Abstract: The present invention relates to a sensor applicator assembly for a continuous glucose monitoring system and provides a sensor applicator assembly for a continuous glucose monitoring system, which is manufactured with a sensor module assembled inside an applicator, thereby minimizing additional work by a user for attaching the sensor module to the body and allowing the sensor module to be attached to the body simply by operating the applicator, and thus can be used more conveniently. A battery is built in the sensor module and a separate transmitter is connected to the sensor module so as to receive power supply from the sensor module and be continuously used semi-permanently, thereby making the assembly economical. The sensor module and the applicator are used as disposables, thereby allowing accurate and safe use and convenient maintenance.

Abstract: A wearable patient device is provided that includes one or more sensors. The one or more sensors can record one or both of ECG information or phonocardiographic information. The sensor information can be used to determine the blood pressure of a monitored individual, including on a continuous basis. Blood pressure can be determined using one or both of a determined time to empty or fill one or more heart chambers or first and second blood velocities. Vital sign information can be provided to a monitoring individual, including graphical representations of trend information.

Abstract: A blood glucose detection device includes a carrier body, a flow-guiding actuator, a microneedle patch, a sensor and a controlling chip. The carrier body has a liquid guiding channel, a compressing chamber and a liquid storage chamber. The flow-guiding actuator seals the compressing chamber. The microneedle patch is attached on the carrier body and has plural hollow microneedles. The sensor is disposed within the liquid storage chamber. The controlling chip is disposed on the carrier body. The plural hollow microneedles puncture the skin of a human subject with minimal invasion. The controlling chip controls the flow-guiding actuator to actuate and the tissue fluid is sucked into the liquid storage chamber through the plural hollow microneedles, whereby the sensor detects the blood glucose of the tissue fluid to generate and transmit the measured data to the controlling chip. The controlling chip can generate monitoring information by calculating the measured data.

Abstract: A lung-sound signal processing method, device and computer-readable storage medium. The lung-sound processing method includes: obtaining a lung sound signal; decomposing the lung sound signal, to obtain a crackle-sound component and a respiration-sound component; obtaining an inspiratory-phase period based on the respiration-sound component; extracting a crackle-sound signal located in the inspiratory-phase period from the crackle-sound component; and obtaining at least one feature parameter according to the crackle-sound signal.

Abstract: A wearable blood pressure measuring device includes a strap structure, a micro gas pump and a pressure sensor. The strap structure is adapted to be worn by a user and has an outer surface and an inner surface. The micro gas pump is disposed on the strap structure. The pressure sensor is combined with the micro gas pump through an elastic medium, disposed on the inner surface of the strap structure and in contact with skin of the user for monitoring blood pressure. The micro gas pump is operated to drive gas, wherein the gas is transported into the elastic medium to inflate the elastic medium with the gas. The expanded elastic medium pushes the pressure sensor to press against the skin of the user for facilitating measurement of a blood pressure of a target artery by a flattening and scanning operation.

Abstract: Systems and methods for processing sensor data are provided. In some embodiments, systems and methods are provided for calibration of a continuous analyte sensor. In some embodiments, systems and methods are provided for classification of a level of noise on a sensor signal. In some embodiments, systems and methods are provided for determining a rate of change for analyte concentration based on a continuous sensor signal. In some embodiments, systems and methods for alerting or alarming a patient based on prediction of glucose concentration are provided.

Abstract: A sensing element comprises a transistor having a gate electrode, a source electrode, a gate electrode and a semiconductor nanostructure connecting between the source and the gate electrodes. The semiconductor nanostructure is modified by a functional moiety covalently attached thereto. A voltage source is connected to the gate electrode. A controller controls a gate voltage applied by the voltage source to the gate electrode such as to reverse a redox reaction occurring when the moiety contacts a redox reactive agent.

Abstract: Mattress assemblies and pillows are provided that include a flexible biosensor array provided on a layer of the mattress assembly for sensing an electrical conductivity associated with sweat emitted from an end user of the mattress assembly and producing an ionic concentration of at least one electrolyte; and a processor connected to the flexible biosensor array for interpreting the ionic concentration of the at least one electrolyte. Also disclosed are processes for monitoring and analyzing sweat from an end user of the mattress assemblies and pillows.

Abstract: A sweat sensing device includes a plurality of sweat collection pads communicating with a sensor. Each of the pads is activated by a timing circuit which allows one or more of the pads to be activated at a selected time and subsequent deactivated after a defined period of time. This allows for selective collection of sweat from a plurality of pads over a prolonged period of time. An impedance measuring circuit can be employed to determine if one or more of the pads becomes disconnected, in order to avoid irritation. Further, the devices can use a common microfluidic device which both transports sweat activating substance, such as pilocarpine, to the surface of the skin and directs sweat away from the skin to a sensing device.

