Patents Examined by Kara Geisel
  • Patent number: 8947653
    Abstract: A method for detecting a coating on a bottle includes directing light at a first point of incidence on the bottle and detecting a first intensity of reflected light from the first point of incidence on the bottle. Further, light is directed at a second point of incidence on the bottle and a second intensity of reflected light from the second point of incidence on the bottle is detected. The first intensity is compared to the second intensity to determine whether the coating on the bottle has been uniformly deposited.
    Type: Grant
    Filed: May 14, 2012
    Date of Patent: February 3, 2015
    Assignee: Nano Scale Surface Systems, Inc.
    Inventors: John Thomas Felts, Christopher John Felts
  • Patent number: 8922777
    Abstract: A method of calibrating an optical density sensor comprising calculating a first pigment solid density value of an ink solution using a current first electrical output signal value from a photodetector, a current second electrical output signal value from a photodetector, and a current lens gap value, calculating a second pigment solid density value of the ink solution using a previously measured first electrical output signal value, a previously measured second electrical output signal value, and a previously measured lens gap value, comparing the current first electrical output signal value, the current second electrical output signal value, and the current lens gap value with the previously measured first electrical output signal value, the previously measure second electrical output signal value, and the previously measured lens gap value, and comparing the first pigment solid density value with the second pigment solid density value.
    Type: Grant
    Filed: June 14, 2011
    Date of Patent: December 30, 2014
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Zvi Shemer, Ziv Gilan, Niv Shemtov, Shlomo Harush, Natty Levy, Amit Porat
  • Patent number: 7405824
    Abstract: A light measuring device is designed, so that excitation light, emitted by a light source, is guided through an excitation light optical fiber to irradiate a sample, and that fluorescence discharged by the sample is guided to an optical detection system through a receiving light optical fiber. A coupling lens is arranged ahead of the excitation light optical fiber and ahead of the receiving light optical fiber on the sample side. A sample container for retaining a sample is so designed that a lens portion, for collecting excitation light and fluorescence, is integrally formed with the cylindrical bottom. According to this arrangement, excitation light is changed to parallel light or converged light by the coupling lens, and is collected at the sample by the lens portion integrally formed with the bottom of the sample container.
    Type: Grant
    Filed: November 9, 2006
    Date of Patent: July 29, 2008
    Assignee: Nippon Sheet Glass Company, Limited
    Inventors: Naoko Hikichi, Kenichi Nakama
  • Patent number: 7400399
    Abstract: Methods of detecting one or more parameters of a medium are disclosed. The methods include providing a waveguide grating device, contacting the waveguide grating with a medium, propagating a signal having at least one signal attribute through the waveguide, and comparing the modified signal attribute to a known signal attribute to detect a parameter of the medium.
    Type: Grant
    Filed: December 16, 2005
    Date of Patent: July 15, 2008
    Assignee: Board of Regents, The University of Texas System
    Inventors: Debra D. Wawro, Sorin Tibuleac, Robert Magnusson
  • Patent number: 7400395
    Abstract: The disclosed methods and apparatus concern Raman spectroscopy using metal coated nanocrystalline porous silicon substrates. Porous silicon substrates may be formed by anodic etching in dilute hydrofluoric acid. A thin coating of a Raman active metal, such as gold or silver, may be coated onto the porous silicon by cathodic electromigration or any known technique. In certain alternatives, the metal coated porous silicon substrate comprises a plasma-oxidized, dip and decomposed porous silicon substrate. The metal-coated substrate provides an extensive, metal rich environment for SERS, SERRS, hyper-Raman and/or CARS Raman spectroscopy. In certain alternatives, metal nanoparticles may be added to the metal-coated substrate to further enhance the Raman signals. Raman spectroscopy may be used to detect, identify and/or quantify a wide variety of analytes, using the disclosed methods and apparatus.
