Patents Assigned to Warner-Lambert Company LLC
  • Process for the synthesis of 1,3-diols
    Patent number: 6962994
    Abstract: An improved process for the preparation of cis-1,3-diols is described where a beta hydroxy ketone is treated with a trialkylborane or dialkylalkoxyborane or a mixture of a trialkylborane and a dialkylalkoxyborane followed by recovery and reuse of the alkylborane species to convert additional beta hydroxy ketone to the cis-1,3-diol.
    Type: Grant
    Filed: April 11, 2003
    Date of Patent: November 8, 2005
    Assignee: Warner-Lambert Company, LLC
    Inventors: Robert Lee Bosch, Richard Joseph McCabe, Thomas Norman Nanninga, Robert Joseph Stahl
  • Solid dosage form dispenser
    Patent number: 6948634
    Abstract: A dispenser for dispensing solid dosing forms which include a storage compartment and a releasing portion at the bottom of the storage compartment. The releasing portion is adapted to receive a releasing device which dispenses a single solid dosage form while providing security against the release of multiple solid dosage forms as well as clogging which may prevent the release of a single solid dosage form.
    Type: Grant
    Filed: March 21, 2002
    Date of Patent: September 27, 2005
    Assignee: Warner-Lambert Company LLC
    Inventors: Christopher T. Evans, Christopher Gieda
  • Cyclodextrins in dental products
    Patent number: 6942848
    Abstract: Oral rinse and dentifrice compositions, comprising a phenolic selected from the group consisting of menthol, eucalyptol, methyl salicylate, thymol, triclosan, and mixtures thereof; and a cyclodextrin selected from the group consisting of hydroxypropyl ?-cyclodextrin, hydroxyethyl ?-cyclodextrin, hydroxypropyl ?-cyclodextrin, hydroxyethyl ?-cyclodextrin, ?-cyclodextrin, methyl ?-cyclodextrin, and mixtures thereof. These compositions are useful in retarding the development of plaque, treating gingivitis, and in treating the presence of micro-organisms in the oral cavity.
    Type: Grant
    Filed: November 21, 2003
    Date of Patent: September 13, 2005
    Assignee: Warner-Lambert Company LLC
    Inventors: Dennis George Anthony Nelson, Craig Joseph Sheehan
  • Process for the synthesis of 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide
    Patent number: 6933393
    Abstract: An improved process for the preparation of 5-(4-fluorophenyl)-1-[2-((2R,4R)-4-hydroxy-6-oxo-tetrahydro-pyran-2-yl)-ethyl]-2-isopropyl-4-phenyl-1H-pyrrole-3-carboxylic acid phenylamide by a novel synthesis is described where methyl cyanoacetate is converted in eight operations or fewer to the desired product, as well as other valuable intermediates used in the process.
    Type: Grant
    Filed: January 21, 2003
    Date of Patent: August 23, 2005
    Assignee: Warner-Lambert Company LLC
    Inventor: Donald Eugene Butler
  • Substituted tropolone compounds, oral care compositions containing the same and methods of using the same
    Patent number: 6924398
    Abstract: The present invention relates to novel tropolone compounds of the present invention and to oral care compositions suitable for preventing or treating diseases or conditions of the oral cavity in warm-blooded animals including humans, comprising an oral care effective amount of at least one novel tropolone compounds, and a pharmaceutically acceptable oral carrier. This invention further relates to a method for preventing or treating diseases or conditions of the oral cavity in warm-blooded animals including humans, by applying an oral care effective amount of the oral care composition to the oral cavity.
    Type: Grant
    Filed: April 19, 2004
    Date of Patent: August 2, 2005
    Assignee: Warner-Lambert Company LLC
    Inventors: Pauline Pan, Marybeth Finnegan, Andre Soshinsky, Georgia Arvanitis, Michael Berardini
  • Cyclohexylamine derivative as subtype selective NMDA receptor antagonists
    Patent number: 6919377
    Abstract: Described are compounds of Formula I and Formula II and their pharmaceutically acceptable salts. The compounds of Formulas I and II are antagonists of NMDA receptor channel complexes useful for treating cerebral vascular disorders such as, for example, cerebral ischemia, cardiac arrest, stroke, and Parkinson's disease.
    Type: Grant
    Filed: April 24, 2001
    Date of Patent: July 19, 2005
    Assignee: Warner Lambert Company LLC
    Inventors: Russell Joseph Deorazio, Sham Shridhar Nikam, Ian Leslie Scott, Brian Alan Sherer, Lawrence David Wise
  • Quinoxalinones as serine protease inhibitors
    Patent number: 6916805
    Abstract: This invention discloses quinoxalinones which display inhibitory effects on serine proteases such as factor Xa, thrombin, and/or factor VIIa. The invention also discloses pharmaceutically acceptable salts and prodrugs of the compounds, pharmaceutically acceptable compositions comprising the compounds, their salts or prodrugs, and methods of using them as therapeutic agents for treating or preventing disease states in mammals characterized by abnormal thrombosis.
