Patents Examined by Hugh Maupin
  • Patent number: 10998176
    Abstract: The present embodiment relates to an ion detector provided with a structure for suppressing degradation over time in an electron multiplication mechanism in a multi-mode ion detector. The ion detector includes a dynode unit, a first electron detection portion including a semiconductor detector having an electron multiplication function, a second electron detection portion including an electrode, and a gate part. The first and second electron detection portions are capable of ion detection at different multiplication factors. The gate part includes at least a final-stage dynode as a gate electrode, and controls switching between passage and interruption of secondary electrons which are directed toward the first electron detection portion by adjusting a set potential of the gate electrode.
    Type: Grant
    Filed: February 21, 2019
    Date of Patent: May 4, 2021
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventors: Hiroshi Kobayashi, Takeshi Endo, Hiroki Moriya, Toshinari Mochizuki
  • Patent number: 10994993
    Abstract: A method of forming an enhanced super-resolution image is provided. The method includes: preparing a substrate comprising a glass substrate, a metal layer on the glass substrate, and a biolayer on the metal layer; placing a biological specimen on the substrate, the biological specimen being in contact with the biolayer and being attached to the metal layer through the biolayer, in which the biological specimen is labeled by a plurality of spontaneous blinking elements therein; irradiating a light beam to the metal layer via the glass substrate; receiving fluorescence signals emitted from the spontaneous blinking elements within a time period; fitting a plurality of functions respectively to each of the fluorescence signals; pinpointing peak positions of the functions; and reconstructing the peak positions to derive the enhanced super-resolution image of an underlying structure of the biological specimen in proximity to the metal layer.
    Type: Grant
    Filed: August 22, 2019
    Date of Patent: May 4, 2021
    Assignee: National Central University
    Inventors: Fan-Ching Chien, Chun-Yu Lin
  • Patent number: 10996346
    Abstract: An ?-ray measuring device which is provided with: a box-shaped chamber that has a gas inlet and a gas outlet; a cathode film which is provided within the box-shaped chamber; a plurality of anode wires which are arranged parallel to each other at a distance from the cathode film, while being electrically connected to each other and having a diameter of from 1 ?m to 30 ?m (inclusive); and a plurality of cathode wires which are arranged parallel to each other at a distance from the anode wires, while being electrically connected to the cathode film and having a diameter of from 1 ?m to 30 ?m (inclusive).
    Type: Grant
    Filed: April 22, 2019
    Date of Patent: May 4, 2021
    Assignee: MITSUBISHI MATERIALS CORPORATION
    Inventors: Yoshinori Sawada, Ichiro Shiono
  • Patent number: 10996169
    Abstract: A camera system includes one or more spectral illuminators, a tunable optical filter, and a sensor array. Active spectral light emitted from the one or more spectral illuminators towards a scene is dynamically tuned to an illumination sub-band selected from a plurality of different illumination sub-bands. Sequentially for each of a plurality of fluorescing light sub-bands different than the selected illumination sub-band, the tunable optical filter is adjusted to block light from being transmitted from the scene to the sensor array in all but a tested fluorescing light sub-band from the plurality of different fluorescing light sub-bands, and the sensor array is addressed to acquire one or more image of the scene in the tested fluorescing light sub-band.
    Type: Grant
    Filed: February 27, 2019
    Date of Patent: May 4, 2021
    Assignee: Microsoft Technology Licensing, LLC
    Inventors: Sergio Ortiz Egea, Maria Esther Pace, Onur Can Akkaya, Michael Scott Fenton
  • Patent number: 10987079
    Abstract: A radiation imaging system includes a plurality of imaging apparatuses configured to generate images based on radiation emitted from radiation generating apparatuses configured to perform radiation irradiation and a control apparatus configured to communicate with the plurality of the imaging apparatuses. The control apparatus comprises: an obtainment unit configured to obtain imaging information from each of the plurality of imaging apparatuses, a selection unit configured to select one imaging apparatus from the plurality of imaging apparatuses based on the imaging information obtained by the obtainment unit, and an image obtainment unit configured to obtain an image from the imaging apparatus selected by the selection unit, and the control apparatus further comprises a setting unit configured to set an imaging apparatus from which imaging information is obtained by the obtainment unit.
