Abstract: Systems and methods that enable physiological monitoring with a mobile communication device and that allow detection of motion artifacts so that the results reported are of acceptable quality are disclosed.

Abstract: The present invention relates to an active transdermal analyte detection system performing extraction and detection of body analytes comprising of a patch accepting at least one electrical input; a plurality of transducers configured for converting input electrical energy to different forms of energies for activating extraction procedure; a controller configured for providing the control signals, intensity, sequence, nature, and timing information for the different energies supplied to the said patch vide said transducers; and at least one layer/compartment configured for either collection of extracted fluids and/or delivering at least one reagent formulation that detects the body analyte on activation and a method for performing transdermal extraction and detection of body fluids using said electronic patch.

Abstract: A medical device including an optical sensor is configured to measure an optical signal by integrating a current induced on a light detector of the optical sensor to obtain a voltage signal. The voltage signal is compared to a threshold. Responsive to the voltage signal reaching the threshold, an optical sensor control parameter is adjusted. The optical sensor is operated to produce the voltage signal using the adjusted control parameter.

Abstract: A system for wirelessly monitoring the health of an infant comprising a sensing module removably disposed within a wearable article. At least a portion of the sensing module can be in contact with an infant's foot. The sensing module can include a processing unit configured to receive and process health readings received by the sensing module. A wireless transmitter can also be in communication with the processing unit. The wireless transmitter can be configured to transmit the processed health readings to a receiving station. The receiving station can indicate an alarm if the processed health readings indicate a health trend that falls outside of a particular threshold.

Abstract: Embodiments of the present invention relates to analyte sensors. In particular, the preferred embodiments of the present invention relate to non-consuming intravascular glucose sensors based on fluorescence chemistry.

Abstract: A method and apparatus for non-invasively determining a blood oxygen saturation level and/or the presence of fecal matter within a subject's lower GI tissue is provided. The method includes the steps of: a) providing a spectrophotometric sensor operable to transmit light into the subject's tissue, and to sense the light; b) sensing the subject's lower GI Tissue Using the Sensor, and Producing signal data from sensing the subject's tissue; c) processing the signal data, including determining the presence of one or more wavelength dependent light absorbing materials not present within blood within the subject's lower GI tract from the signal data; and d) determining the blood oxygen saturation level and/or presence of fecal matter within the subject's lower GI tissue, including accounting for the presence of the wavelength dependent light absorbing material not present within blood within the subject's lower GI tract determined using the signal data.

Abstract: A method, a computer readable media and a hand-held device, the hand-held device may include a first sensor that is positioned such as to be contacted by a first hand of a user when the user holds the hand-held device; a second sensor that is positioned such as to be contacted by a second hand of the user when the user holds the hand-held device; wherein at least one sensor of the first sensor and the second sensor is a hybrid sensor that comprises an electrode, an illumination element and a light detector; and a health monitoring module arranged to process detections signals from the electrode and from the light detector such as to provide processed signals that are indicative of a state of the user.

Abstract: The present disclosure relates to a method for estimating blood constituent concentration of a user under low perfusion conditions using a spectrophotometry-based monitoring device; the method comprising: measuring a plurality of photoplethysmographic (PPG) signals; measuring a cardio-synchronous (CV) signal; detecting an instantaneous heart rate and determining a heart rate variability from the CV signal; selecting reliable projected PPG signals; estimating a value of said blood constituent concentration from the magnitude of said reliable projected PPG signals. The disclosed method requires diminished computational load compared to conventional methods based on frequency domain approach as FFT or DCT. The disclosure also pertains to a monitoring device for estimating blood constituent concentration in tissue under low perfusion of a user.

Abstract: A congenital heart disease monitor utilizes a sensor capable of emitting multiple wavelengths of optical radiation into a tissue site and detecting the optical radiation after attenuation by pulsatile blood flowing within the tissue site. A patient monitor is capable of receiving a sensor signal corresponding to the detected optical radiation and calculating at least one physiological parameter in response. The physiological parameter is measured at a baseline site and a comparison site and a difference in these measurements is calculated. A potential congenital heart disease condition in indicated according to the measured physiological parameter at each of the sites or the calculated difference in the measured physiological parameter between the sites or both.

Abstract: A method and system for optical measuring one or more vital signs of a human is described. The method includes generating an optical Pulse Width Modulated (PWM) signal modulated in accordance with a predetermined Pulse Width Modulation scheme. The PWM scheme includes one or more Pulse Width Modulations having different modulation frequencies. The method also includes applying the PWM optical signal to a measurement location in a blood perfused body tissue of the human and receiving light originated back from the measurement location. A photo current signal of a time response of the blood perfused body tissue to the PWM optical signal is indicative of the vital signs. The method includes generating a voltage signal from the photo current signal and processing the voltage signal for determining the vital signs.

