Abstract: A pump and a pump controller which uses an algorithm to quickly achieve and maintain a stable plasma field in a surgical site are provided. The algorithm calculates an electrical characteristic value to determine if a suction rate by the pump should be increased or decreased to achieve the stable plasma field. A method of using the pump and the pump controller is also provided.

Abstract: In vivo positionable filtration devices are provided that filter one or more therapeutic agents in blood flowing in a blood vessel. The filtration devices include an elongated member and a filtering component coupled to the elongated member. The elongated member and the filtering component are dimensioned for positioning within the blood vessel. Further, the filtering component includes a filtration material to filter the one or more therapeutic agents from the blood. Methods of in vivo filtration of the one or more therapeutic agents are also provided. The methods include positioning a filtration device of the filtration devices in the blood vessel, and administering a therapeutic agent of the one or more therapeutic agents upstream from a target tissue site to direct flow of the therapeutic agent to the target tissue site and then to the filtration device. The filtration device is positioned downstream from the target tissue site.

Abstract: An improved hiatal hernia treatment enhances recovery after surgery by reducing a patient's pain at an area of treatment. The area of treatment contains the hiatal hernia and must be extensively divided before the hiatal hernia can be treated. The improved hiatal hernia treatment reduces the patient's pain through directed application of an anesthetic via an applicator positioned within the area of treatment. The reduction of the patient's pain increases the patient's comfort, reduces the need for pain medication, and lowers the patient's blood pressure to enhance recovery.

Abstract: An injection device includes a lower housing, a needle guard and an upper housing. With the upper housing in a pre-use position and the needle guard in a first position, an abutment body of an arm of the upper housing abuts a catch of the lower housing, preventing the upper housing from moving distally relative to the lower housing toward a dispensed position. Proximal movement of the needle guard from the first position to a second position thereof causes proximal movement of a camming ramp of a leg of the needle guard with respect to the catch and the abutment body such that the camming ramp engages the arm, thereby deflecting the abutment body radially outwardly by a distance sufficient to allow the abutment body to pass radially outside of the catch, and, in turn, permits the distal movement of the upper housing into the dispensed position of the upper housing.

Abstract: A drug depot delivery system includes a housing having a cavity. A cartridge is positioned within the cavity and includes a body having a channel. The body includes a first pair of rails and a second pair of rails. A plunger is slidably disposed in the housing and the cartridge. The plunger is configured to move a drug depot through the channel and out of the housing. Kits and methods of use are disclosed.

Abstract: A device for coupling to a fluid connector of an IV administration set to resist contamination of the fluid connector and IV administration set and permit priming of the IV administration set. The device including a cover body having a cavity for receiving the fluid connector, a priming passage for priming fluid from the IV administration set through the fluid connector, and a coupling tab extending from the cover body, the coupling tab permitting the cover body to be coupled to a length of an IV line or other portion of the IV administration set to resist contamination and permit priming of the IV administration set.

Abstract: Systems and methods are provided for injecting one or more agents into tissue within a patient's body. In one embodiment, an injection device is provided that includes an outer tubular member comprising a proximal end, a distal end sized for introduction into the patient's body, and a lumen extending between the proximal end and the distal end; a relatively small cross-section needle tip extending distally beyond the distal end; and an internal pressure release member slidably disposed within the lumen between a distal position and a proximal position to prevent viscous injectate from expressing from the needle tip.

Abstract: A female syringe barrel is disclosed, which includes two protrusions provided on a cylindrical portion. A length (Lp) of each protrusion of the two protrusions along a direction, perpendicular to an axis of the cylindrical portion and perpendicular to a direction in which each protrusion of the two protrusions protrudes from the cylindrical portion, is 2.0 mm to 4.5 mm. A width of each protrusion of the two protrusions along an axial direction of the cylindrical portion is 1.0 mm to 2.1 mm. Each protrusion of the two protrusions has an inclined surface, which opposes a trailing flank of a screw when the two protrusions are engaged into the screw of a lock adapter, in an end portion close to a barrel body.

Abstract: A medicament delivery device includes a device housing for placing on the skin of a patient, the housing including a needle aperture; a needle for injecting a medicament, the needle arranged to pass through the needle aperture; and sensors configured to provide a signal when the housing is placed on the skin of the patient. The sensors are arranged around the needle aperture.

Abstract: A medication delivery system having a holding chamber capable of delivering dosages of medicament from a metered dose inhaler. The holding chamber includes an actuator detector, a flow detector, and a display. In another embodiment, a medication delivery system includes a holding chamber having an input end and an output end, a metered dose inhaler operably coupled to the input end of the holding chamber, and a metered dose inhaler identifier associated with the holding chamber and operable to identify the metered dose inhaler coupled to the holding chamber.