    Type: Grant
    Filed: April 10, 2019
    Date of Patent: April 27, 2021
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Tomohiro Kawanishi, Yuichi Nishii, Hikaru Tanaka, Kenta Endoh
  • Patent number: 10989662
    Abstract: The present disclosure provides devices and methods enabling the analysis of biomolecules. In some embodiments, the biomolecules may be DNA, RNA, protein, peptide, small molecule, catalyst, precursor, nucleotide, antibodies, or other biomolecules of interest.
    Type: Grant
    Filed: March 28, 2019
    Date of Patent: April 27, 2021
    Assignee: Azure Biosystems, Inc.
    Inventors: Diping Che, Zhefu Zhang
  • Patent number: 10989820
    Abstract: Disclosed herein is a radiation detector, comprising: a radiation absorption layer comprising an electrode; a voltage comparator that compares a voltage of the electrode to a first threshold; a counter that registers a number of photons of radiation absorbed by the radiation absorption layer; a controller; and a voltmeter. The controller is configured to start a time delay from a time at which the voltage comparator determines that an absolute value of the voltage equals or exceeds an absolute value of the first threshold. The controller is configured to cause the voltmeter to measure the voltage upon expiration of the time delay. The controller is configured to determine the number of photons by dividing the voltage measured by the voltmeter by a voltage that a single photon would have caused on the electrode. The controller can cause the number registered by the counter to increase by the number of photons.
    Type: Grant
    Filed: November 9, 2018
    Date of Patent: April 27, 2021
    Assignee: SHENZHEN XPECTVISION TECHNOLOGY CO., LTD.
    Inventors: Peiyan Cao, Yurun Liu
  • Patent number: 10983055
    Abstract: A sample observation apparatus includes a light source unit, an illumination optical system, a detection optical system, a light detection element, and an image processing apparatus. The scanning unit relatively moves the light spot and the sample. An optical member is disposed. The illumination optical system and the detection optical system are disposed such that an image of a pupil of the illumination optical system is formed at a pupil position of the detection optical system. The image of the pupil of the illumination optical system is decentered relative to a pupil of the detection optical system due to refraction caused by the sample. The illumination optical system, the detection optical system, and the optical member are configured such that quantity of light passing through the pupil of the detection optical system changes by decentering.
    Type: Grant
    Filed: May 13, 2019
    Date of Patent: April 20, 2021
    Assignee: OLYMPUS CORPORATION
    Inventors: Yoshimasa Suzuki, Mayumi Odaira
  • Patent number: 10983323
    Abstract: A fluorescence observation device includes: a first intensity-modulating unit that intensity-modulates, at a frequency f1, pump light that excites fluorescence of an observed subject; a second intensity-modulating unit that intensity-modulates, at a frequency f2 different from the frequency f1, probe light that induces stimulated emission of the observed subject; a light-receiving unit that receives the fluorescence from the observed subject irradiated with the intensity-modulated pump light and probe light; and a sensing unit that senses a component with a frequency of i×f1±j×f2 (i and j are positive integers, at least one of which is equal to or larger than two) in a reception-light signal sensed at the light-receiving unit.
    Type: Grant
    Filed: April 25, 2019
    Date of Patent: April 20, 2021
    Assignee: NIKON CORPORATION
    Inventor: Fumihiro Dake
  • Patent number: 10983047
    Abstract: Imaging devices including dielectric metamaterial absorbers and related methods are disclosed. According to an aspect, an imaging device includes a support. The imaging device also includes multiple dielectric metamaterial absorbers attached to the support. Each absorber includes one or more dielectric resonators configured to generate and emit thermal heat upon receipt of electromagnetic energy.
