Abstract: As a non-limiting example, various aspects of this disclosure provide embodiments of real-time heartbeat events detection using low-power, low-noise motion sensor.

Abstract: Described here are methods, devices, and systems for characterizing a physiological signal, and more specifically an electrocardiogram (ECG) signal. Generally, the method includes receiving an ECG signal generated by an ECG device coupled to a patient. The ECG signal may comprise a plurality of cardiac beat intervals. A set of evaluable replicates may be identified using a signal-to-noise ratio (SNR) for each cardiac beat, a repolarization signal, and an isoelectric line. Interval measurements may be determined from the set of evaluable multi-beat sequences. An ECG signal characteristic may be determined from the interval measurements.

Abstract: A method or system for facilitating the determining and setting of stimulation parameters for programming an electrical stimulation system using closed loop programming is provided. For example, pulse generator feedback logic is executed by a processor to interface with control instructions of an implantable pulse generator by incorporating one or more machine learning engines to automatically generate a proposed set of stimulation parameter values that each affect a stimulation aspect of the implantable pulse generator, receive one or more clinical responses and automatically generate a revised set of values taking into account the received clinical responses, and repeating the automated receiving of a clinical response and adjusting the stimulation parameter values taking the clinical response into account, until or unless a stop condition is reach or the a therapeutic response is indicated within a designated tolerance.

Abstract: A computer-implemented method for processing ECG data may include: receiving, over an electronic network, ECG data, wherein the ECG data represents a plurality of heartbeats; analyzing the ECG data, by at least one processor, to determine whether each of the plurality of heartbeats is a normal heartbeat or an abnormal heartbeat; associating, by the at least one processor, each of the abnormal heartbeats with either only one of a plurality of existing templates or a new template; receiving, from a user, input related to each new template, wherein the input includes either: a) a confirmation that the new template represents an abnormal heartbeat, or b) a reclassification of the new template as representing a normal heartbeat or a different abnormal heartbeat; and in response to the user input, updating, by the at least one processor, a label of each of the heartbeats associated with each confirmed new template and each of the heartbeats associated with each reclassified new template.

Abstract: A hermetically sealed filtered feedthrough assembly includes an electrically conductive ferrule sealed by a first gold braze to an insulator disposed at least partially within a ferrule opening. A conductive wire is disposed within a via hole disposed through the insulator extending from a body fluid side to a device side. A second gold braze hermetically seals the conductive leadwire to the via hole. A capacitor is disposed on the device side having a capacitor dielectric body with a dielectric constant k that is greater than 0 and less than 1000. The capacitor is the first filter capacitor electrically connected to the conductive leadwire coming from the body fluid side into the device side. An active electrical connection electrically connects the conductive leadwire to the capacitor active metallization. A ground electrical connection electrically connects the capacitor ground metallization to the ferrule and housing of the active implantable medical device.

Abstract: A feedthrough separates a body fluid side from a device side. A passageway is disposed through the feedthrough. A body fluid side leadwire extends from a first end disposed inside the passageway to a second end on the body fluid side. A device side leadwire extends from a first end disposed inside the passageway to a second end on the device side. The body fluid side leadwire is hermetically sealed to the feedthrough body and is not of the same material as the device side leadwire. A circuit board has an active via hole with a second end of the second leadwire residing therein. The circuit board has an active circuit trace that is electrically connectable to electronic circuits housed in an AIMD, and a circuit board ground metallization.

Abstract: Systems, devices, methods, and techniques relating to generating and presenting information related to heart rate data. In one aspect, a system includes a monitoring device configured to obtain physiological data for a living being and to generate annotation data based on the physiological data for a total time period, a processing system configured to obtain the annotation data via a communication channel from the monitoring device and to generate for display based on the annotation data a daily patient report that includes, a chart showing summary statistical data for a proportion of a total monitored time period spent in cardiac arrhythmia for each of a plurality of days and summary statistical data for a proportion of the total monitored time period not spent in cardiac arrhythmia for each of the plurality of days.

