Abstract: Electrophoresis Compositions, methods and kits useful for, among other things, detecting, quantifying and/or characterizing analytes are provided. The compositions are useful as electrophoresis standards for determine the isoelectric point and molecular weight of an analyte. The electrophoresis standards generally comprise at least one label moiety and one or more reactive moieties that when activated attach the standard to a substrate.

Abstract: There is provided a biosensor measurement system which can output a highly-precise measurement result even when an impact such as falling of the sensor occurs or the biosensor is an exposed sensor. An abnormal waveform detection electrode is provided in addition to electrodes for quantitative determination of a target substance. Therefore, when an impact is caused by such as falling of the sensor in a halt period where no voltage is applied in a voltage application algorithm, the abnormal waveform detection electrode can detect the impact. Further, also an exposed sensor can be detected by the abnormal waveform which is detected by the abnormal waveform detection electrode.

Abstract: Polyacrylamide gels that offer high resolution as electrophoretic media for protein separations and an improved resistance to hydrolysis upon storage are made by including either taurine, asparagine, or both as an ampholyte, in combination with either tris(hydroxymethyl)-aminomethane or bis(2-hydroxyethyl)amino-tris(hydroxymethyl)methane as a buffer, plus other conventional components.

Abstract: An electrochemical-based analytical test strip for the determination of an analyte (e.g., glucose) in a bodily fluid sample (such as a whole blood sample) includes an electrically insulating base layer and a patterned conductor layer (for example, a gold patterned conductor layer) disposed over the electrically-insulating layer. The patterned conductor layer includes at least one electrode with the electrode having electrochemically inert areas and an electrochemically active area(s). Moreover, the electrochemically inert areas and electrochemically active area(s) are of a predetermined size and a predetermined distribution such that electrochemical response of the electrode during use of the electrochemical-based analytical test strip is essentially equivalent to a predetermined electrochemical response.

Abstract: The present invention provides a nano-fluidic field effective device. The device includes a channel having a first side and a second side, a first set of electrodes adjacent to the first side, a second set of electrodes adjacent to the second side, a control unit for applying electric potentials to the electrodes and a fluid within the channel containing a charge molecule. The first set of electrodes is disposed such that application of electric potentials produces a spatially varying electric field that confines a charged molecule within a predetermined area of said channel. The second set of electrodes is disposed such that application of electric potentials relative to the electric potentials applied to the first set of electrodes creates an electric field that confines the charged molecule to an area away from the second side of the channel.

Abstract: A free-standing metallic article, and method of making, is disclosed in which the metallic article is electroformed on an electrically conductive mandrel. The metallic article has a plurality of electroformed elements that are configured to serve as an electrical conduit for a photovoltaic cell. A first electroformed element has at least one of: a) a non-uniform width along a first length of the first element, b) a change in conduit direction along the first length of the first element, c) an expansion segment along the first length of the first element, d) a first width that is different from a second width of a second element in the plurality of electroformed elements, e) a first height that is different from a second height of the second element in the plurality of electroformed elements, and f) a top surface that is textured.

Abstract: A wafer carrier is described. In one embodiment, the wafer carrier includes a variable aperture shield. The wafer carrier may include an electrically conductive wafer plating jig base having a plurality of concentric overlapping cavities of different depths, each cavity configured to receive a semiconductor wafer of a different size, a plurality of concentric magnetic attractors, at least one positioned within each of the plurality of overlapping cavities, and a cover plate comprising an open center surrounded by a support, the cover plate comprising an attractive material positioned within the support adjacent to the open center and aligned with at least one of the magnetic attractors when the cover plate is positioned over the wafer plating jig base.

Abstract: An electrochemical-based analytical test strip for the determination of an analyte (e.g., glucose) in a bodily fluid sample (such as a whole blood sample) includes an electrically insulating base layer and a patterned conductor layer (for example, a gold patterned conductor layer) disposed over the electrically-insulating layer. The patterned conductor layer includes at least one electrode with the electrode having electrochemically inert areas and an electrochemically active area(s). Moreover, the electrochemically inert areas and electrochemically active area(s) are of a predetermined size and a predetermined distribution such that electrochemical response of the electrode during use of the electrochemical-based analytical test strip is essentially equivalent to a predetermined electrochemical response.

Abstract: The invention relates to a catalytic coating suitable for oxygen-evolving anodes in electrochemical processes. The catalytic coating comprises an outermost layer with an iridium and tantalum oxide-based composition modified with amounts not higher than 5% by weight of titanium oxide.

Abstract: [Problem] To provide a plating method and apparatus which do not require preparation of a separate treatment tank for each treatment step and therefore enable the facility to be reduced in size and, further, which can reduce the amounts of use of the treatment solutions. [Solution] A plating apparatus feeding a plating solution to a treatment tank in which an electrode is arranged and plating a workpiece made of a metal so as to perform plating, the plating apparatus characterized by being provided with a plurality of pipes which are connected to an outer wall of the treatment tank and a switch valve which is provided able to rotate at an inner side of the outer wall and which has at least one feed port for making at least one treatment solution feed pipe selected from the plurality of treatment solution feed pipes communicate with the treatment tank.

Abstract: An eye-mountable device includes an electrochemical sensor embedded in a polymeric material configured for mounting to a surface of an eye. The electrochemical sensor applies a stabilization voltage between a working electrode and a reference electrode to allow the amperometric current to stabilize before powering measurement electronics configured to measure the amperometric current and communicate the measured amperometric current. The electrochemical sensor consumes less power while applying the stabilization voltage than during the measurement. The measurement is initiated in response to receiving a measurement signal at an antenna in the eye-mountable device.