    Type: Grant
    Filed: December 7, 2018
    Date of Patent: April 20, 2021
    Assignee: Duke University
    Inventors: Willie Padilla, Kebin Fan, Xinyu Liu, Jonathan Suen
  • Patent number: 10982999
    Abstract: A system and a method for measuring ultraviolet ray protection of a cosmetic material. In an embodiment, the system for measuring the ultraviolet ray protection of a cosmetic material includes: a light source for emitting light including ultraviolet bands; a transparent plate through which the lights emitted from the light source pass, and having one surface to which a cosmetic material to be tested is applied; a wavelength conversion film, which changes, to a predetermined size, the light, of an ultraviolet band, of the light having passed through the transparent plate and makes the same pass therethrough; and a photosensitive sheet, which accommodates the light having passed through the wavelength conversion film and has a photosensitive property for light of UVA and UVB bands among the ultraviolet bands.
    Type: Grant
    Filed: September 26, 2017
    Date of Patent: April 20, 2021
    Assignee: AMOREPACIFIC CORPORATION
    Inventors: Yu-Chul Jung, Hae-Kwang Lee
  • Patent number: 10976452
    Abstract: A radiation detector assembly is provided that includes a semiconductor detector, plural pixelated anodes, and at least one processor. The semiconductor detector has a surface. The plural pixelated anodes are configured to generate a primary signal responsive to reception of a photon by the pixelated anode and to generate at least one secondary signal responsive to an induced charge caused by reception of a photon by at least one surrounding anode. The at least one processor is configured to: acquire a primary signal from one of the anodes responsive to reception of a photon; acquire at least one secondary signal from at least one neighboring pixel of the one of the anodes, the at least one secondary signal defining a negative value; and determine an energy correction factor for the reception of the photon using the negative value of the at least one secondary signal.
    Type: Grant
    Filed: November 18, 2019
    Date of Patent: April 13, 2021
    Inventors: Arie Shahar, Roi Harpaz, Elhanan Blaut
  • Patent number: 10971541
    Abstract: Some embodiments include a method, comprising: attaching a carrier substrate to a side of at least one semiconductor substrate, the at least one semiconductor substrate including photodetectors on the side; thinning the at least one semiconductor substrate while the at least one semiconductor substrate is attached to the carrier substrate; attaching an optical substrate to the at least one semiconductor substrate while the at least one semiconductor substrate is attached to the carrier substrate; and removing the carrier substrate from the at least one semiconductor substrate.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: April 6, 2021
    Assignee: Varex Imaging Corporation
    Inventors: Rick E. Colbeth, Ivan P. Mollov
  • Patent number: 10969502
    Abstract: A positron or beta particle detector comprising a first radiation sensor made of a first material and having a first thickness between a first surface and a second surface; and a second radiation sensor made of a second material and having a second thickness between a first surface and a second surface, the second radiation sensor being arranged at a first distance from the first radiation sensor; wherein the first material and the first thickness are such that a positron or beta particle can traverse the first radiation sensor from first to second surface and hit the first surface of the second radiation sensor.
    Type: Grant
    Filed: March 20, 2017
    Date of Patent: April 6, 2021
    Assignee: MIRION TECHNOLOGIES (CANBERRA OLEN) NV
    Inventors: Olivier Roger Valère Vincent Evrard, Wilhelm Friedrich Mueller, Sofie Antonie Joanna Put
  • Patent number: 10966676
    Abstract: Disclosed herein is a computed tomography system, comprising: a table with a hole therein, wherein the table is configured to support a person lying face down thereon, with at least one of the person's breasts projecting through the hole; an X-ray source; an X-ray detector comprising a plurality of pixels; wherein the X-ray source is configured to rotate around the at least one of the person's breasts.
    Type: Grant
    Filed: August 2, 2019
    Date of Patent: April 6, 2021
    Assignee: SHENZHEN XPECTVISION TECHNOLOGY CO., LTD.
    Inventors: Peiyan Cao, Rui Ding
  • Patent number: 10962661
    Abstract: Methods and systems for detecting a three-dimensional position of a scintillation event converting a radiation into a light. For example, a system includes a crystal array including a plurality of crystal elements arranged at least along a first direction and a second direction, the plurality of crystal elements extending along a third direction between a first end and a second end, the plurality of crystal elements being configured to receive the radiation entered from the second end; wherein: the plurality of crystal elements is arranged into a plurality of crystal pairs; each of the plurality of crystal pairs optically coupled to one light bridge at the first end extending and bridging light along the first direction; each of the plurality of crystal pairs is optically coupled for the light in the second direction with at least a neighboring crystal pair only through two light tunnels.
