Patents Examined by Albert T. Meyers
  • Patent number: 4405645
    Abstract: Cosmetic agents for the control of head dandruff, containing customary cosmetic carrier substances and additives, and 1 to 5% by weight of salts of at least one biguanide derivative of the general formula ##STR1## wherein m is from 1 to 10 and n is from 1 to 6. Preferred salts include oligohexamethylene biguanide, oligotetramethylene biguanide and 1-methyl biguanide. Also preferred are the hydrochloride salts of biguanide derivatives. The agents may be in the form of shampoos, hair lotions, hair setting preparations, rinses, hair dressing gels and creams, hair oils, powders, or sprays. Customary carrier substances may be an ointment base, a powder, water, alcohol or water-alcohol mixtures. Customary cosmetic additives include resins, emulsifiers, thickeners, hair care substances, coloring agents, perfume oils, solid fillers, and propellants.
    Type: Grant
    Filed: March 26, 1981
    Date of Patent: September 20, 1983
    Assignee: Wella Aktiengesellschaft
    Inventors: Rudi Rothlisberger, Friedrich Noser
  • Patent number: 4405613
    Abstract: This invention provides an extract from the plant Maytenus nemerosa (Eckl & Zeyh) Morais (Celastroceae) South Africa and a method of obtaining same. The extract is obtained by subjecting the plant to a series of extraction steps with a plurality of solvents having different polarities. In each extraction step, the solvent used has a polarity higher than that used in the preceding extraction step. All extraction steps are conducted at room temperature. The extracts have been found to possess biological activity.
    Type: Grant
    Filed: July 23, 1982
    Date of Patent: September 20, 1983
    Inventor: Sidney M. Hecht
  • Patent number: 4402698
    Abstract: A process is described which consists, in a first stage, in applying a composition based on a substance of vegetable or animal origin, a synthetic organic substance or a mineral substance, in suspension or in solution in a solvent and having a viscosity suitable for application to the hair, or as a powder, and making it possible to prevent or substantially to limit the passage of the dyestuffs and/or of the dyestuff precursors as far as the scalp, and, in a second stage, in dyeing the hair using one or more compositions, at least one of which contains either an oxidizable dyestuff or a direct dyestuff, the dyeing being followed, after an interval sufficient for coloring the hair, by rinsing and optionally by shampooing.
    Type: Grant
    Filed: December 9, 1980
    Date of Patent: September 6, 1983
    Assignee: L'Oreal
    Inventors: Gregoire Kalopissis, Jacqueline Gallien, Bernard Jacquet, Daniel Bauer, Jean P. Chalaye
  • Patent number: 4396392
    Abstract: Agents for the oxidative dyeing of hair, containing as coloring component 6-amino-3-methylphenol, also in the form of its salts or phenolates. The coloring component is contained in these agents in a quantity of about 0.01 to 2.0 percent by weight, alone or in a mixture with the customary developing and coupling substances. In the case of a mixture, the 6-amino-3-methylphenol is preferably used at a molar ratio below normal relative to these developing and coupling substances. The oxidative reaction of the 6-amino-3-methylphenol proceeding with an intensive yellow coloring is generally not influenced by the customary developing and coupling substances that may be present.
    Type: Grant
    Filed: March 5, 1980
    Date of Patent: August 2, 1983
    Assignee: Wella AG
    Inventors: Eugen Konrad, Herbert Mager
  • Patent number: 4395262
    Abstract: Agents for the oxidative dyeing of hair, containing as coupling substance at least one derivative of 1,2-methylene dioxybenzene of the general formula ##STR1## in which R signifies an OH--, NH.sub.2 --, NHR.sup.1 -- or NR.sup.1 R.sup.2 -group, wherein R.sup.1 and R.sup.2 represent, independently of each other, an alkyl-, hydroalkyl-, or acyl group with 1 to 4 carbon atoms. The coupling substance is contained in these agents in a concentration of about 0.01 to 3.0 percent by weight, i.e. in a mixture with customary developing substances and, in given instances, also customary coupling substances. The particular possibility exists of producing dark natural tints by a mixture of 4-oxy-1,2-methylene dioxybenzene with the developing substance p-aminophenol.