Abstract: An electrochemical paper-immunosensor and method for detecting aminoglycoside antibiotics is developed in the present invention. Single-walled carbon nanotubes are coated on the common filtration paper by dip-dry cycles. With antibody against neomycin adding to the coating solution, a high sensitive biosensor for specific detection of neomycin is prepared, satisfying to the rigid authority regulations. The sensor is not only sensitive but also rapid, comparing with the classic ELISA method, with LOD of 0.04 ng mL?1 and the whole detection process lasting less than 30 min. Another notable advantage of this invention is the versatility of the sensor, similar method is engaged to prepare the versatile sensor for other aminoglycoside antibiotics, replacement with relevant antibodies.

Abstract: The present invention relates to a cell-based transparent sensor capable of the real-time optical observation of cell behavior, to a method for manufacturing same, and to a multi-detection sensor chip using same. More particularly, the present invention relates to a cell-based transparent sensor capable of the real-time optical observation of cell behavior, to a method for manufacturing same, and to a multi-detection sensor chip using same, wherein the sensor can sense the ionic concentration of an electrolyte in accordance with the variation in the metabolic activity of cells using an ion-selective field effect transistor (ISFET) sensor and an electrochemical sensor, and the sensor is made of a transparent material which enables real-time observations of optical phenomenon for measurement of cell behavior.

Abstract: A system and method for generating and collecting data to detect and evaluate corrosion in a conductive metal beneath a protective coating is disclosed. A semi-integrated electrode having a reference electrode and a counter electrode is connected to a portable hand held device, such as a portable potentiostat generator. That device is also connected electrically to the metal being evaluated with the metal forming a working electrode. The counter electrode is physically and electrically separate from the metal, and a signal or voltage potential is provided therebetween through an electrolyte solution, such as sea water. The system and method is practiced without need for a container for an electrolyte solution. Data are collected and displayed indicating corrosion.

Abstract: Devices and methods for detecting the length of analytes, and/or sequencing analytes are provided in which two or more electrical signals are obtained as an analyte traverses a fluidic channel. Detection of the relative position of probes hybridized to a biopolymer and/or the length of the analyte (e.g., a biopolymer) does not rely on the absolute time between detection events of a given electrical signal to determine a distance associated with the biopolymer. Instead, multiple signals are obtained as functions of time) corresponding to a plurality of detector volumes at known locations along a fluidic channel through which the biopolymer passes, and the distances are determined from the multiple signals.

Abstract: A steel reinforced concrete protector in an anode cavity such as a cored hole, drilled hole or cut chase is disclosed. The protector includes a sacrificial anode assembly and a separate backfill. The sacrificial anode assembly includes a sacrificial metal element and an activator to maintain an activity of the sacrificial metal element and at least one spacer. The spacer prevents the sacrificial metal element and the activator from contacting the surface of the anode cavity. The spacer and the sacrificial metal element have a coupling mechanism which facilitates connection of the sacrificial metal element to the spacer. The backfill is a pliable and viscous material which contains an electrolyte and fills the spaces between the sacrificial anode assembly and the anode cavity wall. The invention also relates to a pre-packaged sacrificial anode assembly to increase the shelf life of the assembly.

Abstract: A plating fixture that affords improved control and process repeatability of the placement of material on a surface of a terminal lead is described. The thereby plated terminal lead is further incorporatable into an electrochemical cell. The plating fixture consists of a membrane that prevents migration of the electroplating chemicals along areas of the lead that are not desired. Furthermore, the fixture utilizes a setup plate that controls the length of the lead that is plated.

Abstract: A sample substance S is captured by a capture substance 10 which is immobilized on a working electrode body 161 to provide a method of electrochemically detecting a sample substance capable of detecting the sample substance with high sensitivity. A complex which includes, on a soluble carrier 21, a sample substance S and a labeled binder 20 that has a modified labeled substance 23 containing a labeled substance 20 bound to modified labeled substance 23 containing a labeled substance 24 and a binder 22 that binds to the sample substance S, formed on the working electrode 161. The soluble carrier 21 is dissolved, and the modified labeled substance 23 is attracted to the working electrode 161.

Abstract: A free-standing metallic article, and method of making, is disclosed in which the metallic article is electroformed on an electrically conductive mandrel. The mandrel has an outer surface with a preformed pattern, wherein at least a portion of the metallic article is formed in the preformed pattern. The metallic article is separated from the electrically conductive mandrel, which forms a free-standing metallic article that may be coupled with the surface of a semiconductor material for a photovoltaic cell.

Abstract: An electrochemical test sensor (10) for determining an analyte in a fluid sample, includes a base (12) and a second layer. The base (12) includes a plurality of electrodes (30,32), a working conductive lead (42) and a counter conductive lead (40) thereon. The electrodes include a working electrode (32) and a counter electrode (30). The second layer (20) assists in forming a channel (22) in which the channel includes a reagent therein. Auto-calibration information of the test sensor is performed by a plurality of auto-calibration segments (75) connected to one of the following: the working conductive lead (42), the counter conductive lead (40), or neither of the conductive leads, at least one of the plurality of auto-calibration segments (75a) being connected to the working conductive lead (42) and at least one of the plurality of auto-calibration segments (75b) being connected to the counter conductive lead (40).