Patents Examined by Eric J Messersmith
  • Patent number: 10602973
    Abstract: The present relates to a method, system and a device for non-invasive detection of urine flow from the bladder into the kidney(s). The method, system and device rely on measurements made at distinct time points and can be used to detect Vesicoureteral reflux. The method, system and device are designed to detect changes in urine volume in the ureter(s), bladder and/or kidney(s). The method and device measure conductivity changes by bioelectrical impedance or electrical impedance tomography technology.
    Type: Grant
    Filed: May 6, 2016
    Date of Patent: March 31, 2020
    Assignee: National University of Ireland, Galway
    Inventors: Sarah Loughney, Mark Bruzzi, Martin O'Halloran, Prem Puri, Ricardo Eleuterio
  • Patent number: 10595761
    Abstract: Disclosed is an adapter for use with a multi-port control valve that is used in a blood sampling, blood pressure monitoring system that includes a sampling site, a pressure transducer, and a reservoir. The multi-port control valve includes a partition and a rotatable valve member that rotates around to one of a reservoir port, a sampling site port, or a pressure transducer port to block fluid communication. The adapter comprises: a partition to define an input fluid path and an output fluid path, wherein the partition of the adapter mates with the partition of the multi-port control valve and a partition of the reservoir, in which, the partition in the adapter mates with the partition in the reservoir such that a fluid circuit is created from the multi-port control valve, through the adapter, and through the reservoir, and back to the multi-port control valve.
    Type: Grant
    Filed: May 25, 2018
    Date of Patent: March 24, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Andrew Nguyen Hoan, Mandana Farhadieh, Brian Patrick Murphy
  • Patent number: 10595900
    Abstract: The present embodiments relate generally to systems and methods for measuring an analyte in a host. More particularly, the present embodiments provide sensor applicators and methods of use with activation that implant the sensor, withdraw the insertion needle, engage the transmitter with the housing, and disengage the applicator from the housing. Systems and methods according to present principles allow for such steps to occur without significant loss of spring force, and without deleterious effects such as seal slingshotting.
    Type: Grant
    Filed: October 20, 2016
    Date of Patent: March 24, 2020
    Assignee: DexCom, Inc.
    Inventors: Ryan Everett Schoonmaker, Jennifer Blackwell, Christopher M. Davis, David DeRenzy, Eric Gobrecht, Jason Halac, Jonathan Hughes, Kathleen Suzanne Hurst, Randall Scott Koplin, Phong Lieu, Kyle Neuser, Todd Andrew Newhouse, Jack Pryor, Peter C. Simpson, Maria Noel Brown Wells, Justen Deering England, Stefanie Lynn Mah, Leonard Darius Barbod, Jillian K. Allen, Michael J. Estes, Philip Thomas Pupa, Timothy Joseph Goldsmith, Kyle Tinnell Keller
  • Patent number: 10575776
    Abstract: The invention includes a system and method for predicting the performance of production animals by analysis of heart and lung sounds to determine likelihoods the animals will develop BRD or other diseases or ailments. Vital signs of animals are recorded during an adrenergic sympathetic “flight or fight” situation. A cardio-pulmonary rate ratio is determined for each animal by dividing a normalized adjusted heart rate value by a normalized adjusted respiratory value. From the ratios calculated for each animal in a group, a ratio range is established. Ratio values at a lower end of the ratio range indicate higher relative respiration rates and poor lung performance due to disease. Ratio values at an upper end of the range may indicate low cardiac output and an inability to tolerate rapid weight gain. Ratio values at either end of the range may indicate compromised cardio-pulmonary function.
    Type: Grant
    Filed: April 29, 2015
    Date of Patent: March 3, 2020
    Assignee: INTERVET INC.