    Type: Grant
    Filed: January 4, 2002
    Date of Patent: July 12, 2005
    Assignee: Warner-Lambert Company LLC
    Inventors: Danette Andrea Dudley, Jeremy John Edmunds
  • Pullulan film compositions
    Patent number: 6887307
    Abstract: The invention concerns compositions based on pullulan and a setting system for the use in pharmaceutical, veterinary, food, cosmetic or other products like films for wrapping food, aspics or jellies, preferably for predosed formulations like soft or hard capsules. The composition preferably further contains a surfactant. By using aqueous solution of the inventive compositions, the hard pullulan capsules are produced by a conventional dipping moulding process under the same process condition range than conventional gelatine capsules.
    Type: Grant
    Filed: July 18, 2000
    Date of Patent: May 3, 2005
    Assignee: Warner-Lambert Company, LLC
    Inventors: Robert Scott, Dominique Cade, Xiongwei He
  • Preparation of quinapril hydrochloride
    Patent number: 6858735
    Abstract: Methods and materials for preparing quinapril, its pharmaceutically acceptable salts, including quinapril hydrochloride, are disclosed. The method includes reacting (2S,4S)-2-(4-methyl-2,5-dioxo-oxazolidin-3-yl)-4-phenyl-butyric acid ethyl ester with (3S)-1,2,3,4-tetrahydro-isoquinoline-3-carboxylic acid tert-butyl ester to yield quinapril tert-butyl ester, which is subsequently reacted with an acid to yield quinapril or an acid addition salt of quinapril.
    Type: Grant
    Filed: March 23, 2004
    Date of Patent: February 22, 2005
    Assignee: Warner-Lambert Company LLC
    Inventor: Sandra Marie Jennings
  • Dispenser
    Patent number: D502093
    Type: Grant
    Filed: June 16, 2003
    Date of Patent: February 22, 2005
    Assignee: Warner-Lambert Company LLC
    Inventor: Nicole Enslein
  • Carabiner
    Patent number: D504767
    Type: Grant
    Filed: May 27, 2004
    Date of Patent: May 10, 2005
    Assignee: Warner- Lambert Company LLC
    Inventors: Silvio Joseph DiMarchi, Lawrence P. Scanzillo, Sheng-Fu Lee, Bruce V. Cartier
  • Carabiner
    Patent number: D505257
    Type: Grant
    Filed: May 27, 2004
    Date of Patent: May 24, 2005
    Assignee: Warner-Lambert Company LLC
    Inventors: Silvio Joseph DiMarchi, Lawrence P. Scanzillo, Sheng-Fu Lee, Bruce V. Cartier
  • Dispenser
    Patent number: D505318
    Type: Grant
    Filed: June 16, 2003
    Date of Patent: May 24, 2005
    Assignee: Warner-Lambert Company LLC
    Inventor: Nicole Enslein
  • Tooth-shaped bottle cap
    Patent number: D506673
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: June 28, 2005
    Assignee: Warner-Lambert Company LLC
    Inventors: Bradford Grant, John C. Costello, Alexandre Hennen
  • Receptacle
    Patent number: D507871
    Type: Grant
    Filed: May 27, 2004
    Date of Patent: August 2, 2005
    Assignee: Warner-Lambert Company LLC
    Inventors: Silvio Joseph DiMarchi, Lawrence P. Scanzillo, Sheng-Fu Lee, Bruce V. Cartier
  • Bottle
    Patent number: D507970
    Type: Grant
    Filed: July 30, 2003
    Date of Patent: August 2, 2005
    Assignee: Warner-Lambert Company LLC
    Inventors: Cristina E. Bonaldes, Charles D. Denton, Heath A. Doty, Bryan Holmes, Marc Hunter, Victoria Noble, Randal D. Porter, Kim Sines, John E. Smethers, Russell Wright
  • Tooth-shaped bottle cap
    Patent number: D508403
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: August 16, 2005
    Assignee: Warner-Lambert Company LLC
    Inventors: Bradford Grant, John C. Costello, Alexandre Hennen
  • Tooth-shaped bottle cap
    Patent number: D508404
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: August 16, 2005
    Assignee: Warner-Lambert Company LLC
    Inventors: Bradford A. Grant, John C. Costello, Alexandre Hennen
  • Tooth-shaped bottle cap
    Patent number: D509140
    Type: Grant
    Filed: August 12, 2004
    Date of Patent: September 6, 2005
    Assignee: Warner-Lambert Company LLC
    Inventors: Bradford A. Grant, John C. Costello, Alexandre Hennen
  • Carabiner
    Patent number: D510854
    Type: Grant
    Filed: May 27, 2004
    Date of Patent: October 25, 2005
    Assignee: Warner-Lambert Company LLC
    Inventors: Silvio Joseph DiMarchi, Lawrence P. Scanzillo, Sheng-Fu Lee, Bruce V. Cartier