Abstract: A method of preparing an ultra-nanoscale-LC monolithic separation medium for use in capillary columns, or channels in microfabricated devices (microchips), and capillaries prepared by the method are disclosed. The application of moderate positive pressure to both ends of the capillary during the monolith polymerization process permits the preparation of monolithic capillary columns having very low i.d., e.g., 25 ?m and smaller, with enhanced mass transfer properties and low back pressures, and excellent column-to-column reproducibility of retention times.

Abstract: Method of detecting molecules, using a sensor having a membrane layer having parallel pores extending through the membrane layer and incorporating therein probe molecules that bind with corresponding target molecules when present in the pores, electrodes, and an ionic solution in contact with the electrodes and the pores, wherein the electrodes are energized to induce an electrical current in the solution through the pores, wherein the electrical current induces an electrical parameter in the electrodes that is indicative of a through-pore electrical impedance of the pores, wherein the through-pore electrical impedance is increased when there is probe-to-target molecule binding in the pores relative to when there is an absence of such binding.

Abstract: A system and method for cancellation of RF interference in the optical domain. The system and method utilize two Mach-Zehnder electrooptic modulators biased for parallel counter-phase modulation. The method of signal subtraction is referred to as incoherent optical subtraction, since two independent laser sources serve as the optical carrier waves. The system has produced the broadband cancellation result while simultaneously recovering a 50 dBm signal which was initially “buried” under the broadband interference. The cancellation depths achieved by the system are due to the accurate channel tracking and precise time delays attainable with modern optical devices—unattainable with state-of-the-art electronic devices at the time of this writing.

Abstract: A hand held, portable drill bit sharpener is provided which may be powered by a standard commercially available electrical power tool. The power tool may be used to actuate the drill bit sharpener by arranging the drive shaft of the sharpener into the power tool chuck. This drive shaft is connected through a gear set to a biased rotating sharpening stone which is pressed against a drill bit tip. The drill bit may be held in the sharpener using a standard keyless drill bit chuck.

Abstract: A method for determining a quotient value from a dividend value and a divisor value in a digital processing circuit is provided. The method includes computing a reciprocal value of the divisor value and multiplying the reciprocal value by the dividend value to obtain a reciprocal product, the reciprocal product having an integer part. The method also includes computing an intermediate remainder value by computing a product of the integer part and the divisor value, and subtracting the resulting product from the dividend value and determining the quotient value based upon the intermediate remainder value.

Abstract: A magnetic coupling assembly has a supporting base, a first disk, a second disk and two piezoelectric actuators. The piezoelectric actuators are mounted between the supporting base and the first disk to drive the first disk to move along an axial direction of the supporting base and to adjust the air gap between the first and second disks. Each piezoelectric actuator has a housing, a pushing arm and at least one piezoelectric block. The pushing arm is mounted slidably in and extends out of the housing along a longitudinal direction parallel with the axial direction of the supporting base and has an end securely connected with the first disk. The at least one piezoelectric block is mounted in the housing and is attached to the pushing arm to push the pushing arm to move along the longitudinal direction.

Abstract: This invention provides RNA, oligoribonucleotide, and polyribonucleotide molecules comprising pseudouridine or a modified nucleoside, gene therapy vectors comprising same, methods of synthesizing same, and methods for gene replacement, gene therapy, gene transcription silencing, and the delivery of therapeutic proteins to tissue in vivo, comprising the molecules. The present invention also provides methods of reducing the immunogenicity of RNA, oligoribonucleotide, and polyribonucleotide molecules.

Abstract: A method of making a biobased-petrochemical hybrid polyol is provided. This method includes reacting a cyclic ether with a vegetable oil-based polyol in the presence of a cationic catalyst or a coordinative catalyst that includes a vegetable oil-based polyol ligand to form the biobased-petrochemical hybrid polyol. The biobased-petrochemical hybrid polyol that is created has a number average molecular weight of about 3,000 to about 6,000 and has a structure that is about 22% to about 36% biobased. In one aspect of the present invention, the cyclic ether is propylene oxide, and the propoxylated polyol formed from the propylene oxide and vegetable oil-based polyol is then reacted with ethylene oxide in the presence of a superacid catalyst to create a block copolymer with a terminal polyethylene oxide block having a high percentage of terminal primary hydroxyl groups.

Abstract: Methods of achieving high breakdown voltages in semiconductor devices by suppressing the surface flashover using high dielectric strength insulating encapsulation material are generally described. In one embodiment of the present invention, surface flashover in AlGaN/GaN heterostructure field-effect transistors (HFETs) is suppressed by using high dielectric strength insulating encapsulation material. Surface flashover in as-fabricated III-Nitride based HFETs limits the operating voltages at levels well below the breakdown voltages of GaN.

Abstract: A capacitive sensor system including a sensing plate, an amplifier, and a switching circuit is described. The sensing plate is capacitively coupled to a body surface. A change in the electric potential on the body surface generates an electric field that induces change in the electric potential of the sensing plate. The sensing plate includes a sensing node positioned in the electric field for generating an input signal from the electric field. The sensing plate is not in contact with the body surface. The amplifier receives the input signal at the input port, amplifies the input signal and generates an output signal at the output port. The switching circuit is connected to the input port and a reference voltage. The switching circuit non-continuously closes a shunting path from the sensing node to the reference voltage to reset the voltage at the sensing node.

