Patents Examined by Albert T. Meyers
  • Patent number: 4621077
    Abstract: Biphosphonic acids of general formula I: ##STR1## in which R is a fluorine atom of a linear or branched alkyl radical containing between 1 and 5 carbon atoms, which may also be substituted by one or more amino groups of fluorine atoms or both amino groups and fluorine atoms, R' is hydroxy or fluorine, and their salts with an alkali metal, an organic base or a basic aminoacid, exhibit valuable properties in the treatment of urolithiasis or in the treatment as inhibitors of bone reabsorption. The compound 4-amino-1-hydroxybutan-1,1-biphosphonic acid is between 100 and 300 times more active than Cl.sub.2 MDP.
    Type: Grant
    Filed: June 8, 1984
    Date of Patent: November 4, 1986
    Assignee: Istituto Gentili S.p.A.
    Inventors: Sergio Rosini, Giorgio Staibano
  • Patent number: 4619923
    Abstract: Method of controlling the rate of tryptophan metabolism in the liver of humans by parenteral administration of tin or chromium protoporphyrin to increase the rate, and the administration of cobalt protoporphyrin to decrease the rate.
    Type: Grant
    Filed: January 14, 1985
    Date of Patent: October 28, 1986
    Assignee: The Rockefeller University
    Inventors: Attallah Kappas, George S. Drummond
  • Patent number: 4618344
    Abstract: Aqueous depilatory compositions containing aminoguanidine and active thiol agent(s) which provide for faster hair removal are disclosed.
    Type: Grant
    Filed: June 1, 1982
    Date of Patent: October 21, 1986
    Assignee: The Procter & Gamble Company
    Inventor: Robert L. Wells
  • Patent number: 4616004
    Abstract: Compounds of the formula: ##STR1## wherein R is aryl or aryl substituted with 1 to 3 substituents independently selected from halogen, lower alkyl of 1 to 4 carbon atoms, lower alkoxy of 1 to 4 carbon atoms, lower alkylthio of 1 to 4 carbon atoms, nitro, cyano, --S(O).sub.n R.sup.2 wherein n is 1 or 2 and R.sup.2 is lower alkyl of 1 to 4 carbon atoms; or alkyl, cycloalkyl, lower alkenyl or lower alkynyl, all optionally substituted with 1 to 3 halogen atoms; and R.sup.1 is lower alkyl, trialkylsilylmethylene, aryldialkylsilylmethylene, aryl; aralkyl, or substituted aryl or aralkyl are fungicidal.
    Type: Grant
    Filed: September 27, 1984
    Date of Patent: October 7, 1986
    Assignee: Chevron Research Company
    Inventor: Laroy H. Edwards
  • Patent number: 4616037
    Abstract: A superior industrial biocide for treating industrial process waters is afforded in the combination of 1,5-pentanedial and methylene bis thiocyanate.
    Type: Grant
    Filed: July 29, 1985
    Date of Patent: October 7, 1986
    Assignee: Nalco Chemical Company
    Inventors: Thomas M. LaMarre, Cynthia H. Martin
  • Patent number: 4613613
    Abstract: A .gamma.-butyrolactone derivative represented by the following formula: ##STR1## wherein R.sup.1 represents a hydrogen atom, a straight or branched alkyl group having 1-8 carbon atoms, a phenyl group; R.sup.2 and R.sup.3 may be the same or different and each represents a hydrogen atom, a straight or branched alkyl group having 1-8 carbon atoms, a cycloalkyl group having 3-10 carbon atoms, a benzyl group, a phenyl group, a phenyl group substituted with a substituent selected from the group consisting of a halogen atom, an alkoxy group, a nitro group, an amino group, an alkyl group having 1-4 carbon atoms, a nitrile group and an alkoxycarbonyl group; R.sup.2 and R.sup.3 may be linked to form an alkylene group having 4-6 carbon atoms; X represents a hydrogen atom, a straight or branched alkyl group having 1-8 carbon atoms, a cycloalkyl group having 3-10 carbon atoms, a benzyl group or a substituent represented by the formula ##STR2## (wherein R.sup.
    Type: Grant
    Filed: September 6, 1984
    Date of Patent: September 23, 1986
    Assignee: Mitsubishi Yuka Pharmaceutical Co., Ltd.
    Inventors: Tomei Oguri, Yasuhiro Morinaka, Shuichiro Kadowaki
  • Patent number: 4613622
    Abstract: Sebosuppressive cosmetic preparations containing benzyl alcohol derivatives which are substituted on the benzene ring by alkyl, aryl, alkyloxymethyl radicals or by a fused aromatic ring, and methods for their use.
