Patents Assigned to University
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Publication number: 20140100261Abstract: A method for treating an individual suffering from a cancer comprising administering to the individual a chemotherapeutic agent, and ii) one antisense oligonucleotide having nucleotides in the sequence set forth in Seq. ID No. 4 and which antisense oligonucleotide has a phosphorothioate modification that increases the stability thereof in vivo, wherein the cancer expresses testosterone-repressed prostate message-2 (TRPM-2), thereby treating said individual.Type: ApplicationFiled: September 16, 2013Publication date: April 10, 2014Applicant: THE UNIVERSITY OF BRITISH COLUMBIAInventors: Martin Gleave, Paul S. Rennie, Hideaki Miyake, Colleen Nelson
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Publication number: 20140099054Abstract: An apparatus and corresponding method in which the apparatus includes a dielectric waveguide and a metallic waveguide. The dielectric waveguide has an effective mode index and a longitudinal dimension. The metallic waveguide has a longitudinal dimension and supports a surface plasmonic mode of propagation for a wavelength lambda. The metallic waveguide and the dielectric waveguide are adjacent to each other and overlap each other by a length along the longitudinal dimensions of both the dielectric waveguide and the metallic waveguide, wherein the length is greater than the wavelength lambda in the metallic waveguide. The metallic waveguide is coupled to the dielectric waveguide where the metallic waveguide and the dielectric waveguide overlap each other.Type: ApplicationFiled: December 11, 2013Publication date: April 10, 2014Applicant: Carnegie Mellon UniversityInventors: Eric J. Black, James A. Bain, Stephen P. Powell, Tuviah E. Schlesinger
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Publication number: 20140100265Abstract: Currently no therapies that provide either protection or restoration of neuronal function for adult onset neurodegenerative diseases such as Parkinson's disease exist. Many clinical efforts to provide such benefits by infusion of neurotropic factors have failed. An alternative approach such as viral construct transduction may be used to directly activate the intracellular signaling pathways that mediate neurotrophic effects and induce axon growth. Viral construct transduction of dopaminergic neurons with a constitutively active human form of the p70S6K gene—hp70S6K (CA)—was shown to induce axon regeneration from living dopaminergic cell bodies that had no living axons.Type: ApplicationFiled: September 17, 2013Publication date: April 10, 2014Applicant: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORKInventor: Robert E. Burke
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Publication number: 20140101440Abstract: A method for resolving disputes between users in network communications using digital arbitration. The method comprising the steps of agreeing on a contract between the users and choosing a set of arbitrators; appealing to the arbitrators by a first user, if he/she suspects the second user violates the agreement; and giving the information needed to reconstruct a resource of the second user, if a large enough number of arbitrators agree that the second user actually violated the agreement.Type: ApplicationFiled: October 10, 2012Publication date: April 10, 2014Applicant: Ben-Gurion University of the NegevInventors: Ofer Hermoni, Niv Gilboa, Shlomi Dolev
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Publication number: 20140100419Abstract: The present invention relates to methods for improving the ability of spermatozoa to fertilize an egg in vitro and/or vivo, said method comprising providing a medium comprising active vitamin D (calcitriol) or analogs thereof, providing a sample of spermatozoa, and incubating said sample of spermatozoa with said medium. In addition, the invention relates to compositions comprising active vitamin D or analogs thereof for use in the treatment of infertility in a male or female subject.Type: ApplicationFiled: January 31, 2012Publication date: April 10, 2014Applicant: RIGSHOSPITALET COPENHAGEN UNIVERSITY HOSPITALInventor: Martin Blomberg Jensen
