Abstract: A stable liquid formulation of the pesticide bendiocarb, especially for ultra low volume application, comprises the bendiocarb suspended in a chemically inert oil of low volatility and of low solubility for bendiocarb.
Abstract: The invention relates to cosmetic agents which contain, besides the usual basic cosmetic substances, natural yeast cell contents. The yeast cell contents are obtained by mechanically breaking open the yeast cell walls and by separating off the cell walls and any cell membranes, employing protective conditions. The invention relates also to extracts of yeast cell contents which contain an enriched fraction of yeast cell nuclei and which, when used in cosmetic agents, have an especially good skin-care effect. The native yeast cell contents comprise the cell contents without the cell walls, or the cell contents without cell walls and without nuclear membranes.
Abstract: Hot-water extracts of the neem bark produced by treating the bark of neem with water at a temperature from 0.degree. to 40.degree. C. and subjecting the residue from said pre-extraction treatment to extraction treatment with hot water. Purification of the extract thus produced by means of alcohol precipitation or dialysis gives products of a higher purity. Moreover, treatments prior to the pre-extraction treatment with water at 0.degree.-40.degree. C. with a non-polar organic solvent having a dielectric constant of 10 or lower and a polar organic solvent having a dielectric constant from 15 to 35 yields neem extracts of a further higher purity. The hot-water extracts of the neem bark according to the present invention possess activity against mouse L-5178Y cells and transplanted sarcoma 180 tumors.
Abstract: A lyophilized pharmaceutical solid composition containing cyclophosphamide for reconstitution with water to provide a solution for oral or parenteral administration. This lyophilized cyclophosphamide solid composition demonstrates improved stability, solubility characteristics and enhanced appearance compared with currently available dry powder pre-mix compositions of cyclophosphamide. The lyophilized solid composition contains about 20 parts by weight of cyclophosphamide, about 11/4-2 parts by weight of water and from about 10-85 parts by weight of excipient which is comprised mainly of mannitol. Processes for making the composition are disclosed.
Type:
Grant
Filed:
March 13, 1984
Date of Patent:
August 27, 1985
Assignee:
Mead Johnson & Company
Inventors:
Robert L. Alexander, Robert J. Bequette, Terry T. Kensler, Joseph A. Scott
Abstract: A fungicidal composition containing a fungicidally effective amount of tolchlofos-methyl [O,O-dimethyl O-(2,6-dichloro-4-methylphenyl) phosphorothioate] as an active ingredient, attapulgite clay as a carrier and polypropylene glycol as a stabilizer, its formulation and its use as a fungicide.
Abstract: The invention relates to a method of treating herpes zoster in a patient having herpes zoster wherein an effective amount of capsaicin is topically applied to the area affected with herpes zoster for a time sufficient to relieve the symptoms thereof.
Abstract: A storage-stable highly active muzolimine composition comprising by weight about(a) 100 parts of muzolimine(b) 40-500 parts of starch(c) 20-100 parts of cellulose(d) 0.2-5 parts of silica, and(e) 0.1-3 parts of stearic acid, Ca stearate, Mg stearate and/or talc.
Abstract: Polymeric quaternary ammonium compounds having recurring vinylbenzyl ammonium units are disclosed. The quaternary ammonium units preferably have 2 alkyl substituents of 1 to 4 carbons and 1 alkyl substituent of 4 to 12 carbons. These materials have antimicrobial properties and are particularly useful for preserving ophthalmic solutions.
Type:
Grant
Filed:
September 17, 1984
Date of Patent:
July 30, 1985
Assignee:
Dynapol
Inventors:
Bernard G. Sheldon, Robert E. Wingard, Jr., Ned M. Weinshenker, Daniel J. Dawson
Abstract: An antitoxic galenical composition consisting of an extract of various medicinal herbs and glycerin is provided. This composition is useful in expelling in a short period of time toxic ingredients from the animal body poisoned by toxic materials.
