Abstract: This invention relates to novel implant drug delivery systems for long-acting delivery of antiviral drugs. These compositions are useful for the treatment or prevention of human immunodeficiency virus (HIV) infection.
Type:
Grant
Filed:
April 5, 2018
Date of Patent:
August 23, 2022
Assignee:
Merck Sharp & Dohme LLC
Inventors:
Stephanie Elizabeth Barrett, Marian E. Gindy, Li Li, Ryan S. Teller, Seth P. Forster
Abstract: The present invention is directed to a flowable hemostatic paste comprising a crosslinked carboxymethyl cellulose and at least one non-toxic dispersant. More specifically the present invention relates to a hemostatic paste containing citric acid cross-linked CMC, which is suspended or dispersed as a powder in a mixture of a first non-toxic glycerol-containing hygroscopic dispersant and a second non-toxic alcohol functionalized dispersant comprising propylene glycol or 1,3-butanediol.
Type:
Grant
Filed:
June 25, 2020
Date of Patent:
August 16, 2022
Assignees:
Guangzhou Bioseal Co., Ltd., Johnson & Johnson China Ltd., Ethicon Inc.
Abstract: An aqueous composition for making dip-molded comestible hard capsules comprising a film forming capsule base material and one or more colorants each consisting of a hydrophilic coloring foodstuff concentrate.
Type:
Grant
Filed:
February 13, 2020
Date of Patent:
August 9, 2022
Assignee:
Capsugel Belgium NV
Inventors:
Hugues Straub, Stefaan Jaak Vanquickenborne
Abstract: The present invention relates generally to agents and devices for promoting hemostasis and tissue sealing and, more particularly, to hemostatic pads comprising bioabsorbable scaffolds that can deliver lyophilized hemostasis promoting proteins, such as fibrinogen and thrombin, to a wound site or injured organ or tissue.
Type:
Grant
Filed:
February 5, 2020
Date of Patent:
August 2, 2022
Assignee:
Ethicon, Inc.
Inventors:
Randolph W. Hubbell, James Eckhardt, Jerome Riebman, Yufu Li, Michael Elser
Abstract: The inventive subject matter provides kits, compositions and methods for treating or covering skin using a polymerizable formulation. The polymerizable formulation can include a first component including a siloxane polymer and a catalyst, and a second component including a siloxane polymer and a cross-linker. The first and second components, when combined, can form a film or seal having an elasticity that at least one of decreases the formation of fibroblasts, presses down blisters, decreases a biochemical cascade that promotes scar formation, compresses skin, and holds skin in a desired configuration.
Abstract: The present invention relates to a composition based on components of natural origin, in particular ozonized olive oil and liquid vegetable extracts, for the topical treatment of vaginosis and/or vulvovaginitis of bacterial and/or fungal origin.
Abstract: According to one embodiment, a method of managing messages in a trading network is provided. A set of user relationships between a first user and one or more second users authorized to act on behalf of the first user is stored. A trading message regarding a trading order submitted on behalf of the first user is received from a trading system. The trading message is communicated to the first user. Each of the second users is identifying from the set of user relationships. For each of the identified second users, a carrier message is generated that includes the trading message and routing information associated with that second user. For each of the identified second users, the respective carrier message is communicated toward a user application associated with that second user based at least on the routing information included in the respective carrier message.
Abstract: A self-foaming cleansing composition are provided. The self-foaming composition includes a) from about 0.5% to about 10% wt. % of one or more volatile silicone oils; b) from about 0.5% to about 25% wt. % of one or more surfactants stable at low pH; c) from about at least 1.2% of one or more polymers with suspending properties; d) from about 0.5% to about 5% wt % of one or more thickeners; e) from about 0.5% to about 15% wt. % of one organic acid as cosmetic active ingredient; the self-foaming cleansing composition having a pH in between about 3.4 and 5; the self-foaming cleansing composition starting to foam immediately after application of the compositions onto the skin; wherein the foaming cleansing composition is free of perfluoro compound; and wherein the weight percentages are based on the total weight of the self-foaming cleansing composition.
Type:
Grant
Filed:
July 30, 2019
Date of Patent:
June 21, 2022
Assignee:
L'OREAL
Inventors:
Nicholas David Stebbins, Susan Halpern Chirch, Ryuji Hara
Abstract: The present invention relates to a finger-moldable composition capable of forming a free-standing coating and suitable for application to, for example, human lips. The composition includes a thermoplastic block copolymer that includes styrenated blocks. It further includes a sufficient amount of cosmetic oil to allow a human user to mold the composition readily with the user's fingers and form a free-standing film.