    Inventor: Kurt Brattain
  • Patent number: 10561353
    Abstract: Enzymatic and non-enzymatic detectors and associated membrane apparatus, and methods of use, such as within a fully implantable sensor apparatus. In one embodiment, detector performance is controlled through selective use of membrane configurations and enzyme region shapes, which enable accurate detection of blood glucose level within the solid tissue of the living host for extended periods of time. Isolation between the host's tissue and the underlying enzymes and reaction byproducts used in the detectors is also advantageously maintained in one embodiment via use of a non-enzyme containing permeable membrane formed of e.g., a biocompatible crosslinked protein-based material. Control of response range and/or rate in some embodiments also permits customization of sensor elements. In one variant, heterogeneous detector elements are used to, e.g., accommodate a wider range of blood glucose concentration within the host.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: February 18, 2020
    Inventors: Joseph Lucisano, Bahman Javidi, Lev Kurbanyan, Joe Lin, Timothy Routh, Bradley Walker
  • Patent number: 10561363
    Abstract: The medication alert watch is a medical instrument that is adapted for use with a person. The medication alert watch is adapted to be worn on a wrist of the person. The medication alert watch comprises a control system, a cuff mechanism, a heart sensor, a power system, a housing, and a band. The control system monitors and operates the cuff mechanism. The control system monitors the heart sensor. The power system provides electrical power to the control system, the cuff mechanism, and the heart sensor. The control system, the cuff mechanism, the heart sensor, and the power system are located in the housing. The band attaches the wrist to the housing. The medication alert watch: 1) maintains and monitors a plurality of appointments and generates notifications regarding the appointment; 2) monitors the medical status of the person; and, 3) generates notifications regarding the medical status of the person.
    Type: Grant
    Filed: October 26, 2016
    Date of Patent: February 18, 2020
    Inventors: Islande Florissant, Edny Florissant
  • Patent number: 10548502
    Abstract: A diagnostic method includes applying a vibration at a selected frequency to a location within a brain of a living subject (32). Electrical signals resulting from the vibration are measured at multiple positions on a scalp of the subject. The measured electrical signals are processed in order to compute an electrical gain matrix between the location within the brain and the positions on the scalp. Electroencephalogram (EEG) signals are measured at the multiple positions on the scalp. The EEG signals are filtered using the gain matrix in order to identify brain electrical activity originating from the location.
    Type: Grant
    Filed: August 21, 2017
    Date of Patent: February 4, 2020
    Inventors: Alex Bronstein, Evgeny Tsizin-Goldman
  • Patent number: 10542939
    Abstract: Embodiments of the present disclosure describe a method of monitoring a patient comprising generating an accelerometer signal of a patient via a patient medical device and capturing and sampling the accelerometer signal at a sampling rate that utilizes non-regular timing intervals. Embodiments further describe a patient medical device comprising sensors for monitoring an accelerometer signal of a patient and circuitry for sampling the accelerometer signal at a sampling rate that utilizes non-regular timing intervals. Embodiments also describe a method of processing physiological signals comprising monitoring ECG signals and accelerometer signals of a patient via a patient medical device and capturing an ECG segment and sampling the accelerometer signal at a sampling rate that utilizes non-regular timing intervals.
    Type: Grant
    Filed: November 14, 2016
    Date of Patent: January 28, 2020
    Assignee: Medtronic Monitoring, Inc.
    Inventors: Rodolphe Katra, Matthew Edelman, Scott Williams, Niranjan Chakravarthy, Arthur Lai
  • Patent number: 10542887
    Abstract: Techniques for transmitting diagnostic information stored in an implantable medical device (IMD) based on patient hospitalization are described. For example, the IMD may transmit higher resolution diagnostic information to a clinician and/or an external device during a hospitalization period to aid the clinician in evaluating heart failure treatment and when discharge is proper. This higher resolution diagnostic information may include one or more patient metrics automatically generated and transmitted by the IMD at least once every two hours. During a post-hospitalization period, the IMD may transmit lower resolution diagnostic information to a clinician that indicates a risk level of re-hospitalization. The lower resolution diagnostic information may include the risk level and/or patient metrics once a day, for example. In this manner, the IMD transmitted diagnostic information may be tailored to the specific heart failure monitoring needed by the patient.
    Type: Grant
    Filed: March 30, 2012
    Date of Patent: January 28, 2020
    Assignee: Medtronic, Inc.
