Abstract: The subject matter of this disclosure generally relates to a medical device system and related methodologies that leverage data associated with the use of a meal transaction application, such as an application for ordering food delivery. Data generated by the meal transaction application can be leveraged by a patient care system or application for purposes of diet or calorie logging. Alternatively or additionally, the meal transaction data can be leveraged for purposes of controlling the administration of therapy by a medication delivery system, such as an insulin infusion pump.

Abstract: A pen needle includes a hub supporting a needle and a distal needle shield that can retract to expose the needle and return to an extended position to cover the needle. A proximal needle shield moves to an extended position to cover a proximal end of the needle. A spring extends between the distal and proximal needle shields to bias the distal and proximal needle shields to their respective extended positions. A locking member on the distal needle shield cooperates with the hub to lock the proximal and distal needle shields in their respective extended positions. An indicator in the hub couples to the distal needle shield when the distal needle shield is moved to a retracted position. The indicator moves with the distal needle shield to the extended position of the distal needle shield where the indicator indicates that the pen needle is no longer usable.

Abstract: A drug delivery assembly is used for delivering a medicament to a patient. The assembly includes a housing having upper and lower surfaces and a sidewall, with an actuator associated with the sidewall. An adhesive pad, configured to attach to a human body surface, is associated with the lower surface of the housing. The assembly also includes a drug reservoir positioned within the housing, associated with a needle movably associated with the drug reservoir. The actuator is moved from a first position to a second position to deploy the needle, with movement of the actuator being generally perpendicular to movement of the needle.

Abstract: A phototherapy device, system, and method for treating acne and/or acne scarring, includes a light emitting device configured and arranged to emit light from a bottom surface thereof; and an attachment portion having an aperture therethrough configured to permit light through. The attachment portion is configured to retain the device to a user's skin and bathe the skin with phototherapeutic light from the light emitter. Attachment of the device may be preceded with the application of synergistic fluid, ointment, gel, cream, lotion, foam, soap, or other solutions which may or may not consist of known topical acne treatment agents, augment device attachment to the skin, and/or have photodynamic properties. The light emitted may be any wavelength, combinations of wavelengths, intensity, pulse frequency, and exposure duration.

Abstract: A prefilled syringe safety device and injector for use with a syringe. The prefilled syringe safety device and injector includes a cartridge, a casing, a tube, a biasing member, a ring and a plunger slider. The cartridge supports the syringe therein. The cartridge is supported within the casing. The tube includes a tube distal end. The tube is slidably engaged with the cartridge and can be in an extended state and in a retracted state. When in the retracted state, the needle of the syringe extends beyond the tube distal end and the casing distal opening. The biasing member is engaged with the cartridge and the tube so as to bias the tube in the extended state. The ring includes a protrusion and is engaged with the tube and the biasing member. The protrusion is positioned within the track. The plunger slider engages with the plunger of the syringe.

Abstract: A device is provided for supplying electrical current to an intervertebral disc. The device comprises a cannula having a proximal end and a distal end and a longitudinal axis therebetween. The distal end comprises a beveled tip for contacting a region of the intervertebral disc, and an electrode disposed within or on a surface of the cannula adjacent to the distal end. The electrode is configured to discharge the electrical current to the region of the intervertebral disc. Methods of diagnosing and/or treating discogenic back pain are also provided.

Abstract: An enteral dosing control coupling comprising a cylindrical collar defining a hollow internal chamber and a lumen extension tip projecting axially into the internal chamber, the lumen extension tip defining an internal lumen extending through the lumen extension tip. In example forms, the lumen extension tip is integrally formed with the cylindrical collar. In other example forms, the lumen extension tip is a separate piece and is removably engageable within the cylindrical collar.

Abstract: An enteral adapter assembly for connecting an enteral fluid source to an enteral feed tube, the enteral adapter assembly comprising: an adapter including: a proximal end comprising a first connection portion for attaching to a fluid outlet provided on the enteral fluid source, and a distal end comprising a first threaded connection portion for screwing to an end of the enteral feed tube. A fluid conduit extends between the proximal and distal ends. The assembly comprises a removable cap having a second threaded connection portion configured for screwing the cap onto the first threaded connection portion, wherein the proximal end of the adapter comprises a locking member configured to irreversibly mate with a corresponding feature provided on the fluid outlet as the adapter is attached to the outlet to prevent removal of the adapter from the outlet when the cap is unscrewed from the distal end of the adapter.

Abstract: A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.

Abstract: A vascular access system may include a catheter adapter and an extension set. The extension set may include a first end having a first connector coupled to the catheter adapter, a second end having a second connector, an extension tube disposed between the first end and the second end, and a brace configured to hold the extension tube in a curved position. The extension set may alternatively include a housing disposed between the first connector and the extension tube, where the housing is U-shaped or V-shaped and a fluid pathway extends through the housing.

Abstract: An endovascular catheter, with a catheter shaft including a first lumen and a shaft opening, a deflection element, and a controlling element. The first lumen and the shaft opening communicate with each other. The deflection element is rotatably arranged inside the catheter shaft, and configured to deflect a guidewire through the shaft opening. The controlling element is operably connected with the deflection element and configured to rotate the deflection element in a first rotating direction. Furthermore, the present invention refers to a catheter assembly with the endovascular catheter and the guidewire.

