Patents Examined by D. W. Robinson
  • Method for controlling mites
    Patent number: 4068000
    Abstract: Mite eggs are killed by applying thereto N-tetrachloroethylthio-substituted halomethanesulfonamides of the formula ##STR1## wherein R is alkyl, cycloalkyl, aryl, X is fluoro, chloro, bromo or iodo and R' is tetrachloroethyl.
    Type: Grant
    Filed: August 16, 1976
    Date of Patent: January 10, 1978
    Assignee: Chevron Research Company
    Inventor: Laroy H. Edwards
  • Tetrahydroimidazole compounds useful as pharmaceuticals
    Patent number: 4066778
    Abstract: The present invention relates to new imidazoles, especially of 4- or 5-nitro-imidazoles, substituted by tetrahydroimidazoles which may be substituted and to such compounds which are valuable chemotherapeutica in the treatment of gram-negative bacteria, protozoa and worms.
    Type: Grant
    Filed: June 8, 1976
    Date of Patent: January 3, 1978
    Assignee: Ciba-Geigy Corporation
    Inventors: Kuppuswamy Nagarajan, Vishwa Prakash Arya, Thomas George
  • Soil treatment insecticide
    Patent number: 4065558
    Abstract: This invention relates to a method for controlling the postembryonic development stages of Coleoptera and Diptera inhabiting soil by applying a toxic amount of O,O-diethyl S-(tert-butylthio)methyl phosphorodithioate to said soil in which said insects are living.
    Type: Grant
    Filed: October 20, 1975
    Date of Patent: December 27, 1977
    Assignee: American Cyanamid Company
    Inventor: Fred Morris Gordon
  • Amino acids and esters thereof useful as antihypertensive agents
    Patent number: 4065572
    Abstract: A compound of the formula ##STR1## possesses antihypertensive activity. Also provided are methods for the preparation of the compounds as well as pharmaceutical formulations and methods for their use as antihypertensive agents.
    Type: Grant
    Filed: February 13, 1976
    Date of Patent: December 27, 1977
    Assignee: Merck & Co., Inc.
    Inventors: Joseph George Atkinson, Clarence Stanley Rooney, Yves Girard, Edward L. Engelhardt
  • Heterocyclic-substituted 1,3,5-oxadiazin-2-one compounds useful for combatting coccidiosis
    Patent number: 4064243
    Abstract: New diazine derivatives corresponding to the formula ##STR1## wherein R.sub.1 denotes a heterocyclic-aromatic radical which is optionally substituted by halogen, lower alkyl, aryl, nitro, cyano, trifluoromethyl, carboxyl, R.sub.3 OOC--, (R.sub.3).sub.2 NCO--, (R.sub.3).sub.2 N--, R.sub.3 O--, R.sub.3 SO.sub.2 --, R.sub.3 SO-- or R.sub.3 S--, and R.sub.2 and R.sub.3 independently of one another denote lower alkyl, alkoxyalkyl, alkenyl or cycloalkyl which is optionally bonded via an alkylene bridge, processes for the production of the new compounds, compositions containing these compounds and a process for combating Coccidia.
    Type: Grant
    Filed: May 25, 1976
    Date of Patent: December 20, 1977
    Assignee: Ciba-Geigy Corporation
    Inventors: Roger K. Huff, Jean Jacques Gallay, Manfred Kuhne
  • Substituted 2-(2-hydroxyethyl)tetrahydro-1,4 oxazines and quaternary salts thereof useful for treating spasmodic syndromes
    Patent number: 4062956
    Abstract: 2-(2-Hydroxyethyl)tetrahydro-1,4-oxazines and quaternary salts thereof having the formula: ##STR1## WHEREIN Ar and Ar.sub.1 are the same or different and are unsubstituted and substituted aryl, said substituent being a halogen atom, R represents a lower alkyl group having from 1 to 4 carbon atoms, R.sub.1 is zero when X.sup.(-) is zero or is an alkyl group of from 1 to 4 carbon atoms which is the same or different from R, as defined above, and X.sup.(-) is zero when R.sub.1 is zero or is selected from the group consisting of Cl.sup.(-), Br.sup.(-), I.sup.(-) and CH.sub.3 SO.sub.4.sup.(-) when R.sub.1 is lower alkyl, as defined above, is described. These compounds are useful for treating spasmodic syndromes.