    Inventors: Shantanu Sarkar, Jodi L. Redemske, Eduardo N. Warman, Douglas A. Hettrick, Kevin T. Ousdigian
  • Patent number: 10537255
    Abstract: The disclosure includes an apparatus including an elongated assembly, at least a portion of which is sized, shaped, or otherwise configured to be inserted into a human body to measure a physiological parameter at an internal location within the body. The elongated assembly includes an elongated member having a first length and an outer surface, a coil disposed about at least a portion of the elongated member, the coil having a second length, and at least one stand-off member positioned between the outer surface of the elongated member and the coil, where the at least one member is configured to prevent the coil from contacting an optical fiber positioned between the elongated member and the coil.
    Type: Grant
    Filed: November 20, 2014
    Date of Patent: January 21, 2020
    Assignee: Phyzhon Health Inc.
    Inventors: Michael J. Eberle, Diana Margaret Tasker, Howard Neil Rourke, David J. Spamer
  • Patent number: 10524672
    Abstract: Various embodiments include methods and devices for measuring blood pressure. Various embodiments may include receiving, from one or more arterial measurement sensors, a pulse waveform representing arterial pressure as a function of time for each pulse of a series of blood pressure pulses. The series of blood pressure pulses may be correlated to arterial distension at a measurement location of the arterial measurement sensors on a subject's body. One or more elevations of the measurement location may be received from one or more elevation sensors. At least one pulse in the series of pulses may be identified that represents a transitional pulse based on one or more characteristics of the at least one pulse. A diastolic blood pressure may be determined based on the at least one identified transitional pulse and elevation measurements that correspond to the one identified pulse.
    Type: Grant
    Filed: June 21, 2016
    Date of Patent: January 7, 2020
    Inventors: David Boettcher Baek, Lars Lading
  • Patent number: 10524703
    Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.
    Type: Grant
    Filed: January 24, 2014
    Date of Patent: January 7, 2020
    Assignee: DexCom, Inc.
    Inventors: Mark Brister, Paul V. Neale, James R. Petisce, James Thrower, Sean Saint, John Nolting
  • Patent number: 10512404
    Abstract: The present application provides methods and devices for determining input information, and generally relates to the field of wearable devices. A method disclosed herein comprises: in response to a first part of a body of a user executing an action, acquiring target blood-flow information about the first part or a second part that corresponds to the first part; and determining input information according to the target blood-flow information and reference information. According to the methods and devices, the body of the user is used as an input interface, thus cause an interaction area to be increased, which helps to improve input efficiency and user experience.
    Type: Grant
    Filed: January 7, 2016
    Date of Patent: December 24, 2019
    Inventors: Yuanchun Shi, Yuntao Wang, Chun Yu, Lin Du
  • Patent number: 10499818
    Abstract: A method for monitoring autoregulation includes, using a processor, using a processor to execute one or more routines on a memory. The one or more routines include receiving one or more physiological signals from a patient, determining a correlation-based measure indicative of the patient's autoregulation based on the one or more physiological signals, and generating an autoregulation profile of the patient based on autoregulation index values of the correlation-based measure. The autoregulation profile includes the autoregulation index values sorted into bins corresponding to different blood pressure ranges. The one or more routines also include designating a blood pressure range encompassing one or more of the bins as a blood pressure safe zone indicative of intact regulation and providing a signal to a display to display the autoregulation profile and a first indicator of the blood pressure safe zone.
    Type: Grant
    Filed: October 18, 2016
    Date of Patent: December 10, 2019
    Assignee: Covidien LP
    Inventors: Paul Stanley Addison, James N. Watson, Dean Montgomery
  • Patent number: 10492722
    Abstract: An example method for detecting respiratory disturbances experienced by a subject can include receiving an airflow signal and at least one of an acoustic or vibration signal, where the airflow, acoustic, and/or vibration signals are associated with the subjects breathing. At least one feature can be extracted from the airflow signal and at least one feature can be extracted from at least one of the acoustic or vibration signal. Based on the extracted features, at least one respiratory disturbance can be detected. The respiratory disturbance can be flow limited breath or inspiratory flow limitation (“IFL”).
