Patents Examined by L. Anderson
  • Dressing
    Patent number: 11666680
    Abstract: A dressing includes a drape, a pressure-sensitive acrylic-based adhesive on a skin-facing surface of the drape, an island of absorbent material, a silicone gel backing film, and a silicone gel on the silicone gel backing film. The drape is a thin film capable of maintaining a negative pressure underneath the drape upon application of a vacuum. The island of absorbent material has a smaller area than the drape and is applied onto the skin-facing surface of the drape. The silicone gel backing film has a frame shape and a smaller footprint than the drape and a larger footprint than the island of absorbent material.
    Type: Grant
    Filed: February 22, 2021
    Date of Patent: June 6, 2023
    Assignee: AATRU MEDICAL, LLC
    Inventors: John Buan, Richard L. Middaugh, Timothy Wojciechowski, Thomas E. Lash
  • Medical systems, devices, and related methods
    Patent number: 11666490
    Abstract: In one example, a medical system may comprise a delivery tube configured to couple to a vacuum source and provide negative pressure to a distal portion of the delivery tube; and a porous body at a distal portion of the delivery tube, the porous body including a first section and a second section removable from the first section.
    Type: Grant
    Filed: February 25, 2021
    Date of Patent: June 6, 2023
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: Ryan V. Wales, Kira Sullivan, Shawn Ryan, Jessica Louise Powers, Joseph W. King
  • Pump device, comprising a pump and a housing accommodating the pump
    Patent number: 11666688
    Abstract: A pump device as may be used in a breast pump assembly including a pump configured to put fluid in motion, a housing accommodating the pump, at least one fluid transporting conduit connected to the pump, the at least one conduit extending between the pump and the housing, thereby connecting the pump to a position at the housing where the housing is provided with at least one opening for allowing fluid to pass, and a mounting arrangement for mounting the pump in the housing. The at least one conduit is part of the mounting arrangement and has flexible properties to reduce an extent to which vibrations of the pump are transferred to the housing through the mounting arrangement during operation of the device.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: June 6, 2023
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Johannes Petrus Antonius Maria Van Asseldonk, Alexander Van Rooijen, Eyob Atnafu Amra
  • Tetrazole derivatives as TRPA1 inhibitors
    Patent number: 11661427
    Abstract: The present disclosure provides certain tetrazole derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing the same.
    Type: Grant
    Filed: October 13, 2021
    Date of Patent: May 30, 2023
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Martin Thomas Fleck, Florian Paul Christian Binder, Jens Willwacher
  • Tetrazole derivatives as TRPA1 inhibitors
    Patent number: 11661430
    Abstract: The present disclosure provides certain tetrazole derivatives that are inhibitors of transient receptor potential ankyrin 1 (TRPA1), and are therefore useful for the treatment of diseases treatable by inhibition of TRPA1. Also provided are pharmaceutical compositions containing the same, and processes for preparing the same.
    Type: Grant
    Filed: October 13, 2021
    Date of Patent: May 30, 2023
    Assignee: Boehringer Ingelheim International GmbH
    Inventors: Florian Paul Christian Binder, Thomas Martin Fleck, Jens Willwacher
  • Processes for making a solid-state form of relugolix
    Patent number: 11655256
    Abstract: The present invention is directed to processes for making an anhydrous form of relugolix, designated herein as Form T of anhydrous relugolix. The processes of making Form T of anhydrous relugolix are from the following: (i) Form A of the DMF solvate of relugolix; (ii) Form B of anhydrous relugolix; or (iii) amorphous relugolix.
    Type: Grant
    Filed: November 6, 2021
    Date of Patent: May 23, 2023
    Assignee: Macfarlan Smith Limited
    Inventor: Nicholas Paschalides
  • Cyclopropylamine compound as LSD1 inhibitor and use thereof
    Patent number: 11649245
    Abstract: Provided is a cyclopropylamine compound as lysine-specific demethylase 1 (LSD1) inhibitor, and a use thereof in preparation of drug for treating diseases associated with LSD1. The cyclopropylamine compound is a compound represented by formula (I), an isomer thereof, and a pharmaceutically acceptable salt thereof.
    Type: Grant
    Filed: September 12, 2019
    Date of Patent: May 16, 2023
    Assignees: HELIOEAST PHARMACEUTICAL CO., LTD., Helioeast Science & Technology Co., Ltd.
    Inventors: Lingyun Wu, Qiuyan Wang, Jian Li, Shuhui Chen
  • Allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) for the treatment of disease
    Patent number: 11649227
    Abstract: The disclosure relates to compounds of Formula (I) as allosteric chromenone inhibitors of phosphoinositide 3-kinase (PI3K) useful in the treatment of diseases or disorders associated with PI3K modulation, Formula (I): or a prodrug, solvate, enantiomer, stereoisomer, tautomer, or pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R6, R7, R8, R9, W, X, Y, s, and Ring A are as described herein.
