Patents Examined by Kiho Kim
  • Patent number: 11692926
    Abstract: In one aspect, the present teachings provide a system for performing cytometry that can be operated in three operational modes. In one operational mode, a fluorescence image of a sample is obtained by exciting one or more fluorophore(s) present in the sample by an excitation beam formed as a superposition of a top-hat-shaped beam with a plurality of beams that are radiofrequency shifted relative to one another. In another operational mode, a sample can be illuminated successively over a time interval by a laser beam at a plurality of excitation frequencies in a scanning fashion. The fluorescence emission from the sample can be detected and analyzed, e.g., to generate a fluorescence image of the sample. In yet another operational mode, the system can be operated to illuminate a plurality of locations of a sample concurrently by a single excitation frequency, which can be generated, e.g., by shifting the central frequency of a laser beam by a radiofrequency.
    Type: Grant
    Filed: May 16, 2022
    Date of Patent: July 4, 2023
    Assignee: BECTON, DICKINSON AND COMPANY
    Inventors: Eric D. Diebold, Keegan Owsley, Jonathan Lin
  • Patent number: 11693131
    Abstract: A radiation imaging apparatus comprising a first scintillator, a second scintillator which receives radiation transmitted through the first scintillator, conversion elements and a controller is provided. The conversion elements include first conversion elements and second conversion elements with different sensitivities for detecting light emitted from at least one of the first scintillator or the second scintillator. During radiation irradiation, the controller obtains, from a signal output from one or more measuring element configured to measure a dose of incident radiation, a first signal corresponding to light converted from radiation by the second scintillator, and outputs, based on the first signal, a stop signal configured to stop the radiation irradiation, and after the radiation irradiation, the controller causes the first conversion elements and the second conversion elements to output signals configured to generate an energy subtraction image.
    Type: Grant
    Filed: November 12, 2021
    Date of Patent: July 4, 2023
    Assignee: CANON KABUSHIKI KAISHA
    Inventors: Jun Kawanabe, Kentaro Fujiyoshi
  • Patent number: 11692935
    Abstract: Disclosed is a transient-state THz spectrometer applied to cells and biological macromolecules, including a femtosecond laser amplifier. A femtosecond laser output by the femtosecond laser amplifier is divided into two beams of pump light and probe light after passing through a beam splitter of which a transmission-reflection ratio is 7:3, the pump light is focused to irradiate a gap between electrodes of a nonlinear photoconductive antenna and emit a terahertz wave after successively passing through a half wave plate, a silver-plated reflector and a first lens, the terahertz wave forms a terahertz wave collineation after successively passing through a second lens, a slab waveguide, a third lens and an ITO film, the terahertz wave collineation and the probe light form a probe light collineation of wavefront tilt which is perpendicularly incident on a ZnTe crystal and detected and recorded by using a CCD camera.
    Type: Grant
    Filed: January 13, 2021
    Date of Patent: July 4, 2023
    Assignee: XI'AN UNIVERSITY OF TECHNOLOGY
    Inventors: Wei Shi, Lei Hou, Cheng Ma, Chengang Dong, Lei Yang, Jiaguang Han, Yanfeng Li, Chunmei Ouyang, Jianqiang Gu, Liguo Zhu, Zhaohui Zhai, Lianghui Du, Yi Zou
  • Patent number: 11693012
    Abstract: A screening method is provided. Cells secreting target antibodies are screened by mixing candidate cells labeled with a first fluorescent molecule, a capture antigen and a labeled antibody against a target antibody and incubating, labeling using a high content cell imager and sorting using flow cytometry so as to screen cells secreting target antibodies. The screening method disclosed in the present application can automatically complete the labeling and sorting of target candidate cells in high throughput by labeling with a fluorescent molecule in combination with high-content cell imager and flow cytometer, so as to provide sufficient quantity of cells for subsequent amplification to obtain their antibody sequences and screen affinity antibodies. This method greatly improves the screening efficiency.
