Patents Assigned to Yissum Research Development Company of the Hebrew University
  • NUCLEIC ACID-CATIONIC POLYMER COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME
    Publication number: 20200138977
    Abstract: Provided herein are pre-lyophilized compositions containing a nucleic acid, a cationic polymer, and a carbohydrate. Also provided are lyophilized compositions of matter and reconstituted compositions as well as methods of making using the same for treating tumors in patients.
    Type: Application
    Filed: January 2, 2020
    Publication date: May 7, 2020
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Abraham HOCHBERG, Jennifer GALLULA
  • HAIR CARE COMPOSITIONS
    Publication number: 20200121581
    Abstract: Provided are methods, compositions and kits employing cellulose nanocrystals for hair-straightening treatment. Also provided are methods, compositions and kits employing a resilin, for hair-straightening treatment and/or for maintenance of straightened hair following a hair-straightening treatment.
    Type: Application
    Filed: April 4, 2018
    Publication date: April 23, 2020
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Smart Resilin Ltd.
    Inventors: Oded SHOSEYOV, Roni SHALEV, Sigal BARUCH-SHARON, Tal BEN SHALOM, Liron NUTTMAN-NESIAL
  • Liposomes comprising polymer-conjugated lipids and related uses
    Patent number: 10624851
    Abstract: The present invention provides liposomes comprising a lipid bilayer and a polymer-conjugated lipid, wherein said polymer-conjugated lipid is incorporated into said lipid bilayer. The present invention also provides methods of producing the liposomes as well as a method of delivering a nucleic acid to a subject comprising the step of administering said nucleic acid encapsulated in a mixed liposome, a method for performing diagnostic imaging in a subject, comprising the step of administering a diagnostic agent encapsulated in a mixed liposome, and methods for treating, inhibiting, or suppressing a pathological condition in a subject comprising administering to said subject a mixed liposome.
    Type: Grant
    Filed: January 14, 2019
    Date of Patent: April 21, 2020
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd
    Inventor: Saul Yedgar
  • Method for storage and release of hydrogen
    Patent number: 10618807
    Abstract: The invention provides a process for the production of hydrogen, comprising catalytically decomposing a concentrated aqueous solution of potassium formate in a reaction vessel to form bicarbonate slurry and hydrogen, discharging the hydrogen from said reaction vessel, and treating a mixture comprising the bicarbonate slurry and the catalyst with an oxidizer, thereby regenerating the catalyst. Pd/C catalysts useful in the process are also described.
    Type: Grant
    Filed: December 28, 2018
    Date of Patent: April 14, 2020
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD.
    Inventors: Yoel Sasson, Harold Wiener, Ariel Givant
  • FATTY ACID AMIDES AND USES THEREOF IN THE TREATMENT OF ADDICTION DISORDER AND ADDICTION RELATED CONDITIONS
    Publication number: 20200108037
    Abstract: The present invention is directed to a fatty acid amide of an amino acid, including a stereoisomer and a salt thereof for use in the treatment of a patient suffering from any type of addiction disorder, substance abuse disorder, including any condition and symptom associated therewith and including withdrawal syndrome and relapse addiction during and after a rehabilitation treatment of said patient.
    Type: Application
    Filed: May 22, 2018
    Publication date: April 9, 2020
    Applicants: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd., VIRGINIA COMMONWEALTH UNIVERSITY, UNIVERSITY OF GUELPH
    Inventors: Raphael MECHOULAM, Vincenzo DI MARZO, Fabiana PISCITELLI, Aron H. LICHTMAN, Imad M. DAMAJ, Linda PARKER, Rami YAKA
  • Isolated polypeptides of CD44 and uses thereof
    Patent number: 10611819
    Abstract: Isolated polypeptides of CD44 are provided. Accordingly, there is provided an isolated polypeptide consisting of an amino acid sequence selected from the group consisting of SEQ ID NOs: 1-3. Also provided is an isolated end-capping modified polypeptide comprising an amino acid sequence selected from the group consisting of SEQ ID NO: 1-3, wherein the modified polypeptide comprises an anti-inflammatory activity. Also provided are compositions of matter, fusion proteins and pharmaceutical compositions and their use in the treatment of inflammatory disease.
