Patents Assigned to University
  • TRANSCRIPTION ACTIVATOR-LIKE EFFECTOR NUCLEASES (TALENS)
    Publication number: 20140087426
    Abstract: This application provides transcription activator-like effector nucleases (TALENs), polynucleotide sequences encoding the TALENs, expression cassettes for producing TALENs to target cleavage of nucleic acids, and methods of producing and using the TALENs.
    Type: Application
    Filed: September 24, 2013
    Publication date: March 27, 2014
    Applicant: The Chinese University of Hong Kong
    Inventors: Yun LIU, Christopher H.K. Cheng
  • Hepatocyte Growth Factor Mimics as Therapeutic Agents
    Publication number: 20140088004
    Abstract: Small molecule, peptidic hepatocyte growth factors mimics, which act as both mimetics and antagonists, have been generated. These molecules have been shown or predicted to have therapeutic potential for numerous pathologies including dementia, neurodegenerative disease, diabetes and metabolic syndrome, cancer, and defective wound healing.
    Type: Application
    Filed: April 2, 2012
    Publication date: March 27, 2014
    Applicant: WASHINGTON STATE UNIVERSITY
    Inventors: Joseph W. Harding, John W. Wright, Caroline C. Benoist, Leen H. Kawas, Gary A. Wayman
  • sGCalpha1 Inhibiting Compositions, and Methods of Treatment of Cancers Therewith
    Publication number: 20140088023
    Abstract: The present invention provides materials and methods useful to treat various sGC?1-expressing cancers. Materials include peptides which interfere with sGC?1's pro-survival functions, thereby resulting in apoptosis of sGC?1-expressing cells. In addition, the present invention provides screening assays, diagnostic assays, methods to prognose, methods to treat, and kits.
    Type: Application
    Filed: November 1, 2013
    Publication date: March 27, 2014
    Applicant: THE UNIVERSITY OF TOLEDO
    Inventors: Lirim Shemshedini, Shao-Yong Chen, Changmeng Cai, Chen-Lin Hsieh
  • 6,7-DIHYDRO-[1,3,4]THIADIAZOLO-[3,2-a][1,3]DIAZEPIN DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AS NEUROMUSCULAR BLOCKER OR SKELETAL MUSCLE RELAXANT, AND METHOD FOR THE PREPARATION
    Publication number: 20140088091
    Abstract: The present invention relates to a compound of formula 1, a pharmaceutical composition containing the compound, a method for its preparation as well as the use of the compound as neuromuscular blocker or skeletal muscle relaxant.
    Type: Application
    Filed: April 11, 2012
    Publication date: March 27, 2014
    Applicant: KING SAUD UNIVERSITY
    Inventors: Adel S. El-Azab, Hussein I. El-Subbagh, Khalid A. Al-Rashood, Kamal E. H. El-Taher, Mohamed A. Al-Omar, Ghada S. Hassan, Fatmah A. Al-Omary, Alaa A.-M. Abdelaziz, Mohamed M. Hefnawy
  • GENERATION OF HAPLOID PLANTS AND IMPROVED PLANT BREEDING
    Publication number: 20140090099
    Abstract: Methods and compositions for generating haploid organisms are described.
    Type: Application
    Filed: November 22, 2013
    Publication date: March 27, 2014
    Applicant: THE REGENTS OF THE UNIVERSITY OF CALIFORNIA
    Inventors: Simon Chan, Ravi Maruthachalam
  • OLEFIN-TRIGGERED ACID AMPLIFIERS
    Publication number: 20140087309
    Abstract: There are disclosed olefinic acid amplifier triggers and methods of using these compositions in, for example, photolithography.
    Type: Application
    Filed: March 28, 2012
    Publication date: March 27, 2014
    Applicant: THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK
    Inventors: Brian Cardineau, Robert L. Brainard
  • CATHODE COMPOSITE MATERIAL AND LITHIUM ION BATTERY USING THE SAME
    Publication number: 20140087266
    Abstract: A cathode composite material includes a cathode active material and a coating layer coated on a surface of the cathode active material. The cathode active material includes a lithium cobalt oxide. The coating layer includes a lithium metal oxide having a crystal structure belonging to C2/c space group of the monoclinic crystal system. The present disclosure also relates to a lithium ion battery including the cathode composite material.