    Type: Grant
    Filed: September 16, 1976
    Date of Patent: December 13, 1977
    Assignee: Centre Europeen de Recherches Mauvernay
    Inventors: Roland Yves Mauvernay, Norbert Busch, Jacques Moleyre, Jacques Simond, Andre Monteil
  • 5,6-Dihydro-4H-1,3-thiazine-2-carboxaldehyde oxime useful as insecticides
    Patent number: 4061749
    Abstract: 5,6-Dihydro-4H-1,3-thiazine-2-carboxaldehyde oxime useful as an insecticide.
    Type: Grant
    Filed: July 6, 1976
    Date of Patent: December 6, 1977
    Assignee: Shell Oil Company
    Inventor: James E. Powell
  • Rapidly resorbable glibenclamide
    Patent number: 4060634
    Abstract: A blood sugar lowering composition comprising as the active material particulate glibenclamide having a surface area of about 3 to 10 m.sup.2 /g in admixture with a pharmacologically acceptable non-ionic wetting agent present in about 2 to 20 times the weight of the glibenclamide. The preferred wetting agent is polyoxyethylene stearate present in about 5 to 10 times the weight of the glibenclamide.
    Type: Grant
    Filed: May 20, 1976
    Date of Patent: November 29, 1977
    Assignee: Boehringer Mannheim G.m.b.H.
    Inventors: Werner Rothe, Helmut Heinemann, Felix Helmut Schmidt, Gunter Betzien
  • O,O-diethyl-O-carboxamidophosphate esters and use to combat insects and mites
    Patent number: 4059699
    Abstract: Mites and insects, particularly aphids, are combated by applying as pest control agents one or more compounds of the structural formula ##STR1## in which R is tert.butylphenyl; tert.butyl; 3,5-dimethylphenyl; 1-methyl-1-phenylthioethyl; 1-methyl-1-methylthioethyl; 1-cyclohexylthio-1-methylethyl; 1-cyclohexylthiopropyl; 1-ethylthio-1-methylethyl; 1-ethylthiopropyl or 1-ethylthioethyl.
    Type: Grant
    Filed: June 7, 1976
    Date of Patent: November 22, 1977
    Assignee: Gulf Oil Corporation
    Inventor: Gary M. Singerman
  • Sulphonated polybenz-1,3-oxazin-2,4-diones
    Patent number: 4059580
    Abstract: Novel, sulphonated polybenz-1,3-oxazin-2,4-diones are produced by reacting polybenzoxazin diones with chlorosulphonic acid in a molar ratio of from 1:1 to 1:10.
    Type: Grant
    Filed: August 10, 1976
    Date of Patent: November 22, 1977
    Assignee: Bayer Aktiengesellschaft
    Inventors: Klaus Elfert, Jurgen Hinz, Rudolf Binsack
  • Fungicidal treatment and composition
    Patent number: 4058600
    Abstract: A method of treating and protecting plants from fungal infections by topical and systemic application with hypophosphites is described. The hypophosphites are selected from the group consisting of hypophosphorous acid (H.sub.3 PO.sub.2) and its salts with monovalent, and multivalent inorganic ions.
    Type: Grant
    Filed: April 28, 1976
    Date of Patent: November 15, 1977
    Assignee: Philagro S.A.
    Inventors: Jean-Claude Debourge, Martine Trochme
  • Method of combatting ticks
    Patent number: 4056631
    Abstract: Method of combatting ticks which comprises applying to the surface of the body of domestic animals an effective amount of a carbodiimide of the formula ##STR1## wherein R represents the specified groups.
    Type: Grant
    Filed: June 8, 1976
    Date of Patent: November 1, 1977
    Assignee: Showa Denko K.K.
    Inventors: Shigeo Kitaoka, Katsuhiro Johkoh, Hisashi Ebisawa, Tadashi Sato, Hiroshi Kubo, Sosuke Takahashi, Yoshinobu Kawase
  • Substituted pyrido[3,4-e]oxazine diones and their therapeutic use
    Patent number: 4054653
    Abstract: Substituted pyrido[3,4-e]oxazine diones, e.g., 6-methyl-4,7-diphenyl-2H-pyrido[3,4-e]-1,3-oxazine-2,5-dione are useful as minor tranquilizers, sleep inducers and muscle relaxants.
    Type: Grant
    Filed: June 1, 1976
    Date of Patent: October 18, 1977
    Assignee: Sandoz, Inc.