    Type: Grant
    Filed: February 26, 2021
    Date of Patent: July 4, 2023
    Assignee: SUZHOU INSTITUTE OF NANO-TECH AND NANO-BIONICS (SINANO) , CHINESE ACADEMY OF SCIENCES
    Inventors: Kefeng Pu, Jiong Li, Min Jiang
  • Patent number: 11693132
    Abstract: A scintillator attachment structure includes an opening formed in a first side wall portion of a housing and a scintillator holder that holds the scintillator and includes a holder portion fitted in the opening. The scintillator holder can be attached to and detached from the housing. While the scintillator holder is attached to the housing, a predetermined angle is formed between the scintillator held by the holder portion protruding from the first side wall portion into the housing and the front surface mirror in the housing.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: July 4, 2023
    Assignee: HAMAMATSU PHOTONICS K.K.
    Inventor: Mototsugu Sugiyama
  • Patent number: 11686674
    Abstract: The present invention is directed to a gas detector configured to improve response speed of a gas sensor. A gas detector includes a housing, a gas sensor main body installed in the housing, and a partition wall provided in the housing and limiting the surrounding of the gas sensor main body to separate from the other area. The housing or the partition wall includes an opening portion directly connected from the outside to an area inside the partition wall.
    Type: Grant
    Filed: July 27, 2021
    Date of Patent: June 27, 2023
    Assignee: Asahi Kasei Microdevices Corporation
    Inventors: Maksym Bryzgalov, Mats Olsson, Henrik Rodjegard, Hans Martin
  • Patent number: 11681058
    Abstract: According to one embodiment, a radiation detector includes first and second resin members, a detection part, a wiring part, and a controller. The first resin member includes first and second partial regions, and a third partial region between the first and second partial regions. The second resin member includes fourth and fifth partial regions. The detection part is provided between the first and fourth partial regions. The detection part includes a first conductive layer, a second conductive layer provided between the first conductive layer and the fourth partial region, and an organic semiconductor layer provided between the first and second conductive layers. The wiring part is provided between the third and fifth partial regions. The wiring part includes first and second wiring layers. The controller is fixed to the second partial region. The controller is electrically connected with the first and second wiring layers.
    Type: Grant
    Filed: February 11, 2022
    Date of Patent: June 20, 2023
    Assignee: KABUSHIKI KAISHA TOSHIBA
    Inventors: Isao Takasu, Atsushi Wada, Kohei Nakayama, Yuko Nomura, Fumihiko Aiga
  • Patent number: 11681055
    Abstract: A radiation detector includes a photodetector and a scintillator coupled thereto. The scintillator is formed of a scintillator material comprising an organic glass scintillator (OGS) material and at least one of a polymer additive or a plasticizer additive. The scintillator emits light when radiation is received at the scintillator, and the light is received by the photodetector. The radiation detector can further include a frame that has an interior cavity that holds the scintillator in position with respect to the photodetector, such that the light emitted by the scintillator is transmitted to the photodetector. The scintillator can be formed by casting amorphous scintillator material in the interior cavity of the frame. The frame can then be coupled to the photodetector to form the radiation detector.
    Type: Grant
    Filed: January 26, 2021
    Date of Patent: June 20, 2023
    Assignee: National Technology & Engineering Solutions of Sandia, LLC
    Inventors: Joseph Carlson, Patrick L. Feng, Nicholas Myllenbeck, Huu Tran, Lucas Nguyen, Melinda Sweany, Peter Marleau
  • Patent number: 11680852
    Abstract: A temperature measurement system includes a thermal camera configured to capture a thermal image of individuals in a viewing space of the thermal camera to detect temperatures of the individuals. A reference device is configured to present a reference temperature for detection by the thermal camera when the reference device is disposed in the viewing space of the thermal camera. The reference device is configured to maintain thermal stability in harsh or hazardous environments so that the system provides accurate and precise temperature detection of the individuals in the viewing space of the thermal camera.
    Type: Grant
    Filed: May 21, 2021
    Date of Patent: June 20, 2023
    Assignee: EATON INTELLIGENT POWER LIMITED
    Inventors: Christopher Ring, Jon C. Beaver, Stewart John Parfitt
  • Patent number: 11678856
    Abstract: Systems and methods for providing a real time visualization of scattered radiation in a medical facility are provided. A number of visualization devices such as augmented reality (“AR”) tracking devices, electronic displays, or projection devices are in electronic communication with a controller and configured to generate a visualization of scattered radiation. Position data is received from the position sensors associated with individuals in the medical facility, the AR tracking devices, radiation producing medical equipment, or radiation scattering medical equipment, and the visualization is adjusted accordingly.
