Patents Examined by Kevin C Sirmons
  • Patent number: 11364146
    Abstract: An ophthalmic device including a cannula having a cannula distal end, a lumen, and one or more orifices coupled to the lumen is provided. The cannula is configured to deliver a fluid. A sleeve is disposed around the cannula and has a sleeve distal end. A handle is coupled to the sleeve and the cannula, the handle having an actuator. An internal mechanism is coupled to the actuator and configured to retract the sleeve relative to the cannula. The internal mechanism includes a follower fixedly coupled to the sleeve and moveable between distal and proximal positions, and a release member movable between an activated position and a release position. The release member is coupled to the actuator and configured to release a force that urges the follower from the distal position to the proximal position when the release member moves from the activated position to the release position.
    Type: Grant
    Filed: July 21, 2021
    Date of Patent: June 21, 2022
    Inventors: Malik Y. Kahook, Eric Porteous, Carlos A. Mendoza
  • Patent number: 11357961
    Abstract: The invention relates to a connector (1) for connecting a catheter (2) to a fluid transfer system comprising a main body (11) with a tubular pin (111) adapted to be inserted into an end portion (21) of the catheter (2) such as to provide a fluid connection between the catheter (2) and the tubular pin (111). The connector (1) is characterized in that a fixing means (12) is movably connected to the main body (11), wherein the fixing means (11) is adapted to fix the catheter (2) to the connector (1) when the fixing means (12) is in a fixing position.
    Type: Grant
    Filed: April 21, 2017
    Date of Patent: June 14, 2022
    Assignee: Fresenius Kabl Deutschland GmbH
    Inventor: Barbara Amon
  • Patent number: 11357918
    Abstract: A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.
    Type: Grant
    Filed: October 15, 2018
    Date of Patent: June 14, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Richard James Vincent Avery, Malcolm Stanley Boyd, Oliver Charles Gazeley, Gareth James Lewis, David Aubrey Plumptre, James Alexander Senior
  • Patent number: 11351343
    Abstract: The present invention is a simple-to-use IV placement assist device with an added safety feature. A catheter advancer is slidably integrated with a base to guide advancement of a catheter linearly along the insertion path of the needle and catheter. A safety feature is engaged by a movable component moving from a first position to a second position, such movable enabling relative movement between the base and catheter advancer and/or catheter assembly, rotation of the needle about its length axis, and/or minor advancement of the catheter assembly to sheath the tip of the needle. The IV placement assist device stabilizes and guides the critical needle insertion and catheter advancement steps of a complication-prone and very common procedure.
    Type: Grant
    Filed: July 19, 2018
    Date of Patent: June 7, 2022
    Assignee: INNOVITAL, LLC
    Inventors: Amit Shah, Curt Kothera, Pablo Sztein
  • Patent number: 11351354
    Abstract: An extension set may include a clamp, which may include a housing and an actuator. The actuator may be movable between a raised position and a depressed position with respect to the housing. The actuator may include a bump profile. The extension set may include an extension tube, which may be disposed within the housing. The extension tube may include a loop. In response to movement of the actuator between the raised position and the depressed position with respect to the housing, the bump profile may progressively clamp the extension tube along the loop. The loop may facilitate an increased fluid volume flowing distally towards a catheter in response to actuating the clamp.
    Type: Grant
    Filed: February 18, 2020
    Date of Patent: June 7, 2022
    Assignee: Becton, Dickinson and Company
    Inventor: Joseph Spataro
  • Patent number: 11351328
    Abstract: A breathing circuit for delivering heated, humidified gases to a patient for medical purposes is described, comprising a humidifier chamber holding a quantity of water, a blower unit that delivers a pressurized gases stream to the chamber inlet, and a control system that adjusts output parameters of the breathing circuit, the circuit including a heater plate which heats the water in the chamber so that gases flowing through the chamber become heated and humidified, the circuit also including a gases transportation pathway and patient interface to convey heated humidified gases to a patient, the gases transportation pathway including an RFID tag located at the patient end which senses a parameter of the gases passing through the pathway, the control system including an RFID interrogator interrogating and receiving data relating to the sensed parameter from the RFID tag in real time, and adjusting the output parameters of the breathing circuit accordingly.