    Type: Grant
    Filed: April 2, 2021
    Date of Patent: May 16, 2023
    Assignee: Petra Pharma Corporation
    Inventors: Erin Danielle Anderson, Sean Douglas Aronow, Nicholas A. Boyles, Markus K. Dahlgren, Shulu Feng, Aleksey I. Gerasyuto, Eugene R. Hickey, Thomas Combs Irvin, Edward A. Kesicki, Anke Klippel-Giese, Jennifer Lynn Knight, Gabrielle R. Kolakowski, Manoj Kumar, Katelyn Frances Long, Christopher Glenn Mayne, David L. McElligott, Johnathan Alexander McLean, Loredana Puca, Kannan Karukurichi Ravi, Daniel Lee Severance, Michael Brian Welch, Tien Widjaja
  • Pyrazolochlorophenyl compounds, compositions and methods of use thereof
    Patent number: 11649241
    Abstract: Compounds of Formula I and methods of use as Janus kinase inhibitors are described herein.
    Type: Grant
    Filed: February 12, 2021
    Date of Patent: May 16, 2023
    Assignee: Genentech, Inc.
    Inventors: Mark Zak, F. Anthony Romero, Po-wai Yuen, Emily J. Hanan
  • Method for synthesizing diaza-bridged compound and a diaza-bridged compound
    Patent number: 11649244
    Abstract: The present disclosure discloses a method for synthesizing a diaza-bridged compound and a diaza-bridged compound, belonging to the field of organic synthesis. The present disclosure includes the following reaction: in the formula, R is aryl, substituted aryl, alkyl or haloalkyl, Ra is any one of H, 2-nitrobenzenesulfonyl, 4-nitrobenzenesulfonyl or 2,4-dinitrobenzenesulfonyl, n=1 or 2. Since compound 2 and NH3 are used as raw materials, the present disclosure can not only effectively shorten the process flow and save process costs, but also improve the reaction yield to a certain extent. The present disclosure also provides a diaza-bridged compound, where the structural formula thereof is in the formula, Ra is any one of 2-nitrobenzenesulfonyl, 4-nitrobenzenesulfonyl or 2,4-dinitrobenzenesulfonyl.
    Type: Grant
    Filed: December 29, 2021
    Date of Patent: May 16, 2023
    Assignee: LINKCHEM CO., LTD., SHANGHAI
    Inventors: Xi Lu, Shuai Liu, Yong Liang, Jiaming Cai, Quan Tang, Yuan Zeng
  • Functionalised cyclic dithiocarbamate synthesis method
    Patent number: 11643673
    Abstract: Provided is a process for synthesizing a functionalized cyclic dithiocarbamate.
    Type: Grant
    Filed: December 21, 2017
    Date of Patent: May 9, 2023
    Assignee: Arkema France
    Inventors: Georges Fremy, Arnaud Masselin
  • Synthesis of N,N-dimethyltryptamine-type compounds, methods, and uses
    Patent number: 11643390
    Abstract: Syntheses of compounds of Formula III from compounds of Formula I via compounds of Formula II are described, as well as particular compounds of Formula III, or pharmaceutically acceptable salts thereof, compositions comprising such compounds, and uses thereof. For example, certain of these compounds and compositions of Formula III have uses in the treatment of psychiatric or neurological disorders.
    Type: Grant
    Filed: August 26, 2021
    Date of Patent: May 9, 2023
    Assignee: Small Pharma Ltd
    Inventors: Peter Rands, George Knight, Richard Chubb, Derek Londesbrough, Tiffanie Benway, Zelah Joel
  • Renewable highly biobased polybenzoxazine thermosets for composite applications
    Patent number: 11643406
    Abstract: Benzoxazine compounds, methods of making them, polymers made therefrom and methods of polymerizing the benzoxazines. These renewable benzoxazine monomers and polymers that utilize the variety of building blocks found in renewable plant biomass, demonstrate excellent processability and large temperature windows for processing of resin systems.
    Type: Grant
    Filed: August 21, 2018
    Date of Patent: May 9, 2023
    Assignees: Drexel University, The Government of the United States of America, as represented by The Secretary of the Army
    Inventors: Giuseppe R. Palmese, Santosh K. Yadav, John J. LaScala
  • Prodrugs and conjugates of dimethyltryptamine
    Patent number: 11643391
    Abstract: Provided herein are compounds of Formula (I), or pharmaceutically acceptable salt thereof, wherein R1, R2, R3, R4, R5, R8, R9, X, Y, Z, W, and m are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) or pharmaceutically acceptable salt thereof and a pharmaceutically acceptable excipient.