Abstract: A therapeutic composition for reducing blood acetaldehyde level in a patient comprises methionine and a physiologically tolerable carrier. Additionally, potassium citrate and Vitamin B6 may be present in the composition.
Abstract: Surface-active polysiloxanes are disclosed having the formula: ##STR1## in which x denotes an integer from 3 to 10 and A denotes a cationic, anionic, zwitterionic or nonionic hydrophilic unit which contains one or more of the same or different groups which are amine, amine oxide, ammonium, ammonioalkylcarboxylate, ammonioalkylsulphonate, amide, sulphonamide, ether, thioether, sulphoxide, hydroxyl, ester or acid groups. These polysiloxanes are particularly useful for use in cosmetic and pharmaceutical compositions, especially compositions for the hair.
Abstract: A method of isolating material which inhibits virus replication in plants comprising isolating protoplasts from a local lesion-responding tobacco plant having an N gene, preferably a Samsun NN tobacco plant, inoculating the protoplasts with Tobacco Mosaic Virus, and either removing the protoplasts after a predetermined amount of time and isolating the desired material from the protoplast incubation medium, or removing the virus after a predetermined amount of time and isolating the desired material from the preparation.Also provided is a method of isolating material which inhibits virus replication in plants comprising isolating tissue from a "green island" area of a tobacco plant which responds systemically to Cucumber Mosaic Virus, preferably a Samsun NN, a Xanthi-nc or Samsun plant, homogenizing the tissue and isolating the desired material from the homogenate, as well as a method of immunizing plants against virus replication comprising applying thereto the material isolated as above.
Type:
Grant
Filed:
July 15, 1982
Date of Patent:
May 28, 1985
Assignee:
State of Israel, Ministry of Agriculture
Abstract: A process for preparing mangiferin from plants of the genus of Hedysarum (Hedysarum alpinum L., Hedysarum flavescens Rgl. et Schmalh) comprising extraction of xanthone glycosides from the aerial portion of the plants by means of a mixture acetone-water at a volume ratio of the mixture components of 1:0.5-2 respectively; the resulting extract is evaporated, the evaporated extract is filtered. To the filtered evaporated extract sulphuric acid is added to a pH of from 2 to 4, heated at reflux and filtered. The thus-prepared extract is treated with a non-polar organic solvent with the formation of two layers, wherefrom the upper aqueous layer contains xanthone glycosides. This upper layer is treated with butanol with the formation of two layers, wherefrom the upper layer comprises a solution of xanthone glycosides in butanol. This upper butanolic layer is evaporated. The precipitated mangiferin is separated and recrystallized.
Type:
Grant
Filed:
May 16, 1983
Date of Patent:
May 21, 1985
Inventors:
Svetlana V. Rusakova, Vladimir I. Glyzin, Stepan I. Kocherga, Alla A. Ananieva, Larisa F. Libizova
Abstract: A process for reducing the cafestol content of coffee oil in which the coffee oil is initially heated, then extracted with an aqueous isopropanol solution, after which the oil layer is separated from the aqueous isopropanol layer.
Abstract: Method for the treatment of calcifying pancreatitis which comprises administering an effective amount of trimethadione or dimethadione to a patient suffering from calcifying pancreatitis, by which pancreatic stones are effectively dissolved out.
Abstract: Neem bark extracts produced by pre-treating the bark of neem with an organic solvent having a dielectric constant of 10 or lower, for example, benzene or ethyl acetate and subjecting the residue obtained by the pre-treatment to extraction with a hydrophilic organic solvent having a dielectric constant from 15 to 35, for example, methanol or ethanol and recovering the neem bark extracts from the hydrophilic organic extraction solvent.
Abstract: Compounds of the formula ##STR1## wherein A is methylene or carbonyl, n is an integer of 2 to 21, inclusive, and R is hydrogen or lower alkyl, are effective for the prophylaxis or treatment of mammals suffering from fibrosis due to excessive collagen accumulation.