    Type: Grant
    Filed: June 20, 2022
    Date of Patent: June 20, 2023
    Inventor: John Pigott
  • Patent number: 11675093
    Abstract: The present invention relates to an apparatus for determining the location of a radiation source. The apparatus for determining the location of a radiation source according to the present invention comprises: a collimator part for selectively passing radiation therethrough according to the direction in which the radiation is incident; a scintillator part for converting the radiation incident from the collimator part into a light ray; a first optical sensor for converting the light ray incident from one end of the scintillator part into a first optical signal; a second optical sensor for converting the light ray incident from the other end of the scintillator part into a second optical signal; and a location information acquisition part for acquiring information on the location where the light ray is generated in the scintillator part, by using the second optical signal and the second optical signal.
    Type: Grant
    Filed: December 18, 2019
    Date of Patent: June 13, 2023
    Assignees: Korea University Research and Business Foundation, Korea Atomic Energy Research Institute
    Inventors: Jung-Yeol Yeom, Seop Hur, Inyong Kwon, Chanho Kim
  • Patent number: 11675094
    Abstract: An X-ray device is provided, which includes a flexible substrate, a driver integrated circuit, and a scintillator layer. The flexible substrate includes an array portion and an extension portion. The driver integrated circuit is disposed on the flexible substrate. The scintillator layer is disposed on the flexible substrate.
    Type: Grant
    Filed: August 12, 2021
    Date of Patent: June 13, 2023
    Assignee: InnoCare Optoelectronics Corporation
    Inventors: Wen Chien Lin, Chih-Hao Wu
  • Patent number: 11666293
    Abstract: Extended field-of-view imaging is enabled by combined imaging with a kilovolt (“kV”) x-ray source and a megavolt (“MV”) x-ray source, in which at least one of the corresponding x-ray detectors is laterally offset from the target isocenter by an amount such that the x-ray detector does not have a view of the target isocenter. This scan geometry enables the reconstruction of non-truncated images without resorting to the more expensive solution of outfitting the imaging or radiotherapy system with enlarged x-ray detectors.
    Type: Grant
    Filed: July 6, 2021
    Date of Patent: June 6, 2023
    Assignees: THE BRIGHAM AND WOMEN'S HOSPITAL, INC., DANA-FARBER CANCER INSTITUTE, INC.
    Inventors: Matthew Jacobson, Ross Berbeco
  • Patent number: 11662486
    Abstract: According to an example aspect of the present invention, there is provided a radiation window manufacturing method, comprising patterning a mask on a top surface of a bulk wafer or compound wafer, etching the bulk or compound wafer from the top surface, based on the mask, either by timed etching of the bulk wafer, or until an inner insulator layer of the compound wafer, thereby generating recesses in the bulk or compound wafer, filling the recesses, at least partly, with a filling material, polishing the top surface of the bulk or compound wafer, and providing a membrane layer on the polished top surface, and etching the bulk or compound wafer from a bottom surface, opposite the top surface, to build a supporting structure for the membrane layer in accordance with a shape defined by the mask.
    Type: Grant
    Filed: March 17, 2020
    Date of Patent: May 30, 2023
    Assignee: Oxford Instruments Technologies Oy
    Inventors: Zhengjung Liu, Nikolai Chekurov
  • Patent number: 11650338
    Abstract: The scintillation detector assembly 10 comprises a first scintillation detector 11A of a set SSD of scintillation detectors 11, comprising a first scintillator 12A of a set SS of scintillators 12 and a first light sensor 13A of a set SLS of respective light sensors 13 optically coupled thereto, arranged to detect electromagnetic radiation and output a first signal; a first radiation source 14A of a set SRS of radiation sources 14, configured to emit first gamma radiation G1 of a first set SG of gamma radiation G, having a first reference energy RE1 of a set SRE of respective first reference energies RE; and a controller 15 configured to control a gain of the first scintillation detector 11A based, at least in part, on the first gamma radiation, having the first reference energy, detected by the first scintillation detector 11A.