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Publication number: 20140099695Abstract: An object of the present invention is to enable simpler operation in real time and culture while removing unnecessary cells from cultured cells for purification in analyzing, fractionating, and culturing the cells alive and to analyze and fractionate desired cells from the cultured cells to increase the purity, recovery rate, and viability of the cells. The present invention employs a cell-adhesive photocontrollable base material, wherein light irradiation causes the bond dissociation of a photolabile group comprising a coumarinylmethyl skeleton to produce the separation of a cell-adhesive material to leave a non-cell-adhesive material. As a result, cell images can be detected and analyzed to obtain the positional information of desired cells. Based on the positional information thus obtained, the cells can be analyzed and fractionated alive.Type: ApplicationFiled: April 11, 2012Publication date: April 10, 2014Applicants: HITACHI HIGH-TECHNOLOGIES CORPORATION, TOHO UNIVERSITYInventors: Toshiaki Furuta, Akinobu Suzuki, Hisashi Sugiyama, Satoshi Ozawa, Hiroko Tada
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Publication number: 20140100238Abstract: A method of diagnosing a subset of Epstein Barr Virus, Myalgic Encephalomyelitis Chronic Fatigue Syndrome (ME/CFS) patients through a multi-prong clinical/serological analysis is provided wherein Epstein Barr Virus Abortive Lytic Replication (EBV) is determined as the specific causal agent through the use of serum antibodies to EBV encoded dUTPase and serum antibodies to EBV DNA Polymerase as molecular markers. A method of treating patients diagnosed with Epstein Barr Virus Abortive Lytic Replication (EBV), Myalgic Encephalomyelitis Chronic Fatigue Syndrome (ME/CFS) with specific antiviral nucleosides is also provided, to alleviate the condition.Type: ApplicationFiled: October 4, 2012Publication date: April 10, 2014Applicants: OHIO STATE UNIVERSITY, CFS, LLCInventors: A. Martin Lerner, Ronald M. Glaser
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Publication number: 20140099345Abstract: The present invention relates to omega-3 diglyceride emulsions characterized in that the lipid phase comprises at least about 40 wt.-% of diglycerides. Preferably about 70 wt.-% of the acyl-groups of said diglycerides are eicoapentaenoic acid (EPA) groups and/or docasahexaenoic (DHA) groups. The invention further relates to methods of treatment using the omega-3 diglyceride emulsions.Type: ApplicationFiled: December 10, 2013Publication date: April 10, 2014Applicant: The Trustees of Columbia University in the City of New YorkInventors: Richard J. Deckelbaum, Yvon Carpentier
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Publication number: 20140100129Abstract: There is provided a method of therapy of atherosclerosis, by providing microRNA let-7g, an analogue thereof or modified let-7g to organisms to inhibit the expression of lectin-like oxidized low density lipoprotein receptor-1 (LOX-1), and the binding of LOX-1 and oxidized low-density lipoprotein (oxLDL), so as to block the pathogenesis of atherosclerosis. Also, a method of diagnosis of atherosclerosis comprises determining the levels of microRNA let-7g in serum or plasma samples of organisms, in which the levels of microRNA let-7g is estimated in individuals with atherosclerosis as compared to individuals without atherosclerosis.Type: ApplicationFiled: September 24, 2013Publication date: April 10, 2014Applicant: KAOHSIUNG MEDICAL UNIVERSITYInventors: Suh-Hang JUO, Ku-Chung CHEN, I-Chung HSIEH, Ching-Yu HU
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Publication number: 20140100183Abstract: The present invention concerns compositions, methods and/or apparatus of central administration of various CNS-active agents. In particular embodiments, intrathecal administration is advantageous for decreasing the systemic concentrations of CNS agent, thereby decreasing side effect toxicity, while allowing more effective delivery of the agent to the site of action, simultaneously decreasing the dosage delivered to the subject. In particular embodiments, ICV delivery may be of use for patients who have previously proven to be refractory to systemic administration of CNS agents, in some cases due to systemic side effects, or for those patients whose symptoms are of sufficient severity to warrant more aggressive therapeutic intervention. ICV administration allows not only lower systemic concentration but also higher therapeutically effective concentration within the CNS.Type: ApplicationFiled: April 12, 2013Publication date: April 10, 2014Applicant: The Regents of the University of Colorado, a body corporateInventors: Daniel J. ABRAMS, Raymond BUNCH, Tom ANCHORDOQUY, Karen E. STEVENS
