Patents Examined by Choon P. Koh
  • Patent number: 6206912
    Abstract: Methods and apparatus for delivering and installing a new length of tubing between two sections of a patient's existing body organ tubing and at least partly outside of that existing structure. For example, the new length of tubing may be for the purpose of providing the patient with a coronary bypass. The new tubing may be an artificial graft, a natural graft (harvested elsewhere from the patient), or both. The new tubing is delivered to and installed at the operative site primarily by working through the patient's existing tubular body organ structure. This avoids the need for any significant surgery on the patient. The artificial grafts may have shapes other than tubular. Certain procedural and apparatus aspects of the invention have uses other than in connection with grafting in general or tubular grafting in particular.
    Type: Grant
    Filed: August 4, 1999
    Date of Patent: March 27, 2001
    Assignee: St. Jude Medical Anastomotic Technology Group Inc.
    Inventors: David S. Goldsteen, Thomas J. Bachinski, Rudy Mazzocchi, Daniel J. Sullivan
  • Patent number: 6203573
    Abstract: This invention provides molded, biodegradable porous polymeric implant materials having a pore size distribution throughout the material which is substantially uniform. These materials can be molded into implants of any desired size and shape without loss of uniformity of pore size distribution. The implants are useful as biodegradable scaffolds for cell growth in healing of tissue defects. When manufactured to have an aspect ratio greater than about 3, the implants can be further hand-shaped to fit the defect into which they are placed and the desired shape for the regrown tissue.
    Type: Grant
    Filed: January 21, 1999
    Date of Patent: March 20, 2001
    Assignee: OsteoBiologics, Inc.
    Inventors: Mary Ann Walter, Neil C. Leatherbury, Mark Q. Niederauer
  • Patent number: 6203568
    Abstract: The present invention provides an endoluminal prosthesis for deployment in a body lumen of a patient body, the prosthesis comprising a tubular fabric liner and a radially expandable frame supporting the liner. A plurality of imagable bodies are attached to the liner, the imagable bodies providing a sharp contrast so as to define a pattern which indicates the prosthesis position when the prosthesis is imaged within the patient body. Preferably, each imagable body comprises a plate having first and second opposed major surfaces and a passage therebetween to facilitate stitching the imagable body to the liner. Advantageously, the imagable bodies can be aligned with the openings of a perforate frame structure so that at least some of the imagable bodies are visible through associated openings, but need not actually be attached to the frame directly.
    Type: Grant
    Filed: July 24, 1998
    Date of Patent: March 20, 2001
    Assignee: Medtronic, Inc.
    Inventors: Sylvie Lombardi, Steven W. Kim, Darin C. Gittings, Michael A. Evans, Jay A. Lenker, Allan R. Will
  • Patent number: 6203569
    Abstract: A stent is disclosed which comprises generally of ring having, in the preferred embodiment, crossties that have flexibility by having at least one bend. The rings themselves have predetermined stress-relieving points to predispose, by stress relief, particular segments of each ring to bend upon application of an expansion force such as by a balloon or by other means. In the preferred embodiment, the individual rings have notches, reducing the cross-sectional areas at particular locations adjacent reversing bends such that upon radial expansion, bending occurs at these reduced cross-sectional areas to prevent stress from accumulating at the reversing bends.
    Type: Grant
    Filed: June 27, 1997
    Date of Patent: March 20, 2001
    Inventor: Bandula Wijay
  • Patent number: 6203574
    Abstract: A prosthetic bone filler including ceramic granules for use in a living body, the ceramic granules being bonded to each other with a polymeric substance, and having ventilation pores produced as a result of the presence of gaps between the adjacent granules. The prosthetic bone filler is produced by adding the polymeric substance in two portions to the ceramic granules. In addition to good flexibility, the prosthetic bone filler exhibits excellent bio-compatibility.
    Type: Grant
    Filed: April 13, 1999
    Date of Patent: March 20, 2001
    Assignee: Asahi Kogaku Kogyo Kabushiki Kaisha
    Inventor: Katsumi Kawamura
  • Patent number: 6200336
    Abstract: A multiple-sided medical device comprises a closed frame of a single piece of wire or other resilient material and having a series of bends and interconnecting sides. The device has both a flat configuration and a second, folded configuration that comprises a self-expanding stent. The stent is pushed from a delivery catheter into the lumen of a duct or vessel. One or more barbs are attached to the frame of the device for anchoring or to connect additional frames. A covering of fabric or other flexible material such as DACRON, PTFE, or collagen, is sutured or attached to the frame to form an occlusion device, a stent graft, or an artificial valve such as for correcting incompetent veins in the lower legs and feet. A partial, triangular-shaped covering over the lumen of the device allows the valve to open with normal blood flow and close to retrograde flow.