    Type: Grant
    Filed: August 30, 1984
    Date of Patent: September 23, 1986
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Hinrich Moeller, Siegfried Wallat
  • Patent number: 4613496
    Abstract: Solid pharmaceutical preparations containing Rifampicin, crystalline cellulose, sodium lauryl sulfate and a lubricant have improved elution properties.
    Type: Grant
    Filed: February 27, 1984
    Date of Patent: September 23, 1986
    Assignee: Ciba-Geigy Corporation
    Inventors: Helmut Kopf, Christian Bucher
  • Patent number: 4612307
    Abstract: The present invention relates to wood rotting fungicidal compositions comprising tolclofos-methyl as an active ingredient.
    Type: Grant
    Filed: November 20, 1985
    Date of Patent: September 16, 1986
    Assignee: Sumitomo Chemical Company, Limited
    Inventor: Tadashi Ooishi
  • Patent number: 4612187
    Abstract: A soft capsule containing as active ingredient .gamma.-oryzanol alone or oryzanol in combination with riboflavin butyrate is described. The shelf life of this composition is increased without precipitation of the ingredients thereof.
    Type: Grant
    Filed: November 6, 1984
    Date of Patent: September 16, 1986
    Assignee: Nisshin Chemicals Co., Ltd.
    Inventors: Takeo Iijima, Hiroyuki Sano
  • Patent number: 4608258
    Abstract: Creosote has a novel pharmaceutical efficacy for treatment of various diseases with diarrhea. The medicament according to the present invention usually contains creosote, coptidis rhizoma, glycyrrhizae radix pulverata, cyperi rhizoma, auranti pericarpium and glycerinum, and it especially consists of 400 mg % of creosote, 200 mg % of coptidis rhizoma, 200 mg % of glycyrrhizae radix pulverata, 150 mg % of cyperi rhizoma, 200 mg % of auranti pericarpium and 100 mg % of glycerinum in each 9 pills.
    Type: Grant
    Filed: August 17, 1983
    Date of Patent: August 26, 1986
    Assignee: Taiko Pharmaceutical Co., Ltd.
    Inventor: Kiyoyuki Yamanaka
  • Patent number: 4605560
    Abstract: A method for obtaining ovipositional disruption of navel orangeworm. The air of nut orchard area, e.g., almonds, where egg-laying by the moth of the navel orangeworm is expected is permeated, as by spraying, by a composition of matter incorporating as an active ingredient as effective amount of crude almond oil. The composition may be a water emulsion of crude almond oil or may be a water emulsion of a wettable powder formulation containing appreciably equal amounts of crude almond oil and ground almond press cake.
    Type: Grant
    Filed: December 4, 1984
    Date of Patent: August 12, 1986
    Assignee: The Regents of The University of California
    Inventors: Robert A. Van Steenwyk, William W. Barnett
  • Patent number: 4604282
    Abstract: A capillary cosmetic composition for the washing and care of the hair comprises in an appropriate cosmetic vehicle an effective amount of at least one extract of sarsaparilla.
    Type: Grant
    Filed: August 27, 1982
    Date of Patent: August 5, 1986
    Assignee: L'Oreal
    Inventors: Jean-Francois Grollier, Josiane Allec
  • Patent number: 4602913
    Abstract: Use of hydroxyanthraquinones for the coloration of human keratin fibres, and process and composition in which they are used.The composition contains, in a cosmetically acceptable medium, at least one hydroxyanthraquinone of the formula: ##STR1## in which R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 independently of one another denote a hydrogen atom, a hydroxyl group, an alkyl group, an alkyl group substituted, for example, by a hydroxyl, amino or acyl group, an alkoxy group, a nitro group, a halogen group, a group SO.sub.3 H, CHO, CO.sub.2 H or SO.sub.3 Na, or a group --CO.sub.2 R', in which R' denotes alkyl or an alkali metal, with the proviso that: at least two of the groups R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 denote hydroxyl, and that if R.sub.1 and R.sub.2 denote OH, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 denoting hydrogen, then at least one of the two groups R.sub.3 and R.sub.4 is different from hydrogen, or alternatively if R.sub.