Abstract: Methods, systems, and devices for signal analysis in an implantable cardiac device such as an implantable cardioverter defibrillator. In illustrative examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. Analysis of the apparent width of detected events is used to determine whether overdetection is occurring. If overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data.

Abstract: In one aspect, the present invention provides a method of cooling to produce selective disruption of visceral fat tissue in a non-infant human subject comprising infusing a cooled fluid into the abdominal or peritoneal cavity, or into other parts of the body containing visceral fat, to cool the proximal tissue sufficiently to selectively disrupt lipid-rich cells therein, for example, to promote subsequent damage and absorption of lipid-rich cells by the body without producing unwanted effects in non-lipid-rich cells; e.g., without injury to internal organ tissues that could otherwise produce life-threating risks. The cooled fluid can be infused using a catheter arrangement. The cooled fluid can be retained within the abdominal category for a particular duration, and then drained using the catheter arrangement. In certain embodiments, the cooled fluid can be simultaneously introduced into the abdominal cavity and drained therefrom.

Abstract: This disclosure relates generally to PPG signal quality assessment, and more particularly to, a system and method for sensor agnostic PPG signal quality assessment using morphological analysis. In one embodiment, a method for PPG signal quality assessment includes obtaining a PPG signal captured using a testing device in real-time, and segmenting into a first plurality of PPG signal samples such that length of each of the first plurality of PPG signal samples more than a threshold length. A signal sufficiency check (SSC) is performed for each first PPG signal sample to obtain at least a first set of PPG signal samples complying with the SSC. A set of features is extracted from the first set of PPG signal samples, based on which each PPG signal sample is identified as one of a noisy and clean signal sample using a plurality of Random Forest (RF) models created during the training phase.

Abstract: An ablation catheter comprises an elongate catheter body and a branch electrode element. The elongate catheter body has a central axis, a distal end, and a proximal end. The elongate catheter body is configured to be steered within a heart chamber. The branch electrode element has a base end and a working end or tip. The base end is secured to the elongate catheter body at a location spaced proximally of the distal end and an effector on the working end. The branch electrode element is configured to evert when the distal end of the elongate catheter body is in a pulmonary vein ostium or os so that the effector can be selectively engaged against locations surrounding the pulmonary vein os which differ in radial direction and distance. One or more of linear or curved ablation patterns are generated on tissue adjacent the pulmonary vein os with the effector.

Abstract: Systems, devices and methods for providing a pressurized fluid for facilitating conductive gel release prior to providing cardiac therapy to a patient are disclosed. A first system can include a chemical reaction chamber including a first chemical and a second chemical isolated from each other by a mechanical barrier. The mechanical barrier is configured to be compromised upon receiving a signal from an electrotherapy device controller such that the first chemical and second chemical come into contact to produce a sufficient amount of pressurized fluid. An alternative system can include a pressure source comprising a reservoir containing a pressurized fluid. The pressure source can also include at least one release mechanism configured to cause a release of the pressurized fluid from the reservoir to an exit port of the pressure source when a wearable medical device is preparing to deliver a therapeutic shock to a patient.

Abstract: A filtered feedthrough assembly for an active implantable medical device (AIMD) includes an insulator hermetically sealed to an opening of an electrically conductive ferrule. A ceramic reinforced metal composite of platinum and alumina (CRMC) material is disposed in an insulator via hole surrounding a substantially pure platinum fill. A capacitor disposed on the insulator device side has a capacitor dielectric with a dielectric constant k that is greater than 0 and less than 1000. Coming from the body fluid side to the device side of the AIMD, the capacitor is the first filter capacitor electrically connected to the substantially pure platinum fill. An active electrical connection electrically connects the substantially pure platinum fill to the capacitor active metallization. A ground electrical connection electrically connects the capacitor ground metallization to the ferrule and subsequently to the housing of the AIMD.

