Abstract: A double-sided grating divider acts as a light switch where the upper and lower grating dividers are arranged to accommodate a relative lateral shift therebetween of about one-fourth of the period of the diffraction grating elements and where the critical refraction angles of the grating dividers are more than about 43.6°. Lateral shift may be achieved by various devices including MEMS and metal couplers having a known/calibrated thermal coefficient of expansion over a temperature range of interest.

Abstract: A nanocomposite including: a thermoelectric material nanoplatelet; and a metal nanoparticle disposed on the thermoelectric material nanoplatelet.

Abstract: Disclosed are a homography estimation apparatus and method. A down-sampling unit reduces the reference image and the target image to the same size to generate down-sampled images. A feature point extraction unit extracts feature points from the reference image and the target image down-sampled to the same size, respectively. An outlier removal unit matches the feature points extracted from the reference image with the feature points extracted from the target image, and detects and removes outliers, which are feature points that do not match, from the matched feature points. A homography estimation unit estimates a homography using feature points from which outliers are removed. A reference image correction unit corrects the reference image using the estimated homography.

Abstract: 4-(pentafluorosulfanyl)benzenediazonium tetrafluoroborate salt was synthesized and isolated. The pentafluorosulfanyl salt was examined in a wide assortment of reactions to form novel SF5-bearing alkenes, alkynes, and biaryl derivatives using Heck-Matsuda, Sonogashira, and Suzuki coupling protocols. Dediazoniation of the salt furnished the corresponding p-SF5—C6H4X, C6H4OS(O)(CF3)?NSO2CF3, and p-SF5—C6H4—NTf2 derivatives. The azide derivative p-SF5—C6H4N3 entered into click chemistry with phenylacetylenes to furnish the corresponding triazoles. Various SF5-bearing alkenes were synthesized by coupling reactions using a metal catalyst. Fluorodediazoniation selectively furnished the fluoro derivative p-SF5—C6H4F. Homolytic dediazoniation gave the unsymmetrical biaryls, thus demonstrating the broad utility of pentafluorosulfanyl diazonium salts as building blocks of SF5-aromatics that are in high demand in many branches of chemistry including biomedicine and materials chemistry.

Abstract: The present disclosure generally relates to injectable compositions. More particularly, the present disclosure relates to injectable, thermogelling hydrogels and associated methods. In one embodiment, the present disclosure provides for a composition comprising a poly(N-isopropylacrylamide)-based macromer and a polyamidoamine-based macromer.

Abstract: Disclosed is a medical device treated with a phenolic compound and a process for treating a device with the phenolic compound. For example, a collagen or elastin-based scaffold can be treated with pentagalloyl glucose (PGG). The treated scaffold can become resistant to glycoxidative stress associated with advanced glycation end products (AGEs) that are present in a hyperglycemic environments associated with diabetes mellitus. The treated scaffold can exhibit a reduced increase in stiffness as compared to an untreated scaffold. The treated scaffold can also exhibit reduced inflammation without negatively affecting the ability of the scaffold to remodel in vivo.

Abstract: The present disclosure provides for a plasma system including a plasma device coupled to a power source, an ionizable media source and a precursor source. During operation, the ionizable media source provides ionizable media and the precursor ionizable media source provides one or more chemical species, photons at specific wavelengths, as well as containing various reactive functional groups and/or components to treat the workpiece surface by working in concert for synergetic selective tissue effects. The chemical species and the ionizable gas are mixed either upstream or midstream from an ignition point of the plasma device and once mixed, are ignited therein under application of electrical energy from the power source. As a result, a plasma effluent and photon source is formed, which carries the ignited plasma feedstock and resulting mixture of reactive species to a workpiece surface to perform a predetermined reaction.

Abstract: A method for realizing a semiconductor waveguide and an ultra-low-loss dielectric waveguide disposed on the same substrate is disclosed. The method includes forming a partial dielectric waveguide structure on the substrate, wherein the dielectric waveguide is annealed to reduce hydrogen incorporation, and wherein the top cladding of the dielectric waveguide is only partially formed by a first dielectric layer. A second substrate comprising a semiconductor layer having a second dielectric layer disposed on its top surface is bonded to the first substrate such that the first and second dielectric layers collectively form the complete top cladding for the dielectric waveguide. The second substrate is then removed and the semiconductor layer is patterned to define the semiconductor waveguide core.

Abstract: Disclosed is an device having high light-emitting efficiency. A metal complex represented by the following formula (1). In the formula (1), n represents an integer of 1 to 3. LA and LB each independently represent the moiety of a group bonded to an iridium atom, except for coordinating atoms. When n is 3, a metal complex represented by the following formula (1-3): wherein Me represents a methyl group) is excluded.

Abstract: Methods are disclosed for assessing the condition of a cartilage in a joint and assessing cartilage loss, particularly in a human knee. The methods include converting an image such as an MRI to a three dimensional map of the cartilage. The cartilage map can be correlated to a movement pattern of the joint to assess the affect of movement on cartilage wear. Changes in the thickness of cartilage over time can be determined so that therapies can be provided. The amount of cartilage tissue that has been lost, for example as a result of arthritis, can be estimated.

