Abstract: A method for the synthesis of a plurality of oligonucleotides comprising the steps of(i) forming a first oligonucleotide on a first cleavable link attached to a solid support;(ii) attaching to the first oligonucleotide a cleavable linker moiety;(iii) forming a second oligonucleotide on the cleavable linker moiety; and(iv) cleaving the first cleavable link and the cleavable linker moiety to give a plurality of oligonucleotides; wherein the cleavable linker moiety is of the Formula (1): ##STR1## in which A.sup.1, A.sup.2 and E are as defined herein, and novel compounds which may be used in the operation of the method.

Abstract: A herbicidal compound of formula (I) ##STR1## or a salt, tautomer or cyclic derivative thereof; where R.sup.1 and R.sup.2 are hydrogen and A is an optionally substituted saturated or unsaturated chain or ring of three carbon atoms.Methods for preparing these compounds, intermediates used in the preparation and herbicidal compositions containing them are also described and claimed.

Abstract: A compound of the general formula ##STR1## or a salt or complex thereof, in which X, Y and Z are all optionally substituted carbon atoms and R is hydrogen, optionally substituted hydrocarbyl or acyl or --COOR.sup.7 and R.sup.7 is hydrocarbyl has anti-microbial properties. Particular examples are compounds in which X is --CH.sub.2 -- or --C(CH.sub.3).sub.2 -- and Y and Z are both --CH.sub.2 -- or X is is --CH.sub.2 -- and Y and Z are carbon atoms of a benzene ring. The zinc complexes have useful properties.

Abstract: The invention concerns novel, pharmaceutically useful, amide derivatives of certain benzoheterocyclylalkanoic acids (and related tetrazoles and acylsulphonamides) of the formula I and salts thereof, wherein the radicals R.sup.1, R.sup.2, L, X, Y, Z, A.sup.1, Q, A.sup.2 and M have the meanings set out in the specification. The invention also includes pharmaceutical compositions incorporating a formula I compound or a salt thereof, a process for the manufacture of the said compound, together with intermediates for use in the latter process.

Abstract: A liquid crystal display device including two electrically insulating substrates, electrodes on the inner surfaces of the substrates, a film of liquid crystal material contained between the electrodes and a resinous material as sealant and/or encapsulant and/or inner structural component characterised in that the resinous material is the product of light-curing a light-curable resin composition comprising at least one compound having two or more non-aromatic carbon-carbon unsaturated bonds per molecule, at least one compound having two or more mercapto groups per molecule and a photoinitiator.

Abstract: A microbiological process, capable of producing polymers comprising monomer repeat units of the structure--O.CH((CH.sub.2).sub.x CH.sub.3).CH.sub.2.--CO--wherein x is particularly 6 from glucose, novel polymers produced through the process and new strains of Pseudomonas for use in the process.

Abstract: Fruit, especially tomatoes, having lowered expression of fruit-softening enzymes caused by antisense gene expression, and seeds therefrom.

Abstract: An ink containing less than 5% inorganic compounds which comprises a liquid medium and a dye of the Formula (1): ##STR1## wherein: D.sup.1 and D.sup.2 are each independently a chromophore of the azo series;R.sup.1, R.sup.2, R.sup.3 and R.sup.4 are each independently H or optionally substituted alkyl;B is a labile atom or group, hydroxy, amino or an ether, thioether or amine group; andX.sup.1 and X.sup.2 are each independently H, halo, alkyl, alkoxy, acylamino, ureido, nitro, carboxy or sulpho.The inks may be used in ink jet printing either alone or with specified xanthene dyes.

