Abstract: Compounds of formula (I): wherein R1 to R8, and X? are defined herein. Also disclosed are methods of making and using these compounds.

Abstract: A method to suppress thermal conductivities of nitride films by using stacking faults and/or nano-scale In-composition fluctuation(s). Therefore, the present invention reduces thermal conductivity of nitride while keeping electrical conductivity high. In addition, In composition fluctuations can enhance the Seebeck coefficient through thermionic emission. The present invention further discloses a nitride based (e.g. GaN) thermoelectric lateral device with a short length.

Abstract: A perpendicular magnetic recording medium according to which both the thermal stability of the magnetization is good and writing with a magnetic head is easy, and moreover the SNR is improved. In the case of a perpendicular magnetic recording medium comprising a nonmagnetic substrate (1), and at least a nonmagnetic underlayer (2), a magnetic recording layer (3), and a protective layer (4) formed in this order on the nonmagnetic substrate (1), the magnetic recording layer (3) comprises a low Ku region (31) layer having a perpendicular magnetic anisotropy constant (Ku value) of not more than 1×105 erg/cm3, and a high Ku region (32) layer having a Ku value of at least 1×106 erg/cm3. Moreover, the magnetic recording layer (3) is made to have therein nonmagnetic grain boundaries that contain a nonmagnetic oxide and magnetically isolate crystal grains, which are made of a ferromagnetic metal, from one another.

Abstract: A method of maintaining an information rate of a Brain-computer interface (BCI) system, implanted in a patient's brain, by regulating arousal level in the patient's brain is disclosed. The method includes selecting a patient with the implanted BCI device configured to receive neuronal activity from one or more electrodes connected to the patient's brain and to establish a communication channel between the patient and an external device controlled by the patient. Accordingly, a rate of information passage through the communication channel from the BCI device is measured, and a region of the patient's brain involved in arousal regulation, is stimulated in response to said measuring, under conditions effective to adjust the rate of information passing from the BCI device through the communication channel. A computer medium for carrying out this method and a BCI Arousal Regulation system are also disclosed.

Abstract: Methods and systems are described for determining, in a patient that suffers from a mood disorder (e.g., depression), a propensity of the patient to manifest reduced symptoms or levels of indicators of the mood disorder in response to a psychiatric treatment. This can involve determining levels of a marker (e.g., a metabolite) indicative of a brain bioenergetic state of the patient that is predictive of whether the patient will response favorably to an antidepression treatment. Such bioenergetic state markers, tending to normalize in response to antidepression therapy, can include, e.g., a pH, a magnesium level, and a phosphorus level. Brain levels of such markers can be determined by, e.g., 31P MRS.

Abstract: The present invention relates to a compound of formula (I). Provided is also a method of killing a cell that comprises administering the compound of formula (I). Provided is also a method of treating cancer or diabetes in a mammal that comprises administering the compound of formula I and respective pharmaceutical compositions thereof.

Abstract: The present invention provides a mimetic egg comprising lysozyme, a salt or biological fragment thereof or a lysozyme-related peptide and an active ingredient in its base material mimicking an egg of a vermin; and a vermin exterminating method using the mimetic egg.

Abstract: Two classes of hybrid/thermochemical water splitting processes for the production of hydrogen and oxygen have been proposed based on (1) metal sulfate-ammonia cycles (2) metal pyrosulfate-ammonia cycles. Methods and systems for a metal sulfate MSO4—NH3 cycle for producing H2 and O2 from a closed system including feeding an aqueous (NH3)4SO3 solution into a photoctalytic reactor to oxidize the aqueous (NH3)4SO3 into aqueous (NH3)2SO4 and reduce water to hydrogen, mixing the resulting aqueous (NH3)2SO4 with metal oxide (e.g.

Abstract: A method for acquiring MRI signals includes: applying one or more than one RF pulse, which carries at least two frequency components, and a slice/slab selection gradient to a subject, so that at least two slices/slabs of the subject respectively corresponding to the at least two frequency components are excited simultaneously; applying a plurality of spatial encoding gradients; applying a plurality of separation gradients for separating the at least two slices/slabs; and applying at least one coherent refocusing gradient between the plurality of separation gradients.

Abstract: The leading cause of graft failure is the subsequent development of intimal hyperplasia, which represents a response to injury that is thought to involve smooth muscle proliferation, migration, phenotypic modulation, and extracellular matrix (ECM) deposition. Surgical techniques typically employed for vein harvest—stretching the vein, placing the vein in low pH, solutions, and the use of toxic surgical skin markers—are shown here to cause injury. The invention therefore provides for non-toxic surgical markers than also protect against stretch-induced loss of functional viability, along with other additives. Devices and compositions for reducing physical stress or protecting from the effects flowing therefrom, also are provided.