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Publication number: 20140098776Abstract: The present disclosure provides channel sensing in an efficient manner in a cognitive radio MAC protocol and improves channel utilization. Proposed is an Adaptive Channel Sensing (ACS) for variably sensing a channel in accordance with a Fixed Channel Sensing (FCS) and a channel state so as to perform the channel sensing in an efficient manner while reducing the power consumption of a terminal Further proposed is a self-scheduling mechanism which enables multiple terminals to simultaneously transceive data by means of a slot-based contention on the basis of the results of the FCS and ACS, which are proposed by the present disclosure.Type: ApplicationFiled: May 31, 2012Publication date: April 10, 2014Applicants: RESEARCH & BUSINESS FOUNDATION SUNGKYUNKWAN UNIVERSITY, Samsung Electronics Co., Ltd.Inventors: Se-Youn Lim, Tae-Jin Lee
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Publication number: 20140098719Abstract: A method and an apparatus for performing hybrid automatic repeat request (HARQ) in a wireless communication system is provided. UEs that use the same application for D2D communications form a sharing group so that reliability of transmission of a physical uplink shared channel (PUSCH) and a physical uplink control channel (PUCCH) among terminals that perform the D2D communications is guaranteed. In addition, among the terminals that perform the D2D communications, uplink transmission points in time determined in accordance with TDD configuration are checked and determined (calculated) so that the PUSCH and the PUCCH are correctly transmitted and received.Type: ApplicationFiled: October 8, 2013Publication date: April 10, 2014Applicants: SUNGKYUNKWAN UNIVERSITY FOUNDATION FOR CORPORATE, LG ELECTRONICS INC.Inventors: Hak Seong KIM, Oh Soon SHIN, Shan Ai WU, Yo An SHIN, Mo Chan YANG, E Rang LIM
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Publication number: 20140097817Abstract: A monitoring method with a function of correlation-based system identification applicable for a digitally controlled DC-DC converter system is revealed. The monitoring method includes a plurality of steps. After the system is operated in a steady state, input a pseudo random binary sequence signal into the system via a pseudo random binary sequence generator and store the pseudo random binary sequence signal and an output signal of a path to be monitored in a memory unit. Then perform a correlation analysis of data stored in the memory unit by a correlation analysis module and output an impulse response. Next obtain a frequency response of the impulse response by a discrete-time Fourier transform module. Finally, smooth the frequency response by an adaptive sliding window smoothing module so that a is monitoring curve of the frequency response becomes smooth.Type: ApplicationFiled: January 9, 2013Publication date: April 10, 2014Applicant: NATIONAL CHENG KUNG UNIVERSITYInventors: CHUN-YEN LIU, CHIEN-HUNG TSAI, CHUN-HUNG YANG, SHYH-MING LIN
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Publication number: 20140098289Abstract: A content processing apparatus is provided. The content processing apparatus includes an input unit which receives high resolution content, a data processor which generates a video frame by processing the high resolution content, and a controller which, if an output resolution of a display panel, which is to display the video frame, is lower than the resolution of the high resolution content, controls the data processor to form an object corresponding to the high resolution content as an object for low resolution and add the object for low resolution to the video frame.Type: ApplicationFiled: April 23, 2013Publication date: April 10, 2014Applicants: Gangneung-wonju National University Industry Academy Cooperation Group, SAMSUNG ELECTRONICS CO., LTD.Inventors: Yong-seok JANG, Sung-wook PARK, Min-Seok KIM, Bong-gil BAK, Jae-jun LEE, Tae-yoon CHUNG
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Publication number: 20140097277Abstract: The invention relates to biodegradable iron alloy-containing compositions for use in preparing medical devices. In addition, biodegradable crystalline and amorphous compositions of the invention exhibit properties that make them suitable for use as medical devices for implantation into a body of a patient. The compositions include elemental iron and one or more elements selected from manganese, magnesium, zirconium, zinc and calcium. The compositions can be prepared using a high energy milling technique. The resulting compositions and the devices formed therefrom are useful in various surgical procedures, such as but not limited to orthopedic, craniofacial and cardiovascular.Type: ApplicationFiled: October 3, 2013Publication date: April 10, 2014Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATIONInventors: PRASHANT N. KUMTA, SUNG JAE CHUNG, PARTHA SAHA, OLEG VELIKOKHATNYI, MONI KANCHAN DATTA, DAE HO HONG, DA-TREN CHOU
