Abstract: An implantable medical device, such as a sensor for monitoring a selected internally detectable physiological parameter of a patient, is attached to a fixation assembly that is deployable within the patient to position and orient the sensor to enable it to perform its function. The fixation assembly is formed having at least one flexible asymmetric connector where each fixation member includes a plurality of loops, wherein a first loop of the plurality of loops has a maximum pitch that is different from a maximum pitch of a second loop of the plurality of loops. The attachment of the housing and the fixation assembly includes providing a tubular member that is welded to the housing and crimped over a section of the fixation assembly.

Abstract: An examination diagnosis device includes a probe, a stress detector and a grip. The probe has an elongated portion and a tip portion, and the tip portion is provided to be bent at one end of the elongated portion. The stress detector is configured to be able to detect a force in an X direction, a force in a Y direction and a force in a Z direction applied to the tip portion of the probe. The tip portion of the probe may be bent in a plane parallel to the X direction and the Z direction. A user allows the tip portion of the probe to come into contact with a joint portion that is a subject of examination and diagnosis while gripping the grip.

Abstract: Techniques for determining a volume of exhaled CO2 as a function of time using side-stream capnography, including obtaining flow dynamics measurements of a subject from a flow sensor; obtaining CO2 concentration measurements of the subject from a side-stream CO2 monitor; determining a duration of time (?Tsl) for a sample of gas to flow from a reference point to the side-stream CO2 monitor; synchronizing in time the CO2 concentration measurement with the flow dynamics measurement, based on the determined ?Tsl; and determining a volume of CO2 exhaled as a function of time, based on the flow dynamics measurement and the synchronized CO2 concentration measurement.

Abstract: Highly-swellable polymeric films are provided. Aspects also include ingestible compositions that include the highly-swellable polymeric film and an ingestible component. Aspects further include methods of making and using the compositions.

Abstract: An apparatus for measuring bio-information in a non-invasive manner includes: a pulse wave sensor configured to measure a plurality of pulse wave signals having different wavelengths from an object; a contact pressure sensor configured to measure contact pressure of the object while the plurality of pulse wave signals are measured; and a processor configured to obtain an oscillometric waveform based on the contact pressure and the plurality of pulse wave signals having the different wavelengths, and obtain bio-information based on the oscillometric waveform.

Abstract: This disclosure relates to a glucose-sensing electrode including a nanoporous metal layer and a maltose-blocking layer formed over the nanoporous metal layer. The nanoporous metal layer is capable of oxidizing both glucose and maltose without an enzyme specific to glucose or maltose in the glucose-sensing electrode. The maltose-blocking layer has porosity that permits glucose to pass therethrough and inhibits maltose from passing therethrough toward the nanoporous metal layer.

Abstract: A method for a device detects periodic breathing in a patient. The method may include receiving a series of event intervals bounded by apnea or hypopnea events detected in respiration of the patient, and processing, upon closure of an event interval, the event interval to determine a character of the event interval, such as any of: probably a periodic breathing cycle; probably not a periodic breathing cycle; and uninformative. The method may further include determining whether to change a current periodic breathing state that indicates whether a periodic breathing episode is in progress, based on a history of event interval characters that is long compared to the typical length of a periodic breathing cycle real-time detection of periodic breathing.

Abstract: Disclosed are devices for determining an analyte concentration (e.g., glucose). The devices comprise a sensor configured to generate a signal associated with a concentration of an analyte and a sensing membrane located over the sensor. The sensing membrane comprises an enzyme layer, wherein the enzyme layer comprises an enzyme and a polymer comprising polyurethane and/or polyurea segments and one or more zwitterionic repeating units. The enzyme layer protects the enzyme and prevents it from leaching from the sensing membrane into a host or deactivating.

Abstract: Embodiments provide devices, systems and methods for measuring a gastric emptying (GE) parameter (GEP). Many embodiments provide a swallowable capsule having three electrodes one covered by a coating which remains in the stomach but is degraded in the small intestine (SI). The electrodes are coupled to circuitry such that when the capsule is in the stomach, current flow occurs between the first two electrodes generating a first signal and in the SI current flow occurs between the second and now uncovered third electrode generating a second signal. These two signals can be transmitted and analyzed externally or by an internal controller to determine a GEP e.g., GE time. The patient may wear an external device configured to receive and analyze the signals to determine GE time. Embodiments of the invention may be used to diagnose gastroparesis and provide patient's information on when to eat meals or administer insulin after eating.