    Type: Grant
    Filed: August 16, 2022
    Date of Patent: May 9, 2023
    Inventors: Robert B. Perni, Glenn Short, Srinivas G. Rao, Tanweer A. Khan
  • Bicyclic heterocycle compounds and their uses in therapy
    Patent number: 11643410
    Abstract: The invention relates to new bicyclic heterocycle compounds, to pharmaceutical compositions comprising the compounds and to the use of the compounds in the treatment of diseases, e.g. cancer.
    Type: Grant
    Filed: December 7, 2021
    Date of Patent: May 9, 2023
    Assignee: ASTEX THERAPEUTICS LIMITED
    Inventors: Gianni Chessari, Christopher Norbert Johnson, Steven Howard, James Edward Harvey Day, Ildiko Maria Buck, Charlotte Mary Griffiths-Jones, Gordon Saxty, Emiliano Tamanini, Nicola Elizabeth Wilsher
  • Strand-based laminates in absorbent articles
    Patent number: 11633309
    Abstract: Absorbent articles comprising a multilayer outer cover comprising a first outer layer and a second outer layer comprising a component that exhibits at least partial elastic recovery after mechanical activation in the machine direction; an inner layer, disposed between the first outer layer and the second outer layer, the inner layer comprising elastic strands; and wherein at least one of the first outer layer and second outer layer is laminated to the inner layer.
    Type: Grant
    Filed: October 23, 2019
    Date of Patent: April 25, 2023
    Assignee: The Procter & Gamble Company
    Inventors: Jean-Philippe Marie Autran, Urmish Popatlal Dalal
  • Wound dressing comprising a monitor interface
    Patent number: 11633304
    Abstract: A wound dressing and a monitor device is disclosed, the wound dressing comprising a top layer; a first adhesive layer with a proximal surface configured for attachment of the wound dressing to the skin surface of a user; an absorbent core layer; an electrode assembly comprising a plurality of electrodes arranged on a distal side of the absorbent core layer; and a monitor interface configured for connecting the wound dressing to a monitor device, the monitor interface comprising a plurality of terminals configured to form electrical connections with respective terminals of the monitor device, wherein the wound dressing comprises a flexible element, the flexible element being bendable and/or twistable between a first flexible element end and a second flexible element end, and wherein the monitor interface comprises a coupling part positioned at the first flexible element end.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: April 25, 2023
    Assignee: Coloplast A/S
    Inventors: Jais Ask Hansen, Lars Erup Larsen, Niels Hvid, Mads Hindhede Svanegaard, Stephanie Knoedler
  • Absorbent component
    Patent number: 11633306
    Abstract: The present invention generally relates to an absorbent component (100) for use in a garment. The absorbent component (100) comprises: a first layer composite (120) comprising a first foam layer (122) and a first liquid impermeable layer (124); an absorbent layer composite (140) bonded to the first liquid impermeable layer (124) for absorbing bodily fluids; and a second liquid impermeable layer (164) bonded to the absorbent layer composite (140) and first layer composite (120) to contain the bodily fluids absorbed by the absorbent layer composite (140), wherein the second liquid impermeable layer (164) forms an opening (166) for receiving the bodily fluids to the absorbent layer composite (140); and wherein the first foam layer (122) is moulded to shape the absorbent component (100).
    Type: Grant
    Filed: September 7, 2020
    Date of Patent: April 25, 2023
    Assignee: MAS INNOVATION (PRIVATE) LIMITED
    Inventors: Deeyayawaththe Gedara Rumesh Mahela Kandegedara, Malnaida Marakkala Amitha Upamal, Agampodi Shyamal Akila De Silva
  • Endoscope surgery device
    Patent number: 11628035
    Abstract: An endoscope surgery device includes a vibration unit and a surgery unit. The vibration unit generates a vibration. The surgery unit includes a sheath and a surgery member. The sheath has a tube shape with a hollow extended in a longitudinal direction, and is entirely vibrated due to the vibration from the vibration unit with inserted into the ureter. The surgery unit passes through the hollow of the sheath, and is extended to an end of the sheath for an surgical procedures on the ureter.
    Type: Grant
    Filed: September 18, 2019
    Date of Patent: April 18, 2023
    Assignee: INDUSTRY-ACADEMIC COOPERATION FOUNDATION YONSEI UNIVERSITY
    Inventors: No Cheol Park, Kyo Chul Koo, Dongwook Kim
  • Preparation of psilocybin, different polymorphic forms, intermediates, formulations and their use
    Patent number: 11629159
    Abstract: This invention relates to the large-scale production of psilocybin for use in medicine. More particularly, it relates to a method of obtaining high purity crystalline psilocybin, particularly, in the form of Polymorph A. It further relates to a method for the manufacture of psilocybin and intermediates in the production thereof and formulations containing psilocybin.
    Type: Grant
    Filed: August 11, 2022
    Date of Patent: April 18, 2023
    Assignee: Compass Pathfinder Limited
    Inventors: Derek John Londesbrough, Christopher Brown, Julian Scott Northen, Gillian Moore, Hemant Kashinath Patil, David E. Nichols