    Type: Grant
    Filed: November 20, 2019
    Date of Patent: May 16, 2023
    Assignee: BAE SYSTEMS PLC
    Inventor: Lionel William John Kent
  • Patent number: 11644580
    Abstract: A method for radiation dosage measurement includes: (1) exposing a plurality of single-poly floating gate sensor cells to radiation; (2) measuring threshold voltage differences between logical pairs of the exposed sensor cells using differential read operations, wherein the sensor cells of each logical pair are separated by a distance large enough that radiation impinging on one of the sensor cells does not influence the other sensor cell; (3) determining whether each logical pair of exposed sensor cells is influenced by exposure to the radiation in response to the corresponding measured threshold voltage difference; and (4) determining a dosage of the radiation in response to the number of logical pairs of the exposed sensor cells determined to be influenced by exposure to the radiation. A non-radiation influenced threshold voltage shift may be measured and used in determining whether each logical pair of exposed sensor cells is influenced by radiation exposure.
    Type: Grant
    Filed: April 14, 2022
    Date of Patent: May 9, 2023
    Assignee: Tower Semiconductor Ltd.
    Inventors: Yakov Roizin, Evgeny Pikhay, Vladislav Dayan
  • Patent number: 11644903
    Abstract: A method in an electronic device, the method includes projecting infrared (“IR”) light from a plurality of light emitting diodes (“LEDs”) disposed proximate to the perimeter of the electronic device, detecting, by a sensor, IR light originating from at least two of the plurality of LEDs reflected from off of a person, and carrying out a function based on the relative strength of the detected IR light from the LEDs.
    Type: Grant
    Filed: July 12, 2021
    Date of Patent: May 9, 2023
    Assignee: Google Technology Holdings LLC
    Inventors: Rachid Mohsen Alameh, Patrick J. Cauwels, Kenneth A. Paitl
  • Patent number: 11644364
    Abstract: A thermopile sensor including a uniform substrate having a first surface with a first section and a second section at an elevation varying relative to the first section by between about 5 micrometers and about 500 micrometers. The sensor further includes a plurality of thermopile junctions, with each junction having (i) a first strip of a first conductive material, extending from the first section to the second section, (ii) a second strip of a second conductive material, forming an electrical junction with the first strip on the second section and extending to the first section, and (iii) with the thermopile junctions being connected in series. A first contact pad on the substrate is connected to an initial thermopile junction and a second contact pad on the substrate is connected to a last thermopile junction, with conductors connecting to the first and second contact pads and extending off of the substrate.
    Type: Grant
    Filed: July 18, 2019
    Date of Patent: May 9, 2023
    Assignee: Louisiana Tech Research Corporation
    Inventor: Arden Moore
  • Patent number: 11635533
    Abstract: A three-dimensional part intended to cooperate with: a single-piece base comprising a first main face, a second main face, the base being delimited by four lateral faces, the base being able to support a digital detector on the first main face and an electronic circuit board, a mechanical protection housing, the base, the digital detector and the electronic circuit board being intended to be arranged in the mechanical protection housing, the housing comprising four lateral faces, a top face and a bottom face; the three-dimensional part being comprising a bottom part linked to the base and at least partially enclosing a lateral face of the base; a top part extending from the first main face of the base to the top face of the housing.
    Type: Grant
    Filed: February 7, 2022
    Date of Patent: April 25, 2023
    Assignee: TRIXELL
    Inventors: Sylvain Pons, Pierre Rieuvernet
  • Patent number: 11635530
    Abstract: An X-ray sensing device includes a photosensitive element, lead-containing glass, and an X-ray conversion structure. The photosensitive element is configured to sense light having a first wavelength. The lead-containing glass overlaps the photosensitive element. The X-ray conversion structure is disposed on the lead-containing glass. The lead-containing glass is located between the photosensitive element and the X-ray conversion structure. The X-ray conversion structure is configured to at least partially convert X-rays into light having the first wavelength.
    Type: Grant
    Filed: October 27, 2021
    Date of Patent: April 25, 2023
    Assignee: Au Optronics Corporation
    Inventors: Chia-Hsiu Tsai, Chia-Ming Chang, Ruei-Pei Chen