    Type: Grant
    Filed: July 15, 2015
    Date of Patent: April 7, 2020
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: David Naor, Lora Eshkar-Sebban, Keren-Or Amar, Shmuel Cohen
  • VAPOR PHASE TREATMENT OF MACROSCOPIC FORMATIONS OF CARBON NANOTUBES
    Publication number: 20200087148
    Abstract: Provided is a composite of a CNT assembly including a plurality of carbon nanotubes (CNTs) and at least one metalcone material, the composite being tunable, by a vapor phase chemical modification, to adopt one or more collective properties selected from mechanical, chemical, physical or electrical properties.
    Type: Application
    Filed: February 21, 2018
    Publication date: March 19, 2020
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventor: Roie YERUSHALMI
  • PROCESSES FOR THE PREPARATION OF HETEROCYCLIC SCAFFOLDS FROM ALPHA ENAMINONES
    Publication number: 20200079738
    Abstract: The present invention provides processes for the preparation of diverse heterocyclic scaffolds from alpha-enaminone building bloc of formula (I).
    Type: Application
    Filed: March 21, 2018
    Publication date: March 12, 2020
    Applicant: Yissum Research Development Company, of The Hebrew University of Jerusalem Ltd.
    Inventor: Dmitry TSVELIKHOVSKY
  • Isolated peptides derived from the B7 ligand dimer interface and uses thereof
    Patent number: 10584157
    Abstract: Disclosed are peptides comprising amino acid residues of the dimer interface of human B7-1 and B7-2 and compositions and uses thereof.
    Type: Grant
    Filed: March 16, 2016
    Date of Patent: March 10, 2020
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD
    Inventors: Raymond Kaempfer, Revital Levy
  • METHOD AND SYSTEM FOR ENHANCING A SPEECH SIGNAL OF A HUMAN SPEAKER IN A VIDEO USING VISUAL INFORMATION
    Publication number: 20200075034
    Abstract: A method and system for enhancing a speech signal is provided herein. The method may include the following steps: obtaining an original video, wherein the original video includes a sequence of original input images showing a face of at least one human speaker, and an original soundtrack synchronized with said sequence of images; and processing, using a computer processor, the original video, to yield an enhanced speech signal of said at least one human speaker, by detecting sounds that are acoustically unrelated to the speech of the at least one human speaker, based on visual data derived from the sequence of original input images.
    Type: Application
    Filed: November 11, 2019
    Publication date: March 5, 2020
    Applicant: Yissum Research Development Company of The Hebrew University of Jerusalem LTD.
    Inventors: Shmuel PELEG, Asaph SHAMIR, Tavi HALPERIN, Aviv GABBAY, Ariel EPHRAT
  • Delivery systems for propofol
    Patent number: 10568834
    Abstract: Provided is a novel dilutable delivery systems and propofol microemulsions suitable for intravenous delivery of propofol.
    Type: Grant
    Filed: June 29, 2016
    Date of Patent: February 25, 2020
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Nissim Garti, Sharon Garti Levi, Abraham Aserin, My Perlstein
  • Peptides for the treatment of malignant proliferative diseases
    Patent number: 10570174
    Abstract: Synthetic peptides containing chemical modifications having anti-tumor properties are provided. Further provided are pharmaceutical compositions including the peptides and use thereof for treating proliferative and neoplastic diseases such as cancer.
    Type: Grant
    Filed: February 7, 2016
    Date of Patent: February 25, 2020
    Assignee: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventor: Uri Wormser
  • CYCLIZATION PROCESSES OF HYDROXYALKENOIC AICDS AND PRODUCTS THEREOF
    Publication number: 20200048233
    Abstract: The invention provides efficient cyclization processes of hydroxyalkenoic acids and products produced therefrom. The following reactions are claimed: Formula (I), (II), (V) and (VI).
    Type: Application
    Filed: February 14, 2018
    Publication date: February 13, 2020
    Applicant: Yissum Research Development Company, of The Hebrew University of Jerusalem Ltd.
    Inventor: Dmitry TSVELIKHOVSKY
  • NEW TOLL-LIKE RECEPTOR 9 ANTAGONISTS
    Publication number: 20200048252
    Abstract: A method of preventing or treating a disease characterized by an excessive immune response in a subject in need thereof is provided. The method includes administering to the subject a composition including an active component, wherein the active component is a first compound, a second compound, a third compound, a pharmaceutically acceptable salt thereof, a solvate thereof, or a combination thereof, wherein the first, second, and third compounds include: respectively.
