Abstract: Implantable medical devices include circuitry positioned adjacent to header-related structures, rather than having the header and related structures sitting atop the position of the circuitry within a device housing. A circuit board within the device housing may be positioned adjacently to a lead bore of the header. Feedthrough conductors may extend from the circuitry to conductors of the header while being positioned adjacently to the circuit board. Lead frame conductors may extend to the electrical connectors of the lead bores while also being adjacent to the upper portion of the circuitry. Device height may be reduced by having the circuitry be positioned adjacent to one or more of the various header-related structures.

Abstract: This disclosure is directed to techniques for identifying false detection of asystole in a cardiac electrogram that include determining whether at least one of a plurality of false asystole detection criteria are satisfied. In some examples, the plurality of false asystole detection criteria includes a first false asystole detection criterion including a reduced amplitude threshold for detecting cardiac depolarizations in the cardiac electrogram, and a second false asystole detection criterion for detecting decaying noise in the cardiac electrogram.

Abstract: A computer-implemented system includes a treatment apparatus manipulated by a patient while performing an exercise session and a patient interface that receives a virtual avatar. The patient interface presents the virtual avatar. The virtual avatar uses a virtual representation of the treatment apparatus to guide the patient through an exercise session. A server computing device provides the virtual avatar of the patient to the patient interface and receives a message pertaining to a trigger event. The message includes a severity level of the trigger event. The server computing device determines whether a severity level of the trigger event exceeds a threshold severity level, and responsive to determining the severity level of the trigger event exceeds the threshold severity level, replaces on the patient interface the presentation of the virtual avatar with a presentation of a multimedia feed from a computing device of the medical professional.

Abstract: A tool actuation connector includes a tool activation interface, a longitudinal lock interface and a rotation lock interface. The tool actuation connector includes a latching spring, an inner sleeve and an outer sleeve. The latching spring includes a plurality of spring hooks, for coupling with the tool activation interface. The inner sleeve is operable to longitudinally move relative to the latching spring. The inner sleeve couples the latching spring to the activation interface when the inner sleeve is located over the latching spring and releases the latching spring from the activation interface when the inner sleeve moves away from the latching spring toward the proximal direction. The outer sleeve is rotationally locked with the inner sleeve and is operable to longitudinally move relative to the inner sleeve. The outer sleeve is further operable to rotationally lock with the tool via the rotation lock interface.

Abstract: A cardiac pacing system having a pulse generator for generating therapeutic electric pulses, a lead electrically coupled with the pulse generator having an electrode, a first sensor configured to monitor a physiological characteristic of a patient, a second sensor configured to monitor a second physiological characteristic of a patient and a controller. The controller can determine a pacing vector based on variables including a signal received from the second sensor, and cause the pulse generator to deliver the therapeutic electrical pulses according to the determined pacing vector. The controller can also modify pacing characteristics based on variables including a signal received from the second sensor.

Abstract: A computer-implemented system may include a treatment device configured to be manipulated by a user while the user is performing a treatment plan and a patient interface comprising an output device configured to present telemedicine information associated with a telemedicine session. The computer-implemented system may also include a first computing device configured to: receive treatment data pertaining to the user while the user uses the treatment device to perform the treatment plan; write to an associated memory, for access by an artificial intelligence engine, the treatment data; receive, from the artificial intelligence engine, at least one prediction; identify a threshold corresponding to the at least one prediction; and, in response to a determination that the at least one prediction is outside of the range of the threshold, update the treatment data pertaining to the user to indicate the at least one prediction.

Abstract: Computer-implemented systems, computer-implemented methods, and tangible, non-transitory computer-readable media for detecting abnormal heart rhythms of a user performing treatment plan with an electromechanical machine. The system includes, in one embodiment, an electromechanical machine, one or more sensors, and one or more processing devices. The electromechanical machine is configured to be manipulated by a user while the user is performing a treatment plan. The one or more sensors are configured to determine one or more measurements associated with the user. The one or more processing devices are configured to receive, from the one or more sensors while the user performs the treatment plan, the one or more measurements associated with the user. The one or more processing devices also configured to determine, using one or more machine learning models, a probability that the one or more measurements indicate that the user satisfies a threshold for a condition associated with an abnormal heart rhythm.

Abstract: Methods, systems, and computer-readable mediums for generating, by an artificial intelligence engine, treatment plans for optimizing a user outcome. The method comprises receiving attribute data associated with a user. The attribute data comprises one or more symptoms associated with the user. The method also comprises, while the user uses a treatment apparatus to perform a first treatment plan for the user, receiving measurement data associated with the user. The method further comprises generating, by the artificial intelligence engine configured to use one or more machine learning models, a second treatment plan for the user. The generating is based on at least the attribute data associated with the user and the measurement data associated with the user. The second treatment plan comprises a description of one or more predicted disease states of the user. The method also comprises transmitting, to a computing device, the second treatment plan for the user.

Abstract: A computer-implemented system may include an electromechanical machine configured to be manipulated by a user while the user performs a treatment plan, an interface comprising a display configured to present information associated with the treatment plan, and a processing device configured to receive, from one or more data sources, information associated with the user, wherein the information comprises one or more risk factors associated with a cardiac condition or a cardiac outcome, generate, using one or more trained machine learning models, the treatment plan for the user, wherein the treatment plan is generated based on the information associated with the user, and the treatment plan comprises one or more exercises associated with managing the one or more risk factors in order to reduce a probability of a cardiac intervention for the user, and transmit the treatment plan to cause the electromechanical machine to implement the one or more exercises.

