Patents Examined by Kevin C Sirmons
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Patent number: 11406485Abstract: In vivo positionable filtration devices are provided that filter one or more therapeutic agents in blood flowing in a blood vessel. The filtration devices include an elongated member and a filtering component coupled to the elongated member. The elongated member and the filtering component are dimensioned for positioning within the blood vessel of a human or non-human animal. Further, the filtering component includes a filtration material to filter the one or more therapeutic agents from the blood. Methods of in vivo filtration of the one or more therapeutic agents are also provided. The methods include positioning a filtration device in the blood vessel of a body of the human or non-human animal, and administering a therapeutic agent upstream from a target tissue site to direct flow of the therapeutic agent to the target tissue site and then to the filtration device. The filtration device is positioned downstream from the target tissue site.Type: GrantFiled: December 18, 2013Date of Patent: August 9, 2022Assignee: THE REGENTS OF THE UNIVERSITY OF CALIFORNIAInventors: Steven W. Hetts, Anand S. Patel, Mark W. Wilson
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Patent number: 11406794Abstract: An intravenous (IV) catheter system may include a catheter hub, a needle hub and a needle shield. The needle hub may include a needle having a high friction surface part. Furthermore, embodiments may include an open and closed IV catheter system. Embodiments may include a needle hub and a shielded needle system.Type: GrantFiled: December 30, 2015Date of Patent: August 9, 2022Assignee: Greiner Bio-One GmbHInventor: Magnus Hivert
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Patent number: 11400220Abstract: An active injection guide concurrently monitors surface contact and an instantaneous contact force along an injection axis of an injector in order to ensure that the injector is properly positioned on a patient before an injection can be initiated.Type: GrantFiled: May 1, 2019Date of Patent: August 2, 2022Assignee: Portal Instruments, Inc.Inventors: Robert J. Dyer, Andrew Coats, Patrick Anquetil
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Patent number: 11400207Abstract: A device includes a syringe having a barrel and a syringe tip; an aerator having (i) a generally cylindrical exterior body; (ii) an inlet end; (iii) an outlet end; (iv) a tapered outlet port at its outlet end; and (v) an interior cavity comprising (A) an input port section, (B) a converging section, (C) a throat section, (D) a diverging section, (E) an outlet section, (F) a first vent that fluidly couples at least one of the throat section or the diverging section to an area outside and adjacent to the exterior body, and (G) a second vent that fluidly couples the outlet section to the area; and a housing that (x) circumferentially surrounds an end of the barrel and the aerator, (z) has an interior surface, (aa) forms a circumferential gas pocket between the interior surface and the exterior body, and (bb) has a housing discharge tip.Type: GrantFiled: December 30, 2021Date of Patent: August 2, 2022Assignee: Agitated Solutions Inc.Inventors: Benjamin Arcand, Carl Lance Boling
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Patent number: 11389531Abstract: Methods and apparatus for the reproducible, consistent and efficacious delivery of an HBV vaccine to a subject. The disclosure comprises apparatus for the controlled administration of the HBV vaccine through an orifice to the subject, a plurality of penetrating electrodes arranged with a predetermined spatial relationship relative to the orifice, and an electrical signal generator operatively connected to the electrodes.Type: GrantFiled: December 18, 2018Date of Patent: July 19, 2022Assignees: Janssen Sciences Ireland Unlimited Company, Ichor Medical Systems, Inc.Inventors: Daniel Boden, Helen Horton, Jean-Marc Edmond Fernand Marie Neefs, Soumitra Roy, Andrew W. Hannaman, Robert M. Bernard, Stephen A. Morse, Oliver Ruck, Adam Hartman, Thomas David Cox, Dorien De Pooter
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Patent number: 11389196Abstract: Therapeutics and methods of treatment to repair, preserve and grow cartilage are presented. In addition, systems and methods for delivering a therapeutic to a hard to reach anatomical area, such as, for example, the BCI, are presented. A cannulated delivery device provided with a cutting tip, cutting flutes and threads on its distal end can be provided. Using such an exemplary device, various novel therapies for joint and cartilage repair, preservation and generation can be implemented. The device may have two-needles, with a first cannula/needle, with a finger grip at its distal end, and a longer inner needle to penetrate through the outer needle into the disc, and introduce therapeutics, for example, via a syringe. When provided with a septum at the inner needle's proximal end, the PIARES device is a completely closed system, and its use minimizes trauma.Type: GrantFiled: April 29, 2020Date of Patent: July 19, 2022Inventors: Vijay Vad, Raghav Barve, Paul Mulhauser, Karl D. Kirk, III