Abstract: Systems and methods are provided for signaling a condition of an infusion assembly. An example system may comprise an elastomeric pump that includes a chamber for receipt of a volume of fluid, an outer layer configured to expand and contract as the chamber receives and dispenses the fluid, and a passive indicator provided on the outer layer for signaling a change in the volume of the fluid in the chamber. The example system further may comprise an image capture device configured to capture an image of the pump, and a processing system configured to process the image to signal the condition of the infusion assembly to a user of the system. An example method may comprise capturing the image of the pump; processing the image; and displaying information to the user of the pump to communicate a condition of the pump to the user. Various elastomeric pumps for infusion assemblies also are provided.

Abstract: A device for clearing obstructions from a medical tube is disclosed. The device includes an enclosure having an interior and an exterior, the enclosure comprising a distal opening for providing access to the interior of the enclosure. The device further includes a spool provided within the enclosure that is rotatable about an axis and an elongated guide member coupled to the spool such that the rotation of the spool causes the elongated guide member to wind or unwind about the spool. The device further includes a drive mechanism that is operable to rotate the spool within the enclosure without compromising a sterile field within the enclosure.

Abstract: Apparatuses and methods for continuous injection of fluid, in some examples the apparatuses may include a manifold, a pair of reciprocating pistons, and an actuation control that may apply both suction (aspiration) and injection of fluid as part of the same actuation. The apparatuses and methods may be configured to simplify operation of a continuous fluid injection apparatus, including operations that include an aspiration an injection of fluid to confirm the absence/presence of blood prior to injection.

Abstract: A surgical access device includes a cannula body, an obturator assembly, and a fixation mechanism. The fixation mechanism includes at least one wing, a first plurality of magnets disposed on an elongated portion of the obturator assembly, and a second plurality of magnets disposed on the at least one wing. The at least one wing is coupled to an elongated portion of the cannula body and is movable between a first position where the at least one wing is parallel to a longitudinal axis, and a second position where the at least one wing is disposed at an angle to the longitudinal axis. A predetermined amount of translation of the elongated portion of the obturator assembly within a channel of the elongated portion of the cannula body causes the at least one wing to move from the first position to the second position.

Abstract: Methods of restoring homeostatic capacity of a subject are provided. Aspects of the invention further include compositions, systems and devices for practicing the methods. The methods and compositions described herein find use in a variety of applications. Aspects of certain embodiments of the methods include modulating a subject's autonomic nervous system in a manner sufficient to restore the homeostatic capacity of the subject. Aspects of other embodiments of the invention include administering to the subject an amount of an apoptosis modulator effective to at least partially restore homeostatic function of the neuroendocrine system of the subject.

Abstract: A dispensing device to deliver a multiple component material to a location in vivo. The device includes a manifold having proximal and distal ends and multiple separate lumens within it, connectable on its proximal end to multiple syringes for containing the multiple component material, a distal tip assembly comprising a tip connector having separate side-by-side lumens within the tip connector and optionally a dispensing tip, and multiple flexible side-by-side cannulae. Each cannulae has a proximal end and a distal end, the proximal ends of the cannulae are connected to a separate lumen at the distal end of the manifold, and the distal ends of the cannulae are connected to one of the side-by-side lumens of the tip connector, establishing a fluid communication between the manifold and the distal tip assembly, wherein the side-by-side cannulae are optionally partially connected along their length and are split at their proximal and distal ends.

Abstract: An apparatus for delivering an active ingredient into skin of an animal at a defined depth, the apparatus including: a microprojection array including a plurality of microprojections having a density of at least 2,000 projections per cm2; and an applicator that drives the microprojection array towards the skin in use so that the microprojection array impacts on the skin with a mass-to-velocity ratio of between 0.0005 g/m/s and 0.1 g/m/s per cm2.

Abstract: A device for expression and collection of breast milk, the device includes an actuatable assembly and a breast interface. The breast interface is sized to receive a breast and form a fluid tight seal against the breast. The breast interface includes an expandable membrane disposed within at least a portion of the breast interface. The expandable membrane reversibly deforms in response to actuation of the actuatable assembly, thereby applying vacuum pressure at the breast to express the breast milk. The expandable membrane comprises a plurality of expandable pleats which extend radially outward from a central longitudinal axis of the breast interface.

Abstract: The disclosure relates to a medicament delivery device including an activating mechanism, wherein the activating mechanism includes a hollow injection needle, a cartridge containing a dosage of a medicament, a cartridge carrier including at least one resilient arm for holding the cartridge, a removable needle cap for covering the injection needle, and a drive element adapted to couple with the cartridge, wherein the cartridge is retained in a position spaced apart from the injection needle in a proximal direction (P) by the at least one resilient arm when the medicament delivery device is in an initial position (P1), and wherein by removing the needle cap, the cartridge is releasable to be pushed into a distal direction (D) by the drive element with respect to the cartridge carrier.