Patents Examined by Kevin C Sirmons
  • Patent number: 11033665
    Abstract: A needle assembly includes an outer cannula having a distal end portion, the distal end portion comprising a sharp bevel facilitating insertion of the needle assembly into a subject. The needle assembly further includes an inner cannula slidably disposed coaxially in the lumen of the outer cannula and movable between an extended position and a retracted position, the inner cannula having a blunt distal end portion extending beyond the sharp bevel of the outer cannula whenever the inner cannula is in the extended position. The needle assembly further includes a bias coupled to the inner cannula in a manner favoring automatic positioning of the inner cannula at the extended position. The needle assembly includes a valve located in fluid communication with the lumen of the inner cannula to allow fluid to exit the subject through the inner cannula, and to prevent ingress of fluid into the subject.
    Type: Grant
    Filed: November 3, 2017
    Date of Patent: June 15, 2021
    Assignee: The Arizona Board of Regents on Behalf of The University of Arizona
    Inventors: Peter Rhee, Andrew Tang, Kevin Okarski
  • Patent number: 11006879
    Abstract: A urinary bladder irrigation device includes: a first pipe, a second pipe, a third pipe, a liquid supply member, a liquid collection member, a detection member, and an elevation member. The first pipe has a first opening at one end thereof. The second pipe has a second opening at one end thereof. The third pipe has an end connected to another end of the first pipe and another end of the second pipe and has a third opening at another end thereof. The liquid supply member is connected to the first opening. The liquid collection member is connected to the second opening. The detection member is positioned in the second pipe. The elevation member accommodates the detection member.
    Type: Grant
    Filed: January 24, 2019
    Date of Patent: May 18, 2021
    Assignee: NATIONAL CHENG KUNG UNIVERSITY
    Inventors: Chen-Hsun Weng, Ming-Chien Hung, Wen-Horng Yang, Chien-Hui Ou, Ming-Huang Chen, Chih-Han Chang
  • Patent number: 10940290
    Abstract: Fluid delivery systems and methods of delivering an agent and treating a disorder are disclosed that include a subcutaneously implantable port having a body defining a chamber with an open top and a delivery opening and a septum coupled to the body to extend over the open top of the chamber. The systems and methods can further include an intrathecal catheter having an proximal end configured to be coupled to the port and fluidly coupled to the delivery opening of the chamber and a plug having a body with a passage to receive the intrathecal catheter therethrough. The plug can be configured to be inserted into the fascia to protect against leakage of cerebrospinal fluid.
    Type: Grant
    Filed: August 27, 2018
    Date of Patent: March 9, 2021
    Assignee: ALCYONE LIFESCIENCES, INC.
    Inventors: Deep Arjun Singh, Jonathan Freund, P J Anand, Thomas T. Washburn, Andrew William East, Elsa Chi Abruzzo
  • Patent number: 10940271
    Abstract: The present specification relates to a syringe comprising a barrel, a plunger moveably arranged within the barrel and a plunger rod for driving the plunger, and a mechanism for providing feedback to a user as the plunger rod is moved relative to the barrel for driving said plunger such that feedback is given to a user as the plunger rod is moved relative to the barrel for driving the plunger. The plunger rod is arranged to drive the plunger such that a predetermined relative movement between at least a portion of the plunger rod and the plunger is allowed. The present specification further relates to a plunger assembly wherein a predetermined relative movement between at least a portion of the plunger rod and the plunger is allowed.
    Type: Grant
    Filed: March 31, 2017
    Date of Patent: March 9, 2021
    Assignee: Galderma Holding SA
    Inventor: Anders Holmqvist
  • Patent number: 10926063
    Abstract: The present invention is a decompression needle assembly having a needle that is removable received into to a catheter. The catheter can include a rigid portion and a deformable portion wherein the deformable portion can be multi-ported at its distal end. A one-way valve contained in a catheter hub attached to the catheter wherein the one way valve is in an open position when the needle is received in the catheter. Lateral catheter openings can be defined in the catheter and disposed adjacent to a distal end of the catheter. A plunger can be received within the needle and have an visual and auditory indicator that can be appreciated through the needle hub.