    Type: Grant
    Filed: October 10, 2018
    Date of Patent: June 7, 2022
    Assignee: Fisher & Paykel Healthcare Limited
    Inventors: Andrew Robert Donald Somervell, Nordyn Alami, Dexter Chi Lun Cheung, Christopher Simon James Quill, Matthew Jon Payton
  • Patent number: 11344314
    Abstract: Microcatheters and methods for modifying and delivering suspended particles to target bodily parts (e.g., of a cardiovascular system). Embolization microcatheters and uses thereof in performing local embolization procedures, involving modifying flow characteristics (momentum) of suspensions during delivery. Applicable for delivering embolization material in a small blood vessel towards a target bodily part, and for performing local embolizations in small blood vessels feeding (possibly, cancerous) target bodily parts, thereby forming emboli therein, while preventing or minimizing non-target embolization.
    Type: Grant
    Filed: March 2, 2016
    Date of Patent: May 31, 2022
    Inventors: Michael Gabriel Tal, Eran Miller
  • Patent number: 11338095
    Abstract: The disclosure relates to a drug delivery device, comprising: a housing to receive a cartridge with a needle and a stopper, wherein the cartridge is movable within the housing so as to cover the needle within the housing or advance the needle beyond the housing, a gas tank containing a pressurized gas within the housing, the gas tank connectable with a cavity for moving the cartridge, a cavity for moving the stopper and a cavity for moving the cartridge, a release member fixed to the housing and adapted to restrict movement of the cartridge relative to the housing in a proximal direction, a membrane between the cavity and the retraction release member adapted to operate the release member if the membrane is deformed by a pressure within the cavity exceeding a predetermined value allowing movement of the cartridge relative to the housing in the proximal direction.
    Type: Grant
    Filed: July 12, 2017
    Date of Patent: May 24, 2022
    Assignee: Sanofi-Aventis Deutschland GMBH
    Inventor: Christian Rehbein
  • Patent number: 11331457
    Abstract: A balloon catheter is disclosed having a balloon at a distal portion of a catheter shaft and on a surface of the balloon are elongate bodies which are crystals of a water-insoluble drug having independent long axes. The balloon in a deflated state has a plurality of wing portions in a circumferential direction of the balloon, and a circumferential surface portion along a circumferential direction of the catheter shaft, the plurality of wing portions being folded along the circumferential direction of the balloon. A surface of the circumferential surface portion which faces the plurality of wing portions that are folded has a region in which tip portions are not in contact with the surface of the balloon or with other elongate bodies, and a surface which faces the plurality of wing portions that are folded which faces an outer circumferential side has a region in which the tip portions are in contact with the surface of the balloon or with the other elongate bodies.
    Type: Grant
    Filed: September 20, 2018
    Date of Patent: May 17, 2022
    Inventors: Hiroshi Goto, Katsumi Morimoto, Yasuo Kurosaki
  • Patent number: 11324861
    Abstract: Syringe plunger rods comprising an elongate body formed from a composition comprising one or more of virgin material, a sterilization-stable recycled resin and a biobased compositions are described. Plunger rods comprising a plurality of ribs, some of which may have a plurality of openings, are also described. The plunger rods requiring less material while maintaining sufficient structural integrity to function properly.