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: March 13, 2001
    Assignee: Cook Incorporated
    Inventors: Dusan Pavcnik, Frederick S. Keller, Josef Rosch, Thomas A. Osborne
  • Patent number: 6200338
    Abstract: A medical implant, tubing and method to provide enhanced X-ray detection intensity in catheters, stents, vascular grafts or other tubular implants. In one aspect the medical implant includes a visually transparent radiopaque polymer and a filler material having a radiopaque component.
    Type: Grant
    Filed: December 31, 1998
    Date of Patent: March 13, 2001
    Assignee: Ethicon, Inc.
    Inventors: Donald D. Solomon, Fidelis C. Onwumere
  • Patent number: 6193745
    Abstract: The present invention provides modular intraluminal tubular prostheses, particularly stents and stent-grafts, for the treatment of disease conditions, particularly aneurysms. Modular sections of the prostheses, or “prosthetic modules,” may be selectively combined to form a composite prosthesis having characteristics which are tailored to the specific requirements of the patient. Each prosthetic module preferably includes one or more standard interface ends for engaging another module, the module/module interface typically comprising ends which overlap and/or lock within a predetermined axial range. Advantageously, the axial length, cross-section, perimeter, resilient expansive force, axial flexibility, liner permeability, liner extensibility, radial conformability, liner/tubal wall sealing and anchoring, and other prosthetic characteristics may be varied along the axis of the composite prosthesis, and also along the axis of each prosthetic module.
    Type: Grant
    Filed: June 4, 1997
    Date of Patent: February 27, 2001
    Assignee: Medtronic, Inc.
    Inventors: Thomas J. Fogarty, Kirsten Freislinger, Steven Weinberg, Brian J. Cox, Michael A. Evans, Steven W. Kim, Jay A. Lenker
  • Patent number: 6193752
    Abstract: A urological implant, in particular a vascular wall support for the urinary tract, is provided with a substantially tubular, inherently stable carrier, a spacer film bonded to the carrier surface, and an inhibitor film of a glycosamino glycan bonded to the spacer film.
    Type: Grant
    Filed: June 29, 1998
    Date of Patent: February 27, 2001
    Inventor: Peter Hildebrandt
  • Patent number: 6190407
    Abstract: A variety of new ways can be used for associating antimicrobial elemental metal with a medical article. The associated antimicrobial metal reduces the risk of infection associated with the medical use of the medical article. New medical articles are produced by some of these new approaches. Some of the methods involve ways of adjusting the dissociation rate of associated elemental metal such that desired degrees of antimicrobial activity can be achieved over selected periods of time.
    Type: Grant
    Filed: December 31, 1998
    Date of Patent: February 20, 2001
    Assignee: St. Jude Medical, Inc.
    Inventors: Matthew F. Ogle, William R. Holmberg, Richard F. Schroeder, Donald S. Guzik, M. William Mirsch, II, Darrin J. Bergman, Hallie A. Finucane, Katherine S. Tweden
  • Patent number: 6190404
    Abstract: The invention relates to an intravascular stent wherein the intravascular stent has its inner surface treated to promote the migration of endothelial cells onto the inner surface of the intravascular stent. Particularly, the inner surface of the intravascular stent includes at least one groove. Methods for manufacturing an intravascular stent are also disclosed.
    Type: Grant
    Filed: November 5, 1998
    Date of Patent: February 20, 2001
    Assignee: Advanced Bio Prosthetic Surfaces, Ltd.
    Inventors: Julio C. Palmaz, Eugene A. Sprague
  • Patent number: 6187047
    Abstract: A porous three-dimensional bone grafting matrix is provided which is biodegradable. The matrix is preferably formed from mineralized collagen where the mineral comprises particulate calcium phosphate immobilized in the matrix and having a particle size of 5 microns or less.
    Type: Grant
    Filed: July 7, 1998
    Date of Patent: February 13, 2001
    Assignee: Orquest, Inc.
    Inventors: Michael K. Kwan, Stephen D. Pacetti, Ronald K. Yamamoto
  • Patent number: 6187044
    Abstract: Compositions and methods are disclosed for filling prostheses for implantation into human soft tissue. The compositions comprise at least one nonionic surfactant, such as a polysorbate, which can be provided to fill a physiologically compatible shell or containment sac of the prosthesis. The liquid compositions of the present invention have a relatively high viscosity and are quickly absorbed from body tissues, metabolized and excreted with no known adverse effect. The compositions can be injected into the physiologically compatible shell either before, during or after the surgical implantation procedure.