    Type: Grant
    Filed: February 17, 2016
    Date of Patent: February 23, 2021
    Assignee: North American Rescue, LLC
    Inventors: Matt Cupelli, Brent Bronson, Scott Bolleter
  • Patent number: 10918454
    Abstract: A gastrointestinal-tract constricting method comprises: while observing the gastrointestinal tract with an endoscope inserted into the gastrointestinal tract, placing a protection substance, which does not damage tissue, in at least one of a region between the mucosal layer and muscular layer of the gastrointestinal tract and a region in a mucosal surface of the mucosal layer so as to form a protection region that protects the mucosa basal layer from a medical substance that damages the tissue; and, after forming the protection region, supplying the medical substance to a mucosal surface in a target region, which is at a position different from the protection region in a circumferential direction of the gastrointestinal tract, or to a position between the mucosal layer and the muscular layer.
    Type: Grant
    Filed: April 2, 2018
    Date of Patent: February 16, 2021
    Assignee: OLYMPUS CORPORATION
    Inventors: Takuya Okumura, Shunsuke Motosugi, Hiroyuki Morishita
  • Patent number: 10918797
    Abstract: A kit for the direct use of a variety of medical ampoules of differing sizes, with a syringe, the kit having: a syringe body; a syringe plunger having a hollow interior volume; and a plurality of ampoule interface elements, each one being interchangeably received within the hollow interior volume and configured for deployment between an outer surface of the medical ampoule and a surface of the hollow interior volume so as to hold the medical ampoule therein, each of the plurality of ampoule interface elements having an outside diameter sized to fit an inside diameter of the hollow interior volume, wherein a first of the ampoule interface elements has an inside diameter for receiving a medical ampoule of a first size, and a second of the ampoule interface elements has an inside diameter different from the first inside diameter for receiving a medical ampoule of a second size.
    Type: Grant
    Filed: April 11, 2018
    Date of Patent: February 16, 2021
    Assignee: S-VIAL Ltd.
    Inventor: Shlomo Uri Haimi
  • Patent number: 10912933
    Abstract: Provided herein is an implant for delivering a hydrophobic active agent to a target tissue. The implant may include a scaffold defining a first surface and a second surface opposite the first surface, wherein the scaffold is substantially impermeable to a hydrophobic active agent, and a silicone tubing having a wall permeable to the active agent, wherein a first length of the silicone tubing is affixed to the first surface of the scaffold, wherein the two ends of the silicone tubing extend from the first surface, and wherein a path outlined by a second length of the tubing within the first length is circuitous. Also provided is a method of using the implant to locally deliver a hydrophobic active agent to a target tissue, and kits that find use in performing the present method.
    Type: Grant
    Filed: August 18, 2015
    Date of Patent: February 9, 2021
    Assignee: The Regents of the University of California
    Inventors: Pamela Munster, Jim Kiriakis, Hani Sbitany, Scott Thomas
  • Patent number: 10906180
    Abstract: A method and system to monitor and autonomously configure an intravascular assembly without medical staff involvement or presence. In this solution, a robotic device is associated with an intravascular assembly, which has tubing through which fluids are delivered intravenously. Monitoring of the tubing is initiated. In response to the monitoring, an errant flow through the tubing is detected; typically, the errant flow results from one of: a kink or twist in the tubing, an air bubble in the tubing, an occlusion or clot in the tubing, and pressure variations. In response to detecting the errant flow, and in advance of an audible alarm being generated in association with the intravascular assembly, a command is then issued to the associated robotic device. The command is configured to initiate, by the robotic device, physical engagement with and mechanical manipulation of the tubing, thereby remediating the errant flow automatically.
    Type: Grant
    Filed: May 21, 2020
    Date of Patent: February 2, 2021
    Assignee: 123IV, Inc.
    Inventor: Allen B. Chefitz
  • Patent number: 10898693
    Abstract: A method of localized delivery of a therapeutic and/or diagnostic agent to nasal tissue or cavities includes inserting a catheter into a nasal cavity, the catheter having an outer balloon with at least one opening therethrough and an inner surface, and an inner balloon disposed in the outer balloon and at least partially enclosing an inflation chamber and having an outer surface defining a space between the outer surface of the inner balloon and the inner surface of the outer balloon, supplying the agent to the space between the outer surface of the inner balloon and the inner surface of the outer balloon via a first lumen of the catheter, and inflating the inner balloon by supplying fluid to the inflation chamber via a second lumen of the catheter to urge the agent out of the opening in the wall of the outer balloon and into nasal tissue.