    Type: Grant
    Filed: October 31, 2005
    Date of Patent: July 15, 2008
    Assignee: Intel Corporation
    Inventors: Selena Chan, Andrew A. Berlin, Sunghoon Kwon, Narayanan Sundararajan, Mineo Yamakawa
  • Patent number: 7355710
    Abstract: An optical system for exciting and measuring fluorescence of samples has a first laser; a deflection element; a mirror; and an optic fixed in relation to one another. A unit is linearly movable back and forth along the optical axis and is mechanically connected to an oscillating linear drive. The optic acts as a collimator and the mirror acts to deflect the collimated light diametrically opposite to the bundled light of the laser. A table for receiving sample holders for samples; an optical arrangement for imaging a second focal point; an aperture plate in the second focal point; a first spectral filter; and a first detector are parts of the optical system and a focusing beam of the light emitted by the laser and is deflected by the deflection element toward the mirror.
    Type: Grant
    Filed: November 14, 2006
    Date of Patent: April 8, 2008
    Assignee: Tecan Trading AG
    Inventors: Andreas Gfrörer, Josef Atzler
  • Patent number: 7349093
    Abstract: On a substrate 41 holding a sample to be detected, a dielectric multilayer 42 is disposed which reflects excitation light e1 supplied from above the substrate 41 and transmits fluorescence f1 emitted from the sample, and the excitation light e1 is reflected at the dielectric multilayer 42 while the transmitted fluorescence f1 is detected by a light receiving unit 44, thereby providing a fluorescence measurement apparatus which can resolve a problem of reduction in detection sensitivity due to autofluorescence from the substrate or leakage of the excitation light from a light receiving filter, and which can detect the sample with high sensitivity.
    Type: Grant
    Filed: February 3, 2006
    Date of Patent: March 25, 2008
    Assignee: Matsushita Electric Industrial Co., Ltd.
    Inventors: Jimpei Tabata, Satoshi Miyagawa
  • Patent number: 7339656
    Abstract: An apparatus for measuring plasma electron density precisely measures electron density in plasma even under a low electron density condition or high pressure condition. This plasma electron density measuring apparatus includes a vector network analyzer in a measuring unit, which measures a complex reflection coefficient and determines a frequency characteristic of an imaginary part of the coefficient. A resonance frequency at a point where the imaginary part of the complex reflection coefficient is zero-crossed is read and the electron density is calculated based on the resonance frequency by a measurement control unit.
    Type: Grant
    Filed: April 26, 2004
    Date of Patent: March 4, 2008
    Assignee: Tokyo Electron Limited
    Inventors: Naoki Matsumoto, Yohei Yamazawa, Chishio Koshimizu, Tatsuo Matsudo, Sumie Segawa
  • Patent number: 7339666
    Abstract: Structures for amplifying light include a resonant cavity in which an analyte may be positioned. The structures for amplifying light may be used to amplify the incident light employed in surface enhanced Raman spectroscopy (SERS). SERS systems employing the structures for amplifying light of the present invention and methods of performing SERS are also disclosed.
    Type: Grant
    Filed: September 14, 2004
    Date of Patent: March 4, 2008
    Assignee: Hewlett-Packard Development Company, L.P.
    Inventors: Shih-Yuan Wang, Zhiyong Li, M. Saif Islam
  • Patent number: 7317532
    Abstract: An assay result reading device for reading the result of an assay performed using a liquid transport carrier may include at least one light source capable of emitting light incident upon at least one of two or more spatially separated zones of the carrier, a photodetector so positioned as to be capable of detecting light emanating from each of the two said zones and generating signals representing the presence or absence of a fluid sample in the respective zone, and a computation circuit. The computation circuit may be responsive to the signals to calculate a flow rate for a fluid flowing along the carrier, compare the calculated flow rate to upper and lower limits, and reject the assay result if the calculated flow rate is outside the upper and lower limits.
