Abstract: Systems and methods for developing and applying photosynthetic cellular substances to a human or animal for medical, therapeutic or cosmetic uses are provided. Photosynthetic cells, such as algal cells, can be used in these substances to provide the ability to continuously generate oxygen when exposed to a light source or other oxygen-generating trigger. The substances can be developed as a standalone liquid, gel or cream, or embedded within a bandage, mesh, scaffold or other structure with a light source to promote oxygen production. The substances can be applied topically for medical, therapeutic or cosmetic treatments, or injected internally for generation of oxygen within one or more parts of the body.

Abstract: Embodiments of the present invention comprise a fiber optic guidewire having a hypotube with a plurality of openings that provide variable stiffness and tracking characteristics between at least one proximal segment and one distal segment of the guidewire. In some embodiments, the guidewire further comprises a mandrel disposed within the hypotube, the mandrel cooperating with the optical fibers to permit the distal end of the hypotube to be shaped as desired by a user. Methods of manufacturing and using the guidewire are also disclosed.

Abstract: A tire comprises a tread portion provided with at least one main groove extending continuously in the tire circumferential direction to axially divide the tread portion into land portions. The land portion is provided with axial grooves extending thereacross in the tire axial direction, and each comprising a radially outer portion and a radially inner portion which is wider than the radially outer portion. The radially outer portion of each of the axial grooves is crossed by one ore more sipes.

Abstract: Described is a method and device for dilating a tubular anatomical structure. The device and method can be useful for extracting a blood clot in an artery of a mammal by concentrically irradiating an inner wall of the occluded artery using an ultraviolet (UV) laser beam delivered by an optical fiber having an external or inverted conical tip. Dilation results from photophysical production and release of nitric oxide from the cells lining the arterial wall when UV laser light is projected as a ring beam onto the inner arterial wall. This “minimal contact persistent dilation system” prepares the artery for safer mechanical extraction by thrombectomy, owing to decrease in friction and dissolution of chemical bonding.

Abstract: The invention provides systems and method for the removal of diseased cells during surgery.

Abstract: The device serves for the controlled conveying of a cable. The device has a housing, having a cover plate, on which are externally mounted a drive wheel and contact wheel which can be radially pressed onto the drive wheel, between which the cable can be clamped. The cable can be conveyed by means of the drive wheel being driven by a drive unit in the interior of the housing. The rotational motion of the drive wheel is guided through a stationary light barrier by means of a counting disc, running synchronously therewith and having radial slots or holes in the circumferential area, for determining the motion and rotational speed of the drive wheel. The cover plate and the housing can be sterilized. The drive unit in the interior of the housing is not sterilizable, yet is completely enclosed by the sterilized housing and cover plate.

Abstract: A method of enhancing penetration of a topical composition of 5-aminolevulinic acid (ALA) into tissue for photodynamic therapy includes topically applying ALA to a treatment area to be treated with photodynamic therapy. The method further includes, after the ALA is applied to the treatment area, covering the treatment area with a low density polyethylene barrier. The treatment area is covered with the low density polyethylene barrier prior to light treatment to minimize transepidermal water loss from the treatment area.

Abstract: Robotic and/or surgical devices, systems, and methods include a robotic device. The robotic device includes a manipulator, a drive unit coupled to the manipulator, and a processor coupled with the drive unit. The processor is configured determine that a cannula is mounted to the manipulator and inhibit, using the drive unit, manual articulation of the manipulator in response to determining that the cannula is mounted to the manipulator. In some embodiments, the robotic device further includes a linkage. The processor is further configured to determine a manual effort against the manipulator; inhibit, using the drive unit, the manual articulation of the linkage in response to the manual effort being below an articulation threshold; and facilitate, using the drive unit and in response to not determining that the cannula is mounted to the manipulator, the manual articulation of the linkage in response to the manual effort exceeding the articulation threshold.

Abstract: In an example of a method for reducing oxidation of a build material during three-dimensional printing, a portion of a layer of a polymeric build material is patterned by selectively applying a fusing agent on the portion. A detailing agent selectively applied on a non-patterned portion of the layer. The detailing agent includes a stabilizer to reduce oxidation of the polymeric build material. The layer is exposed to electromagnetic radiation to fuse the portion to form a 3D object layer. The stabilizer at least minimizes discoloration of the non-patterned portion.

Abstract: A system and method for ultraviolet light-mediated hand sanitization and hands-free selection of content presented by a hand sanitizer station. The method includes detecting, using a sensor, an initiation event; responsive to the detection of the initiation event, activating an ultraviolet light source and sanitizing a surface of an object within a compartment adjacent to the ultraviolet light source; and visually presenting a graphic element associated with content on a display for presentation to a user, the display communicatively coupled to the ultraviolet light source.

Abstract: A pneumatic tire is provided with four or more circumferential main grooves extending in a tire circumferential direction and five or more land portions defined by the circumferential main grooves. Additionally, second land portions are each provided with first through lug grooves and second through lug grooves that extend through the second land portion in a tire lateral direction and are adjacently arranged in the tire circumferential direction. Crossing angles of the first through lug grooves and the second through lug grooves with respect to the outermost circumferential main grooves are mutually different.

