Abstract: Disclosed is a novel recombinant Bacillus bacterial strain constructed by genetic engineering which has high productivity of aipha-amylase. The Bacillus strain comprises an alpha-amylase gene inserted in the Bacillus chromosome under transcriptional control of a phage promoter. An efficient process for the rapid production of large amounts of alpha-amylase is also disclosed.

Abstract: The present invention is an apparatus and a method for populating a geospatial road database. In accordance with one embodiment of the invention, a geospatial database management system is mounted on a host vehicle and manages geospatial data relating to a travel path for the host vehicle. The embodiment further comprises a geospatial database to store data elements indicative of objects and their location. The embodiment further comprises a database manager component to maintain the geospatial database and receive database queries from a driver assist subsystem. The embodiment further comprises a database developer component is configured to develop the data elements in the geospatial database and receive database inputs from a lane level digitizer subsystem configured to receive inputs from a plurality of sensors mounted on the host vehicle. Finally, the embodiment comprises the plurality of sensors may include a Digital Global Positioning System, a digital camera, and a scanning range sensor.

Abstract: A radio link management system for a home or office substantially (i) an ad hoc network of agents wirelessly communicating among themselves, while (iii) clients wirelessly communicate with proximate agents. Control of the network may be centralized as network controller integrated with an agent, or may be distributed upon the network of agents. Some agent or agents, which may include an agent that is also the network controller, typically serves as a gateway device which connects to a worldwide communications network external to the home or office, normally by fiber or by wire. Each agent is most commonly a small radio transceiver plus logic and power supply that mounts upon a wall and plugs directly into an AC power socket. Agents wirelessly communicate among themselves and with the controller—which may be centralized or distributed—in a bandwidth-efficient mode since prime power is not an issue.

Abstract: Polymeric microparticles have been developed which encapsulate therapeutic compounds such as drugs, cellular materials or components, and antigens, and can have targeting ligands directly bound to the microparticle surface. Preferred applications include use in tissue engineering matrices, wound dressings, hone repair or regeneration materials, and other applications where the microparticles are retained at the site of application or implantation. Another preferred application is in the use of microparticles to deliver anti-proliferative agents to the lining of blood vessels following angioplasty, transplantation or bypass surgery to prevent or decrease restenosis, and in cancer therapy. In still another application, the microparticles are used to treat or prevent macular degeneration when administered to the eye, where agents such as complement inhibitors are administered.

Abstract: A method and an apparatus for encoding and decoding a modulation code are provided. The method includes: adding an error detection bit(s) to source information; performing k-constraint coding by inserting an error pattern that can be detected using an error detection code into a data stream that violates a k-constraint for a run length limited (RLL) code in a data stream comprising the error detection bit(s) and the source information, and recording the data stream after being k-constraint coded onto a recording medium; and reading the data stream recorded onto the recording medium and determining whether an error is present in the data stream.

Abstract: Micromechanical structures having at least one lateral capacitive transducer gap filled with a dielectric and method of making same are provided. VHF and UHF MEMS-based vibrating micromechanical resonators filled with new solid dielectric capacitive transducer gaps to replace previously used air gaps have been demonstrated at 160 MHz, with Q's˜20,200 on par with those of air-gap resonators, and motional resistances (Rx's) more than 8× smaller at similar frequencies and bias conditions. This degree of motional resistance reduction comes about via not only the higher dielectric constant provided by a solid-filled electrode-to-resonator gap, but also by the ability to achieve smaller solid gaps than air gaps. These advantages with the right dielectric material may now allow capacitively-transduced resonators to match to the 50-377? impedances expected by off-chip components (e.g., antennas) in many wireless applications without the need for high voltages.

Abstract: A directional balloon is provided that can be used for a medical intervention of a body lumen. In one aspect, the directional balloon inflates in a distal to proximal direction and deflates in a proximal to distal direction. In another aspect, the directional balloon inflates in a proximal to distal direction and deflates in a distal to proximal direction. The directional balloon is capable of providing an occlusive seal to protect against embolization. A suction catheter with a control means is provided to provide suction in a controlled fashion in a body lumen. The suction catheter is used during periods of a medical intervention that risks distal embolization. When turned on, the suction catheter is capable of removing unwanted materials. The suction means could be operated by a control means.

Abstract: Diagnostic and therapeutic applications for certain types of cancer and precancerous conditions, including those deriving from hematologic cells, are described. Of particular interest are those cancers and precancerous conditions associated with increased signaling in the RAS-MAP kinase pathway. The diagnostic and therapeutic applications described herein are based on certain mutations in the protein tyrosine phosphatase gene PTPN11 and its expression product, PTPN11, promoting a gain-of-function in PTPN11 activity. Also described are nucleotide sequences, amino acid sequences, probes, and primers related to PTPN11 and PTPN11 variants, and cells expressing such variants.