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Publication number: 20140100049Abstract: An aspect of the invention relates to a golf swing analyzing apparatus, comprising: an arithmetic section operating to process the output of a first inertial sensor and the output of a second inertial sensor to calculate a relative angle between a forearm of a golfer and a golf club, the first inertial sensor being attached to a portion of the upper body of the golfer, the second inertial sensor being attached to the golf club.Type: ApplicationFiled: October 1, 2013Publication date: April 10, 2014Applicants: Keio University, Seiko Epson CorporationInventors: Ken OTA, Kazuhiro SHIBUYA
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Publication number: 20140097502Abstract: A semiconductor device has gate-all-around devices formed in respective regions on a substrate. The gate-all-around devices have nanowires at different levels. The threshold voltage of a gate-all-around device in first region is based on a thickness of an active layer in an adjacent second region. The active layer in the second region may be at substantially a same level as the nanowire in the first region. Thus, the nanowire in the first region may have a thickness based on the thickness of the active layer in the second region, or the thicknesses may be different. When more than one active layer is included, nanowires in different ones of the regions may be disposed at different heights and/or may have different thicknesses.Type: ApplicationFiled: October 8, 2013Publication date: April 10, 2014Applicants: Seoul National University R & DB Foundation, SAMSUNG ELECTRONICS CO., LTD.Inventors: Min-Chul SUN, Byung-Gook PARK
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Publication number: 20140100242Abstract: Methods are provided for identifying molecules that can be used to positively and negatively manipulate quorum-sensing-mediated communication to control bacterial behavior. Small-molecule antagonists that disrupt quorum-sensing-mediated activities are identified. Methods are provided for disrupting detection of acyl-homoserine lactone autoinducer in Gram-negative bacteria by contacting the bacteria with the antagonists. Methods of inhibiting quorum sensing-mediated activity in Gram-negative bacteria are provided wherein the activity is pathogenicity, bioluminescence, siderophore production, type III secretion, or metalloprotease production.Type: ApplicationFiled: September 17, 2013Publication date: April 10, 2014Applicant: THE TRUSTEES OF PRINCETON UNIVERSITYInventors: Bonnie Bassler, Lee Swem
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Publication number: 20140100396Abstract: The present invention provides, among other thing, methods for creating significantly deoxygenated bio-oils form biomass including the steps of providing a feedstock, associating the feedstock with an alkali formate to form a treated feedstock, dewatering the treated feedstock, heating the dewatered treated feedstock to form a vapor product, and condensing the vapor product to form a pyrolysis oil, wherein the pyrolysis oil contains less than 30% oxygen by weight.Type: ApplicationFiled: January 4, 2013Publication date: April 10, 2014Applicant: UNIVERSITY OF MAINE SYSTEM BOARD OF TRUSTEESInventors: William Joseph DeSisto, Marshall Clayton Wheeler, Adriaan R.P. van Heiningen
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Publication number: 20140099342Abstract: The embodiment described herein are related nanoemulsions comprising botulinum toxins. In one embodiment, the nanoemulsions are prepared by high pressure microfluidization and comprise a particle size distribution exclusively between 10 and 300 nm. The nanoemulsions contemplated by the present invention are useful for the cosmetic and medical treatment of muscular contracture states. For example, botulinum toxin may relax facial muscles such that skin wrinkles become smoother and less noticeable. Further, the present invention contemplates a cosmetic formulation that may be self-administered, for example, in the privacy of one's home and without medical supervision.Type: ApplicationFiled: October 9, 2012Publication date: April 10, 2014Applicant: UNIVERSITY OF MASSACHUSETTS LOWELLInventors: Jonathan Edelson, Robert Nicolosi