Abstract: A method of accounting for the movement of the lungs during an endoscopic procedure such that a previously acquired image may be dynamically registered with a display showing the position of a locatable guide. After an initial image set is acquired, an area of interest is identified and the movement thereof due to breathing is mathematically modeled. Patient movement sensors are then used to provide information on the patient's breathing patterns. This information is entered into the mathematical model in order to update the registration between the image set and a display showing the position of the locatable guide.

Abstract: A blood pressure information calculating device includes an input unit to which a waveform based on a pulse wave of the subject and reference blood pressure information serving as a reference for calculating the blood pressure information on the basis of the waveform based on the pulse wave are input, a conversion unit that calculates a phase spectrum of a waveform based on the pulse wave by performing Fourier transformation on the waveform based on the pulse wave, a calculation unit that calculates a correction value using at least one of a phase of a main wave corresponding to a pulse of the subject and a phase of a second harmonic wave of the main wave on the basis of the phase spectrum, and a calculation unit that calculates an average blood pressure by correcting the reference blood pressure information using the correction value.

Abstract: A method and apparatus to determine body composition of a subject is disclosed. Physical characteristics of a subject and water in a pool is determined. A body of the subject is completely submerged in the pool of water such that a head of the subject is just below a surface of the water in the pool. The subject completely exhales air into an air measuring device as the body of the subject is submerged just below the surface of the water. The body composition is then determined and displayed based on the determined subject characteristics, water characteristics and the amount of air exhaled into the air measuring device.

Abstract: Disclosed is finger cuff that is connectable to a patient's finger to be used in measuring the patient's blood pressure by a blood pressure measurement system. The finger cuff may comprise a fixed shell and a bladder. The fixed shell may have a finger cavity, in which the finger cavity of the fixed shell may be placed around a patient's finger to surround a large portion of the patient's finger including the middle knuckle to reduce finger movement, and in particular, to reduce relative movement between the middle phalanx and the proximal phalanx. Further, the fixed shell includes a support member that extends away from the finger cavity to abut against the underside of the patient's hand to reduce bending of the finger relative to the hand.

Abstract: Measured values are obtained from multiple points of a target by thinning out and measuring or measuring and then thinning out. A calculator 102 of a reconstructing device 101 calculates a variance/covariance matrix of the multiple points from calibration values measured at different points at the same time among the measured values. A corrector 103 obtains corrected values by interpolating unmeasured values for times when the measured values are absent at each of the multiple points. Here, the corrector 103 obtains the corrected values so that a variance/covariance matrix of the multiple points that should be calculated from the corrected values matches or approximates to the variance/covariance matrix calculated from the calibration values.

Abstract: A blood flow disorder detection device includes: a sensor sheet including a flexible substrate and a plurality of sensors provided on the flexible substrate; and an analyzer that analyzes outputs of the plurality of sensors. The plurality of sensors measure different types of blood flow information of a living tissue, the blood flow information being obtained by attaching the sensor sheet to the living tissue. The analyzer detects a blood flow disorder in the living tissue by analyzing the different types of blood flow information from the plurality of sensors.

Abstract: A medical instrument having an aspiration and/or injection needle and handle device. The handle device provides audible and/or tactile feedback during the application of activation forces, thus enabling the user to determine where the distal end of the aspiration and/or injection needle is relative to a sheath. More than two grooves are present on a shaft of an activation handle of the handle device. An O-ring resides within a handle portion of the handle device. The O-ring seats and unseats within the grooves based on the amount of applied force.

Abstract: Systems for monitoring left atrial pressure using implantable cardiac monitoring devices and, more specifically, to a left atrial pressure sensor implanted through a septal wall are presented herein.

Abstract: The invention relates to a method of testing an infant, comprising the following steps: displaying a target on a screen; detecting contact made by the infant with the screen inside and/or outside the target; calculating a success parameter on the basis of the contact detected; and recording the calculated success parameter in a memory.

Abstract: The invention is a method for calibrating an intravascular pressure sensor at the point of use. By using data from a secondary pressure measurement device, e.g., an automated aortic pressure monitor, the pressure sensor can be easily calibrated over a range of temperatures and pressures relevant to the patient. Accordingly, an intravascular pressure sensor can be calibrated without undergoing a factory calibration. Additionally, in the event that the calibration is lost, the sensor can be recalibrated.

Abstract: A patient monitoring system includes an electroencephalography (EEG) monitor and an EEG sensor array. The EEG sensor array includes a plurality of electrodes configured to acquire EEG signals from a patient. The EEG monitor may be configured to calculate one or more depth of anesthesia indices for the patient based on received EEG signals from the EEG sensor array. Additionally, the EEG monitor may be configured to generate and display a topographic color map of the calculated depth of anesthesia indices.