    Type: Grant
    Filed: April 16, 1980
    Date of Patent: July 26, 1983
    Assignee: Wella Aktiengesellschaft
    Inventors: Eugen Konrad, Herbert Mager
  • Patent number: 4395392
    Abstract: A method for decreasing urinary calcium content which comprises orally administering to a person whose urine contains insoluble calcium containing precipitates or has a propensity for forming calcium containing precipitates, an effective amount of an agent selected from water-soluble vinylbenzenesulfonic acid polymers and the nontoxic pharmaceutically acceptable salts thereof.
    Type: Grant
    Filed: June 29, 1981
    Date of Patent: July 26, 1983
    Assignee: Adria Laboratories Inc.
    Inventor: Richard L. Wolgemuth
  • Patent number: 4370338
    Abstract: Anticonvulsant, anxiolytic and hypnotic medicament containing, as active substance, 2-amino-6-trifluoromethoxy-benzothiazole or a salt of this compound with a pharmaceutically acceptable acid.
    Type: Grant
    Filed: October 5, 1981
    Date of Patent: January 25, 1983
    Assignee: Pharmindustrie
    Inventor: Jacques Mizoule
  • Patent number: 4337271
    Abstract: Erythro-9,10-Dihydroxyoctadecan-1-ol acetate, a compound isolated in low yield from tung oil, was synthesized in high yield and found to have excellent potential as a boll weevil feeding deterrent when applied to cotton plants.
    Type: Grant
    Filed: January 28, 1981
    Date of Patent: June 29, 1982
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventor: Martin Jacobson
  • Patent number: 4335130
    Abstract: A mixture of pyrido[3,4-g]isoquinoline (A) and 3,8-phenanthroline (B) in which the ratio of A:B is 37:63 is useful as an antifungal agent.
    Type: Grant
    Filed: May 12, 1981
    Date of Patent: June 15, 1982
    Assignee: Morton-Norwich Products, Inc.
    Inventors: Thomas J. Schwan, Joseph E. Gray
  • Patent number: 4212876
    Abstract: Certain substituted or unsubstituted 2-phenylbenzimidazoles, e.g., 1-methyl-2-phenylbenzimidazole, are useful as anti-obesity agents.
    Type: Grant
    Filed: June 21, 1978
    Date of Patent: July 15, 1980
    Assignee: Sandoz, Inc.
    Inventor: William J. Houlihan
  • Patent number: 4194002
    Abstract: Long chain fatty acid amides of styryl hexahydroindolinols in which the amido portions have ethyleneically unsaturated positions or cyclopropanyl rings, eg 1-(1-oxo-9-cis-octadecenyl)-(3aRS, 4RS, 7aRS)-4-(Z)-(3,4-dimethoxy)-styryl-hexahydro-4-indolinol, are useful as cholesterol ester-reducing agents and are obtainable by reacting corresponding long chain carboxylic acids (or derivatives thereof) with appropriate 4-styryl-4-hexahydroindolinols.
    Type: Grant
    Filed: March 29, 1978
    Date of Patent: March 18, 1980
    Assignee: Sandoz, Inc.
    Inventor: Faizulla G. Kathawala
  • Patent number: 4192888
    Abstract: Pharmaceutical compositions and methods of inhibiting phenylethanolamine N-methyltransferase using 2-indanamine compounds having 4 and/or 5 substituents.
    Type: Grant
    Filed: April 10, 1978
    Date of Patent: March 11, 1980
    Assignee: SmithKline Corporation
    Inventors: William E. Bondinell, Robert G. Pendleton
  • Patent number: 4191772
    Abstract: An instillation composition, comprising an effective amount of at least one sparingly soluble active material suspended or partly dissolved in an aqueous emulsion containing a swelling agent. Advantageously the active substance is nitrofurantoin or a quinolone or pyridazine derivative, the active material has a particle size less than about 10 .mu.m and the swelling agent is a polysaccharide derivative present in about 0.3 to 3% by weight of the composition, the composition further containing at least one local anesthetic, antiphlogistic substance, emulsifier, buffer or stabilizer. With the invention, unit doses of only 50 ml. will contain sufficient active material.
