Patents Examined by Djura Malevic
  • Patent number: 11439360
    Abstract: A draping system for use with a medical apparatus, such as a prone breast biopsy system. The draping system may be in the form of a kit ready to be installed on the medical apparatus and may include one or more of a first drape, a second drape, and a third drape. The first drape may include a mat and a protuberance, the mat and the protuberance being coupled together. The protuberance may be configured to receive a paddle mount of the medical apparatus. The mat may have a distal end configured to be secured to a breast support platform of the medical apparatus just below an image receptor. The second drape may include a mat having a distal end configured to be mounted on a compression paddle of the medical apparatus. The third drape may be configured to be inserted over the control panel of the medical apparatus.
    Type: Grant
    Filed: August 16, 2018
    Date of Patent: September 13, 2022
    Assignee: Hologic, Inc.
    Inventor: Thomas W. DeYoung
  • Patent number: 11422094
    Abstract: The analysis of data from fluorescence microscopy is disclosed, more especially fluorescence fluctuation microscopy, being a correlation analysis of fluctuation of the fluorescence intensity enabling quantitative and dynamic information capture. In particular the analysis is described of characteristics such as concentrations, mobility, interactions, stoichiometry, etc. of mixtures of particular that are fluorescently labeled with differently colored fluorophores having different excitation/emission spectra using fluctuation microscopy.
    Type: Grant
    Filed: January 11, 2019
    Date of Patent: August 23, 2022
    Assignees: Universiteit Hasselt, Ludwig-Maximilians-Universität München
    Inventors: Jelle Hendrix, Nick Smisdom, Don Lamb, Waldemar Schrimpf
  • Patent number: 11404469
    Abstract: A flat panel detector is provided, which includes a substrate and a plurality of photodiodes on the substrate. The flat panel detector further includes a first transparent conductive layer disposed on a side of the photodiodes away from the substrate. An orthographic projection of the first transparent conductive layer on the substrate at least partially overlaps the orthographic projection of each photodiode of the plurality of photodiodes on the substrate. The flat panel detector can mitigate or reduce the influence of external static electricity and improve the working stability.
    Type: Grant
    Filed: April 24, 2019
    Date of Patent: August 2, 2022
    Assignees: Beijing BOE Optoelectronics Technology Co., Ltd., BOE Technology Group Co., Ltd.
    Inventors: Yong Zhang, Gang Hua, Yanna Xue, Jian Lin, Zhiying Bao, Lei Mi, Lu Bai, Haobo Fang, Jingpeng Wang, Limin Zhang
  • Patent number: 11385181
    Abstract: Disclosed is a method of determining efficacy of a cosmetic composition to inhibit an atmospheric pollutant from contacting skin, comprising the steps of: (i) filling a sample holder of known dimensions with known amount of said composition to form a layer of defined thickness therein, where said sample holder is amenable to fluorescence-based assay; (ii) depositing, on said layer, a known amount of a model fine particulate matter which resembles an atmospheric pollutant at least in size and which comprises a material responsive to fluorescence microscopy which is excitable by a wavelength (?ex) and which emits radiation (?em) where (?ex)?(?em); (iii) irradiating said composition and said model fine particulate matter by said ?ex and recording intensity of fluorescence at ?em a plurality of times for a defined period during which said model fine particulate matter interacts with said layer; and, (iv) determining, corrected intensity of fluorescence at ?em by the following equation; corrected Intensity=recorde
    Type: Grant
    Filed: September 2, 2019
    Date of Patent: July 12, 2022
    Assignee: CONOPCO, INC.
    Inventors: Yi Fang, Sheng Meng, Shangchun Yi
  • Patent number: 11378515
    Abstract: An image processing device includes: a processor including hardware. The processor is configured to: with respect to each pixel included in a fluorescent image obtained by capturing a tissue group including one or more tissues dyed by using a fluorescent dye group including one or more fluorescent dyes by a fluorescent microscope, estimate a light quantity of fluorescence emitted by each fluorescent dye of the fluorescent dye group; estimate a tissue amount of each tissue of the tissue group based on the estimated light quantity; estimate a virtual dye amount of each dye of a bright-field dye group of a case in which the tissue group dyed by using the bright-field dye group including one or more dyes is captured by a transmission-type microscope based on the estimated tissue amount; and generate a virtual transmitted-light image from the estimated dye amount.