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Patent number: 11383032Abstract: A method for performing a continuous infusion process includes delivering a first fluid through a first delivery line at a first flow rate using a first infusion device in a first phase, and delivering a second fluid through a second delivery line at a second flow rate using a second infusion device in a second phase following the first phase. A relay device connected to said first and second delivery lines configured to discharge first or second fluid to an outlet delivery line connected to the relay device, the outlet delivery line having a predefined delivery volume. Subsequent to the delivery of the first fluid in the first phase, the second infusion device in an intermediate phase is operated for a predetermined delivery time to deliver the second fluid at the first flow rate, the predetermined delivery time determined taking the predefined delivery volume into account.Type: GrantFiled: June 13, 2016Date of Patent: July 12, 2022Assignee: Fresenius Vial SASInventors: Maxime Buriat, Alexandre Guerrini
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Patent number: 11369753Abstract: A dual-needle syringe capable of preventing infection, including: an infusion needle shaft (3) configured to aspirate a liquid from a drug container (30); an injection needle shaft (5) having a sharp point of one end inserted into a body, and the other end connected to the syringe (10), through which the liquid filled in the syringe (10) is injected into a body; a hub barrel (7) engaged to a barrel (15) of the syringe (10) to infuse the liquid, which is aspirated from the drug container (30) through the infusion needle shaft (3), into the syringe (10) through the injection needle shaft (5), the hub barrel having an infusion needle shaft hub (21) and an injection needle shaft hub (23) which can be separated from each other before the liquid is injected; and a filter (9) configured to filter foreign substances contained in the liquid.Type: GrantFiled: June 11, 2018Date of Patent: June 28, 2022Inventors: Jong-Eun Park, Ah Ri Song
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Patent number: 11364146Abstract: An ophthalmic device including a cannula having a cannula distal end, a lumen, and one or more orifices coupled to the lumen is provided. The cannula is configured to deliver a fluid. A sleeve is disposed around the cannula and has a sleeve distal end. A handle is coupled to the sleeve and the cannula, the handle having an actuator. An internal mechanism is coupled to the actuator and configured to retract the sleeve relative to the cannula. The internal mechanism includes a follower fixedly coupled to the sleeve and moveable between distal and proximal positions, and a release member movable between an activated position and a release position. The release member is coupled to the actuator and configured to release a force that urges the follower from the distal position to the proximal position when the release member moves from the activated position to the release position.Type: GrantFiled: July 21, 2021Date of Patent: June 21, 2022Assignee: NEW WORLD MEDICAL, INC.Inventors: Malik Y. Kahook, Eric Porteous, Carlos A. Mendoza
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Patent number: 11357918Abstract: A drive assembly for a drug delivery system including a plunger member configured to engage and move a stopper within a container, a biasing member configured to move the plunger member, and an adjustable spacer assembly positioned between the plunger member and the stopper. The spacer assembly includes a spacer element attached to the stopper and at least one shim or includes a spacer element and a holder to which the spacer element is attached. The holder may be attached to the stopper and the spacer element may be attached to the holder by a threaded engagement. Also, a drug delivery system for injecting a medicament, the system including a container configured to receive a medicament, the container comprising a stopper configured to move within the container and a closure, a drive assembly as described above, and a needle actuator assembly.Type: GrantFiled: October 15, 2018Date of Patent: June 14, 2022Assignee: Becton, Dickinson and CompanyInventors: Richard James Vincent Avery, Malcolm Stanley Boyd, Oliver Charles Gazeley, Gareth James Lewis, David Aubrey Plumptre, James Alexander Senior