    Type: Grant
    Filed: September 28, 2015
    Date of Patent: May 10, 2022
    Assignee: Becton, Dickinson and Company
    Inventors: Ankur S. Kulshrestha, Yan Yevmenenko, Dinesh S. Kommireddy, Andrew Wong, Behzad Mottahed, Michael V. Quinn, Mildred Calistri-Yeh, Lourdes Pia L. Amora
  • Patent number: 11324935
    Abstract: Provided herein is an implant for delivering a hydrophobic active agent to a target tissue. The implant may include a scaffold defining a first surface and a second surface opposite the first surface, wherein the scaffold is substantially impermeable to the hydrophobic active agent, and a silicone tubing having a wall permeable to the hydrophobic active agent, wherein a first length of the silicone tubing is affixed to the first surface of the scaffold, wherein two ends of the silicone tubing extend from the first surface, and wherein a path outlined by a second length of the silicone tubing within the first length is circuitous. Also provided is a method of using the implant to locally deliver the hydrophobic active agent to the target tissue, and kits that find use in performing the present method.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: May 10, 2022
    Assignee: The Regents of the University of California
    Inventors: Pamela Munster, Jim Kiriakis, Hani Sbitany, Scott Thomas
  • Patent number: 11318304
    Abstract: The present invention provides a system and a method for measuring an impedance of one or more target cells before and after an electroporation protocol has been applied to the one or more target cells. A result of the impedance measurement provides a feedback control that can be implemented during and/or after the electroporation protocol to customize an electrical treatment for a particular target cell or cellular tissue.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: May 3, 2022
    Assignee: University of South Florida
    Inventors: Mark Jeffrey Jaroszeski, Timothy Fawcett, Richard Jason Connolly, Andrew M. Hoff, Reginald Morley Atkins, Douglas Walter Brown, Richard A. Gilbert
  • Patent number: 11291775
    Abstract: A medicament delivery device is presented having a drive mechanism configured to act on a medicament container for expelling a medicament; a holding mechanism configured to hold said drive mechanism in a pre-tensioned state; an activation mechanism configured to interact with said holding mechanism for releasing said drive mechanism from the pre-tensioned state; wherein the device further includes a feedback mechanism configured to interact both with said holding mechanism and with said drive mechanism for generating an audible and/or tactile and/or visual signal indicating that the medicament has been completely expelled.
    Type: Grant
    Filed: February 25, 2020
    Date of Patent: April 5, 2022
    Assignee: SHL MEDICAL AG
    Inventor: Mattias Daniel
  • Patent number: 11285266
    Abstract: A drug delivery device includes a reservoir, a drug delivery member in fluid communication with the reservoir, and a plunger disposed in and moveable relative to the reservoir. A plunger rod has a mass MP and is movable from (i) a first position, where the distal end of the plunger rod is spaced apart from the plunger to (ii) a second position, where the distal end of the plunger rod contacts the plunger. A drive mechanism is coupled to the proximal end of the plunger rod and is configured to deliver a drive force FD to move the plunger rod from the first position to the second position. A ratio of the mass of the plunger rod to the drive force of the drive mechanism (MP/FD) is in a range of approximately a value greater than 0 kg/kgf to approximately 0.05 kg/kgf.
    Type: Grant
    Filed: May 15, 2017
    Date of Patent: March 29, 2022
    Assignee: AMGEN INC.
    Inventors: Sean Fitzgibbon, Julian Jazayeri
  • Patent number: 11278718
    Abstract: A nerve cuff for establishing a nerve block on a nerve can have a cuff body with a channel for receiving a nerve, a reservoir for holding a drug, and an elongate opening slit extending the length of the cuff body that can be opened to provide access to the channel and can be closed to enclose the cuff body around the nerve. The nerve cuff can also include an electrode for detecting and measuring electrical signals generated by the nerve. A controller can be used to control delivery of the drug based on the electrical signals generated by the nerve.
