Abstract: A pulse measuring device of the disclosure includes a housing, a light-emitting device, a light-receiving device, and a light guide body having a first end surface facing the light-emitting device, a second end surface facing the first end surface and facing the light-receiving device, one or a plurality of first side surfaces covered by the housing, and one or a plurality of second side surfaces exposed from the housing.

Abstract: Introduced here is technology to monitor moisture levels in a hygiene product, such as tampons, pads, menstrual cups, child diapers, adult diapers etc. According to one embodiment, a moisture sensor is inserted inside a feminine hygiene product. The moisture sensor is connected to a wearable device that gathers the moisture data and sends the data to a mobile device, such as a cell phone. The cell phone generates notifications to the user, such as percentage saturation of the feminine hygiene product, message to change the feminine hygiene product, expected start and end dates of the next menstrual cycle, etc. According to another embodiment, the moisture sensor can be inserted in other hygiene products, such as child diapers or adult diapers, to measure the amount of urination, defecation, or other excretions, and to generate notifications to the user, the user's caretaker, or a third party.

Abstract: The invention relates to a respiratory flow sensor (11) comprising a flow tube (12) which has a flow channel (13) and tube connections for tubes at the free ends (15, 17) of the flow tube, a cover flap (32) which is arranged in the flow channel (13) and divides the flow channel (13) into a first flow channel section (18) and a second flow channel section (19), and comprising connections (22, 23) which open into the flow channel (13) on both sides of the cover flap (32) and which are used to decrease the pressure difference generated by the cover flap (32). A drainage device (41) which comprises drain grooves (42, 43) is provided in the flow channel (13), and the cover flap (32) has a hinge region which is formed by a first slot and a second H-shaped slot.

Abstract: A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the EIS-based diagnostics, fusion algorithms, and other processes based on measurement of EIS-based parameters.

Abstract: Electrical impedance myography (EIM) can be used for the assessment and diagnosis of muscular disorders. EIM includes applying an electrical signal to a region of tissue and measuring a resulting signal. A characteristic of the region of tissue is determined based on the measurement. Performing EIM at different frequencies and/or different angular orientations with respect to a muscle can aid in the assessment and diagnosis. Devices are described that facilitate assessment and diagnosis using EIM.

Abstract: Devices, systems, and methods to determine fractional flow reserve. At least one method for determining fractional flow reserve of the present disclosure comprises the steps positioning a device comprising at least two sensors within a luminal organ at or near a stenosis, wherein the at least two sensors are separated a predetermined distance from one another, operating the device to determine flow velocity of a second fluid introduced into me luminal organ to temporarily displace a first fluid present within the luminal organ, and determining fractional flow reserve at or near the stenosis based upon the flow velocity, a mean aortic pressure within the luminal organ, and at least one cross-sectional area at or near the stenosis. Devices and systems useful for performing such exemplary methods are also disclosed herein.

Abstract: A system and method for automatically analyzing heart failure in a patient, including collecting physiological data from a patient using at least a first sensor and a second sensor to collect two or more sensor measurements, and calculating a first composite value based on at least a first sensor measurement wherein the first composite value is an indication of a likelihood that the patient's heart failure status has changed. If the first composite value is outside of a first specified range, then a second composite value is calculated based on at least a second sensor measurement, wherein the second composite value is an indication of a likelihood that the patient's heart failure status has changed. If the second composite value is outside of a second specified range, then an alert of change in heart failure status is generated.

Abstract: A spirometer includes a housing, a mouthpiece coupled to the housing, and a measurement unit. The measurement unit is configured to receive air expelled by a user, and generate an electrical quantity corresponding to a peak expiratory flow or a forced expiratory volume based on the expelled air. The spirometer also includes a processing module supported by the housing, and configured to receive the electrical quantity from the measurement unit, a display coupled to the measurement unit to display an indication of the peak expiratory flow or the forced expiratory volume, and an energy harvester. The energy harvester is coupled to the measurement unit and the processing module, and is configured to receive energy from one of a group consisting of the measurement unit and an energy sensor, store the received energy in an energy storage device, and transfer the energy to the processing module.

Abstract: Methods, devices, and systems are disclosed for producing cognitive and/or sensory profiles. In one aspect, a method to provide a cognitive or sensory assessment of a subject includes selecting a profile category from among a cognitive performance profile, a sensory performance profile, and a cognitive and sensory performance profile, presenting a sequence of stimuli to a subject, the sequence of stimuli based on the selected profile category, acquiring physiological signals of the subject before, during, and after the presenting the sequence of stimuli to produce physiological data, and processing the physiological data to generate an information set including one or more quantitative values associated with the selected profile category.