Abstract: Composite materials for carbon dioxide (C02) capture that include: (1) a mesoporous carbon source; and (2) an in situ polymerized polymer that is associated with the mesoporous carbon source, where the in situ polymerized polymer is selected from the group consisting of thiol-based polymers, amine-based polymers, and combinations thereof. Methods of making the composite materials for C02 capture include: (1) associating a mesoporous carbon source with monomers, where the monomers are selected from the group consisting of thiol-based monomers, amine-based monomers, and combinations thereof; and (2) polymerizing the monomers in situ to form said composite materials. Further embodiments of the present invention pertain to methods of capturing C02 from an environment by associating the environment with one or more of the aforementioned composite materials.

Abstract: A system for microsurgery includes a first assembly and a second assembly, each including: (1) a planar remote center of motion (RCM) device configured to constrain motion of a surgical instrument attached to the planar RCM device such that an axis of the surgical instrument passes through the RCM while remaining in a planar region defined based on a rotational orientation of the planar RCM device; and (2) a rotational device attached to the planar RCM device and configured such that an axis of rotation of the rotational device passes through the remote center of motion. The rotational orientation of the planar RCM device is defined about the axis of rotation. The first assembly and the second assembly are configured to be positioned such that a distance between the remote centers of motion of the first assembly and the second assembly is no greater than two centimeters.

Abstract: The invention provides a cementitious composition comprising a cement component comprising (i) an accelerant, (ii) a calcium sulphate source and (iii) an ettringite forming cement; an aggregate; and optionally water; wherein the cement has a minimum unconfined compressive strength of 1500 psi when tested in accordance with ASTM C1140 and/or C1604 at 15 minutes after placement; methods for its use and concrete formed from it.

Abstract: Polymeric conjugates comprising a polymeric backbone having attached thereto a bone targeting moiety and a therapeutically active agent, wherein the bone targeting moiety is attached to one end of the polymeric backbone via a branching unit such that a molar ratio of the bone targeting moiety to the polymer is at least 2:1, are disclosed. Pharmaceutical compositions containing these conjugates and uses thereof in the treatment of bone related disorders are also disclosed.

Abstract: Improved neuromodulation control of neurological abnormalities associated with effector organs in vertebrate beings using direct current stimulation for modulating spinal cord excitability, having a peripheral-current supplying component for providing direct current peripheral nerve stimulation and a spinal-current supplying component providing direct current for spinal stimulation, and a controller managing such functions.

Abstract: Described herein are novel biological circuit chemotactic converter that utilize modular components, such as genetic toggle switches and single invertase memory modules (SIMMs), for detecting and converting external inputs, such as chemoattractants, into outputs that allow for autonomous chemotaxis in cellular systems. Flexibility in these biological circuit chemotactic converter is provided by combining individual modular components, i.e., SIMMs and genetic toggle switches, together. These biological converter switches can be combined in a variety of network topologies to create network systems that regulate chemotactic responses based on the combination and nature of input signals received.

Abstract: An optical fiber environmental detection system comprising an interferometer, a broadband light source and a detector is disclosed. The interferometer further comprises a thin core fiber, a first single mode fiber and a second single mode fiber; wherein the thin core fiber is coupled to the first and second single mode fiber via a first junction and a second junction respectively. When an emission light reaches the first junction, high-order cladding modes will be excited. The excited cladding modes will interfere with the core mode at the second junction. The interferences determine the intensity maximum or minimum of the received signal. When there is an ambient environmental change, a shift of the received signal would be induced. According to the shift, environmental change, for instance ambient temperature, could be determined.

Abstract: A method and device for real-time mechanical and dosimetric quality assurance measurements in radiation therapy provides a unified measurement of mechanical motion and radiation components of the machine. The device includes an imaging surface for receiving multiple energy sources. The imaging surface has an imaging plane positioned on a same plane as an isocenter of a medical accelerator. A camera measures and records data related to the multiple energy sources. A mirror system can be used to direct the multiple energy sources to the camera for further processing. However, in some instances the mirror system may not be necessary. The device can also include computer control in order to automate the movement of the device and/or automation of the QA protocol. The device can also be used in executing a method for assessing gantry and collimator rotation.

Abstract: Surgical adhesives that include a blend of two different thermoreversible gelling polymers and a crosslinking agent are described. The first thermoreversible gelling polymer is partially or fully acrylated and the second thermoreversible gelling polymer includes dual functionality including acrylate functionality and amine-reactive functionality. The adhesives can provide gelling and covalent crosslinking within the polymers of the adhesive as well as crosslinking with surrounding tissue.

Abstract: A double-stranded nucleic acid molecule including (a) a sense strand which includes a nucleotide sequence corresponding to a target sequence indicated by any one of SEQ ID Nos.: 1 to 21, and (b) an antisense strand which includes a nucleotide sequence complementary to that of the sense strand specified in (a), wherein the double-stranded nucleic acid molecule is for suppressing the expression of at least one of APP and EBAG9 genes.