    Type: Grant
    Filed: March 10, 2015
    Date of Patent: December 3, 2019
    Assignee: ZST Holdings, Inc.
    Inventors: John Remmers, Zbigniew Ludwik Topor, Joshua Grosse, Seyed Abdolali Zareian Jahromi
  • Patent number: 10492733
    Abstract: An apparatus for determining information indicative of cardiac malfunctions and abnormalities includes a processing device (502) configured to detect amplitude variation from a signal indicative of cardiovascular motion, where the amplitude variation element variation of the amplitude of a wave pattern, e.g. the AO-peak, repeating on the heart-beat rate on the signal. The processing device is configured to determine, at least partly on the basis of the detected amplitude variation, an indicator of cardiac malfunction and abnormality.
    Type: Grant
    Filed: April 17, 2013
    Date of Patent: December 3, 2019
    Assignee: PRECORDIOR OY
    Inventors: Juhani Airaksinen, Tero Koivisto, Joona Marku, Ari Paasio, Mikko Pankaala, Kati Sairanen, Tuomas Valtonen, Peter Virta
  • Patent number: 10485459
    Abstract: A sensor insertion device includes a first elastic member; a second elastic member; an elastic energy variable mechanism configured to elastically deform the first elastic member and the second elastic member to achieve an energy accumulated state; a first holding mechanism configured to hold a position of the first elastic member in the energy accumulated state; and a second holding mechanism configured to hold a position of the second elastic member in the energy accumulated state for a period of time during which, after the release of the first elastic member from the first holding mechanism in the energy accumulated state, the needle member is moved to the insertion position by the first elastic energy.
    Type: Grant
    Filed: September 6, 2017
    Date of Patent: November 26, 2019
    Inventors: Eiji Arita, Takeshi Tsubouchi, Hideyuki Momoki
  • Patent number: 10478108
    Abstract: An analyte monitor includes a sensor, a sensor control unit, and a display unit. The sensor has, for example, a substrate, a recessed channel formed in the substrate, and conductive material disposed in the recessed channel to form a working electrode. The sensor control unit typically has a housing adapted for placement on skin and is adapted to receive a portion of an electrochemical sensor. The sensor control unit also includes two or more conductive contacts disposed on the housing and configured for coupling to two or more contact pads on the sensor. A transmitter is disposed in the housing and coupled to the plurality of conductive contacts for transmitting data obtained using the sensor. The display unit has a receiver for receiving data transmitted by the transmitter of the sensor control unit and a display coupled to the receiver for displaying an indication of a level of an analyte.
    Type: Grant
    Filed: February 5, 2016
    Date of Patent: November 19, 2019
    Assignee: Abbott Diabetes Care Inc.
    Inventors: Howard Wolpert, Adam Heller
  • Patent number: 10478101
    Abstract: A passive sensing continuous glucose monitoring system and method of use thereof. The system includes a passive antenna formed of biocompatible silicon carbide (SiC), modeled to a desired frequency, which is permanently implanted subcutaneously. The system further includes an external-to-the-body transmitting antenna to detect changes in the blood glucose level by sending a radio signal at the frequency of the implanted passive antenna into the body. This signal is received and reflected by the passive antenna, and the reflected signal is then received at an external-to-the-body receiving antenna. Changes in the glucose level lead to modifications in the signal and can be used to determine the blood glucose level externally.
    Type: Grant
    Filed: October 5, 2016
    Date of Patent: November 19, 2019
    Assignee: University of South Florida
    Inventors: Fabiola Araujo Cespedes, Stephen E. Saddow, Christopher Leroy Frewin, Erdem Topsakal
  • Patent number: 10456081
    Abstract: Example blood pressure apparatus using active materials and related methods are described herein. An example apparatus includes a band to be worn around a limb of a user, an active material carried by the band and a controller to: (1) apply an activation signal to the active material to constrict blood flow in the limb, and (2) reduce the activation signal to allow blood flow in the limb.
    Type: Grant
    Filed: September 30, 2016
    Date of Patent: October 29, 2019
    Inventors: Mark E. Sprenger, Paul J. Gwin, Aaron P. Anderson, Christian Amoah-Kusi