    Type: Grant
    Filed: June 24, 2015
    Date of Patent: January 26, 2021
    Assignee: Sanovas Intellectual Property, LLC
    Inventors: Lawrence J. Gerrans, Erhan H. Gunday
  • Patent number: 10898686
    Abstract: Actuators for steerable medical devices are disclosed that not only deflect or steer a portion of a medical device (e.g., a distal portion of a catheter shaft), but also include mechanisms for actively returning the deflected portion of the medical device to an initial configuration (e.g., straight or substantially straight). These active return-to-straight mechanisms may return a catheter shaft from a deflected configuration to a substantially straight configuration throughout a medical procedure, may employ one or more tension members extending along the catheter shaft, and may comprise a gross return actuator and a fine return actuator. For example, the gross return actuator may be configured to partially reverse the deflection of the distal portion of the catheter; and the fine return actuator may be configured to continue reversing the deflection. The gross return actuator may automatically trigger or actuate (mechanically or electromechanically) the fine return actuator.
    Type: Grant
    Filed: September 26, 2018
    Date of Patent: January 26, 2021
    Assignee: St. Jude Medical, Cardiology Division, Inc.
    Inventors: Varun Bansal, Michael Bowers, Troy T. Tegg, David Kim
  • Patent number: 10893881
    Abstract: Systems and methods for treating a blood clot include a catheter to be inserted into a patient. The catheter is used to deliver low stability microbubbles toward the blood clot in the patient. A thrombolytic agent is delivered toward the blood clot, and ultrasonic energy is applied to the microbubbles to vibrate the microbubbles.
    Type: Grant
    Filed: August 28, 2015
    Date of Patent: January 19, 2021
    Assignee: University of Virginia Patent Foundation
    Inventors: Adam Joseph Dixon, John Alexander Hossack
  • Patent number: 10888670
    Abstract: A needle safety system for a syringe having a generally cylindrical barrel extending along a longitudinal axis, the barrel having a hub from which a needle extends distally. The needle safety device has a sleeve at least partially enclosing the needle. A guide track is formed in the sleeve. A multi-part collar disposed in the sleeve has an inner collar which is fixedly connectable to the hub of a syringe barrel. An outer collar is rotatably attached to the inner collar. A guide pin extending radially outwardly from the outer collar slideably engages the guide track. A torqueable compression spring extending between the outer collar and the sleeve biases the sleeve in a distal direction and also biases the outer collar in rotation relative to the sleeve.
    Type: Grant
    Filed: August 13, 2018
    Date of Patent: January 12, 2021
    Assignee: WEST PHARMACEUTICAL SERVICES, INC.
    Inventors: Terry McElroy, Colin Dowling, Patrick Dowling, Martin McGarry
  • Patent number: 10888687
    Abstract: A catheter that prevents excessive concentration of stress while providing sufficient flexibility to a distal end portion of the catheter, even when the catheter is inserted and curved in patient's a blood vessel. Thus, breakage of the catheter at a radiopaque marker is prevented/reduced. The catheter includes a catheter tube and the radiopaque marker, which is disposed in the catheter tube. The radiopaque marker is fixed in the catheter so that a gap is provided between the radiopaque marker and the catheter tube in a radial direction of the catheter tube.
    Type: Grant
    Filed: July 19, 2019
    Date of Patent: January 12, 2021
    Assignee: ASAHI INTECC CO., LTD.
    Inventors: Satoru Matsumoto, Takayuki Hori
  • Patent number: 10869840
    Abstract: Embodiments provide swallowable devices, preparations and methods for delivering viable cells (VC) into the GI tract including GI wall tissue or other tissue site. Particular embodiments provide a swallowable device such as a capsule for delivering VC into an intestinal wall or other site. The VC can be contained within a tissue-penetrating shell disposed in the capsule that protects the VC as they pass through the GI tract until they are inserted into GI tract tissue or other location. The shell desirably has shape, size and material consistency to be contained in a swallowable capsule, delivered from the capsule into solid tissue by the application of force on the shell and biodegrade within the solid tissue to release the VC into the tissue. Within the shell or other structure the VC can be maintained in a viability-sustaining gel that preserves the viability of the VC for selected time periods.