    Type: Application
    Filed: November 30, 2012
    Publication date: March 27, 2014
    Applicants: HON HAI PRECISION INDUSTRY CO., LTD., TSINGHUA UNIVERSITY
    Inventors: YA-DONG LI, JUN LU, WEI-YANG WANG, DING-SHENG WANG, QING PENG
  • ENDOPARASITE CONTROL AGENT
    Publication number: 20140088157
    Abstract: Provided are an endoparasite control agent comprising a carboxamide derivative represented by the general formula (I): or a salt thereof as an active ingredient, and a method for controlling endoparasites, comprising orally or parenterally administering the endoparasite control agent.
    Type: Application
    Filed: March 1, 2012
    Publication date: March 27, 2014
    Applicants: NIHON NOHYAKU CO., LTD., THE UNIVERSITY OF TOKYO
    Inventors: Kiyoshi Kita, Akiyuki Suwa
  • Method and System for Optimizing Accuracy-Specificity Trade-offs in Large Scale Visual Recognition
    Publication number: 20140086497
    Abstract: As visual recognition scales up to ever larger numbers of categories, maintaining high accuracy is increasingly difficult. Embodiment of the present invention include methods for optimizing accuracy-specificity trade-offs in large scale recognition where object categories form a semantic hierarchy consisting of many levels of abstraction.
    Type: Application
    Filed: March 15, 2013
    Publication date: March 27, 2014
    Applicant: The Board of Trustees for the Leland Stanford, Junior, University
    Inventor: The Board of Trustees for the Leland Stanford, Junior, University
  • THREE LAYER CASCADE ADAPTIVE NEURAL FUZZY INFERENCE SYSTEM (ANFIS) BASED INTELLIGENT CONTROLLER SCHEME AND DEVICE
    Publication number: 20140087749
    Abstract: Intelligent technique is an effective method to perform the network resource management. A three layer cascade adaptive neural fuzzy inference system (ANFIS) based intelligent controller is proposed for the mobile wireless network to optimize the maximum average throughput, minimum transmit power and interference for multimedia call services. The proposed intelligent controller is designed with a three layer cascade architecture, which mainly contains an ANFIS rate controller (ARC) in the first layer, an ANFIS power controller (APC) in the second layer and an ANFIS interference controller (AIC) in the third layer. The design aim of the proposed three layer cascade ANFIS cognitive engine is maximizing the average throughput of the mobile wireless network, while minimizing the transmit power and interference power.
    Type: Application
    Filed: August 19, 2013
    Publication date: March 27, 2014
    Applicant: YUAN ZE UNIVERSITY
    Inventors: JEICH MAR, KUEI-CHOU TSAI, YU-TING WANG
  • METHODS AND COMPOSITIONS FOR PRODUCING VITAMIN K DEPENDENT PROTEINS
    Publication number: 20140087458
    Abstract: The present invention relates to methods and compositions for improving the productivity of recombinant vitamin K dependent protein expression in host cells.
    Type: Application
    Filed: November 5, 2013
    Publication date: March 27, 2014
    Applicant: The University of North Carolina at Chapel Hill
    Inventors: Darrel W. Stafford, Tao Li
  • FORWARD-IMAGING OPTICAL COHERENCE TOMOGRAPHY (OCT) SYSTEMS AND PROBES
    Publication number: 20140083970
    Abstract: Provided are forward-imaging optical coherence tomography (OCT) systems and probes.
    Type: Application
    Filed: September 10, 2013
    Publication date: March 27, 2014
    Applicant: Board of Regents, The University of Texas System
    Inventors: Karthik KUMAR, Jonathan C. CONDIT, Nathaniel J. KEMP, Thomas E. MILNER, Xiaojing ZHANG
  • METHOD OF TREATING DISORDER RELATED TO HIGH CHOLESTERAL CONCENTRATION
    Publication number: 20140088060
    Abstract: A method of treating a disorder related to a high cholesterol concentration, comprising administering to a subject in need thereof a compound of formula (I): Also disclosed are methods, kits, combinations, and compositions for treating a disorder in a subject where an activator of liver X alpha is indicated, such as in, for example, treating a high cholesterol disease.
    Type: Application
    Filed: November 27, 2013
    Publication date: March 27, 2014
    Applicant: University of Chicago
    Inventors: Ching Song, Shutsung Liao, Qing Dai
  • FOOT PLATFORM
    Publication number: 20140088479
    Abstract: The therapeutic system of the preferred embodiments includes a foot platform having a lateral segment and a medial segment. The foot platform is coupled to the foot of the patient and supports the body force of the patient. The foot platform functions to move the foot from an equilibrium position to an activated position. The transition of the foot between equilibrium position and activated position, preferably occurs substantially instantaneously once the foot platform supports greater than substantially half of the body force.