Abstract: A respiratory monitoring apparatus comprises at least one motion sensor and a processing device. The at least one motion sensor senses an angular motion of a measured part capable of indicating a respiratory motion, and outputs an angular velocity vector of the measured part; the processing device, connected to the motion sensor, extracts a respiratory angular velocity from the angular velocity vector, and acquires a respiratory wave according to the respiratory angular velocity.

Abstract: An oximetry sensor assembly connector, and a method for making the same, is provided that includes a flexible circuit and a stiffener panel. The flexible circuit has a plurality of layers including at least one electrical trace layer and at least one electromagnetic interference (EMI) shield layer. The stiffener panel has a first side surface and a second side surface, which second side surface is opposite the first side surface. The flexible circuit includes a first segment and a second segment, and one or more of the plurality of layers are disposed within the first segment and the second segment. The flexible circuit is folded such that the first segment is contiguous with the first side surface of the stiffener panel, and the second segment is contiguous with the second side surface of the stiffener panel.

Abstract: Embodiments include a system for displays cardiovascular information for a patient. The system may include at least one computer system configured to receive patient-specific data regarding a geometry of the patient's heart and create a model representing at least a portion of the patient's heart based on the patient-specific data. The computer system may determine at least one value of the blood flow characteristic within the patient's heart based on the model. The computer system may also display a report comprising a representation of at least one artery corresponding to at least a portion the model, and display one or more indicators of the value of the blood flow characteristic on a corresponding portion of the at least one artery.

Abstract: Disclosed is a wearable electronic device including a body portion wearable on a human body, a circuit portion mounted on the body portion, and a sensor portion contacting the human body to measure a bio signal, wherein the sensor portion is detachably coupled to the body portion.

Abstract: Various methods and systems are provided for cerebral diagnosis. In one example, among others, a method includes obtaining EEG signals from sensors positioned on a subject; conditioning data from the EEG signals to remove artifacts; generating a cerebral network model based at least in part upon the conditioned data; determining network features based upon the cerebral network model; and determining a cerebral condition of the subject based at least in part upon the network features. In another example, a method includes determining a recording condition of a positioned EEG sensor and providing an indication of an unacceptable recording condition of the EEG sensor. In another example, a system includes an EEG recording module to acquire signals; a signal conditioning module to condition signal data; a signal analysis module to determine signal features and cerebral network features; and a condition classification module to determine a cerebral condition of the subject.

Abstract: A biosensor device for the real-time detection of a target analyte includes a receptor component operatively connected to a transducer component which is adapted to interpret and transmit a detectable signal. The receptor component includes a sensing element capable of detecting and binding to at least one target analyte, and a self-assembled monolayer (SAM) layer. The SAM layer is positioned between and in contact with the sensing element and an electrode such that the sensing element, in the presence of the target analyte, causes a detectable signal capable of being transmitted to the electrode. The transducer component includes the electrode and microprocessor configured to screen noise and to pick up impedance change at a very low frequency range.

Abstract: Intravascular diagnosis apparatus and methods are disclosed. In one aspect of the disclosed technology, a monitoring guidewire includes a core wire having or made of one or more of MP35N, L605, Elgiloy, and an alloy of nickel, cobalt, molybdenum and chromium, a sensor disposed in a distal region of the core wire, and a housing substantially coextensive with the core wire and surrounding the core wire, the housing being more flexible than the core wire for at least the distal portion of the housing.

Abstract: System and methods for detecting precursors of VAP in a patient being ventilated. An exemplary method comprises obtaining a baseline value for a content of a particular VOC in tVOCs in exhaled breath of the patient being ventilated, trending changes of values of the content of the particular VOC in the tVOCs measured at various points of time after ventilation compared to the baseline value, determining whether the patient has potentially infected VAP based at least in part on the trending, and in response to determining that the patient has potentially infected the VAP, generating an alert.

Abstract: A blood glucose measurement apparatus includes: a control unit configured to determine a user's blood glucose level based on a concentration of body fluid secreted from the user; and a biometric information acquisition unit configured to acquire biometric information indicating a status of a user's autonomic nervous system. The control unit is configured to correct the determined blood glucose level based on the biometric information.

Abstract: In some examples, a sensor holder device is described. The sensor holder device may include a rigid body, a set legs attached to the rigid body, a sensor guiding structure, a sensor retaining structure, and an electrical trace. The sensor retaining structure may be sized to accommodate a sensor wire. The electrical trace may extend proximate the sensor retaining structure and along one of the legs.

Abstract: An arrangement (100) and a device (101) for determining pulse transit time comprise an accelerometer (102) and a pulse wave sensor (103) for sensing a pulse wave. The accelerometer (102) determines a cardiac systole, and the pulse wave sensor (103) determines the pulse wave induced by said cardiac systole ejection. A first trigger signal is determined at the moment of said determined cardiac systole, and a second trigger signal at the moment of said determined pulse wave. The pulse transit time is then determined as a time difference between said first and second trigger signals.