    Type: Grant
    Filed: January 7, 1998
    Date of Patent: February 13, 2001
    Assignee: Advanced Research and Technology Institute, Inc.
    Inventor: Barry L. Eppley
  • Patent number: 6187053
    Abstract: In a process for producing a natural implant for tissue of a human or animal body, the body's own cells are multiplied and/or differentiated on a cell base using a culture medium to form the implant.
    Type: Grant
    Filed: November 14, 1997
    Date of Patent: February 13, 2001
    Inventor: Will Minuth
  • Patent number: 6183508
    Abstract: A method for treating a body vessel using a stent formed from filaments of titanium or titanium alloys such as Ti—13Zr—13Nb.
    Type: Grant
    Filed: November 12, 1998
    Date of Patent: February 6, 2001
    Assignee: Schneider Inc
    Inventors: Jonathan S. Stinson, Claude O. Clerc, David W. Mayer
  • Patent number: 6178968
    Abstract: Methods for utilizing a device for blocking (e.g., embolizing) the side branches of an anatomical passageway under endoscopic guidance. The device comprises an elongate catheter body having a side branch blocking apparatus, such as an embolization catheter, disposed therein and further incorporating an endoscope (e.g., an angioscope). The incorporated endoscope is useable to a) visually locate side branches which emanate from the anatomical passageway and b) visually observe the operation of the side branch blocking apparatus. Disclosed are methods for performing in situ embolization of the side branches of a vein, under angioscopic visualization. The endoscopic component of the device may also be utilized to visually observe the use and/or effect of one or more separate device, such as valvulotome(s) used for cutting venous valves located within the lumen of a vein.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: January 30, 2001
    Assignee: Edwards Lifesciences Corp.
    Inventors: Frank Louw, Stephen A. Sosnowski, David Rosenthal
  • Patent number: 6180848
    Abstract: The invention concerns a prosthesis obturating device to obturate a hernial canal comprising, a part (1) made of sheet material for extending through the hernial canal and being characterized in that this first part is extended, at its end that is to be adjacent to the hernial cavity, inside this hernial cavity, by a second part, also made of sheet material and for covering the internal orifice of the hernial canal.
    Type: Grant
    Filed: August 25, 1998
    Date of Patent: January 30, 2001
    Assignees: Ethicon, Inc., Ethicon, S.A.S.
    Inventors: Jean Bernard Flament, Axel Arnaud
  • Patent number: 6176874
    Abstract: Solid free-form fabrication (SFF) methods are used to manufacture devices for allowing tissue regeneration and for seeding and implanting cells to form organ and structural components, which can additionally provide controlled release of bioactive agents, wherein the matrix is characterized by a network of lumens functionally equivalent to the naturally occurring vasculature of the tissue formed by the implanted cells, and which can be lined with endothelial cells and coupled to blood vessels at the time of implantation to form a vascular network throughout the matrix. The SFF methods can be adapted for use with a variety of polymeric, inorganic and composite materials to create structures with defined compositions, strengths, and densities, using computer aided design (CAD). Examples of SFF methods include stereo-lithography (SLA), selective laser sintering (SLS), ballistic particle manufacturing (BPM), fusion deposition modeling (FDM), and three dimensional printing (3DP).
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: January 23, 2001
    Assignees: Masschusetts Institute of Technology, Children's Medical Center Corporation
    Inventors: Joseph P. Vacanti, Linda G. Cima, Michael J. Cima
  • Patent number: 6174329
    Abstract: The invention relates to coated stents and the method of making them. A stent that is substantially radiolucent is at least partially coated with a radiopaque layer that makes the stent visible under X-ray or fluoroscopy. A protective layer is coated on the stent and the radiopaque layer to protect both from scratches, flaking, and galvanic corrosion, and to improve both blood and bio-compatability.
    Type: Grant
    Filed: August 22, 1996
    Date of Patent: January 16, 2001
    Assignee: Advanced Cardiovascular Systems, Inc.
    Inventors: Joseph R. Callol, John Y. Yan
  • Patent number: 6174326
    Abstract: A stent having long-term antithrombogenicity and radiopacity whose location and geometry can be radiographically confirmed is provided. The production method is also provided. The stent of the invention has an antithrombogenic agent covalently bonded on it surface, and the antithrombogenic agent is immobilized onto the stent surface through coupling agent having at least two amino groups and a crosslinking agent having at least two aldehyde and/or epoxy groups. The stent of the invention also has a radiopaque metal plated on at least a part thereof.
    Type: Grant
    Filed: September 23, 1997
    Date of Patent: January 16, 2001
    Assignee: Terumo Kabushiki Kaisha
    Inventors: Takashi Kitaoka, Kazuhiko Hagiwara, Yousuke Moriuchi