    Type: Grant
    Filed: December 19, 2003
    Date of Patent: January 8, 2008
    Assignee: Inverness Medical Switzerland GmbH
    Inventors: Stephen P. Sharrock, Andrew P. Phelan
  • Patent number: 7315378
    Abstract: Disclosed, in one aspect, is an assay result reading device for reading the result of an assay performed using a test strip, the device comprising: a light source or sources, said light source/s emitting light incident upon at least two, spatially separated zones of the test strip; and a photodetector which detects light emanating from each of the two said zones; in a further aspect is disclosed an assay result reading device for reading the result of an assay performed using a test strip, the device comprising: at least one light source incident upon a zone of the test strip; and at least two photodetectors both of which are able to detect some of the light emanating from the zone of the test strip illuminated by the light source.
    Type: Grant
    Filed: April 1, 2004
    Date of Patent: January 1, 2008
    Assignee: Inverness Medical Switzerland GmbH
    Inventors: Andrew Peter Phelan, Stephen Paul Sharrock
  • Patent number: 7312867
    Abstract: Disclosed is a device for detecting at least one luminescent substance, comprising a radiation source for emitting excitation radiation to the at least one luminescent substance. The excitation radiation is provided with at least one excitation wavelength at which the luminescent substance is excited so as to emit luminescent radiation. At least one radiation receiver is provided, which detects the luminescent radiation and is configured regarding the spectral sensitivity thereof in such a way that said radiation receiver is insensitive to the radiation emitted by the radiation source. The luminescent substance is located inside a measuring chamber that is essentially impermeable to the luminescent radiation and comprises at least one wall area which is transparent to the excitation radiation emitted by the radiation source.
    Type: Grant
    Filed: September 12, 2003
    Date of Patent: December 25, 2007
    Assignee: Micronas Holding GmbH
    Inventors: Holger Klapproth, Mirko Lehmann
  • Patent number: 7310142
    Abstract: Photons emitted from a sample responsive to being excited by laser pulses are directed through a prism onto a photomultiplier tube having several spaced-apart anodes. The prism alters the path of each photon as a function of its wavelength so that the wavelength determines the anode to which the photon is directed. Taps of first and second delay lines that are coupled to respective alternating anodes. When an anode receives the photon, it generates a pulse that propagates through the delay line in opposite directions from its associated tap. A timer determines first and second times from the laser pulse to the pulse reaching the first and second ends of the delay line. The difference between the first and second times corresponds to the wavelength of the emitted photon and the sum of the first and second times corresponds to the emission delay of the emitted photon.
    Type: Grant
    Filed: August 22, 2005
    Date of Patent: December 18, 2007
    Assignee: Sandia National Laboratories
    Inventors: Carl C. Hayden, David W. Chandler, A. Khai Luong
  • Patent number: 7304724
    Abstract: A device and method for accurately performing quantitative diffuse optical spectroscopy on a sample includes a light source and a source optical fiber that is optically coupled to the light source. A diffuser material is interposed between the source optical fiber and the sample, the diffuser material comprising a high scattering, low absorption material. The diffuser material effectively increases the photon path length from the light source to the sample, which limits the depth of interrogation to superficial volumes despite the penetrating nature of the radiation typically used. A detector optical fiber is provided adjacent to or laterally disposed from the source optical fiber. The detector optical fiber is coupled to a detector which detects photons collected in the detector optical fiber. The detector optical fiber and the source optical fiber may be separated by a distance of less than 5 mm while still permitting the diffusion approximation to remain valid.
    Type: Grant
    Filed: April 12, 2005
    Date of Patent: December 4, 2007
    Assignee: The Regents of the University of California
    Inventors: Anthony J. Durkin, Sheng-Hao Tseng
  • Patent number: 7304739
    Abstract: A method to change the color of hair. The method includes measuring an initial reflectance spectrum of a sample of the hair and analyzing a contribution of a plurality of natural hair factors to the initial reflectance spectrum. The method also includes calculating a hair treatment based on another reflectance spectrum. A system to measure a reflectance spectrum of a sample includes an integrating sphere having a sampling port and an inner surface and a window disposed near the sampling port. The window is configured for being placed in close contact with the sample. The system also includes a light source configured to project light onto the sample via the window and a light detector configured to analyze light reflected from the inner surface to produce the reflectance spectrum of the sample.
