Abstract: The present invention relates to a copolymer containing alternating hydrophobic and hydrophilic units and to the use of said copolymers as carrier for active ingredients through a lipid bilayer, especially a lipid membrane.

Abstract: Covalently modified alginate polymers, possessing enhanced biocompatibility and tailored physiochemical properties, as well as methods of making and use thereof, are disclosed herein. The covalently modified alginates are useful as a matrix for coating of any material where reduced fibrosis is desired, such as encapsulated cells for transplantation and medical devices implanted or used in the body.

Abstract: The present invention relates to a hybrid nanodot made by a process comprising a step of reacting a mixture of an amino acid and a polymer selected from polycationic polymers or any copolymers or derivatives of these polymers under hydrothermal reaction conditions. The present invention also relates to a process for synthesizing said hybrid nanodots.

Abstract: The invention relates to the use of molecularly imprinted polymer(s) or MIPs, of odorous molecule(s), as deodorant agent in particular for selectively trapping molecules that are the cause of human body odour. More particularly by using MIPs which may be obtained via polymerization of “sol-gel” type; it being understood that the polymerization is performed in the presence v) of one or more “templates” of target molecule(s) responsible for human body odour. Another subject of the invention concerns a NI process for preparing MIPs as defined previously, MIPs obtained via this process, and a cosmetic composition comprising at least one MIP as defined previously. Unexpectedly, it appears that the MIPs make it possible to specifically trap precursors of odorous molecules and odorous molecules that may be used in cosmetic formulations, especially those that are the cause of the unpleasant odour of sweat.

Abstract: Compositions for delivering one or more active substances, or for repairing a bone, and methods of making and using the same, are described.

Abstract: A minimally invasive controlled drug delivery system for delivering a particular drug or drugs to a particular location of the eye, the system including a porous film template having pores configured and dimensioned to at least partially receive at least one drug therein, and wherein the template is dimensioned to be delivered into or onto the eye.

Abstract: A hair care composition obtainable by blending a conditioning gel phase with an aqueous emulsion of a non-linear organopolysiloxane comprising monomer units of silsesquioxane having a formula (RSiO3/2)n where n=1, R is an alkyl group, preferably methyl, ethyl or propyl, and copolymer segments of polydialkylsiloxane; the conditioning gel phase being formed from a cationic surfactant, a high melting point (25° C. or higher) fatty compound and an aqueous carrier; and the aqueous emulsion of the non-linear organopolysiloxane having an aqueous continuous phase consisting of water and a blend of non-ionic and cationic surfactants and a dispersed phase consisting of the non-linear organopolysiloxane and a hydrocarbon oil, wherein the weight ratio of the non-linear organopolysiloxane to the hydrocarbon oil is 40:60 to 65:35. Alternatively, the aqueous continuous phase consists of water and a cationic surfactant.

Abstract: A disposable wearable absorbent article comprises a chassis having an absorbent core and first and second side panels extending transversally outwards towards respective outer edges. Each of the first and second side panels comprises a mechanical fastening material affixed to an outer end portion of the panel whereby, in use, the first and second side panels can extend around a user's waist to couple the first and second side panels to the chassis. Each of the side panels is gathered in a longitudinal direction to form at least one pleat extending in the transverse direction, and comprises a binding material affixed to respective side panels to maintain each of the first and second side panels in a gathered configuration. A method for forming disposable wearable absorbent articles is also disclosed.

Abstract: This organic group-modified organosilicon resin is represented by the average composition formula (1). (R13SiO1/2)a(R23SiO1/2)b(R33SiO1/2)c(R12SiO2/2)d(R1SiO3/2)e(SiO4/2)f??(1) [a, b, c, d, e and f are numbers that satisfy 0?a?400, 0<b?200, 0?c?400, 0?d?320, 0?e?320, 0<f?1,000, and 0.5?(a+b+c)/f?1.5.] Because this organic group-modified organosilicon resin can form films softer than those formed with trimethylene siloxysilicate, the cosmetic obtained by blending with said silicon resin feels good when used, has good cosmetic holding properties, spreads easily and has an excellent finish, easy removal, and superior scratch resistance.