    Type: Grant
    Filed: January 19, 2021
    Date of Patent: July 5, 2022
    Assignee: OLYMPUS CORPORATION
    Inventors: Takeshi Otsuka, Kunio Hori
  • Patent number: 11378714
    Abstract: A method, including emitting from a source of ultrafast neutrons within a logging tool deployed in a borehole, a pulse of ultrafast neutrons into an irradiated portion of a formation surrounding the borehole. The method further includes detecting, with one or more gamma ray detectors located at increasing distances from the source of ultrafast neutrons, a flux of stimulated gamma rays generated within the irradiated portion of the formation by the pulse of ultrafast neutrons; and determining, from the detected flux of stimulated gamma rays, one or more petrophysical properties of the irradiated portion of the formation.
    Type: Grant
    Filed: November 13, 2020
    Date of Patent: July 5, 2022
    Assignee: SAUDI ARABIAN OIL COMPANY
    Inventor: Yahia Ahmed Eltaher
  • Patent number: 11369335
    Abstract: Provided is a radiation image detection device used in a radiation image photographing system including the radiation image detection device that is portable and acquires radiation image data based on irradiated radiation, and a plurality of control terminals that are connected to the radiation image detection device and acquire the radiation image data acquired by the radiation image detection device, the radiation image detection device includes a hardware processor that: transmits and receives communication information to and from each of the control terminals; determines whether an IP address to be used for data communication by a connected one of the control terminals is a dynamic IP address or a static IP address, based on initial information received from each of the control terminals before data communication is established; and acquires an IP address, in accordance with a determination result.
    Type: Grant
    Filed: May 7, 2020
    Date of Patent: June 28, 2022
    Assignee: Konica Minolta, Inc.
    Inventors: Hiroaki Nakano, Naoki Hayashi
  • Patent number: 11353402
    Abstract: A sample observation device includes a sample container that holds the sample stained with a first fluorescent substance and a solution including a second fluorescent substance, an irradiation unit that performs irradiation with first excitation light and second excitation light, a scanning unit that scans the sample container in one direction, an image formation unit that forms first fluorescent light from the sample and second fluorescent light from the solution, an imaging unit that outputs first image data based on the first fluorescent light and first image data based on the second fluorescent light, an image processing unit that generates a first fluorescent light image based on a plurality of pieces of first image data and a second fluorescent light image based on a plurality of pieces of second image data, and an analysis unit that specifies an area in which there is the sample on the basis of the second fluorescent light image and sets an analysis area in the first fluorescent light image.
    Type: Grant
    Filed: April 16, 2018
    Date of Patent: June 7, 2022
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Norikazu Sugiyama, Masanori Matsubara, Satoshi Yamamoto
  • Patent number: 11340359
    Abstract: A detector includes a first detection layer (1141) and a second detector layer (1142). The first and second detection layers include a first and second scintillator (204, 7041) (216, 7042), a first and second active photosensing region (210, 7081) (220, 7082), a first portion (206, 7261) of a first substrate (208, 7061), and a second portion (218, 7262) of a second substrate (208, 7062). An imaging system (100) includes a radiation source (110), a radiation sensitive detector array (108) comprising a plurality of multi-layer detectors (112), and a reconstructor (118) configured to reconstruct an output of the detector array and produces an image. The detector array includes a first detection layer and a second detector layer with a first and second scintillator, a first and second active photosensing region, a first portion of a first substrate, and a second portion of a second substrate.
    Type: Grant
    Filed: April 24, 2018
    Date of Patent: May 24, 2022
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Christoph Herrmann, Roger Steadman Booker, Jakob Wijnand Mulder, Matthias Simon, Jacques Jules Van Oekel
  • Patent number: 11340176
    Abstract: The X-ray inspection apparatus includes an X-ray source, a sample moving mechanism, an X-ray detector equipped with a line sensor with pixels detecting X-ray radiation passing through a sample, an image storage unit for storing X-ray radiation intensities, an intensity correction unit for correcting the X-ray radiation intensities stored in the image storage unit, and a defect detector for detecting a defect in the sample. The intensity correction unit sets an intensity of X-rays detected from the inspection initiation region after starting inspection of the sample or an intensity of X-rays preliminarily detected from the sample before starting the inspection as a reference radiation intensity, and corrects an intensity of X-rays detected from the subsequent inspection region based on a correction coefficient obtained from comparison between the intensity of X-rays detected from the subsequent inspection region and the reference radiation intensity.