    Type: Grant
    Filed: June 25, 2003
    Date of Patent: December 4, 2007
    Assignee: SeeThrough Ltd.
    Inventors: Israel Grossinger, Avigdor Schertz, Michel Mercier, Eli Benni
  • Patent number: 7301628
    Abstract: Method and apparatus for detecting biomolecular interactions. The use of labels is not required and the methods may be performed in a high-throughput manner. An apparatus for detecting biochemical interactions occurring on the surface of a biosensor includes a light source. A first optical fiber is coupled to the light source and illuminates the biosensor. A second optical fiber detects a wavelength reflected from the biosensor. A spectrometer determines spectra of a reflected signal from the biosensor.
    Type: Grant
    Filed: April 13, 2006
    Date of Patent: November 27, 2007
    Assignee: SRU Biosystems, Inc.
    Inventors: Brian T. Cunningham, Peter Y. Li, Frank DiFilippi
  • Patent number: 7301632
    Abstract: The invention describes a method to eliminate instrumental offset in measurement of optically active scattering and circular dichroism. The method uses the time-average measurement of the light that is systematically transformed by a series of optical devices. The optical devises perform the function of rotating linearly polarized light, interconverting left and right circular polarized light, converting circular polarized light to rotating linear polarized light and converting linear polarized light to alternating left and right circular polarized light.
    Type: Grant
    Filed: December 13, 2005
    Date of Patent: November 27, 2007
    Assignee: BioTools, Inc.
    Inventor: Werner Hug
  • Patent number: 7301613
    Abstract: A wavefront analysing device, of the Hartmann or Shack-Hartmann type, comprises in particular a set of sampling elements arranged in an analysis plane, and forming as many micro-lenses for sampling the incident wavefront, and a diffraction plane wherein are analysed the Airy discs of the different micro-lenses illuminated by the incident wavefront. The shape of each micro-lens is such that the associated diffraction figure has in the diffraction plane one or several preferential axe(s), and the microlenses are oriented in the analysis plane such that the preferential axe(s) of the diffraction figure of a micro-lens are offset relative to the preferential axes of the diffraction figures of neighbouring micro-lenses, thereby enabling to limit the overlapping of the diffraction figures.
    Type: Grant
    Filed: July 12, 2002
    Date of Patent: November 27, 2007
    Assignee: Imagine Optic
    Inventors: Xavier Jean-François Levecq, Fabrice Harms
  • Patent number: 7301627
    Abstract: A method for monitoring a process output with a highly abridged spectrophotometer. The method includes securing spectral data for each spectral primary used in a process, measuring spectral data with a highly abridged spectrophotometer for a sample produced by the process, determining an estimated weight for each spectral primary in the sample, and computing spectral data representative of the sample based on the secured spectral data and the determined estimated weight for each spectral primary in the sample.
    Type: Grant
    Filed: April 4, 2006
    Date of Patent: November 27, 2007
    Assignee: X-Rite, Inc.
    Inventors: James L. Overbeck, Thomas Richardson
  • Patent number: 7298475
    Abstract: A method, suitable for stand off analysis of a sample (2), comprising: (i) using an excitation means (6) to vaporise the sample (2) thereby producing a vapour plume (10) of molecular species; and (ii) using an analytical means (12) to analyse molecular species within the vapour plume (10) wherein the analytical means (12) analyses the molecular emission spectra of the vapour plume (10). The invention also relates to a kit and an apparatus for use with the same.
    Type: Grant
    Filed: August 6, 2003
    Date of Patent: November 20, 2007
    Assignee: The Secretary of State for Defence
    Inventors: Sunilkumar Babulal Gandhi, Paul Douglas Jeffery, Gerard David McAnally