    Type: Grant
    Filed: July 13, 1984
    Date of Patent: July 29, 1986
    Assignee: L'Oreal
    Inventors: Jean F. Grollier, Georges Rosenbaum, Jean Cotteret
  • Patent number: 4600581
    Abstract: A synthetic pheromone formulated from chemicals found in the airborne secretion of Podisus maculiventris, the spined soldier bug, was found to be highly effective in attracting P. maculiventris, a beneficial predatory insect, to desired areas for biological control of pests.
    Type: Grant
    Filed: December 13, 1984
    Date of Patent: July 15, 1986
    Assignee: The United States of America as represented by the Secretary of Agriculture
    Inventor: Jeffrey R. Aldrich
  • Patent number: 4598096
    Abstract: A method of safely forcing the egress of human beings from a zone by supplying the zone with an irritating amount of 1-methoxy-1,3,5-cycloheptatriene.
    Type: Grant
    Filed: November 6, 1981
    Date of Patent: July 1, 1986
    Inventor: George A. Grant
  • Patent number: 4595592
    Abstract: The present invention provides a process for obtaining laxative compounds from senna drug, wherein(a) the senna drug is extracted with aqueous methanol by countercurrent percolation and the extract concentrated at a temperature of .ltoreq.50.degree. C. until the methanol has been completely removed from the extract;(b) the extract obtained is purified by continuous liquid-liquid extraction with an organic solvent;(c) the refined material (raffinate) obtained is transferred to a crystallization apparatus, acidified, while stirring, to a pH of 1.5 to 2.0, seeded with sennoside crystals, left to crystallize while stirring and the crystalline crude sennoside obtained separated off;(d) whereafter, the crude sennoside are, if desired, recrystallized and optionally converted with a pharmacologically compatible base into a pharmacologically compatible salt.
    Type: Grant
    Filed: November 28, 1984
    Date of Patent: June 17, 1986
    Assignee: Dr. Madaus & Co.
    Inventor: Pentti Hietala
  • Patent number: 4592908
    Abstract: A cream is disclosed for protection of the scalp during hair straightening, composed of 10-80% by weight Vaseline.RTM., and/or polyethylene dissolved in paraffin oil, 10-85% by weight of at least one oxethylated saturated or unsaturated C.sub.8 -C.sub.18 -fatty alcohol and/or oxethylated C.sub.6 -C.sub.14 -alkylphenol each with 2 up to 30 ethylene oxide units in the molecule, 0.5 up to 5.0% by weight of a physiologically compatible organic acid and/or a physiologically compatible, easily saponifiable ester of an organic acid, 0.001 up to 1.0% by weight of at least one pH-indicator and, if necessary, up to 1.0% by weight water as well as, if necessary, customary cosmetic additives. According to the likewise claimed method of straightening hair, the mentioned protective cream is applied to the scalp before the use of an alkaline hair straightening agent. If the alkaline hair straightening agent, subsequently applied to the hair, comes into contact with the protective cream, it is neutralized.
    Type: Grant
    Filed: January 10, 1985
    Date of Patent: June 3, 1986
    Assignee: Wella Aktiengesellschaft
    Inventors: Theodor Wajaroff, Helga Gallist
  • Patent number: 4591605
    Abstract: A method for inhibiting the secretion of stomach acid in vertebrate animals. The method comprises contacting the lumen side of the stomach with a compound which interferes with the acid secretion mechanism yet cannot permeate the lining of the stomach. The compound has a molecular weight of less than 1,200 and at least ten percent of the molecular weight of the compound is due to the molecular weight contribution of secondary amine nitrogen. The invention also includes an ingestible product for inhibiting the secretion of stomach acid in vertebrate animals. The product is ingested so that it is contacted with the lumen side of the stomach to interfere with the acid secretion mechanism without permeating the lining of the stomach. The product contains a compound which has a molecular weight of less than 1200, at least ten percent of the molecular weight of the compound being due to the molecular weight contribution of secondary amine nitrogen.
    Type: Grant
    Filed: October 29, 1982
    Date of Patent: May 27, 1986
    Assignee: Research Foundation of State University of New York
    Inventor: Tushar K. Ray
  • Patent number: 4588590
    Abstract: The present invention includes an improved method of treating keratosis comprising periodically applying to the affected area a nail polish composition containing an effective amount of at least one corrosive agent for relieving the keratosis; also nail polish compositions are disclosed for use in the method.
    Type: Grant
    Filed: January 23, 1984
    Date of Patent: May 13, 1986
    Assignee: Jaye-Boern Laboratories, Inc.
    Inventor: Joel E. Bernstein