    Type: Grant
    Filed: August 21, 2020
    Date of Patent: May 24, 2022
    Assignee: HITACHI HIGH-TECH SCIENCE CORPORATION
    Inventor: Akihiro Takeda
  • Patent number: 11338155
    Abstract: The present disclosure provides a positioning assembly for a radiation irradiation system. The positioning assembly includes a shielding body made of polymer and radiation shielding material capable of shielding the radiation and a sealing bag for accommodating the shielding body, when the target to be irradiated is placed on the positioning assembly, the positioning assembly is recessed with a shape of the target at the position where the target is placed and forms a contour corresponding to the target to position the target to be irradiated.
    Type: Grant
    Filed: May 15, 2019
    Date of Patent: May 24, 2022
    Assignee: NEUBORON MEDTECH LTD.
    Inventor: Ming-chen Hsiao
  • Patent number: 11327018
    Abstract: An image reconstruction method includes capturing a reference image of the specimen and capturing a set of original images based on the reference image. The method includes generating a set of analyzed images based on the set of original images by determining an intensity distribution for each pixel of each original image of the set of original images and combining the intensity distribution at each pixel location across the set of original images into an intermediate image. The method includes, identifying an object in the intermediate image. In response to identifying the object in the intermediate image, determining an intensity value of the object in each original image of the set of original images and generating an improved image of the object based on the determined intensity value of the object. The method includes generating a final image including the improved image of the object and displaying the final image.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: May 10, 2022
    Assignee: THE REGENTS OF THE UNIVERSITY OF MICHIGAN
    Inventors: Somin Eunice Lee, Yunbo Liu, Yipei Wang
  • Patent number: 11327259
    Abstract: A multichip package may include at least a package substrate, a main die mounted on the package substrate, a transceiver die mounted on the package substrate, and an optical engine die mounted on the package substrate. The main die may communicate with the transceiver die via a first high-bandwidth interconnect bridge embedded in the package substrate. The transceiver die may communicate with the optical engine die via a second high-bandwidth interconnect bridge embedded in the package substrate. The transceiver die has physical-layer circuits that directly drive the optical engine. An optical cable can be connected directly to the optical engine of the multichip package.
    Type: Grant
    Filed: December 7, 2017
    Date of Patent: May 10, 2022
    Assignee: Intel Corporation
    Inventors: Peng Li, Joel Martinez, Jon Long
  • Patent number: 11315751
    Abstract: Disclosed herein is an apparatus for electromagnetic x-ray control. The apparatus comprises a thermionic filament, positioned at a first end of a micro-focus x-ray tube and configured to generate an electron stream. The apparatus also comprises an x-ray generation target, positioned within the micro-focus x-ray tube at a second end of the micro-focus x-ray tube, opposite the first end, to receive the electron stream and to generate x-rays in response to the electron stream impinging on the x-ray generation target. The apparatus further comprises an electromagnetic field element, configured to generate an electromagnetic field that receives the electron stream and operable to vary the electromagnetic field to redirect the electron stream, within the micro-focus x-ray tube, to impinge on the x-ray generation target at variable locations on the x-ray generation target. Each one of the variable locations corresponds to a different one of multiple variations of the electromagnetic field.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: April 26, 2022
    Assignee: The Boeing Company
    Inventor: Morteza Safai
  • Patent number: 11307143
    Abstract: A system includes a light source to generate an optical signal having a set of pulses at a first repetition rate. The system also includes a multiplexer circuit to generate a multiplexed optical signal from the optical signal n sets of pulses at a second repetition rate, where the n sets of pulses have different polarization states and are at the first repetition rate. The system also includes a focusing unit to split the multiplexed optical signal into n excitation signals to excite a sample. The system also includes an objective to receive the n excitation signals and to illuminate the sample. The objective and the focusing unit collectively focus each excitation signal of the n excitation signals on a different focal plane of the sample to generate a response signal. The system also includes a demultiplexer circuit to generate n emission signals based on the response signal.