Abstract: The present invention relates to a system and methods for noninvasively providing therapy for movement disorder symptoms. The present invention provides such a therapy system which provides trans-cranial direct current stimulation (tDCS) in order to treat those symptoms and the disorders. The present invention further provides such tDCS therapy while the subject sleeps in order to minimize the time required and impact of the therapy on the subject's waking life. The system, methods, and devices of the present invention are intended to provide a low-dose electrical current, trans-cranially, to a specific area of the subject's brain while he or she sleeps in order to decrease the occurrence, severity, and duration of the symptoms of movement disorders. The present invention aims to reduce the amount of medication necessary, counteract the effects of medication wearing off during sleep, and to overall improve the quality of life of subjects suffering from movement disorders.

Abstract: Neural network based heart rhythm classifiers are described. The neural network is configured to receive an electrocardiogram segment and to output an indication of whether the electrocardiogram segment represents a heart rhythm that is suitable for treatment by a defibrillation shock. Preferably, the received electrocardiogram segment is not transformed or processed prior to its reception by the neural network and no features of the electrocardiogram are identified to the neural network. In some embodiments, the received electrocardiogram segment is the sole input to the neural network. In various embodiments, the neural network is configured to classify electrocardiogram segments obtained while CPR was being performed on the patient. Classifiers that output a characteristic of CPR are also described. Such outputs may include an indication of whether CPR was being performed while the ECG was being detected, compression depth, etc. The described classifiers are well suited for use in defibrillators.

Abstract: Systems and methods for treating a subject with a psychiatric disorder are provided in which a therapy session is conducted. In the therapy session, each respective expression image in a plurality of expression images is sequentially displayed. Each expression image is independently associated with an expression. The successive display of images is construed as a tiled series of expression image subsets, each consisting of N expression images. Upon completion of the display of each respective subset, the user is challenged as to whether the first and the last images in the respective subset exhibit the same emotion. A score is determined for the respective subset based on whether the subject learned to respond correctly. The number of images in each subset is adjusted to a new number based on these scores. A treatment regimen is prescribed to the subject for the psychiatric disorder based at least in part on the scores.

Abstract: A system, apparatus, and method using multiple complementary sensors for the monitoring and wireless communication of several respiration characteristics—that is badge-size, wearable on the outside of clothing, and non-invasive.

Abstract: A method for aesthetic soft tissue treatment includes placing at least one applicator in contact with the patient's body. The applicator has at least one electrode. Electrotherapy and radio frequency therapy are provided to the soft tissue, optionally with overlay or sequentially. A handheld applicator may be used, with the applicator moving during the therapy, which may provide muscle stimulation in the patient, or provide an analgesic effect during the treatment. A spacing object may be positioned between the skin of the patient and the applicator.

Abstract: Electrical impulses are received from a beating heart. The electrical impulses are converted to an ECG waveform. The ECG waveform is converted to a frequency domain waveform, which, in turn, is separated into two or more different frequency domain waveforms, which, in turn, are converted into a plurality of time domain cardiac electrophysiological subwaveforms and discontinuity points between these subwaveforms. The plurality of subwaveforms and discontinuity points are compared to a database of subwaveforms and discontinuity points for normal and abnormal patients or to a set of rules developed from the database. An ST segment and one or more ST subwaveforms within the ST segment are identified from the plurality of subwaveforms and discontinuity points based on the comparison. The ECG waveform with the one or more ST subwaveforms within the ST segment is displayed.

Abstract: Various embodiments of a hermetically-sealed package and a method of forming such package are disclosed. The package includes a housing that extends along a housing axis between a first end and a second end, where the housing includes first and second opaque portions and a transparent portion disposed between the first and second opaque portions. The first opaque portion is hermetically sealed to a first end of the transparent portion and the second opaque portion is hermetically sealed to a second end of the transparent portion. At least one of the first and second opaque portions is hermetically sealed to the transparent portion by a weld ring. The package further includes a power source disposed within the housing, and an inductive coil disposed at least partially within the transparent portion of the housing and electrically connected to the power source.

Abstract: A surgical system is disclosed. The surgical system includes a monopolar return pad and a surgical hub wirelessly coupled to the monopolar return pad. The surgical hub includes a control circuit configured to determined a presence and a position of a patient on the monopolar return pad according to data received from the monopolar return pad.

Abstract: The present invention generally relates to an image-guided laser irradiation device for targeted ablation, stimulation, molecular delivery and therapy. Specifically, the invention relates to application of the device in therapies needing precise and targeted removal of a sample, or delivery of impermeable molecules for therapeutic outcome. More specifically, the invention relates to the application of the device in the therapy of visual disorders.

Abstract: According to one aspect, an implantable medical device may include an anchor assembly configured to anchor the medical device to a body lumen. The implantable medical device may also include a capsule. The capsule may include a pH sensor. The pH sensor may be configured to measure a pH of contents within the body lumen. The capsule may also include a power source, a controller, and an impedance sensor. The impedance sensor may be configured to measure an impedance within the body lumen.

Abstract: A system for delivering electrical pulse stimulation to a subject includes a remote control device configured to at least intermittently transmit temporal pulse pattern programming and a stimulation device comprising a control interface, at least one electrode in electrical communication with the control interface, and an input device in at least intermittent communication with the remote control device to receive the temporal pulse pattern programming. The stimulation device is configured to deliver electrical pulse stimulation to a subject via the at least one electrode according to the temporal pulse pattern programming.