Abstract: In an apparatus for providing a multimedia streaming service, a server transmits a Media Presentation Description (MPD) including information about media data to a client, receives a partial request message requesting a part of media data having a range according to a defined range in the MPD, and transmits to the client a segment having the range in response to the partial request message. The segment includes at least one fragment, segment index information indicating the position of the at least one fragment in the segment, and fragment index information indicating the position of each of a plurality of samples included in the at least one fragment.

Abstract: The present invention relates to a marker composition for pregnancy diagnosis in cattle, a pregnancy diagnosis composition, and a pregnancy diagnosis method, which use a pregnancy-specific protein in cattle. The present inventors discovered an ?1G subunit protein of the T-type calcium channel expressed specifically in pregnant cows, and produced a specific antibody against this protein. Therefore, the present invention has the effect of detecting pregnancy in cows easily, quickly, and accurately early in the pregnancy.

Abstract: A method for digital processing comprises receiving a first set of image data corresponding to a first time and a second set of image data corresponding to a different time. Intensity values for each of a first pixel and second pixel are extracted from each of the first and second set of image data. Substantially linear values in a plurality of intensity values are identified for each of the first and second pixels. For each of the first and second pixels, regression is performed on each of the substantially linear values in the plurality of intensity values. The regression may calculate an intensity level as a function of exposure time. The regression may generate slopes corresponding to the linear values for each of the first and second pixels. These slopes more accurately represent the actual ratio of intensity values. The ratios are useful in applications, such as, for example, polarization.

Abstract: Storage-stable, anti-microbial compositions and products include a carrier and a ceragenin compound suspended in the carrier. Ceragenin compounds suspended in the carrier include a sterol backbone and a number of cationic groups attached to the sterol backbone via hydrolysable linkages. The carrier has a pH of 5.5 or less, which acts to stabilize the hydrolysable linkages and increase the shelf-life of the anti-microbial compositions and anti-microbial products. Nevertheless, the ceragenin compounds described herein are designed to break down relatively quickly (e.g., within about 5 days) if the pH environment of the ceragenin compounds is raised to about pH 6.5 or greater.

Abstract: A latent fluorophore is derived from salicylic acid, and containing a fluorogenic group and a moiety represented by formula I wherein the fluorogenic group is directly linked to the moiety of formula I or indirectly linked thereto via a linkage structure. In addition, a method of preparing a latent fluorophore, a method of using the same and a kit containing the same are also introduced.

Abstract: Methods and computer program products for quantitative three-dimensional (“3D”) image correction in optical coherence tomography. Using the methods and computer program products, index interface (refracting) surfaces from the raw optical coherence tomography (“OCT”) dataset from an OCT system can be segmented. Normal vectors or partial derivatives of the curvature at a refracting surface can be calculated to obtain a refracted image voxel. A new position of each desired refracted image voxel can be iteratively computed. New refracted corrected voxel positions to an even sampling grid can be interpolated to provide corrected image data. In some embodiments, clinical outputs from the corrected image data can be computed.

Abstract: A synchronization method for impulse system ultra-wideband takes frame as basic unit for data transmission, each frame is divided into a preamble symbol part and a data part, wherein the preamble symbol part sends a known impulse sequence for channel estimation and synchronization; the data part takes the information to be transmitted; the preamble symbol part is divided into two parts of a positive and negative impulse sequence, which includes odd impulses with alternant positive and negative polarities, and a same direction impulse sequence, which is composed of impulses with same polarity and is the same as the polarity of the last impulse in the positive and negative impulse sequence. The method provides such advantages as high synchronization precision, small storage space, and capability of immediately finding out the synchronization position etc., and provides an important value for the development of the impulse system ultra-wideband wireless communication technique.

Abstract: A method of processing bundles of carbon nanotubes (CNTs). Bundles of CNTs are put into a solution and unbundled using sonication and one or more surfactants that break apart and disperse at least some of the bundles into the solution such that it contains individual semiconducting CNTs, individual metallic CNTs, and remaining CNT bundles. The individual CNTs are separated from each other using agarose bead column separation using sodium dodecyl sulfate as a surfactant. Remaining CNT bundles are then separated out by performing density-gradient ultracentrifugation.

Abstract: An Aphis glycines resistance Rag2 gene is provided herein, along with methods for identifying its presence using marker-assisted selection. A cultivar of G. max having resistance to Aphis glycines conferred by the Rag2 gene has been identified. The Rag2 gene, as well as the methods, aphid-resistant varieties, and markers disclosed herein may be used to breed new elite lines expressing soybean aphid resistance.

Abstract: The present invention provides compositions and methods for use in enzyme replacement therapy. The inventors disclose a method of producing membrane bound enzymes in an active soluble form by eliminating the glycosylphosphatidylinositol (GPI) membrane anchor. In particular the inventors disclose a soluble active form of the membrane bound enzyme TNSALP which they produced by deleting the GPI anchor single peptide sequence. They have further shown that this composition is useful for treatment of hypophosphatasia. The inventors also disclose oligo acid amino acid variants thereof which specifically target bone tissue.