Abstract: A method of interconnecting a conductor and a hermetic feedthrough of an implantable medical device includes welding a lead to a pad on a feedthrough. The feedthrough includes a ceramic insulator and a via hermetically bonded to the insulator. The via includes platinum. The pad is bonded to the insulator and electrically connected to the via, includes platinum, and has a thickness of at least 50 ?m. The lead includes at least one of niobium, platinum, titanium, tantalum, palladium, gold, nickel, tungsten, and oxides and alloys thereof.

Abstract: An implantable cardioverter defibrillator (ICD) performs a method that includes determining whether first criteria for detecting a ventricular tachyarrhythmia are met by a cardiac electrical signal. The ICD determines features from cardiac signal segment of a group of cardiac signal segments and determines whether a first portion of the features satisfy monomorphic waveform criteria and determines whether a second portion of the features satisfy supraventricular beat criteria. The ICD determines whether second criteria for detecting the ventricular tachyarrhythmia are met and withholds detecting of the ventricular tachyarrhythmia in response to the monomorphic waveform criteria and the supraventricular beat criteria being met.

Abstract: A method of transmitting wireless energy from an external energy transmitting device placed externally to a human body to an internal energy receiver placed internally in the human body. The method comprises applying to the external transmitting device electrical pulses from a first electric circuit to transmit the wireless energy, the electrical pulses having leading and trailing edges, varying the lengths of first time intervals between successive leading and trailing edges of the electrical pulses and/or the lengths of second time intervals between successive trailing and leading edges of the electrical pulses. The method further comprises transmitting wireless energy, the transmitted energy generated from the electrical pulses having a varied power, the varying of the power depending on the lengths of the first and/or second time intervals.

Abstract: A testing system and method for providing a testing system includes a user interface having a display for displaying information relating to measurements of health data and an input device for receiving information from a user relating to the health data. Provided in connection with the user interface is an autologging feature adapted to provide the user with user-selectable options on the display. Also provided is a statistical operation adapted to provide the user with enhanced information relating to the measurements of health data. Also provided is at least one indicator for indicating information relating to the number of health data readings that are within a target range, the number of health data readings that are above the target range and the number of health data readings that are below the target range.

Abstract: An electric stimulator for heart (as in heart pacemakers), brain (as in DBS), organs and general cells, with a supporting structure where there exists a plurality of electrically isolated electrodes called passive electrodes or field-shaping electrodes that are located under the surface of the supporting structure. The passive electrodes are controlled by an appropriate electronics control unit and powered by some electric energy storage, as a battery. Passive or field-shaping electrodes are electrically insulated, being unable to inject current in the surrounding medium, but they are capable of shaping the electric field in the space surrounding the electrodes, which has consequence on the path of the stimulating currents injected by other devices or by the organism itself. The invention also discloses locating the passive electrodes on surfaces that surround the desired target volume.

Abstract: An electric stimulator for heart (as in heart pacemakers), brain (as in DBS), organs and general cells, with a supporting structure where there exists a plurality of electrically isolated electrodes called passive electrodes or field-shaping electrodes that are located under the surface of the supporting structure. The passive electrodes are controlled by an appropriate electronics control unit and powered by some electric energy storage, as a battery. Passive or field-shaping electrodes are electrically insulated, being unable to inject current in the surrounding medium, but they are capable of shaping the electric field in the space surrounding the electrodes, which has consequence on the path of the stimulating currents injected by other devices or by the organism itself. The invention also discloses locating the passive electrodes at different depths from the surface of the supporting structure.

Abstract: Described herein are apparatuses and methods that improve conductive communication between an external programmer and an implantable medical device (IMD) that is implanted within a patient. In an embodiment, an auxiliary apparatus of the present technology includes a first auxiliary skin electrode configured to attach to skin of a patient, a second auxiliary skin electrode configured to attach to skin of a patient, and an electrically conductive path extending between the first and second auxiliary skin electrodes and interrupted by a capacitor. The auxiliary apparatus is distinct from the external programmer and the IMD, and can beneficially be used to improve conductive communication therebetween without making any modifications to the external programmer, and without making any modifications to the IMD.