Abstract: Therapeutic agents which target heat shock protein (hsp) 27 in vivo are used to provide treatment to individuals, particularly human individuals, suffering from prostate cancer and other cancers that overexpress hsp27. A therapeutic agent, for example an antisense oligonucleotide or RNAi nucleotide inhibitor with sequence specificity for hsp27 mRNA, for example human hsp27 mRNA, is administered to an individual suffering from prostate cancer or some other cancer expressing elevated levels of hsp 27 in a therapeutically effective amount. The therapeutic agent is suitably formulated into a pharmaceutical composition which includes a pharmaceutically acceptable carrier, and packaged in dosage unit form. A preferred dosage unit form is an injectable dosage unit form.

Abstract: Graphite nanoplatelets of expanded graphite and composites and products produced therefrom are described. The preferred method of expanding the graphite is by microwaves or other radiofrequency wave treatment of intercalated graphite. The expanded graphite is preferably then crushed to nanometer (substantially all 200 microns or less). The expanded graphite is used in polymer composites. The expanded graphite is particularly useful for batteries, anodes and fuel cells.

Abstract: The present invention provides monoclonal antibodies that react against high molecular weight melanoma-associated antigen. These antibodies may be used for diagnostic and/or therapeutic purposes.

Abstract: The present invention provides a monoclonal antibody having a pathogenic activity that can induce pemphigus lesion, a peptide specifically recognized by the monoclonal antibody and useful as a therapeutic drug for pemphigus autoimmune disease, etc. As anti-mouse Dsg3 antibody-producing cells are present in the splenocytes of pemphigus vulgaris mouse model constructed by using autoantigen knockout mouse, cell fusion was conducted with the splenocytes of said mouse model and mouse myeloma cells using polyethyleneglycol, hybridomas were constructed, and monoclonal antibodies against Dsg3 were constructed. Among them, a monoclonal antibody having a pathological activity that can induce pemphigus lesions was screened, the base sequence and amino acid sequence in its variable region (heavy chain, light chain) was determined, and the specific epitope part was identified.

Abstract: Derivative compounds of 11-nonyloxy-undec-8(Z)-eonic acid that mimic epoxide metabolites are provided. Also provided are compositions comprising a therapeutically effective amount of the derivative compounds. The present invention further provides methods for the use of such compositions for the treatment of renal or cardiovascular disease and/or related conditions.

Abstract: The disclosure relates to an APS based integrated sun sensor comprising: a diaphragm unit, a detection unit, a processing electronics unit and an interface unit. The diaphragm unit is operatively connected with the detection unit for forming a sunspots image. The detection unit is configured for outputting a gray value of each pixel. The processing electronics unit is operatively connected with the detector unit and the interface unit respectively, for evaluating an attitude angle on the basis of the gray value and coordinate of each pixel. The interface unit is operatively connected with a host computer, for transferring the attitude angle to the host computer. This disclosure has such merits as high accuracy, wide FOV (Field of View), low power consumption, low weight, small size and high update rate.

Abstract: The present invention discloses a cone material in endodontic treatment. The cone material comprises a thermoplastic polyurethane and a filler. The thermoplastic polyurethane is formed by a. isophorone diisocyanate (IPDI) or hexamethylene diisocyanate (HDI), b. poly(butyleneadipate) glycol (PBA) and c. chain extender, wherein the molar ratio of PBA and the diisocyanate is equal to or more than 0.8. By changing the molar composition of the components such as polyol and diisocyanate, physical and chemical property of the disclosed cone material in endodontic treatment can be adjusted.

Abstract: The present invention provides a plurality of chimeric single chain variable region (scFv) antibodies. The chimeric scFv antibodies individually comprise variable regions from both horse and non-horse antibodies. Methods of making and using the plurality are also provided.

Abstract: A linear motor and a camera module having the linear motor are provided. The linear motor includes: a piezoelectric substrate generating a vibration mode in a longitudinal direction on the basis of an applied voltage; first and second shafts coupled to both sides of the piezoelectric substrate with the piezoelectric substrate interposed therebetween; and a moving member coupled to at least one of the first and second shafts to be movable in the longitudinal direction of the first and second shafts and connected to a camera lens on one side. Accordingly, it is possible to remove a dead zone with a simple structure, to prevent an unnecessary increase in thickness, not to cause a stoppage at the time of moving a camera lens, to cause a small amount of tilt to enable a linear control, and to contribute to a decrease in thickness and a compactness of a mobile terminal.

Abstract: Disclosed are DNA encoding a polypeptide which can modulate the activity of a muscle-specific tyrosine kinase, and others. The DNA is selected from the following members (a) to (d): (a) DNA comprising a specific nucleotide sequence; (b) DNA comprising a nucleotide sequence capable of hybridizing with a specific nucleotide sequence under stringent conditions; (c) DNA comprising a nucleotide sequence encoding an amino acid sequence having the substitution, deletion and/or addition of one or several amino acid residues in a specific amino acid sequence; and (d) DNA comprising a nucleotide sequence having 90% or higher homology to a specific nucleotide sequence.

Abstract: A transponder includes a stimulus driver configured to discharge an electrical stimulus when a trigger signal is received. A first conducting electrode is coupled to the stimulus driver and conducts the electrical stimulus discharged by the stimulus driver. A second conducting electrode is coupled to the stimulus driver and conducts the electrical stimulus conducted by the first conducting electrode. A depolarization resistance connects the first conducting electrode to the second conducting electrode in response to the trigger signal.