Abstract: A system for drawing a solution is provided. The system includes a filter, a vacuum source, and an actuator. The filter has an input port, a first output port, a second output port, and a flow path defined in part by the input port and the second output port. The vacuum source is in fluid communication with the first output port and operative to apply a vacuum to the flow path. The actuator is operative to facilitate movement of the solution along the flow path.

Abstract: Methods, systems, and devices for facilitation of intraluminal medical procedures within the neurovasculature, the methods, systems and the devices including catheters and catheter advancement elements.

Abstract: Provided herein is an implant for delivering a hydrophobic active agent to a target tissue. The implant may include a scaffold defining a first surface and a second surface opposite the first surface, wherein the scaffold is substantially impermeable to a hydrophobic active agent, and a silicone tubing having a wall permeable to the active agent, wherein a first length of the silicone tubing is affixed to the first surface of the scaffold, wherein the two ends of the silicone tubing extend from the first surface, and wherein a path outlined by a second length of the tubing within the first length is circuitous. Also provided is a method of using the implant to locally deliver a hydrophobic active agent to a target tissue, and kits that find use in performing the present method.

Abstract: Disclosed herein are improved methods and apparatuses for providing hemostasis within a cavity defined by an internal surface of a bleeding tissue space. A catheter comprising a proximal end and a distal end may be advanced into the cavity through a proximal opening of the tissue space into the cavity. A distal balloon coupled to the catheter may be expanded, and the catheter tensioned to apply pressure to the internal surface of the tissue space to inhibit bleeding of the tissue space.

Abstract: A fluid management system includes a pump configured to pump fluid through the system at a fluid flow rate. The system includes a processor including a user interface, the user interface allowing a user to input a set of system operating parameters, the processor being configured to control the pump to maintain a target fluid flow rate based on the set of system operating parameters. The system further includes a scope device coupled to the pump to deliver the fluid to a target surgical site, the scope device including an elongated shaft extending from a distal end thereof, the elongated shaft including at least one sensor, the at least one sensor transmitting sensor data relating to the target surgical site to the processor. The processor automatically signals to the pump to adjust the fluid flow rate based on the sensor data.

Abstract: An implantable drug delivery device and method for delivering a drug to a living body. The device includes a housing having at least one opening, a reservoir within the housing adapted to contain the drug, a temporary seal closing the at least one opening of the housing, and a heating element in thermal contact with the temporary seal. The heating element is adapted to generate heat in response to a magnetic field to melt the temporary seal and release the drug within the reservoir through the at least one opening of the housing.

Abstract: A fluid sensing apparatus and method for detecting pressure and a presence of a bubble within a fluid tube. The fluid sensing apparatus comprises a housing configured to receive a portion of the fluid tube and to house a pressure sensor and an ultrasonic transmitter. The pressure sensor is positioned adjacent the fluid tube and is configured to receive a pressure sensor signal, which correlates to a detected pressure differential within the fluid tube. A controller transmits a drive signal to the ultrasonic transmitter, which emits ultrasonic waves through a portion of the fluid tube and to the pressure sensor. The pressure sensor receives both the ultrasonic waves and the pressure sensor signal, and subsequently transmits an output signal to the controller. In a presence of the detected pressure differential or the bubble within the fluid tube, the output signal will exhibit a DC shift or a distortion of signal characteristics of the output signal, respectively.

Abstract: An apparatus produces medical foam for wound care or hair stimulation. The apparatus includes a foam generation unit having a fluid reservoir, a fluid delivery line and a foam generation tip. The apparatus also includes a compressed gas unit having at least one container of compressed gas, a source of electric power, and a gas regulator valve. A supply of wound care or hair stimulating solution is communicably connected to the foam generation tip such that when the apparatus is operated the medical foam is produced by the foam generator tip.

Abstract: A medicament delivery device is presented having a drive configured to act on a medicament container for expelling a medicament; a holder configured to hold said drive in a pre-tensioned state; an activator configured to interact with said holder for releasing said drive from the pre-tensioned state; wherein the device further includes a feedback mechanism configured to interact both with said holder and with said drive for generating an audible and/or tactile and/or visual signal indicating that the medicament has been completely expelled.

Abstract: A check valve includes an upper housing defining an inlet of the check valve, a lower housing defining an outlet of the check valve, and a cavity interposed between and defined by the upper and lower housings for fluidly connecting the inlet and the outlet. The check valve further includes a valve member mounted in the cavity to selectively permit fluid flow in a first direction, and prevent fluid backflow in a second direction opposite to the first direction. The valve member includes a valve body and a valve stem portion extending axially through a central axis of the valve body. The valve member may further include a plurality of feet disposed about and extending longitudinally from an outer circumferential perimeter of the valve body.