Abstract: This invention relates to microgel compositions, and in particular, to gel compositions fanned by binding a plurality of individual microgel particles together. The present invention also relates to processes for the preparation of these compositions and their use for particular applications, especially medical applications such as the repair of damaged, degenerated or inappropriately formed load-beating tissue (such as, for example, intervertebral discs).

Abstract: Synthesis of polyionenes with built-in degradable linkers through addition polymerization of a novel class of degradable A2-type monomers (d-A2), and their use as antimicrobial agents are disclosed. A library of biodegradable polyionenes and Gemini-surfactants made from d-A2 monomers are also disclosed. These materials have potent and broad spectrum of antimicrobial activity with high selectivity over mammalian cells.

Abstract: A composition with improved adhesive and sealant properties comprising a) a pre-polymer comprising a polymeric unit of the general formula (-A-B-)n, wherein A represents a substituted or un-substituted ester, B represents a substituted or un-substituted acid ester comprising at least two acid ester functionalities, and n represents an integer greater than 1, and b) an anhydride compound.

Abstract: The present invention relates to a composition for treating keratin fibres, comprising at least an aqueous dispersion of hybrid hydrophobic film-forming acrylic polymer particles, at least one linear block silicone copolymer and at least one amino acid or amino acid derivative.

Abstract: Provided herein are long circulating material free (LCMF) poloxamer compositions and uses thereof. In particular, provided are LCMF poloxamer 188 compositions and uses thereof. Also provided are supercritical fluid extraction (SFE) methods and high pressure (subcritical) methods for preparing poloxamer compositions, particularly the LCMF poloxamer compositions.

Abstract: Liquid-core capsules (10) for pest control are provided, wherein the liquid-core capsules (10) have an aqueous core (11) and a diffusion-inhibiting, functional outer shell (13). The core (11) contains at least one pest control agent. The outer shell (13) contains at least one attractant for the pests.

Abstract: The invention contemplates a copolymer which is a graft or block copolymer useful to change the ocular surface temperature and other characteristics of biological or contact lens surfaces. Methods for use of these formulations and coatings to increase the temperature of the skin, mucous membranes, eye or eyelids will help treat many conditions including blepharitis and non-healing ulcers. Methods to decrease evaporation, improve wettability and stabilize the tear film, and lubricate biological surfaces in a subject, for example, in the treatment of dry eye syndrome, and to improve contact lens tolerability, are provided.

Abstract: Provided is a method for manufacturing a medical sponge for orthopedic treatment by unilateral pressing, which relates to compaction of medical sponges. The method includes a pressing machine that includes a bottom bracket, two vertical support rods, a middle support, a U-shaped support, a drive assembly and two film pressing assemblies. The two vertical support rods are fixed vertically on both ends of the bottom bracket, respectively. The middle support is fixedly arranged on a middle of an upper side of the bottom bracket, and the U-shaped support is fixedly arranged on a top of the middle support. The drive assembly is fixedly arranged on the U-shaped support. The two film pressing assemblies are fixedly arranged between two outer sides of the U-shaped support and the two vertical support rods, respectively.

Abstract: The present invention relates to new classes of monomeric compounds, which may be polymerized to form novel biodegradable and bioresorble polymers and copolymers. These polymers and co-polymers, while not limited thereto, may be adapted for radio-opacity and are useful for medical device applications and controlled release therapeutic formulations.

Abstract: A combination therapy involving different therapeutic molecules can enhance and improve the therapeutic potentials. An effective therapeutic strategy conjugates silica (SiO2) nanoparticles with, e.g., 3-glycidyloxypropyl, trimethoxysilane and azoles, e.g., 1,2,4-triazole (Tri), 3-aminotriazole (ATri), 5-aminetetrazole (Atet), imidazole (Imi). These exemplary materials—classified as SiO2-3GPS-Tri (Conj. 1), SiO2-3GPS-Atri (Conj. 2), SiO2-3GPS-Atet (Conj. 3), SiO2-3GPS-Btri (Conj. 4), and SiO2-3GPS-Imi (Conj. 5)—can amplify targeting of therapeutics for human colorectal carcinoma cells (HCT-116), enhancing anti-cancer effects.

Abstract: The present invention relates to pharmaceutical compositions comprising safinamide and, more particularly, to taste-masked particles comprising said active ingredient or pharmaceutically acceptable salts thereof, oral dosage forms that include said particles and a process for preparing them.