Abstract: The present invention provides novel approaches to determining the pH level of the upper GI tract, esophagus and stomach, as an indicator of proper GI function, nutrient absorption and as a means to gauge the overall health of a patient down to the cellular level. This may be determined, practically, in real time as a means of testing for and monitoring GI function without need for sedation or invasive procedures.

Abstract: A sensing device can be placed within the colon to study bowel function. The sensing device can include a flexible printed circuit board that includes at least one senor configured to record data related to bowel activity from a patient's colon; and a wireless transmitter configured to send the data from the patient's colon to an external device. The sensing device can also include at least one mucosal clip configured to fix the sensor board to a wall of the patient's colon for a measurement period. The flexible printed circuit board and/or the at least one mucosal clip are configured to be passed from the patient's colon after the measurement period through normal defecation.

Abstract: A method of non-invasive detection of an analyte includes generating a transmit signal having at least two different frequencies each of which is in a radio or microwave frequency range of the electromagnetic spectrum, and transmitting the transmit signal into a target containing at least one analyte of interest using at least one transmit antenna/element. At least one receive antenna/element that is decoupled from the at least one transmit antenna/element is used to detect a response resulting from transmitting the transmit signal by the at least one transmit antenna/element into the target containing the at least one analyte of interest. In one embodiment, the at least one transmit antenna/element can have a first geometry and the at least one receive antenna/element can have a second geometry that is geometrically different from the first geometry.

Abstract: Establishing an analyte database using analyte data that has been obtained using non-invasive analyte sensors, and using the analyte database to analyze data obtained using a non-invasive analyte sensor. Once the analyte database is established, the analyte database can be updated with new analyte data, and the analyte database can be used to analyze the new analyte data to derive information from the new analyte data. For example, in the case of a human target, the new analyte data together with the analyte database can be used to predict an actual or possible abnormal medical pathology of the human target.

Abstract: A cuff for monitoring physiological cycles has an exterior and interior surface and securing means. The cuff consists of a body having an upper curve, a lower curve and a height (CH) therebetween. A sensor adhered with a flexible protective overlay to the interior surface is in communication with a microprocessor storage means. The microprocessor storage means can be within the cuff or separate therefrom with communication between the sensor and the storage means being wireless or through a communication member. A locking tab, having a width less than the body, extends from one side of the body. A slot retaining area extends from the body on a side opposite the locking tab and contains a slot dimensioned to receive the locking tab. A pull tab is adjacent the slot retaining area opposite the body. The pull tab shares a base with the slot retaining area and has a top line and an end width less than the width of the body.

Abstract: The invention relates to an implantable sensor for detecting an electrical excitation of muscle cells, in particular cardiac muscle cells, wherein it is provided that the sensor comprises a dielectric component and a contact point for contacting muscle cells, which is connected to the dielectric component, so that an electric field in the dielectric component, and correspondingly a capacitance of the dielectric component, change with an electrical excitation of the muscle cells. The invention furthermore relates to a system comprising a sensor and an implant.

Abstract: Embodiments of the present disclosure include detecting a concurrent occurrence of a decrease in monitored analyte level and a corresponding decrease in monitored on-skin temperature, confirming a presence of an impending hypoglycemic condition, and asserting a notification corresponding to the confirmed impending hypoglycemic condition. Devices, methods, systems and kits incorporating the same are also provided.

Abstract: The present invention discloses a smart terminal and a smart wrist watch.

Abstract: A biological signal acquirer is attached to a subject and acquires a biological signal of the subject. A transmitter carried by the subject transmits the biological signal. A first communication port and a first camera are installed in a first location and connectable to a network. A second communication port and a second camera are installed in a second location and connectable to the network. A biological information acquiring device is connectable to the network and provided with a switcher. The switcher acquires, when communication establishment between the transmitter and the first communication port is detected, the biological signal through the first communication port as well as a first image taken by the first camera, and acquires, when communication establishment between the transmitter and the second communication port is detected, the biological signal through the second communication port as well as a second image taken by the second camera.

Abstract: A wearable monitoring system and associated method that is configured to (i) determine three dimensional displacement of the spine of a subject's chest wall with respect to the subject's spine, (ii) process the three dimensional anatomical data, (iii) determine at least one respiratory parameter associated with the monitored subject and value thereof as a function of the three dimensional anatomical data, and (iv) determine a respiratory disorder as a function of the determined respiratory parameter and value thereof.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous and subcutaneous measurement of glucose in a host.