivative and an additional therapeutic agent selected from the group consisting of an SSRI, an SNRI, and a drug used in the treatment of cerebrovascular disease.Type: ApplicationFiled: June 19, 2009Publication date: October 15, 2009Applicant: Duke UniversityInventor: Ranga Krishnan
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Publication number: 20090257907Abstract: SmCo-based alloy nanoparticles composed mainly of a SmCo-based alloy containing Sm and Co as constituent elements, wherein the content of metal elements other than Sm and Co is 0.05-20 wt % with respect to the SmCo-based alloy.Type: ApplicationFiled: March 4, 2009Publication date: October 15, 2009Applicants: TDK Corporation, Tokyo University of Science Educational Foundation Administrative OrganizationInventors: Mamoru Satoh, Naoki Toshima, Mutsuko Kinjo, Haruki Kinjo, Shiho Tokonami
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Publication number: 20090258416Abstract: It is an object of the present invention to provide a polyion complex used as a non-viral gene vector, which achieves sufficiently high gene expression efficiency to a target cell. The polyion complex of the present invention comprises a block copolymer formed by binding polyethylene glycol to polycation via a disulfide group and a nucleic acid.Type: ApplicationFiled: September 4, 2006Publication date: October 15, 2009Applicant: The University of TokyoInventors: Kazunori Kataoka, Yuichi Yamasaki, Seiji Takae
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Publication number: 20090259099Abstract: Image-based control systems and methods automate the adjustment of medical devices. An image based-control system for an endoscope can include, in addition to the endoscope, a processing system and an actuator. The processing system can receive an image from an image capture device of the endoscope. Based on coordinates of a lumen in the image, the processing system can instruct the actuator to reorient the capture device to direct the capture device toward the lumen. The actuator can be coupled to a manual controller of the endoscope, such that the actuator can reorient the capture device via the manual controller. An image-based control method can include receiving an image from the capture device of the endoscope; identifying coordinates of a lumen in the image; mapping such coordinates to a physical position of the lumen relative to the capture device; and instructing an actuator to adjust an orientation of the endoscope.Type: ApplicationFiled: April 10, 2009Publication date: October 15, 2009Applicants: Georgia Tech Research Corporation, Emory UniversityInventors: Debao Zhou, Gary McMurray, Wayne Daley, Lou Jeansonne, Harvey Lipkin
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Publication number: 20090258792Abstract: Disclosed are methods for probing the immunogenic sugar moieties of prostate cancer cells. The methods detect a number of glyco-epitopes that are highly and differentially expressed among prostate cancers of various Gleason grades. The glyco-epitopes exist on the surfaces of prostate cells. The methods also comprise the detection of autoantibodies in prostate cancer subjects. The antibodies bound to a glyco-motif of N-glycans that is normally “cryptic.” This target is highly expressed in prostate cancers. Lectins and antibodies that detect these glyco-epitopes that expressed in prostate cancer tissues include Euonymus europaeus lectin (EEL); Psophocarpus Tetragonolobus Lectin-I (PTL-I); Griffonia Simplicifolia Lectin-I-A4 (GSL-I-A4); Griffonia Simplicifolia Lectin-I-B4 (GSL-I-B4); Sambucus nigra I agglutinin (SNA-I; Phaseolus vulgaris-L (PHA-L; Galanthus nivalis agglutinin (GNA); Narcissus pseudonarcissus agglutinin (NPA); Artocarpus integrifolia agglutinin (Jacalin); and mAb TM10 (IgM).Type: ApplicationFiled: April 10, 2009Publication date: October 15, 2009Applicant: The Board of Trustees of the Leland Stanford Junior UniversityInventors: Denong Wang, Leonore A. Herzenberg, Donna M. Peehl, Leonard A. Herzenberg
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Publication number: 20090260057Abstract: In a vehicle-to-vehicle wireless communication system utilizing certificates to verify trustworthiness of received communications, a method for distributing a list of certificate revocations to vehicles in the communication system. At least one main station transmits a list of certificate revocations to at least one vehicle and the vehicle thereafter transmits the list of certificate revocations to other vehicles in the communication network. Each of the other vehicles in the communication network updates its list of certificate revocations in response to the receipt of the list of certificate revocations from another vehicle in the system. The other vehicles thereafter transmit their updated list of certificate revocations to other vehicles in the system.Type: ApplicationFiled: April 11, 2008Publication date: October 15, 2009Applicants: Toyota Motor Engineering & Manufacturing North America, Inc., The Board of Trustees, The University of Illinois at Urbana-ChampaignInventors: Kenneth P. Laberteaux, Yih-Chun Hu, Jason Haas