    Type: Application
    Filed: March 5, 2013
    Publication date: March 27, 2014
    Applicant: BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
    Inventor: BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
  • ORAL THERAPY OF NECROTIZING ENTEROCOLITIS
    Publication number: 20140086982
    Abstract: The present invention relates to methods of treating or reducing the risk of necrotizing enterocolitis (NEC) in an infant comprising orally administering an effective amount of a CpG-ODN. It is based, at least in part, on the results of experiments in which orally administered CpG-ODNs were observed to reduce the histopathology and markers of inflammation in a murine model for NEC. The present invention further provides for oral formulations of CpG-ODN for administration to infants.
    Type: Application
    Filed: September 25, 2013
    Publication date: March 27, 2014
    Applicant: UNIVERSITY OF PITTSBURGH - OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION
    Inventor: David J. Hackam
  • METHODS OF DETECTING ANEUPLOIDY IN HUMAN EMBRYOS
    Publication number: 20140087376
    Abstract: Methods, compositions and kits for determining the developmental potential of one or more embryos or pluripotent cells and/or the presence of chromosomal abnormalities in one or more embryos or pluripotent cells are provided. These methods, compositions and kits find use in identifying embryos and oocytes in vitro that are most useful in treating infertility in humans.
    Type: Application
    Filed: February 23, 2012
    Publication date: March 27, 2014
    Applicant: The Board Of Trustees of the Leland Stanford Junior University
    Inventors: Shawn L. Chavez, Kevin E. Loewke, Barry Behr, Renee A. Reijo Pera
  • METHOD FOR TREATING NEURODEGENERATIVE TAUOPATHY
    Publication number: 20140086880
    Abstract: The present invention is directed to a filamentous bacteriophage for use in treating a neurodegenerative tauopathy or susceptibility to a neurodegenerative tauopathy and a method of using the bacteriophage for reducing the formation of fibrils of tau protein or for disaggregating pre-formed fibrils of tau protein, such as in a patient suffering from neurodegenerative tauopathy. The filamentous bacteriophage used in the present invention does not display (i) a mammalian cell internalization signal (ii) a ?-amyloid antigen or an antibody to ?-amyloid, or (iii) a tau protein antigen or an antibody to tau protein.
    Type: Application
    Filed: March 12, 2012
    Publication date: March 27, 2014
    Applicant: RAMOT AT TEL-AVIV UNIVERSITY LTD.
    Inventor: Beka Solomon
  • Modified siRNA Molecules Incorporating 5-Fluoro-2'-Deoxyuridine Residues to Enhance Cytotoxicity
    Publication number: 20140088300
    Abstract: A synthesized siRNA molecule having the sense strand with one or more uridine bases replaced by one or more respective nucleoside analogs, such as 5-fluoro-2?-deoxyuridine (FdU).
    Type: Application
    Filed: September 18, 2013
    Publication date: March 27, 2014
    Applicants: University of Pittsburgh - Of the Commonwealth System of Higher Education, U.S. Department of Veterans Affairs
    Inventors: John C. SCHMITZ, SR., Edward Chu, William H. Gmeiner
  • SORAFENIB DERIVATIVES AS SEH INHIBITORS
    Publication number: 20140088156
    Abstract: The present invention provides compounds for the inhibition of soluble epoxide hydrolase and associated disease conditions.
    Type: Application
    Filed: February 14, 2012
    Publication date: March 27, 2014
    Applicant: The Regents of the University of California
    Inventors: Bruce D. Hammock, Sung Hee Hwang, Aaron T. Wecksler, Christophe Morisseau
  • 6,7-DIHYDRO-[1,3,4]THIADIAZOLO-[3,2-a][1,3]DIAZEPIN DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AS HYPNOTIC OR ANESTHETIC AGENT AND METHOD FOR THEIR PREPARATION
    Publication number: 20140088090
    Abstract: The present invention relates to a compound of formula 1, a pharmaceutical composition containing the compound, a method for its preparation as well as the use of the compound as hypnotic agent or anesthetic agent.
    Type: Application
    Filed: April 4, 2012
    Publication date: March 27, 2014
    Applicant: King Saud University
    Inventors: Ghada S. Hassan, Hussein I. El-Subbagh, Mohamed A. Al-Omar, Kamal E.H. El-Taher, Khalid A. Al-Rashood, Abdulrahman M. Al-Obaid, Adel S. El-Azab, Alaa A.M. Abdelaziz, Fatmah A. Al-Omary, Mohamed M. Hefnawy