Abstract: A system and method are presented for use in monitoring one or more conditions of a subject's body. The system includes a control unit which includes an input port for receiving image data, a memory utility, and a processor utility. The image data is indicative of data measured by a pixel detector array and is in the form of a sequence of speckle patterns generated by a portion of the subject's body in response to illumination thereof by coherent light according to a certain sampling time pattern. The memory utility stores one or more predetermined models, the model comprising data indicative of a relation between one or more measurable parameters and one or more conditions of the subject's body. The processor utility is configured and operable for processing the image data to determine one or more corresponding body conditions; and generating output data indicative of the corresponding body conditions.

Abstract: An apparatus for non-invasive glucose monitoring includes a first light source for emitting at least one ray of first light; a first beam splitter with a focusing function; a set of photo detectors for measuring optical rotatory distribution (ORD) information and absorption energy information of the first light reflected from the eyeball and transmitted through the first beam splitter to the set of photo detectors, and the first light emitted from the first light source being transmitted to the set of photo detectors by the first beam splitter and the eyeball to form an optical path; a processing unit receiving and processing the ORD information and the absorption energy information to obtain glucose information; and an eye positioning device including a second beam splitter disposed on the optical path between the first beam splitter and the eyeball and a camera for receiving image information transmitted from the second beam splitter.

Abstract: Embodiments of devices, methods, and non-transitory computer readable media for monitoring a subject are presented. The monitoring device includes at least one sensor configured to monitor one or more physiological parameters of a subject and a processing unit operatively coupled to the sensor. The sensor comprises a plurality of radiation sources and detectors disposed on a flexible substrate in a designated physical arrangement. The processing unit is configured to dynamically configure an operational geometry of the sensor by controlling the intensity of one or more of the radiation sources and the gain of one or more of the detectors so as to satisfy at least one quality metric associated with one or more physiological parameters of the subject.

Abstract: There is provided a system and method for canceling shunted light. The method includes transmitting electromagnetic radiation at tissue of interest and generating a signal representative of detected electromagnetic radiation. A portion of the generated signal representing shunted light is canceled from the generated signal and the remaining portion of the generated signal is used to compute physiological parameters.

Abstract: An optical sensor unit (10) for measuring a concentration of a gas is provided, comprising at least one sensing layer (122) adapted to be irradiated with a predetermined radiation; at least one gas-permeable layer (121) adjacent to one side of the at least one sensing layer (122) and adapted to pass gas which concentration is to be measured through the gas-permeable layer (121) towards the sensing layer (122); a removable protective layer (150) covering at least the gas-permeable layer (121) and adapted to be removed before use of the optical sensor unit (10), wherein the optical sensor unit (10) is adapted to measure an optical response of the at least one sensing layer (122), which optical response depends on the concentration of the gas.

Abstract: Wearable patches comprising multiple separable adhesive layers. One or more of the layers can comprise electronics, mechanical components, gauze, medicine and/or other types of hardware suitable for the intended use of the patch. In use, a first layer of the patch is adhered to a user. When it is time to change layers, the patch is removed from the user, the first layer is removed from the patch to expose a second adhesive layer, and the second layer is applied to the user. The process may be repeated until the remaining layers of the patch have been used.

Abstract: A device includes source and detector sensors. In a specific implementation, the device has two near detectors, two far detectors, and two sources. The two near detectors are arranged closer to the two sources than the two far detectors. A light-diffusing layer covers the two near detectors. The device may be part of a medical device that is used to monitor or measure oxygen saturation levels in a tissue. In a specific implementation, light is transmitted into the tissue and received by the detectors. An attenuation coefficient is first calculated for a shallow layer of tissue. The attenuation coefficient is then used to calculate an attenuation coefficient for a deep layer of tissue.

Abstract: An active pulse blood constituent monitor is disclosed. A sensor configured to provide an artificial excitation to a portion of the patient at a known frequency provides additional information in determining the physiological condition of the patient.

Abstract: The invention provides a body-worn system that continuously measures pulse oximetry and blood pressure, along with motion, posture, and activity level, from an ambulatory patient. The system features an oximetry probe that comfortably clips to the base of the patient's thumb, thereby freeing up their fingers for conventional activities in a hospital, such as reading and eating. The probe secures to the thumb and measures time-dependent signals corresponding to LEDs operating near 660 and 905 nm. Analog versions of these signals pass through a low-profile cable to a wrist-worn transceiver that encloses a processing unit. Also within the wrist-worn transceiver is an accelerometer, a wireless system that sends information through a network to a remote receiver, e.g. a computer located in a central nursing station.

Abstract: A noninvasive physiological sensor for measuring one or more physiological parameters of a medical patient can include a bump interposed between a light source and a photodetector. The bump can be placed in contact with body tissue of a patient and thereby reduce a thickness of the body tissue. As a result, an optical pathlength between the light source and the photodetector can be reduced. In addition, the sensor can include a heat sink that can direct heat away from the light source. Moreover, the sensor can include shielding in the optical path between the light source and the photodetector. The shielding can reduce noise received by the photodetector.