    Type: Grant
    Filed: June 12, 2020
    Date of Patent: April 19, 2022
    Assignee: Allen Institute
    Inventors: Dmitri Tsyboulski, Natalia Orlova, Jerome Anthony Lecoq, Peter Saggau
  • Patent number: 11307311
    Abstract: A dosimeter includes a housing and a printed circuit board positioned within the housing. A silicon photomultiplier is operably connected to the printed circuit board. A scintillator formed of Ce-activated lithium aluminosilicate glass is positioned on the silicon photomultiplier. An optical coupling is positioned between the scintillator and the silicon photomultiplier, and an optical reflector surrounds the scintillator.
    Type: Grant
    Filed: October 22, 2019
    Date of Patent: April 19, 2022
    Assignee: THERMO FISHER SCIENTIFIC MESSTECHNIK GMBH
    Inventors: Erich Leder, Michael Iwatschenko-Borho, Norbert Trost, Reinhard Buchhold
  • Patent number: 11291726
    Abstract: The present invention relates to near-infrared-absorbing dye-based composite particles which exhibit a photothermal effect and/or photoacoustic signal upon photoirradiation, a preparation method thereof, and a use thereof. The near-infrared-absorbing composite particles comprise: a water-insoluble salt of a near-infrared-absorbing dye, which comprises anions of the near-infrared-absorbing dye and metal cations capable of forming a precipitation product with the anions of the near-infrared-absorbing dye; and particles of a polymeric surfactant, in which a water-insoluble salt of the near-infrared-absorbing dye is supported in the hydrophobic part of the polymeric surfactant.
    Type: Grant
    Filed: April 26, 2019
    Date of Patent: April 5, 2022
    Assignee: KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Sehoon Kim, Youngsun Kim, Keunsoo Jeong, Gayoung Kim
  • Patent number: 11262298
    Abstract: A system for determining an origin of a fluid from a machine may include a spectral measurement device configured to generate spectral data for a fluid, and a transmitter in communication with the spectral measurement device and configured to transmit the spectral data. The system may also include a receiver in communication with the transmitter and configured to receive a transmission indicative of the spectral data from the transmitter. The system may further include a processor in communication with the receiver and configured to cause execution of an analytical model configured to determine, based at least in part on the spectral data, fluidic information related to the fluid, the fluidic information including an indication of an origin of the fluid. The system may also include an output device in communication with the processor and configured to output the indication of the origin of the fluid.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: March 1, 2022
    Assignee: Caterpillar Inc.
    Inventors: Benjamin John Hodel, Cynthia Marie Mann Rohde
  • Patent number: 11255785
    Abstract: Methods, systems, and apparatus, including computer programs encoded on a computer storage medium, for obtaining a fluorescence microscope image that depicts a sample and a plurality of fiducial markers, identifying the plurality of fiducial markers in the image, and using the plurality of fiducial markers to register the image. The sample and the plurality of fiducial markers have a common fluorescence color, and identifying the plurality of fiducial markers in the image includes comparing a spatial intensity distribution of a plurality of fluorescent regions of the image to a reference distribution function.
    Type: Grant
    Filed: March 12, 2020
    Date of Patent: February 22, 2022
    Assignee: Applied Materials, Inc.
    Inventor: Yun-Ching Chang
  • Patent number: 11253212
    Abstract: The present disclosure relates to the use of X-ray detector cassettes that may be abutted or overlapped to form a detector assembly suitable for imaging objects that are too large to image using a single X-ray detector cassette. Such a detector assembly may be customized in terms of the size and/or shape of the field-of-view (FOV). In certain embodiments the radiation-sensitive electronics (e.g., readout electronics) are positioned to the side of the X-ray detecting components (e.g., scintillator, TFT array, and so forth), allowing the cassette to be thin relative to other detector devices and allowing the electronics to remain outside the X-ray beam path.
    Type: Grant
    Filed: January 7, 2020
    Date of Patent: February 22, 2022
    Assignee: GENERAL ELECTRIC COMPANY
    Inventors: Biju Jacob, Douglas Albagli, William Robert Ross, William Andrew Hennessy, Eric Patrick Davis, Bruno Kristiaan Bernard De Man, Nicholas Ryan Konkle