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Patent number: 11357961Abstract: The invention relates to a connector (1) for connecting a catheter (2) to a fluid transfer system comprising a main body (11) with a tubular pin (111) adapted to be inserted into an end portion (21) of the catheter (2) such as to provide a fluid connection between the catheter (2) and the tubular pin (111). The connector (1) is characterized in that a fixing means (12) is movably connected to the main body (11), wherein the fixing means (11) is adapted to fix the catheter (2) to the connector (1) when the fixing means (12) is in a fixing position.Type: GrantFiled: April 21, 2017Date of Patent: June 14, 2022Assignee: Fresenius Kabl Deutschland GmbHInventor: Barbara Amon
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Patent number: 11351354Abstract: An extension set may include a clamp, which may include a housing and an actuator. The actuator may be movable between a raised position and a depressed position with respect to the housing. The actuator may include a bump profile. The extension set may include an extension tube, which may be disposed within the housing. The extension tube may include a loop. In response to movement of the actuator between the raised position and the depressed position with respect to the housing, the bump profile may progressively clamp the extension tube along the loop. The loop may facilitate an increased fluid volume flowing distally towards a catheter in response to actuating the clamp.Type: GrantFiled: February 18, 2020Date of Patent: June 7, 2022Assignee: Becton, Dickinson and CompanyInventor: Joseph Spataro
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Patent number: 11351328Abstract: A breathing circuit for delivering heated, humidified gases to a patient for medical purposes is described, comprising a humidifier chamber holding a quantity of water, a blower unit that delivers a pressurized gases stream to the chamber inlet, and a control system that adjusts output parameters of the breathing circuit, the circuit including a heater plate which heats the water in the chamber so that gases flowing through the chamber become heated and humidified, the circuit also including a gases transportation pathway and patient interface to convey heated humidified gases to a patient, the gases transportation pathway including an RFID tag located at the patient end which senses a parameter of the gases passing through the pathway, the control system including an RFID interrogator interrogating and receiving data relating to the sensed parameter from the RFID tag in real time, and adjusting the output parameters of the breathing circuit accordingly.Type: GrantFiled: October 10, 2018Date of Patent: June 7, 2022Assignee: Fisher & Paykel Healthcare LimitedInventors: Andrew Robert Donald Somervell, Nordyn Alami, Dexter Chi Lun Cheung, Christopher Simon James Quill, Matthew Jon Payton
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Patent number: 11351343Abstract: The present invention is a simple-to-use IV placement assist device with an added safety feature. A catheter advancer is slidably integrated with a base to guide advancement of a catheter linearly along the insertion path of the needle and catheter. A safety feature is engaged by a movable component moving from a first position to a second position, such movable enabling relative movement between the base and catheter advancer and/or catheter assembly, rotation of the needle about its length axis, and/or minor advancement of the catheter assembly to sheath the tip of the needle. The IV placement assist device stabilizes and guides the critical needle insertion and catheter advancement steps of a complication-prone and very common procedure.Type: GrantFiled: July 19, 2018Date of Patent: June 7, 2022Assignee: INNOVITAL, LLCInventors: Amit Shah, Curt Kothera, Pablo Sztein
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Patent number: 11344314Abstract: Microcatheters and methods for modifying and delivering suspended particles to target bodily parts (e.g., of a cardiovascular system). Embolization microcatheters and uses thereof in performing local embolization procedures, involving modifying flow characteristics (momentum) of suspensions during delivery. Applicable for delivering embolization material in a small blood vessel towards a target bodily part, and for performing local embolizations in small blood vessels feeding (possibly, cancerous) target bodily parts, thereby forming emboli therein, while preventing or minimizing non-target embolization.Type: GrantFiled: March 2, 2016Date of Patent: May 31, 2022Assignee: ACCURATE MEDICAL THERAPEUTICS LTD.Inventors: Michael Gabriel Tal, Eran Miller