    Type: Grant
    Filed: February 24, 1978
    Date of Patent: March 4, 1980
    Assignee: Boehringer Mannheim GmbH
    Inventors: Heinrich Woog, Werner Rothe, Werner Gruber
  • Patent number: 4191780
    Abstract: Bromhexine derivatives corresponding to the following general formula ##STR1## and antitussive compositions therefrom, as well as a process for making same are described.
    Type: Grant
    Filed: October 16, 1978
    Date of Patent: March 4, 1980
    Assignee: Instituto Franco Tosi S.p.A.
    Inventor: Carlo Tosi
  • Patent number: 4177259
    Abstract: A method of making a water-in-oil waterproof makeup comprising (a) a cosmetic emulsion oil, (b) a cosmetic pigment, and (c) an emulsifier combination comprising (i) a stearate and (ii) a polyhydric alcohol ester of a liquid fatty acid, and compositions therefrom.
    Type: Grant
    Filed: July 14, 1977
    Date of Patent: December 4, 1979
    Assignee: Witco Chemical Corporation
    Inventors: Graham Barker, Martin J. Barabash
  • Patent number: 4177261
    Abstract: There is disclosed a pharmaceutical composition useful in stimulating blood circulation and healing of wounds. This composition comprises (a) albumin-freed calf blood extract, and (b) from about 0.001 to about 2.5 micrograms of at least one kinin per milligram of dry extracted substance. A method for treating patients in order to stimulate their blood circulation is also disclosed. This method comprises treating these patients with an effective amount of the pharmaceutical composition described above.
    Type: Grant
    Filed: December 30, 1977
    Date of Patent: December 4, 1979
    Assignee: Thera Gesellschaft fur Patentverwertung mbH
    Inventors: Gunther Dietze, Matthias Wicklmayr
  • Patent number: 4173566
    Abstract: 1-benzhydryl-2-cyanoazetidine is a novel intermediate for the synthesis of N-diphenylalkyl-2-benzyl azacyclic compounds.
    Type: Grant
    Filed: August 23, 1978
    Date of Patent: November 6, 1979
    Assignee: Schering Corporation
    Inventors: Elijah H. Gold, Daniel M. Solomon
  • Patent number: 4170655
    Abstract: Stable, aqueous or aqueous-alcoholic solutions of fat-soluble perfume oils or drugs, containing hydroxyalkyl ester- and/or N-(hydroxyalkyl)-amide-ethoxylates of the formula ##STR1## wherein R.sub.1 and/or R.sub.2 are an alkyl group having 1 to 18 carbon atoms or hydrogen, R.sub.3 is an alkyl group having 1 to 12 carbon atoms or an aryl group, X is an oxygen atom, the group >NH or the group >N--(C.sub.2 H.sub.4 O).sub.m H, and n and m are integers of from 0 to 40, with the proviso that the total of the carbon atoms of R.sub.1 +R.sub.2 is from 6 to 20 and the total of the numbers n+m is a value from 6 to 40.
    Type: Grant
    Filed: August 19, 1977
    Date of Patent: October 9, 1979
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Ulrich Zeidler, Fanny Scheuermann
  • Patent number: 4167581
    Abstract: 1-Aryloxy-3-aminoalkylamino-2-propanol derivatives, processes for their manufacture, pharmaceutical compositions containing them and methods of using them in the treatment of heart diseases. The compounds possess .beta.-adrenergic blocking activity and some of them additionally possess cardiac stimulant activity. Representative of the compounds disclosed is 1-(2-cyanophenoxy)-3-.beta.(4-hydroxyphenylacetamido)ethylamino-2-propanol .
    Type: Grant
    Filed: November 1, 1978
    Date of Patent: September 11, 1979
    Assignee: Imperial Chemical Industries Limited
    Inventor: Leslie H. Smith
  • Patent number: 4164568
    Abstract: A veterinary composition comprising 40 to 80% of an actively absorbed monosaccharide, 7.5 to 30% of an actively absorbed naturally occurring amino acid, and 0.5 to 10% of an agent which is citric acid or a salt thereof; except that when the agent is a salt of citric acid, then the amino acid represents no more than 13% of the composition; are useful in the treatment of diarrhoea in animals such as calves.
    Type: Grant
    Filed: March 11, 1977
    Date of Patent: August 14, 1979
    Assignee: Beechamgroup Limited
    Inventor: Robert J. Bywater