    Type: Application
    Filed: October 21, 2019
    Publication date: February 13, 2020
    Applicants: FRAUNHOFER-GESELLSCHAFT ZUR FÖRDERUNG DER ANGEWANDTEN FORSCHUNG E.V., YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM, LTD.
    Inventors: Anke BURGER-KENTISCHER, Angela MATTES, Maria ZATSEPIN, Amriam GOLDBLUM
  • COMPRESSED SALT OBJECTS
    Publication number: 20200031714
    Abstract: Provided are objects constructed of compressed salt combinations including salt and at least one additive, wherein the at least one additive is selected to impart the object with resistance to water and humidity.
    Type: Application
    Filed: March 27, 2018
    Publication date: January 30, 2020
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Daniel MANDLER, Noa LAPIDOT, Andrea BUFFA, Gabriel DIKOVSKY, Lihi RIKANATI
  • Method and system for providing deep packet inspection as a service
    Patent number: 10541970
    Abstract: A method and system for providing Deep Packet Inspection (DPI) as a service to a computer network are provided herein. The contribution of embodiments of the present invention is two-folded. First, a possible framework of having DPI deployed as a service is detailed, including the necessary algorithms and required adaptations. Second, the superior performance of the suggested design is demonstrated via simulations. Since the focus is on the algorithmic aspects and network design, an SDN implementation of the suggested design is not provided herein. However, many aspects of such an SDN implementation follow closely the guidelines known in the art.
    Type: Grant
    Filed: June 23, 2015
    Date of Patent: January 21, 2020
    Assignee: Yissum Research Development Company of The Hebrew University of Jerusalem Ltd.
    Inventors: David Hay, Yaron Koral, Yotam Harchol, Anat Brembler-Barr
  • Method for the assay of synucleins
    Patent number: 10534007
    Abstract: The present invention provides a method for the assay of synucleins in a body fluid or tissue sample, wherein said method comprises the steps of contacting said sample with membrane lipids under conditions enabling binding of the synuclein to said lipids, and the detection of the lipid-bound synuclein by a synuclein-binding agent.
    Type: Grant
    Filed: October 7, 2014
    Date of Patent: January 14, 2020
    Assignee: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD
    Inventor: Ronit Sharon
  • FORMULATION AND METHOD FOR INCREASING ORAL BIOAVAILABILITY OF DRUGS
    Publication number: 20200009067
    Abstract: Provided is a formulation and method for increasing bioavailability of an orally administered drug.
    Type: Application
    Filed: September 20, 2019
    Publication date: January 9, 2020
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Amnon HOFFMAN, Abraham J. DOMB, Anna ELGART, Irina CHERNIAKOV
  • CONJUGATES COMPRISING OCULAR ANGIOGENESIS GROWTH FACTOR APTAMERS AND USES THEREOF IN THE DETECTION AND TREATMENT OF OPHTHALMOLOGICAL ANGIOGENESIS INDICATIONS
    Publication number: 20200000934
    Abstract: Provided is an antiangiogenic agent in the form of a vehicle, e.g., a nanoparticle associated (directly or indirectly) with at least one ocular angiogenesis growth factor aptamer, wherein said association labile to interaction between the aptamer and an ocular angiogenesis growth factor.
    Type: Application
    Filed: February 28, 2018
    Publication date: January 2, 2020
    Applicants: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd., Bar Ilan University
    Inventors: Itamar WILLNER, Sharon ETERY, Yossi MANDEL, Amos MARKUS, Asaf SHOVAL
  • HYBRID NANOPARTICLES AS PHOTOINITIATORS
    Publication number: 20190390077
    Abstract: Provided is a novel photoinitiator in the form of a hybrid nanoparticle constructed of a semiconductor and metallic regions, and uses thereof.
    Type: Application
    Filed: August 27, 2019
    Publication date: December 26, 2019
    Applicant: Yissum Research Development Company of the Hebrew University of Jerusalem Ltd.
    Inventors: Uri BANIN, Hermona SOREQ, Shlomo MAGDASSI, Nir WAISKOPF, Yuval BEN-SHAHAR, Amol ASHOK PAWAR, Shira HALIVNI