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Patent number: 11338095Abstract: The disclosure relates to a drug delivery device, comprising: a housing to receive a cartridge with a needle and a stopper, wherein the cartridge is movable within the housing so as to cover the needle within the housing or advance the needle beyond the housing, a gas tank containing a pressurized gas within the housing, the gas tank connectable with a cavity for moving the cartridge, a cavity for moving the stopper and a cavity for moving the cartridge, a release member fixed to the housing and adapted to restrict movement of the cartridge relative to the housing in a proximal direction, a membrane between the cavity and the retraction release member adapted to operate the release member if the membrane is deformed by a pressure within the cavity exceeding a predetermined value allowing movement of the cartridge relative to the housing in the proximal direction.Type: GrantFiled: July 12, 2017Date of Patent: May 24, 2022Assignee: Sanofi-Aventis Deutschland GMBHInventor: Christian Rehbein
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Patent number: 11331457Abstract: A balloon catheter is disclosed having a balloon at a distal portion of a catheter shaft and on a surface of the balloon are elongate bodies which are crystals of a water-insoluble drug having independent long axes. The balloon in a deflated state has a plurality of wing portions in a circumferential direction of the balloon, and a circumferential surface portion along a circumferential direction of the catheter shaft, the plurality of wing portions being folded along the circumferential direction of the balloon. A surface of the circumferential surface portion which faces the plurality of wing portions that are folded has a region in which tip portions are not in contact with the surface of the balloon or with other elongate bodies, and a surface which faces the plurality of wing portions that are folded which faces an outer circumferential side has a region in which the tip portions are in contact with the surface of the balloon or with the other elongate bodies.Type: GrantFiled: September 20, 2018Date of Patent: May 17, 2022Assignee: TERUMO KABUSHIKI KAISHAInventors: Hiroshi Goto, Katsumi Morimoto, Yasuo Kurosaki
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Patent number: 11324935Abstract: Provided herein is an implant for delivering a hydrophobic active agent to a target tissue. The implant may include a scaffold defining a first surface and a second surface opposite the first surface, wherein the scaffold is substantially impermeable to the hydrophobic active agent, and a silicone tubing having a wall permeable to the hydrophobic active agent, wherein a first length of the silicone tubing is affixed to the first surface of the scaffold, wherein two ends of the silicone tubing extend from the first surface, and wherein a path outlined by a second length of the silicone tubing within the first length is circuitous. Also provided is a method of using the implant to locally deliver the hydrophobic active agent to the target tissue, and kits that find use in performing the present method.Type: GrantFiled: February 12, 2019Date of Patent: May 10, 2022Assignee: The Regents of the University of CaliforniaInventors: Pamela Munster, Jim Kiriakis, Hani Sbitany, Scott Thomas
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Patent number: 11324861Abstract: Syringe plunger rods comprising an elongate body formed from a composition comprising one or more of virgin material, a sterilization-stable recycled resin and a biobased compositions are described. Plunger rods comprising a plurality of ribs, some of which may have a plurality of openings, are also described. The plunger rods requiring less material while maintaining sufficient structural integrity to function properly.Type: GrantFiled: September 28, 2015Date of Patent: May 10, 2022Assignee: Becton, Dickinson and CompanyInventors: Ankur S. Kulshrestha, Yan Yevmenenko, Dinesh S. Kommireddy, Andrew Wong, Behzad Mottahed, Michael V. Quinn, Mildred Calistri-Yeh, Lourdes Pia L. Amora
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Patent number: 11318304Abstract: The present invention provides a system and a method for measuring an impedance of one or more target cells before and after an electroporation protocol has been applied to the one or more target cells. A result of the impedance measurement provides a feedback control that can be implemented during and/or after the electroporation protocol to customize an electrical treatment for a particular target cell or cellular tissue.Type: GrantFiled: September 29, 2017Date of Patent: May 3, 2022Assignee: University of South FloridaInventors: Mark Jeffrey Jaroszeski, Timothy Fawcett, Richard Jason Connolly, Andrew M. Hoff, Reginald Morley Atkins, Douglas Walter Brown, Richard A. Gilbert