Abstract: An air-guiding carrier type wind power collection device includes a floating body and two air guiding tubes. The floating body includes a compartment filled with an uprising gas having a density lower than that of air. The floating body includes a floating assembly controlling a pressure and a temperature of the uprising gas received in the compartment. The air guiding tubes extend through the compartment of the floating body. Each air guiding tube has an air inlet and an air outlet. The air outlet includes a peripheral wall having a windward section and a guiding section. The peripheral wall has a cutout portion formed between the windward section and the guiding section. An air channel is formed between and in communication with the air inlet and the air outlet of each air guiding tube. A wind power generating assembly is mounted in each of the air channels.

Abstract: The present disclosure relates to an example of a method for a first router to adaptively determine status within a network. The network may include the first router, a second router and a third router. The method for the first router may comprise determining status information regarding the second router located in the network, and transmitting the status information to the third router located in the network. The second router and the third router may be indirectly coupled to one another.

Abstract: The subject invention pertains to the treatment of tumors and cancerous tissues and the prevention of tumorigenesis and malignant transformation through the modulation of JAK/STAT3 intracellular signaling. The subject invention concerns pharmaceutical compositions containing cucurbitacin I, or a pharmaceutically acceptable salt or analog thereof. Another aspect of the invention concerns methods of inhibiting the growth of a tumor by administering a cucurbitacin I, or a pharmaceutically acceptable salt or analog thereof, to a patient, wherein the tumor is characterized by the constitutive activation of the JAK/STAT3 intracellular signaling pathway. The present invention further pertains to methods of moderating the JAK and/or STAT3 signaling pathways in vitro or in vivo using cucurbitacin I, or a pharmaceutically acceptable salt or analog thereof. Another aspect of the present invention concerns a method for screening candidate compounds for JAK and/or STAT3 inhibition and anti-tumor activity.

Abstract: Methods, media, and systems for detecting an anomalous sequence of function calls are provided. The methods can include compressing a sequence of function calls made by the execution of a program using a compression model; and determining the presence of an anomalous sequence of function calls in the sequence of function calls based on the extent to which the sequence of function calls is compressed. The methods can further include executing at least one known program; observing at least one sequence of function calls made by the execution of the at least one known program; assigning each type of function call in the at least one sequence of function calls made by the at least one known program a unique identifier; and creating at least part of the compression model by recording at least one sequence of unique identifiers.

Abstract: Described herein are compounds such as macromolecules that have been modified in order to facilitate crosslinking and methods of making and using thereof.

Abstract: Provided is a parallel operation processing apparatus and method. The parallel operation processing apparatus and method may generate an interpolated matrix with respect to a character included in each of a current frame and a next frame using a matrix corresponding to each of the current frame and the next frame generated, based on joint information corresponding to a plurality of joints included in the character. Also, the parallel operation processing apparatus and method may display an interpolated frame using the interpolated matrix.

Abstract: The disclosure relates to methods of treating tuberous sclerosis in a subject, comprising administering a composition comprising an mTOR inhibitor and a tyrosine kinase inhibitor to a subject that is diagnosed with, suspected of, or exhibiting symptoms of cancer. In some embodiments, the cancer is tuberous sclerosis. In some embodiments, the mTOR inhibitor is sirolimus and the tyrosine kinase inhibitor is imatinib. In some embodiments, the disclosure relates to a composition comprising an mTOR inhibitor and a tyrosine kinase inhibitor. In some embodiments, the disclosure relates to a composition comprising sirolimus and imatinib.

Abstract: The present invention relates to a method and a kit for detecting nucleic acid sequence variation using melting curve analysis, especially relates to a method and a kit for detecting nucleic acid sequence variation by melting curve analysis using self-quenched probe. Said method provides the characteristics of the self-quenched probe employed, as well as the corresponding nucleic acid amplification conditions, so that the probe can bind to the amplified target sequence, and variations of the target sequence can be detected by melting curve analysis. The present invention also encompasses a kit assembled according to the method described.

Abstract: A data-intensive computer includes a processing sub-system formed by a plurality of processing servers, a database sub-system formed by a plurality of database servers configured to form a collective database, and a unifying operating system environment. The unifying operating system environment extends across the processing sub-system and the database sub-system to coordinate operation of the plurality of processing servers and the plurality of database servers to act as components in a single data-intensive computer and presents the database sub-system to an application running in the data-intensive computer as a layer in a memory hierarchy of the data-intensive computer.

Abstract: A semiconductor surface light-emitting element of this invention is provided with a photonic crystal layer 6 obtained by periodically forming a plurality of holes H in a basic layer 6A comprised of a first compound semiconductor of the zinc blend structure and growing embedded regions 6B comprised of a second compound semiconductor of the zinc blend structure, in the holes H, and an active layer 4 to supply light to the photonic crystal layer 6, in which a principal surface of the basic layer 6A is a (001) plane and in which side faces of each hole H have at least three different {100} facets.