Abstract: The invention concerns oxime derivatives of the formula I ##STR1## wherein R.sup.4 is hydrogen, (1-4C)alkyl, halogeno-(2-4C)alkyl, hydroxy-(2-4C)alkyl, cyano-(1-4C)alkyl, phenyl or phenyl-(1-4C)alkyl; R.sup.5 is hydrogen, (1-4C)alkyl, halogeno-(2-4C)alkyl, hydroxy-(2-4C)alkyl, cyano-(1-4C)alkyl, phenyl or phenyl-(1-4C)alkyl, or a heteroaryl moiety selected from pyridyl, pyrimidinyl, pyrazinyl, pyridazinyl, furyl, thienyl, oxazolyl and thiazolyl;A.sup.4 is (1-4C)alkylene;Ar.sup.1 is phenylene, pyridinediyl or pyrimidinediyl;A.sup.1 is a direct link to X.sup.1 or A.sup.1 is (1-4C)alkylene;X.sup.1 is oxy, thio, sulphinyl or sulphonyl;Ar.sup.2 is phenylene, pyridinediyl, pyrimidinediyl, thiophenediyl, furandiyl or thiazolediyl;R.sup.1 is hydrogen, (1-4C)alkyl, (3-C)alkenyl or (3-4C)alkynyl; andR.sup.2 and R.sup.3 together form a group of the formula --A.sup.2 --X.sup.2 --A.sup.3 -- wherein each of A.sup.2 and A.sup.3 is independently (1-3C)alkylene and X.sup.

Abstract: A polyphenol compound wherein the aromatic rings are linked by direct bonds or by a divalent link in the ortho position relative to the --OH group and the end aromatic rings contain either oximino substituents or substituted alkylaminomethyl substituents in the ortho position. The compound can be coated onto a metal surface to give improved corrosion resistance. The metal surface can be zinc-coated steel or zinc phosphated steel. The polyphenol compound can be the only coating material or can be incorporated into a surface coating composition such as a paint.

Abstract: An ink comprising a liquid medium and a compound of Formula (1) or salt thereof: ##STR1## provided (i) if the compound of Formula (1) has no --SO.sub.3 H groups then it has at least two groups selected from --COOH and --COSH; and (ii) the compound of Formula (1) has at least as many groups selected from --COOH and --COSH as --SO.sub.3 H groups. The inks are useful for ink-jet printing.

Abstract: A process for the preparation of a substituted acetic acid of the Formula (2): ##STR1## wherein --X--Z is an optionally substituted aromatic or heteroaromatic optionally substituted amino radical; by reacting a compound of the Formula (7):Z--Y--H Formula 7with glyoxylic acid. The compounds of Formula (2) are useful as intermediates in the preparation of polycyclic dyes.

Abstract: A water-soluble dye which contains a group of Formula (1): ##STR1## The dyes of Formula (1) can be used to dye materials including natural and artificial textile materials such as wool, silk, polymides and modified polyacrylonitrile fibers.

Abstract: Biocidal isothiazolinone or isothiazolothione compounds are stabilized with an effective amount of a free-radical scavenger compound. Exemplary of the biocidal isothiazolones are 1,2-benzisothiazolin-3-one, 2-methyl-4-5-trimethylene-4-isothiazolin-3-one, 5-chloro-2-methyl-4-isothiazolin-3-one and 2-methyl-4-isothiazolin-3-one. Effective free-radical scavengers include 3,3-thiodipropionic acid.

Abstract: The invention concerns a bicyclic heterocyclic compound of the formula I ##STR1## wherein Q is an optionally substituted 10-membered bicyclic heterocyclic moiety containing 1 or 2 N's and a further O or S heteroatom;A.sup.1 is a direct link to X.sup.1 or (1-3C)alkylene;X.sup.1 is oxy, thio, sulphinyl, sulphonyl or imino;Ar is optionally substituted phenylene or pyridylene;R.sup.1 is (1-4C)alkyl, (3-4C)alkenyl or (3-4C)alkynyl; andR.sup.2 and R.sup.3 together form a group of the formula --A.sup.2 --X.sup.2 --A.sup.3 -- which,together with the carbon atom to which A.sup.2 and A.sup.3 are attached, defines a ring having 5 to 7 ring atoms, wherein each of A.sup.2 and A.sup.3 is (1-3C)alkylene and X.sup.2 is oxy, thio, sulphinyl or sulphonyl; or a pharmaceutically-acceptable salt thereof.The compounds of the invention are inhibitors of the enzyme 5-lipoxygenase.