Type:
Grant
Filed:
April 30, 2019
Date of Patent:
June 7, 2022
Assignee:
L'OREAL
Inventors:
Andrea E. Schott, Alexandra Farran, Anne-Laure Bernard, Erin McMullin
Abstract: Provided herein is a cosmetic composition comprising gellant technology combined with at least two different gelling agents; neutralizing agent; colorant; and water.
Abstract: Methods for buccally, sublingually, or intranasally administering a prodrug of propofol to a subject in need of treatment thereof in an amount sufficient to deliver a therapeutically effective amount of propofol to the subject are disclosed.
Type:
Grant
Filed:
May 25, 2017
Date of Patent:
May 17, 2022
Assignee:
The Johns Hopkins University
Inventors:
Barbara Slusher, Rana Rais, James Vornov
Abstract: Described herein are pet food compositions comprising: a beta glucan; and a pentacyclic triterpene; wherein the weight ratio of the beta glucan to the pentacyclic triterpene, is about 1:1. Methods of making and using these compositions are also described.
Type:
Grant
Filed:
December 20, 2018
Date of Patent:
May 17, 2022
Assignee:
Hills Pet Nutrition, Inc.
Inventors:
Matthew Jackson, Dennis Jewell, Kiran Panickar
Abstract: Pesticidal mixtures including a pesticidally active compound I selected from: a) compound a) of formula (I). b) compound b) of formula (Ia), c) mixtures comprising compounds a) and b), and at least one further pesticidal active ingredient are disclosed. Methods and use of these mixtures for combating and controlling insects, acarids or nematodes in and on plants, and for protecting such plants being infested with pests are disclosed.
Type:
Grant
Filed:
July 6, 2017
Date of Patent:
May 17, 2022
Assignee:
BASF SE
Inventors:
Robert Reinhard, Tatjana Sikuljak, Pascal Bindschaedler, Karsten Koerber, Juergen Langewald
Abstract: A vitamin supplement composition that includes a complex with enhanced bioavailability having a vitamin B complex, wherein the vitamin B complex includes: (a) a first vitamin, wherein the first vitamin comprises a form of vitamin B6; (b) a second vitamin, wherein the second vitamin comprises a form of vitamin B9; (c) a third vitamin, wherein the third vitamin comprises a form of vitamin B12; and (d) wherein the first vitamin, the second vitamin, and the third vitamin cooperate synergistically to enhance bioavailability of the same. The present invention further includes a method of administering a vitamin supplement composition to an individual having, for example, MTHFR deficiency.
Abstract: The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.
Type:
Grant
Filed:
September 21, 2020
Date of Patent:
April 19, 2022
Inventors:
William H. McKenna, Richard O. Mannion, Edward P. O'Donnell, Haiyong H. Huang
Abstract: The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.
Type:
Grant
Filed:
September 21, 2020
Date of Patent:
April 19, 2022
Inventors:
William H. McKenna, Richard O. Mannion, Edward P. O'Donnell, Haiyong H. Huang
Abstract: The present invention relates to pharmaceutical dosage forms, for example to a tamper resistant dosage form including an opioid analgesic, and processes of manufacture, uses, and methods of treatment thereof.
Type:
Grant
Filed:
September 21, 2020
Date of Patent:
April 12, 2022
Inventors:
William H. McKenna, Richard O. Mannion, Edward P. O'Donnell, Haiyong H. Huang
Abstract: The present invention provides a water-in-oil type emulsion cosmetic which has a fresh and smooth feeling to the touch; forms a uniform coating film once applied; can make skin unevenness such as pores look less prominent while covering discolorations such as age spots and freckles; and does not give an impression of thick application. The water-in-oil emulsion cosmetic is characterized by including (A) 0.1-10% by mass of a pigment-grade titanium dioxide and (B) 0.01-2% by mass of sodium acrylate grafted starch. It is preferred that this cosmetic further includes (C) spherical particles and/or (D) a silicone elastomer.
Abstract: A composite implant comprising a bioabsorbable matrix material, an outer sheath of a textile comprising filaments; and a plurality of flexible reinforcing rods held together by the outer sheath; each of the flexible reinforcing rods have a plurality of filaments, and the filaments of the textile and the flexible reinforcing rods include a degradable or resorbable glass. Preferably, the filaments are present in the composite implant in an amount of 20 volume percent to 95 volume percent, based on the total volume of the composite implant.
Type:
Grant
Filed:
October 18, 2019
Date of Patent:
April 5, 2022
Assignee:
206 ORTHO, Inc.
Inventors:
Jeffrey A. D'Agostino, Andrew J. Carter, Arthur Watterson, Joseph P. Lane