Abstract: The invention relates to a system for determining a radiation therapy plan for a radiation therapy system (100), comprising a multi-leaf collimator. The radiation therapy plan determination system (110) comprises a therapy system characteristics providing unit (111), wherein the characteristics comprise possible leaf positions and possible radiation fluence values, a planning objectives providing unit (112), wherein the planning objectives are indicative of a desired therapeutic radiation dose distribution, an optimization function providing unit (113), wherein the optimization function is indicative of a deviation of a radiation dose distribution from the planning objectives and of an uncertainty of the radiation dose distribution at edges of the possible apertures, and a therapy plan optimization unit (114) adapted to determine a sequence of possible apertures and possible radiation fluence values for which the optimization function is optimized.

Abstract: A method of measuring an environmental contaminant includes the steps of dividing a target environment into a plurality of spaces, placing a monitor in each space, uploading device data from each monitor, and processing the device data to determine a level of environmental contamination within each space. Each monitor is configured to measure a level of an environmental contaminant within the space for a sample period. A radon monitor includes a radon sensor configured to detect radon decay events, an environmental sensor configured to measure an ambient condition of air surrounding the radon sensor, a processor configured to record device data including a count of a number of radon decay events and the ambient conditions, and a communication means for transmitting the device data. A system includes a plurality of monitors, a receiving device for receive device data from each monitor, and a cloud computer to process the device data.

Abstract: Methods for imaging a sample using fluorescence microscopy, systems for imaging a sample using fluorescence microscopy, and illumination systems for fluorescence microscopes. In some examples, a method includes positioning the sample such that a plane of interest of the sample is coplanar with a focal plane of a detection objective of a microscope; positioning a mirror around the sample; directing a beam of annularly collimated excitation light on the mirror to focus a disc of light on the sample; and imaging the sample through the detection objective.

Abstract: A heterogeneous patient-based breast phantom that mimics the anatomy and properties of real breast tissues when screened with ionizing and nonionizing imaging modalities is described. The heterogeneous breast phantom includes a skin mimicking segment; an adipose tissue mimicking segment; a fibro-glandular tissue mimicking segment; and a pectoral muscle mimicking segment wherein each segment is shaped and arranged such that the breast phantom represents a breast tissue. Performance of the breast phantom was characterized by mass attenuation coefficient, electron density and effective atomic number. Further, performance of breast phantoms was confirmed CT and breast MRI machines.

Abstract: The present invention relates to spectral correction. A spectral correction apparatus is described that is configured to identify a voltage fluctuation in the X-ray tube and to parameterize the high voltage fluctuation to correct the effective X-ray spectrum per individual frame.

Abstract: Methods and apparatus for determining a parameter of a structure fabricated in or on a substrate and compensated for a drift error. The methods comprising: illuminating, at a plurality of times, at least part of the structure with electromagnetic radiation, the at least part of the structure being at a first orientation; sensing, at the plurality of times, a plurality of average reflectances of the at least part of the structure; and determining, based on the plurality of average reflectances, an estimation of the parameter at one or more further times.

Abstract: A security device, such as a passive infra-red motion detector (1) is provided with a plurality of fasteners (15, 25). One fastener (25) removably fastens a lens (4) to a housing of the passive infra-red detector, such that the lens (4) can be removed from the outside of the housing, whilst the other fastener (15) fastens a front section (2) of the housing to the rear section (3). Both fasteners (15, 25) are transparent/translucent and act as light guides.

Abstract: A gantry cooling system of a diagnostic medical imaging apparatus transfers apparatus-generated heat, such as gantry heat, to a solid material heatsink, via a circulating-fluid coolant conduit. In some embodiments, the heatsink is incorporated in the ground or within the building structure housing the apparatus.

Abstract: The present disclosure is related to systems and methods for radiation. The method may include obtaining a plurality of reference images of a target of a subject and reference physiological motion information of the subject. The plurality of reference images and the reference physiological motion information may be acquired in a radiation period. The method may include establishing a correlation model based on the plurality of reference images and the reference physiological motion information. The method may include monitoring real-time motion information of the target based on the correlation model during a radiation operation performed during the radiation period.

Abstract: A method is provided for determining a scatter fraction for a radiation diagnosis apparatus. The method includes acquiring an energy spectrum from list mode data obtained from a scan performed using the radiation diagnosis apparatus; determining, from the acquired list mode data, a first number of events occurring in a first energy window spanning a first energy range; determining, from the acquired list mode data, a second number of events occurring in a second window, the second energy window spanning a second energy range different from the first energy range; calculating a singles scatter fraction based on the determined first number of events and the determined second number of events; and reconstructing an image based on the acquired list mode data and the calculated singles scatter fraction.

Abstract: The present disclosure provides a detection substrate, including: a base substrate, detection pixel units arranged in an array on the base substrate, where each detection pixel unit includes: a thin film transistor and a photoelectric conversion part located on a side of the thin film transistor, and a bias voltage line is arranged on a side of the photoelectric conversion part. The thin film transistor includes: an active layer, a first electrode and a second electrode, and the active layer including a channel region. At least one dielectric layer is provided between the photoelectric conversion part and the bias voltage line, and is formed with a first via hole therein, and at least part of an orthographic projection of the channel region on the base substrate is located within an orthographic projection of the first via hole on the base substrate. A flat panel detector is further provided.