Abstract: A method for increasing the blood flow and metabolic rate of the eye fundus by (1) irradiating the eye fundus through the pupil by using red light or near-infrared light in a certain wavelength range, a certain energy density range and a certain irradiation time range; (2) once irradiation is complete, repeating the irradiating at intervals of a certain time range, using red light or near-infrared light in the same wavelength range and the same energy density range to irradiate the eye fundus through the pupil.

Abstract: A pneumatic vehicle tire having a tread divided by circumferential grooves, which have a profile depth (T), into block rows running in encircling fashion in a circumferential direction and/or profile ribs which are structured in the manner of profile blocks. Block rows are divided by transverse grooves into blocks and, like the profile ribs structured in the manner of profile blocks, are equipped with blind grooves proceeding from the circumferential grooves. Transverse and/or blind grooves are provided which, owing to a connection of blocks adjacent in the circumferential direction and/or of the block-like structures, have a depth smaller than profile depth (T). The connection has at least two connection steps of different heights, the lowest is formed in each case at the region in which the transverse grooves and/or blind grooves open into the circumferential grooves.

Abstract: A laser eye surgery system includes a laser to generate a laser beam. A spatial measurement system generates a measurement beam and measure a spatial disposition of an eye. A processor is coupled to the laser and the spatial measurement system, the processor comprising a tangible medium embodying instructions to determine a spatial model of the eye in an eye coordinate reference system based on the measurement beam. The spatial model is mapped from the eye coordinate reference system to a machine coordinate reference system. A laser fragmentation pattern is determined based on a plurality of laser fragmentation parameters. The laser fragmentation pattern and the spatial model is rotated by a first rotation angle such that the spatial model is aligned with the reference axis of the machine coordinate reference system and the rotated laser fragmentation pattern is aligned with the corneal incision.

Abstract: A system and computerized method for detection of engagement of a surgical tool to a tool drive of a robotic arm of a surgical robotic system. The method may include activating an actuator of the tool drive to rotate a drive disk to be mechanically engaged with a tool disk in the surgical tool. One or more motor operating parameters of the actuator that is causing the rotation of the drive disk are monitored while activating the actuator. The method detects when the drive disk becomes mechanically engaged with the tool disk, based on the one or more monitored motor operating parameters. Other embodiments are also described and claimed.

Abstract: A tire tread (10) having one or more grooves (201, 202), one or more split bridges (24) arranged in each groove (201, 202), wherein the one or more split bridges (24) having a narrow gap (26) arranged along the width of the corresponding split bridge (24) and extending fully across the length and height of the corresponding split bridge (24), a top side of the one or more split bridges (24) is arranged closest to an outer side (16) of the tread (10), at least a portion of the top side is spaced apart from the outer side (16) of the tread (10) in a direction of a depth of the groove (201, 202) by a variable distance, and a bottom side of the one or more split bridges (24) is spaced apart from a bottom of the groove (201, 202) to form a void between the corresponding split bridge (24) and the bottom of the groove (201, 202).

Abstract: Aspects provide a system including a wearable audio device. The system is configured to determine one or more states of a subject using electrodes positioned on the wearable audio device and in contact with the subject's body. Three electrodes on the wearable audio device are configured to collect any combination of EMG, EOG, ECG/EKG. The system is configured to determine if the subject is fatigued, attentive, anxious, or stressed. The system determines the subject's state without use of a camera. In addition to determining one or more states of the subject, the subject can control the audio device based on a pattern of pupil movements. According to aspects, eye location determined using collected signals are used to adjust and enhance an output of an augmented reality application.

Abstract: The invention is directed to a pneumatic vehicle tire having a tread with profile positives which are separated from one another in a circumferential direction by transverse channels which extend continuously from the central region of the tread to the lateral tread edges and which are main channels of the tread and which, at least over the major part of the course thereof, have the maximum provided profile depth. The tread has, as profile positives, two rows of transverse ribs which are of encircling form in the circumferential direction and which are separated from one another by respective transverse channels. The tread is of directional configuration, wherein the transverse ribs of one row, and thus the transverse channels running between the transverse ribs, run, with respect to the axial direction, oppositely in relation to the transverse ribs and transverse channels of the other row.

Abstract: A pneumatic tire includes a longitudinal protrusion portion provided on at least one of tire side surfaces located on either side in a tire lateral direction, the longitudinal protrusion portion projecting from the tire side surface and extending along the tire side surface; and serration provided on the tire side surface in a region including an end portion of the longitudinal protrusion portion, the serration being formed of a plurality of small grooves arranged in parallel, and the plurality of small grooves being inclined with respect to a lateral centerline that passes through a center of the longitudinal protrusion portion in a width direction.

Abstract: A laser cutting device comprises: a conveying mechanism (1) comprising a feeding end and a discharging end; a working platform (2) disposed at the discharging end of the conveying mechanism (1); a first counter (3) and a second counter (4) oppositely disposed at a side of the working platform (2) near the discharging end of the conveying mechanism (1) and driven respectively by two opposite side edges of a substrate (6) to rotate for counting; a laser cutter (5) disposed above the working platform (2); a control device (13) for determining a modified cutting motion path of the laser cutter according to a set cutting path, and starting and ending times of counting values of the first counter (3) and second counter (4), and for controlling the laser cutter to cut the substrate (6) according to the modified cutting motion path.