    Type: Grant
    Filed: July 31, 2019
    Date of Patent: March 30, 2021
    Assignee: Shanghai United Imaging Intelligence Co., Ltd.
    Inventors: Hongdi Li, Shaohui An
  • Patent number: 10962662
    Abstract: A method and apparatus are provided for positron emission imaging to calibrate timing of a pixelated gamma detector using multi-channel events. The apparatus can include processing circuitry configured to obtain calibration data representing a time and a position at which gamma rays are detected at a plurality of detector elements, and determine which gamma-ray detections of the calibration data correspond to multi-channel detections in which energy of a respective gamma ray is shared and detected by two or more of the plurality of detector elements. Additionally, the processing circuitry can be configured to determine a timing calibration of the plurality of detector elements by optimizing an objective representing agreement between time data of the multi-channel detections in the calibration data and the timing calibration.
    Type: Grant
    Filed: December 6, 2018
    Date of Patent: March 30, 2021
    Assignee: CANON MEDICAL SYSTEMS CORPORATION
    Inventors: Yi Qiang, Xiaoli Li, Kent C. Burr
  • Patent number: 10955349
    Abstract: A fluorescence observation device for observing fluorescence from an observed subject including a negative switching fluorescent substance that undergoes a transition from a deactivated state to an activated state triggered by activation light, and is excited by pump light when in the activated state includes: a first intensity-modulating unit that intensity-modulates the activation light at a frequency f1; a second intensity-modulating unit that intensity-modulates probe light at a frequency f3 different from the frequency f1, the probe light inducing stimulated emission of the observed subject; a light-receiving unit that receives fluorescence from the observed subject irradiated with the pump light, and the intensity-modulated probe light and activation light; and a sensing unit that senses a component with a frequency of f1±f3 in a reception-light signal from the light-receiving unit.
    Type: Grant
    Filed: April 30, 2019
    Date of Patent: March 23, 2021
    Assignee: NIKON CORPORATION
    Inventor: Fumihiro Dake
  • Patent number: 10955582
    Abstract: A wellbore inspection apparatus and a corresponding method of operation are described. The wellbore inspection apparatus comprises a neutron generator that produces, by a fusion reaction, a neutron and a corresponding charged particle. An associated particle imaging (API) detector comprises a particle detector array that detects the corresponding charged particle. The particle detector array comprises a plurality of particle detector elements that facilitate determining a trajectory of the neutron based upon a detection, by a particular one of the plurality of particle detector elements, of the corresponding charged particle. A gamma-ray detector assembly comprises a set of gamma-ray detector elements, and a set of collimating structures, where adjacent pairs of the set of collimating structures define a gamma-ray path for a gamma-ray arising from an inelastic collision of the neutron.
    Type: Grant
    Filed: February 26, 2019
    Date of Patent: March 23, 2021
    Assignee: Starfire Industries LLC
    Inventors: Brian E. Jurczyk, Robert A. Stubbers, Darren A. Alman, Matthew D. Coventry
  • Patent number: 10948404
    Abstract: A spectral imaging system configured to obtain spectral measurements in a plurality of spectral regions is described herein. The spectral imaging system comprises at least one optical detecting unit having a spectral response corresponding to a plurality of absorption peaks of a target chemical species. In an embodiment, the optical detecting unit may comprise an optical detector array, and one or more optical filters configured to selectively pass light in a spectral range, wherein a convolution of the responsivity of the optical detector array and the transmission spectrum of the one or more optical filters has a first peak in mid-wave infrared spectral region between 3-4 microns corresponding to a first absorption peak of methane and a second peak in a long-wave infrared spectral region between 6-8 microns corresponding to a second absorption peak of methane.
    Type: Grant
    Filed: October 20, 2017
    Date of Patent: March 16, 2021
    Assignee: REBELLION PHOTONICS, INC.
    Inventors: Robert Timothy Kester, Ohad Israel Balila