Abstract: A computed tomography (CT) scanning apparatus that includes a set of X-ray sources and a set of flat panel detectors with a set of source collimators and a set of detector collimators therebetween. The design of the openings of the set of detector collimators is such that the images received by the set of flat panel detectors may be combined, or stitched together to generate a single X-ray image.

Abstract: A control method for positioning is provided, which is applicable to a radiotherapy system. The method includes: acquiring a plurality of first body surface coordinates of a target site in a three-dimensional body surface image of a treatment object on a treatment couch; acquiring a plurality of second body surface coordinates under an isocentric coordinate system by transforming the first body surface coordinates using a target transformation matrix corresponding to the first placement position; determining, based on the plurality of second body surface coordinates and a contour image of the target site in the treatment plan, a placement offset of the target site, so as to control the treatment couch to move until the placement offset of the target site upon the movement meets a target offset requirement.

Abstract: A laser scanning microscope includes a light source configured to emit an illumination light beam. The illumination light beam has a transverse light intensity profile comprising an intensity minimum. The laser scanning microscope further includes a scanning device configured to scan the illumination light beam along a closed trajectory in a target area of a specimen, and a detector configured to detect fluorescence light emitted by a fluorophore within the target area of the specimen. The fluorophore is excited by the illumination light beam. The laser scanning microscope further includes a processor configured to determine an intensity distribution of the fluorescence light as a function of time and to determine a position of the fluorophore within the target area based on the intensity distribution of the fluorescence light.

Abstract: The present invention relates to roadside analyzer for determination of illegal drugs abuse, including, but not limiting to detection of explosives, toxic industrial chemicals and other banned or regulated compounds, biomarkers and phytochemicals in a sample in situ in at least one human body fluid sample, specifically in oral fluid (saliva), but not limiting to other clinical samples of interest (urine, blood, exhaled breath, exhaled breath condensate, etc.) It consists of automatic processor for preparing samples suitable for analysis. Analysis part of the instrument implements three technologies, namely solid phase extraction prior to analysis, capillary electrophoresis for separation of analytes from the sample matrix and impedance (contactless conductivity) or fluorescence or both impedance (contactless conductivity) and fluorescence for detection of analytes of interest.

Abstract: A photon counting computed tomography (CT) method including receiving a first forward model including a set of first parameters and a set of second parameters corresponding to a plurality of materials and path lengths by scanning a slab at plural tube voltages and plural tube currents of an X-ray tube; evaluating an image quality of a material decomposition image reconstructed by the set of first parameters and the set of second parameters; and updating at least one second parameters from the set of second parameters if the image quality of the material decomposition image does not satisfy a predetermined threshold, wherein the updating is achieved by updating the at least one second parameter from the set of second parameters to an energy dependent parameter from a constant value.

Abstract: A radiation detector includes a photodetector and a scintillator coupled thereto. The scintillator is formed of a scintillator material comprising an organic glass scintillator (OGS) material and at least one of a polymer additive or a plasticizer additive. The scintillator emits light when radiation is received at the scintillator, and the light is received by the photodetector. The radiation detector can further include a frame that has an interior cavity that holds the scintillator in position with respect to the photodetector, such that the light emitted by the scintillator is transmitted to the photodetector. The scintillator can be formed by casting amorphous scintillator material in the interior cavity of the frame. The frame can then be coupled to the photodetector to form the radiation detector.

Abstract: The present document relates to providing a radiation treatment plan for treatment of a neoplasm, including the steps of: obtaining an image including the neoplasm and obtaining first segmentation data for segmenting at least one target-volume to be targeted with radiation. Further identifying any organs-at-risk and segmenting these. The method further comprises identifying lymphocyte-rich-organs in the image, and obtaining third segmentation data for segmenting the lymphocyte-rich-organs. The planning system then obtains radiation dose regime data, including first, second and third dose regime data.

Abstract: An infrared detector with a multi-layer structure based on a CMOS process. A CMOS measuring circuit system and a CMOS infrared sensing structure in the infrared detector are both fabricated by using the CMOS process, and a CMOS manufacturing process comprises a metal interconnection process, a through hole process, an IMD process and an RDL process. In the infrared detector with the multi-layer structure, a first columnar structure comprises at least one layer of solid columnar structure and/or at least one layer of hollow columnar structure, a second columnar structure comprises at least one layer of solid columnar structure and/or at least one layer of hollow columnar structure, at least one hole-shaped structure is formed in an absorption plate, and the hole-shaped structure at least penetrates a dielectric layer in the absorption plate; and/or, at least one hole-shaped structure is formed in a beam structure.

Abstract: A heterogeneous patient-based breast phantom that mimics the anatomy and properties of real breast tissues when screened with ionizing and nonionizing imaging modalities is described. The heterogeneous breast phantom includes a skin mimicking segment; an adipose tissue mimicking segment; a fibro-glandular tissue mimicking segment; and a pectoral muscle mimicking segment wherein each segment is shaped and arranged such that the breast phantom represents a breast tissue. Performance of the breast phantom was characterized by mass attenuation coefficient, electron density and effective atomic number. Further, performance of breast phantoms was confirmed CT and breast MRI machines.