    Type: Grant
    Filed: February 7, 2020
    Date of Patent: March 22, 2022
    Assignee: SetPoint Medical Corporation
    Inventors: Michael A. Faltys, Jacob A. Levine, Jesse M. Simon
  • Patent number: 11273239
    Abstract: A breast milk expression apparatus includes at least one compression pad disposable about a breast of a user and configured for radial displacement relative to the breast. The apparatus includes a compression unit coupled to the at least one pad, configured to cyclically displace the at least one pad radially inwardly to cause compression of the breast and, following compression of the breast, permitting the breast to expand and decompress.
    Type: Grant
    Filed: February 9, 2018
    Date of Patent: March 15, 2022
    Assignee: IMALAC, INC.
    Inventors: Noreen Gordon Sablotsky, Rachael Sablotsky Kish, Kathryn Garriott Sablotsky, Scott R. Arp, William Thomas Bales, Paul John Grata, Damian H. Tomlin, Victor M. Gamez, Lisandro Rivera Alvarez
  • Patent number: 11260176
    Abstract: An autoinjector (100?) for expelling a single dose of a drug from a held cartridge (600) comprising a piston (630). The autoinjector includes a needle shield (350, 380?) axially movable from an initial extended position via a triggering position to a trigger release position. The needle shield (350, 380?) is operatively coupled to a plunger release element (320?, 1320) cooperating with a plunger (310, 400) to define a releasable retaining mechanism that retains the plunger release element (320?, 1320) threadedly engaged with a base thread component (204?, 1204) in a predefined relative rotational and axial position and against rotational bias provided by an actuator (330). The needle shield (350, 380?) is configured for operating the retaining mechanism to release the retaining of the plunger release element (320?, 1320) and the base thread component (204?, 1204) from the predefined relative rotational and axial position upon the needle shield (350, 380?) being moved into the trigger release position.
    Type: Grant
    Filed: December 29, 2016
    Date of Patent: March 1, 2022
    Assignee: Novo Nordisk A/S
    Inventor: Soeren Kjellerup Hansen
  • Patent number: 11253287
    Abstract: A device and method for establishing retrograde blood flow during recanalization of a vessel having a targeted blockage. While in a collapsed state an occluding component is introduced distally intravascularly traversing the targeted blockage to its distal side. Then, the occluding component transitions to an expanded state having an enlarged diameter forming a seal with an internal wall of the vessel prohibiting anterograde blood flow beyond the expanded occluding component. Retrograde blood flow is thereby established in a region of the vessel bound at one end by the occluding component and at an opposite end by the targeted blockage by dispensing a flushing fluid into the region of the vessel.
    Type: Grant
    Filed: October 4, 2018
    Date of Patent: February 22, 2022
    Inventor: Ray McCarthy
  • Patent number: 11253646
    Abstract: Systems and methods are provided for injecting one or more agents into tissue within a patient's body. In one embodiment, an injection device is provided that includes an outer tubular member comprising a proximal end, a distal end sized for introduction into a patient's body, and a lumen extending between the proximal and distal ends; a relatively small cross-section needle tip extending distally beyond the distal end, and an internal pressure release member slidably disposed within the lumen between a distal position and a proximal position to prevent viscous injectate from expressing from the distal tip.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: February 22, 2022
    Inventors: Stephen A. Leeflang, Christian S. Eversull
  • Patent number: 11246983
    Abstract: An infusion device includes a pump for pumping a medical fluid from a fluid container through a delivery line towards a patient at a flow rate, a sensor for measuring a force on the pump or the delivery line, and a processor device configured to derive, from the force measured by the sensor, a pressure value indicative of the pressure in the delivery line and to compare the pressure value to a threshold value for determining whether an occlusion in the delivery line is present. A storage device stores a compliance value associated with the pump and/or the delivery line, and the processor device is configured to compute, from the stored compliance value, the flow rate and the threshold value, an estimate of a duration between the time of an occurrence of an occlusion and the time at which the pressure value exceeds the threshold value.
    Type: Grant
    Filed: July 6, 2016
    Date of Patent: February 15, 2022
    Assignee: Fresenius Vial SAS
    Inventor: Remy Wolff