Abstract: Anti-fungal and anti-microbial bacterial strains of Serratia are used in the preparation and preservation of animal feedstuffs made from forage. Bacterial strains of Serratia rubidaea are particularly useful for such purposes, and permit hay to be baled at higher moisture content. Mixtures of this strain with another anti-fungal bacterial, such as Bacillus subtilis, and/or lactic acid-producing bacterial strains, such as strains of Lactobacillus, Streptococcus, Enterococcus, Lactococcus and Pediococcus are used in the preparation and preservation of silage.

Abstract: Dye compositions and aqueous inks derived therefrom, especially suitable for use in ink jet printing in which the dye composition contains (a) one or more dyes which, in the free acid form, are of Formula (1): ##STR1## wherein W is H or COOH;X is H or COOH;Y is H or COOH;U & Z are each independently H, COOH or SO.sub.3 H; andV is H or SO.sub.3 H;and (b) one or both dyes which in the free acid form is of Formula (2): ##STR2## wherein A is NH.sub.2 and B is OH; orA is OH and B is NH.sub.2.

Abstract: Compounds having the formula (I): ##STR1## and stereoisomers thereof, wherein A is hydrogen, halo, hydroxy, C.sub.1-4 alkyl, C.sub.1-4 alkoxy, C.sub.1-4 haloalkyl, C.sub.1-4 haloalkoxy, C.sub.1-4 alkylcarbonyl, C.sub.1-4 alkoxycarbonyl, phenoxy, nitro or cyano; R.sup.1 and R.sup.2, which may be the same or different, are hydrogen, optionally substituted alkyl, optionally substituted cycloalkyl, optionally substituted heterocyclylalkyl, optionally substituted cycloalkylalkyl, optionally substituted aralkyl, optionally substituted heteroarylalkyl, optionally substituted aryloxyalkyl, optionally substituted heteroaryloxyalkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted alkoxy, optionally substituted aryl, optionally substituted heteroaryl, optionally substituted aryloxy, optionally substituted heteroaryloxy, nitro, halo, cyano, --NR.sup.3 R.sup.4, --CO.sub.2 R.sup.3, --CONR.sup.3 R.sup.4, --COR.sup.3, --S(O).sub.n R.sup.3 wherein n is 0, 1 or 2, (CH.sub.2).sub.m PO(OR.

Abstract: Substituted N-benzotriazoles of the general formula ##STR1## exhibit herbicidal activity. Herbicidal compositions and related methods of using the substituted N-benzotriazoles are also disclosed.

Abstract: The invention concerns cycloalkane derivatives of the formula I ##STR1## wherein Ar.sup.1 is phenyl, naphthyl or a 10-membered bicyclic heterocyclic moiety which may optionally bear up to four substituents;A.sup.1 is a direct link to X.sup.1 or is (1-3C)alkylene;X.sup.1 is oxy, thio, sulphinyl or sulphonyl;Ar.sup.2 is phenylene, pyridylene, pyrimidinylene, thiophenediyl, furandiyl, thiazolediyl or oxazolediyl which may optionally bear one or two substituents;p is 1 to 4;q is 0 to 2;R.sup.1 is hydrogen, (1-4C)alkyl, (2-4C)alkenyl or (3-4C)alkynyl;R.sup.2 is hydrogen, hydroxy, (1-4C)alkyl, (1-4C)alkoxy, (2-4C)alkenyloxy or (3-4C)alkynyloxy;or the OR.sup.1 and R.sup.2 groups together form a (1-4C)alkylenedioxy, oxo, thioxo, imino, hydroxyimino or (1-4C)alkoxyimino group;r is 0 to 3; andR.sup.3 is halogeno, trifluoromethyl or (1-4C)alkyl;or a pharmaceutically-acceptable salt thereof;processes for their manufacture; pharmaceutical compositions containing them and their use as 5-lipoxygenase inhibitors.