    Inventor: Jeffrey Nadelson
  • Phenolic menthene derivatives, therapeutic composition containing same and their use as therapeutic compositions
    Patent number: 4054669
    Abstract: 1-Hydroxy-4-(3'-m.menthen-4'-yl)-benzene, 1-hydroxy-3-methyl-4-(3'-m.menthen-4'-yl)-6-isopropyl-benzene and their sulfonates have antiviral activity against influenza virus and antibacterial activity against gram-positive bacteria.
    Type: Grant
    Filed: January 2, 1976
    Date of Patent: October 18, 1977
    Assignees: Les Derives Resiniques et Terpeniques, S.A. Joullie International
    Inventors: Bernard Lahourcade, Christiane Hirigoyen, Maurice Joullie, Gabriel Maillard, Lucien Lakah, Christian Warolin
  • Method of treating nutritional deficiency during cardiac cachexia, diabetes, hypoglycemia, gastroenterology, lipid, cell glycogen and keratin-related skin conditions and alcoholism
    Patent number: 4053589
    Abstract: A method of treating nutritional deficiency during cardiac cachexia, diabetes, hypoglycemia, gastroenterology, skin conditions related to lipid, cell glycogen and keratin deficiencies and alcoholism which comprises ingestion of a pre-digested protein composition containing all of the essential amino acids and having a palatable taste and odor.
    Type: Grant
    Filed: June 22, 1976
    Date of Patent: October 11, 1977
    Assignee: Control Drug Inc.
    Inventors: Arnold M. Gans, Alvin J. Goren, Eli M. Gorenberg
  • Derivatives of 9,10-dihydroxy-1-(p-alkoxybenzyl)-perhydroisoquinoline oxazine-3-one
    Patent number: 4052389
    Abstract: The disclosed invention is to a compound of the formula: ##STR1## in which R.sup.2 is lower alkyl. These compounds are useful in the preparation of N-substituted-14-hydroxy-3-substituted morphinan derivatives which have been found to possess potent narcotic agonist or antagonist activity.
    Type: Grant
    Filed: March 23, 1976
    Date of Patent: October 4, 1977
    Assignee: Bristol-Myers Company
    Inventors: Ivo Monkovic, Carol Bachand, Henry Wong
  • Insecticidal and insect-repellant methods and compositions
    Patent number: 4049828
    Abstract: Citral is an effective insecticide, nematocide, and insect-repellant. At 1 ppm. it kills 100% of adult moths in two hours. At 0.2% concentration in housefly growth media, it prevents flies from laying eggs. At 0.02% concentration in soil, it reduces the nematode population 99.5%.
    Type: Grant
    Filed: July 14, 1975
    Date of Patent: September 20, 1977
    Inventor: Larry K. Cole
  • Means for killing bacterial spores with glutaraldehyde sporicidal compositions
    Patent number: 4048336
    Abstract: This invention relates to new and improved means for killing spores on instruments and the like utilizing the combination of glutaraldehyde and a monoaldehyde, such as, for example, formaldehyde. The sporicidal kill activity of the composition is more rapid than previously possible, and more effective than the use of either glutaraldehyde or monoaldehyde alone.
    Type: Grant
    Filed: April 23, 1975
    Date of Patent: September 13, 1977
    Assignee: West Chemical Products, Incorporated
    Inventors: Murray A. Winicov, Abraham Cantor
  • Use as insecticides of esters of nitro(tetrahydro-2H-1,3-thiazin-2-ylidene)acetic acids
    Patent number: 4045559
    Abstract: Use as insecticides of esters of nitro(tetrahydro-2H-1,3-thiazin-2-ylidene)acetic acids.
    Type: Grant
    Filed: March 11, 1976
    Date of Patent: August 30, 1977
    Assignee: Shell Oil Company
    Inventor: Steven A. Roman
  • Method of providing high-protein nutrition by the oral administration of a predigested protein composition
    Patent number: 4042688
    Abstract: A mwethod for providing high-protein nutrition, such as to aid the process of body build-up before surgery and of tissue repair after surgery or in other situations where rapid body build-up is desirable, which comprises ingestion of a pre-digested protein composition containing all of the essential amino acids and having a palatable taste and odor.
    Type: Grant
    Filed: June 22, 1976
    Date of Patent: August 16, 1977
    Assignee: Control Drug, Inc.
    Inventors: Arnold M. Gans, Alvin J. Goren, Eli M. Gorenberg