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Publication number: 20090255459Abstract: A method for making zinc oxide nano-structure, the method includes the following steps. Firstly, providing a growing device, the growing device comprising a heating apparatus and a reacting room. Secondly, providing a growing substrate and forming a metal layer thereon. Thirdly, depositing a catalyst layer on the metal layer. Fourthly, placing the growing substrate into the reacting room together with a quantity of zinc source material. Fifthly, introducing a oxygen-containing gas into the reacting room. Lastly, heating the reacting room to a temperature range of 500˜1100° C.Type: ApplicationFiled: September 29, 2008Publication date: October 15, 2009Applicants: Tsinghua University, HON HAI Precision Industry CO., LTD.Inventors: Kai-Li Jiang, Qun-Qing Li, Shou-Shan Fan
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Publication number: 20090258835Abstract: The invention provides novel compounds of the Formula (I) that stimulate rates of glucose oxidation in myocardial cells: wherein W, Cyc, p, Y, X, Z, R, R1, R2, R3, R4, I, m and n are as defined for Formula (I) herein. The invention also relates to pharmaceutical compositions comprising compounds capable of stimulation of glucose oxidation, methods for increasing glucose oxidation rates in myocardial cells, and methods of treatment of myocardial ischemia.Type: ApplicationFiled: March 12, 2009Publication date: October 15, 2009Applicant: The Governors of the University of Alberta TEC EdmontonInventors: Gary D. Lopaschuk, John C. Vederas, Jason R. Dyck
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Publication number: 20090258448Abstract: A method for making the thermal electron emitter includes following steps. Providing a carbon nanotube film including a plurality of carbon nanotubes. Treating the carbon nanotube film with a solution comprising of a solvent and compound or a precursor of a compound, wherein the compound and the compound that is the basis of the precursor of a compound has a work function that is lower than the carbon nanotubes. Twisting the treated carbon nanotube film to form a carbon nanotube twisted wire. Drying the carbon nanotube twisted wire. Activating the carbon nanotube twisted wire.Type: ApplicationFiled: March 12, 2009Publication date: October 15, 2009Applicants: Tsinghua University, HON HAI Precision Industry CO., LTD.Inventors: Lin Xiao, Liang Liu, Chang-Hong Liu, Shou-Shan Fan
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Publication number: 20090259841Abstract: In a vehicle-to-vehicle communication network utilizing PKI security methods to protect communications and in which the PKI encryption utilizes a Certificate Authority having both a private key and a publicly distributed key, a method for allocating multiple certificates for each vehicle which are assigned to each vehicle in the communication network. The method includes the step of assigning a unique secret key k to each vehicle in the communication network. The Certificate Authority then creates a plurality of public key and private key encryption pairs for each vehicle and each encryption pair is associated with an index i. A plurality of certificates are then created with one certificate for each value of the index. A revocation list comprising the secret keys is maintained by the Certificate Authority so that all encryption pairs assigned to a particular vehicle may be revoked by the secret key k corresponding to that vehicle.Type: ApplicationFiled: April 11, 2008Publication date: October 15, 2009Applicants: Toyota Motor Engineering & Manufacturing North America, Inc., The Board of Trustees, University of Illinois at Urbana-ChampaignInventors: Kenneth P. Laberteaux, Yih-Chun Hu, Jason Haas
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Publication number: 20090259018Abstract: The present invention relates to methods of producing a protein concentrate from a starch containing grain and uses thereof. In an exemplary embodiment, the protein concentrate produced is used to prepare an aquaculture feed.Type: ApplicationFiled: April 15, 2009Publication date: October 15, 2009Applicants: The United States of America, as represented by Secretary of Agriculture, Montana Microbial Products, Inc., The Regents of the University of IdahoInventors: Frederic T. Barrows, Clifford A. Bradley, Robert D. Kearns, Brian D. Wasicek, Ronald W. Hardy
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Publication number: 20090257987Abstract: Methods of generating cells which secrete dopamine are disclosed. One method comprises incubating mesenchymal stem cells in a culture medium comprising brain derived neurotrophic factor (BDNF), wherein the culture medium comprises no more than 0.1 ?M retinoic acid (RA). Another method comprises incubating mesenchymal stem cells in a culture medium comprising glial-derived neurotrophic factor GDNF, transforming growth factor ?3 (TGF?3) and retinoic acid (RA). Cells generated by the above-described methods are also disclosed as well as uses thereof.Type: ApplicationFiled: April 8, 2009Publication date: October 15, 2009Applicant: Ramot At Tel Aviv University Ltd.Inventors: Daniel Offen, Eldad Melamed, Ran Barzilay, Inna Kan