    Type: Grant
    Filed: March 9, 2017
    Date of Patent: December 22, 2020
    Assignee: InCube Labs, LLC
    Inventors: Mir Imran, Joel Harris
  • Patent number: 10869966
    Abstract: A syringe system, piston seal systems, stopper systems, and methods for assembling and using the syringe systems. The piston seal system including a piston seal member and a piston head member. The injection system including a container, a piston seal system positioned within the container, and a stopper system coupled to an end of the container. The method of assembling an injection system, the method includes obtaining a container, a piston seal system, and a stopper system. The method also includes inserting the piston seal system into a cavity within the container. The method further includes securing the stopper system at an end of the container in an opening of the cavity. Methods of using the syringe system, piston seal systems, and stopper systems are also disclosed.
    Type: Grant
    Filed: February 19, 2016
    Date of Patent: December 22, 2020
    Assignee: Regeneron Pharmaceuticals, Inc.
    Inventors: Michael Cupicha, Alexei Goraltchouk, Ian Hart, Mike Stelmah
  • Patent number: 10869971
    Abstract: An apparatus for use with a syringe for providing a safety syringe, the apparatus including a sheath (100; 300; 500) deployable for at least partially covering a needle (126) of the syringe; and a sheath actuator (102; 302; 502) for deploying the sheath by interaction with a sheath deployment mechanism (104; 304; 504); the sheath being configured to be stationary in relation to the needle until a syringe plunger (116; 316; 516) reaches a sheath release point on its inward stroke, and the sheath actuator being configured for deployment of the sheath on movement of the sheath actuator relative to the syringe plunger after the sheath release point.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: December 22, 2020
    Assignee: Owen Mumford Limited
    Inventor: Damian Alexander Holland
  • Patent number: 10864145
    Abstract: A male connector (1) includes a luer portion (10) connected to the upstream end of a tube (8) used in enteral feeding, and a lock portion (20) that is removably attached to the luer portion. The luer portion (10) includes a tubular male luer (11) in which a channel (17) in communication with the tube (8) is formed. The lock portion (20) has a hollow tubular shape and is open at two ends, and includes female threading (21) that opposes the male luer on the inner circumferential face of the lock portion (20). The male luer (11) is inserted into the lock portion (20). Rotation prevention mechanisms (16, 26) that engage with one another are provided on the luer portion (10) and the lock portion (20) such that the lock portion (20) does not rotate relative to the luer portion (10).
    Type: Grant
    Filed: December 9, 2014
    Date of Patent: December 15, 2020
    Assignee: JMS CO., LTD.
    Inventors: Yasumasa Uehara, Yutaka Ueda, Kazuhiko Takimoto, Megumi Harada
  • Patent number: 10864321
    Abstract: An external medical device includes a fluid inlet, an inlet valve in fluid communication with the fluid inlet to control fluid flow through the fluid inlet in response to fluid inlet control signals, a fluid outlet in fluid communication with a fluid reservoir, a fluid pump configured to deliver a therapeutic fluid from the fluid reservoir through the fluid outlet in response to fluid outlet control signals, a fluid sensor configured to monitor the therapeutic fluid between the fluid pump and the fluid outlet and further configured to output sensor data corresponding to a monitored condition of the therapeutic fluid, and a control module configured to receive the sensor data and output, based on the sensor data, the fluid inlet control signals to the inlet valve and the fluid outlet control signals to the fluid pump.
    Type: Grant
    Filed: January 10, 2020
    Date of Patent: December 15, 2020
    Inventors: Thomas Leroy Schmitz, Jesse James Corry
  • Patent number: 10857372
    Abstract: The present application relates to a device for treating skin using non-thermal plasma. It comprises a housing having a skin interface electrode for application to skin during treatment, a generator for generating non-thermal plasma at the skin interface electrode; and an isolating element to isolate a region surrounding said skin interface electrode other than during treatment so that non-thermal plasma generated at the skin interface electrode within said region sterilises the skin interface electrode.
    Type: Grant
    Filed: May 19, 2016
    Date of Patent: December 8, 2020
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Jasper Zuidervaart, Eduard Antonius Van Der Zwan, Stephan Mooibroek, Jeroen Christian Nijdam